Up-regulation of indoleamine 2,3-dioxygenase by lipopolysaccharide is regulated through activation of p38 mitogen-activated protein kinase and nuclear factor-κB

International Congress Series

Volumn 1304, Issue , 2007, Pages 200-204

  Fujigaki, Suwako ^a   Takahashi, Kanako ^a   Fujigaki, Hidetsugu ^a   Takemura, Masao ^a   Seishima, Mitsuru ^a   Saito, Kuniaki ^a  

^a GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Indoleamine 2,3 dioxygenase; Interferon regulatory factor 1; Lipopolysaccharide; Signal transducer and activator of transcription 1

Indexed keywords

EID: 35948962237     PISSN: 05315131     EISSN: None     Source Type: Book Series    
DOI: 10.1016/j.ics.2007.07.032     Document Type: Article

References (5)

1. Fujigaki S., et al. M. Lipopolysaccharide induction of indoleamine 2,3-dioxygenase is mediated dominantly by an IFN-gamma-independent mechanism. Eur. J. Immunol. 31 (2001) 2313-2318
2. Saito K., et al. Early increases in TNF-alpha, IL-6 and IL-1 beta levels following transient cerebral ischemia in gerbil brain. Neurosci. Lett. 206 (1996) 149-152
3. Fujigaki H., et al. The signal transducer and activator of transcription 1alpha and interferon regulatory factor 1 are not essential for the induction of indoleamine 2,3-dioxygenase by lipopolysaccharide: involvement of p38 mitogen-activated protein kinase and nuclear factor-kappaB pathways, and synergistic effect of several proinflammatory cytokines. J. Biochem. (Tokyo) 139 4 (2006) 655-662
4. FitzGerald M.J., et al. Rapid DNA binding by nuclear factor kappa B in hepatocytes at the start of liver regeneration. Cell Growth Differ. 6 (1995) 417-427
5. Munn D.H., et al. Inhibition of T cell proliferation by macrophage tryptophan catabolism. J. Exp. Med. 189 (1999) 1363-1372