Vectorial reconstruction of retinal blood flow in three dimensions measured with high resolution resonant Doppler Fourier domain optical coherence tomography

Journal of Biomedical Optics

Volumn 12, Issue 4, 2007, Pages

  Michaely, Roland ^a   Bachmann, Adrian H ^a   Villiger, Martin L ^a   Blatter, Cédric ^a   Lasser, Theo ^a   Leitgeb, Rainer A ^a  

^a EPFL   (Switzerland)

Author keywords

Doppler; Fourier domain; Optical coherence tomography; Retinal blood flow

Indexed keywords

AXIAL FLOW; BLOOD; COMPUTER SIMULATION; FEATURE EXTRACTION; FLOW VELOCITY; MEDICAL IMAGING; OPHTHALMOLOGY;

FOURIER DOMAIN OPTICAL COHERENCE TOMOGRAPHY; RETINAL BLOOD FLOW; VASCULARIZATION STRUCTURE;

OPTICAL TOMOGRAPHY;

ALGORITHM; ARTICLE; BLOOD FLOW VELOCITY; COMPUTER ASSISTED DIAGNOSIS; EVALUATION; FOURIER ANALYSIS; HISTOLOGY; HUMAN; IMAGE ENHANCEMENT; METHODOLOGY; OPTICAL COHERENCE TOMOGRAPHY; PHYSIOLOGY; REPRODUCIBILITY; RETINA BLOOD VESSEL; RETINOSCOPY; SENSITIVITY AND SPECIFICITY;

ALGORITHMS; BLOOD FLOW VELOCITY; FOURIER ANALYSIS; HUMANS; IMAGE ENHANCEMENT; IMAGE INTERPRETATION, COMPUTER-ASSISTED; REPRODUCIBILITY OF RESULTS; RETINAL VESSELS; RETINOSCOPY; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 35948958202     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.2771553     Document Type: Article

References (27)

1. A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. Elzaiat, "Measurement of intraocular distances by backscattering spectral interferometry," Opt. Commun. 117, 43-48 (1995).
2. M. Wojtkowski, R. Leitgeb, A. Kowalczyk, T. Bajraszewski, and A. F. Fercher, "In vivo human retinal imaging by Fourier domain optical coherence tomography," J. Biomed. Opt. 7(3), 457-463 (2002).
3. R. A. Leitgeb, W. Drexler, A. Unterhuber, B. Hermann, T. Bajraszewski, T. Le, A. Stingl, and A. F. Fercher, "Ultrahigh resolution Fourier domain optical coherence tomography," Opt. Express 12, 2156-2165 (2004).
4. N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo highresolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Opt. Express 12, 367-376 (2004).
5. M. Wojtkowski, V. J. Srinivasan, T. H. Ko, J. G. Fujimoto, A. Kowalczyk, and J. S. Duker, "Ultrahigh-resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation," Opt. Express 12, 2404-2422 (2004).
6. J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, "Improved signal-to-noise ratio inspectral-domain compared with time-domain optical coherence tomography," Opt. Lett. 28, 2067-2069 (2003).
7. U. Schmidt-Erfurth, R. A. Leitgeb, S. Michels, B. Povazay, S. Sacu, B. Hermann, C. Ahlers, H. Sattmann, C. Scholda, A. F. Fercher, and W. Drexler, "Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases," Invest. Ophthalmol. Visual Sci. 46, 3393-3402 (2005). (Pubitemid 44264330)
8. R. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, "Performance of Fourier domain vs. time domain optical coherence tomography," Opt. Express 11, 889-894 (2003).
9. M. Wojtkowski, V. Srinivasan, J. G. Fujimoto, T. Ko, J. S. Schuman, A. Kowalczyk, and J. S. Duker, "Three-dimensional retinal imaging with high-speed ultrahigh-resolution optical coherence tomography," Ophthalmology 112, 1734-1746 (2005). (Pubitemid 41400010)
10. R. A. Leitgeb, B. Hermann, B. Povazay, H. Sattmann, S. Michels, U. Schmidt-Erfurt, and W. Drexler, "Spectroscopic analysis of the human retina using three-dimensional spectroscopic ultrahigh resolution optical coherence tomography," Invest. Ophthalmol. Visual Sci. 46, 3393-3402 (2005).
11. B. H. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. J. Tearney, B. E. Bouma, and J. F. de Boer, "Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 13 -m," Opt. Express 13, 3931-3944 (2005). (Pubitemid 40899287)
12. E. Gotzinger, M. Pircher, and C. K. Hitzenberger, "High speed spectral domain polarization sensitive optical coherence tomography of the human retina," Opt. Express 13, 10217-10229 (2005). (Pubitemid 41785232)
13. R. A. Leitgeb, L. Schmetterer, W. Drexler, A. F. Fercher, R. J. Zawadzki, and T. Bajraszewski, "Real-time assessment of retinal blood flow with ultrafast acquisition by color Doppler Fourier domain optical coherence tomography," Opt. Express 11, 3116-3121 (2003).
14. B. R. White, M. C. Pierce, N. Nassif, B. Cense, B. H. Park, G. J. Tearney, B. E. Bouma, T. C. Chen, and J. F. de Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express 11, 3490-3497 (2003).
15. J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieglstein, L. M. Serra, V. X. Renard, and E. Stefansson, "The impact of ocular blood flow in glaucoma," Prog. Retin Eye Res. 21, 359-393 (2002). (Pubitemid 34879080)
16. C. E. Riva, J. E. Grunwald, S. H. Sinclair, and B. L. Petrig, "Blood velocity and volumetric flow rate in human retinal vessels," Invest. Ophthalmol. Visual Sci. 26, 1124-1132 (1985). (Pubitemid 15003355)
17. L. Schmetterer and M. Wolzt, "Ocular blood flow and associated functional deviations in diabetic retinopathy," Diabetologia 42, 387-405 (1999). (Pubitemid 29148397)
18. C. E. Riva, S. D. Cranstoun, J. E. Grunwald, and B. L. Petrig, "Choroidal blood flow in the foveal region of the human disc," Invest. Ophthalmol. Visual Sci. 35, 4273-4281 (1994). (Pubitemid 24377498)
19. S. Makita, Y. Hong, M. Yamanari, T. Yatagai, and Y. Yasuno, "Optical coherence angiography," Opt. Express 14, 7821-7840 (2006). (Pubitemid 44277517)
20. H. W. Ren, K. M. Brecke, Z. H. Ding, Y. H. Zhao, J. S. Nelson, and Z. P. Chen, "Imaging and quantifying transverse flow velocity with the Doppler bandwidth in a phase-resolved functional optical coherence tomography," Opt. Lett. 27, 409-411 (2002). (Pubitemid 34617958)
21. D. P. Dave and T. E. Milner, "Doppler-angle measurement in highly scattering media," Opt. Lett. 25, 1523-1525 (2000).
22. A. H. Bachmann, M. L. Villiger, C. Blatter, T. Lasser, and R. A. Leitgeb, "Resonant Doppler flow imaging and optical vivisection of retinal blood vessels," Opt. Express 15, 408-422 (2007). (Pubitemid 46168485)
23. R. A. Leitgeb, L. Schmetterer, C. K. Hitzenberger, A. F. Fercher, F. Berisha, M. Wojtkowski, and T. Bajraszewski, "Real-time measurement of in vitro flow by Fourier-domain color Doppler optical coherence tomography," Opt. Lett. 29, 171-173 (2004).
24. M. A. Choma, A. K. Ellerbee, C. Yang, T. L. Creazzo, and J. A. Izatt, "Spectral-domain phase microscopy," Opt. Lett. 30, 1162-1164 (2005). (Pubitemid 40795094)
25. S. H. Yun, G. J. Tearney, J. F. de Boer, and B. E. Bouma, "Motion artifacts in optical coherence tomography with frequency-domain ranging," Opt. Express 12, 2977-2998 (2004).
26. P. Thévenaz, U. E. Ruttimann, and M. Unser, "A pyramid approach to subpixel registration based on intensity," IEEE Trans. Image Process. 7(1), 27-41 -Jan. 1998), see http://bigwww.epfl.ch/publications/ thevenaz9801.html. (Pubitemid 128745320)
27. K. S. Arun, T. S. Huang, and S. D. Blostein, "Least-squares fitting of two 3-D point sets," IEEE Trans. Pattern Anal. Mach. Intell. 9(5), 698-670 (1987).