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33
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35948967678
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In analogy with the ome nomencalture in the biological arena, the synthome is the complete set of reactions available to the chemist for the synthesis of molecules of interest
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In analogy with the "ome" nomencalture in the biological arena, the synthome is the complete set of reactions available to the chemist for the synthesis of molecules of interest.
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N-Aryl-substituted ketone 11 prepared according to: (d) Zhao, M.-X.; Goeddel, D.; Li, K.; Shi, Y. Tetrahedron 2006, 62, 8064.
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N-Aryl-substituted ketone 11 prepared according to: (d) Zhao, M.-X.; Goeddel, D.; Li, K.; Shi, Y. Tetrahedron 2006, 62, 8064.
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47
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35948965331
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The absolute stereochemistry was established by comparing the HPLC trace of 13 derived from 12 to that of ent-13 by removal of the chiral auxiliary from 15, the stereochemistry of which was established by X-ray crystallography of 17.
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The absolute stereochemistry was established by comparing the HPLC trace of 13 derived from 12 to that of ent-13 by removal of the chiral auxiliary from 15, the stereochemistry of which was established by X-ray crystallography of 17.
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