Investigation on the clinical efficacy and tolerability of a 0.4% topical stannous fluoride preparation (MedEquine® Gel) for the treatment of bacterial skin infections in horses: A prospective, randomized, double-blinded, placebo-controlled clinical trial

Veterinary Dermatology

Volumn 18, Issue 6, 2007, Pages 444-450

  Marsella, Rosanna ^a   Akucewich, Lisa ^a  

^a University of Florida College of Veterinary Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; TIN FLUORIDE;

ANIMAL; ANIMAL DISEASE; ARTICLE; BACTERIAL SKIN DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; GEL; HORSE; HORSE DISEASE; HOSPITALIZATION; INTRADERMAL DRUG ADMINISTRATION; MALE; PATHOLOGY; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTI-BACTERIAL AGENTS; DOUBLE-BLIND METHOD; FEMALE; GELS; HORSE DISEASES; HORSES; MALE; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; SKIN DISEASES, BACTERIAL; TIN FLUORIDES; TREATMENT OUTCOME;

ANIMALIA; BACTERIA (MICROORGANISMS); EQUIDAE;

EID: 35948968047     PISSN: 09594493     EISSN: 13653164     Source Type: Journal    
DOI: 10.1111/j.1365-3164.2007.00623.x     Document Type: Article

References (17)

1. Scott DW, Miller WH. Bacterial skin diseases. In : Scott DW, Miller WH, eds. Equine Dermatology. London : Saunders, 2003 : 206 27.
2. Fadok VA. Overview of equine papular and nodular dermatoses. Veterinary Clinics of North America: Equine Practice 1995 11 : 61 74.
3. Ford RB, Cairns RA, Short CD. Equine dermatophilosis: a two-year clinico-pathologic study. Veterinary Medicine Small Animal Clinician 1974 69 : 1557 61.
4. Chiers K, Decostere A, Devriese LA et al. Bacteriological and mycological findings, and in vitro antibiotic sensitivity of pathogenic staphylococci in equine skin infections. Veterinary Record 2003 152 : 138 41.
5. Van Duijkeren E, Vulto AG, Van Miert AS. Trimethoprim/sulfonamide combinations in the horse: a review. Journal of Veterinary Pharmacology and Therapeutics 1994 17 : 64 73.
6. McLinn S. Topical mupirocin vs. systemic erythromycin treatment for pyoderma. The Pediatric Infectious Disease Journal 1988 7 : 785 90.
7. Eells LD, Mertz PM, Piovanetti Y et al. Topical antibiotic treatment of impetigo with mupirocin. Archives of Dermatology 1986 122 : 1273 6.
8. White DJ, Kozak KM, Gibb R et al. A 24-hour dental plaque prevention study with a stannous fluoride dentifrice containing hexametaphosphate. Journal of Contemporary Dental Practice 2006 7 : 1 11.
9. Spann CT, Tutrone WD, Weinberg JM et al. Topical antibacterial agents for wound care: a primer. Dermatologic Surgery 2003 29 : 620 6.
10. Van Loveren C. Antimicrobial activity of fluoride and its in vivo importance: identification of research questions. Caries Research 2001 35 : 65 70.
11. Ooosterwaal PJ, Mikx FH, van't Hof MA et al. Short term bactericidal activity of chlorhexidine gel, stannous fluoride and amine fluoride gel tested in periodontal pockets. Journal of Clinical Periodontology 1991 18 : 97 100.
12. Quirynen M, De Soete M, Pauwels M et al. Can toothpaste or a toothbrush with antibacterial tufts prevent toothbrush contamination? Journal of Periodontology 2003 74 : 312 22.
13. Tseng CC, Wolff LF, Aeppli DM. Effects of gels containing stannous fluoride on oral bacteria-an in-vitro study. Australian Dental Journal 1992 37 : 368 73.
14. Ferguson EA, Littlewood JD, Carlotti DN et al. Management of canine atopic dermatitis using the plant extract PYM00217: a randomized, double-blind, placebo-controlled clinical study. Veterinary Dermatology 2006 17 : 236 43.
15. Silny W, Czarnecka-Operacz M, Silny P. The new scoring system for evaluation of skin inflammation extent and severity in patients with atopic dermatitis. Acta Dermatovenerologica Croatica 2005 13 : 219 24.
16. Greiner EC, Fadok VA, Rabin EB. Equine culicoides hypersensitivity in Florida: biting midges aspirated from horses. Medical and Veterinary Entomology 1990 4 : 375 81.
17. Ambrose NC. The pathogenesis of dermatophilosis. Tropical Animal Health and Production 1996 28 : 29S 37S.