Spectral oximetry assessed with high-speed ultra-highresolution optical coherence tomography

Journal of Biomedical Optics

Volumn 12, Issue 4, 2007, Pages

  Kagemann, Larry ^a,b   Wollstein, Gadi ^a   Wojtkowski, Maciej ^c,d   Ishikawa, Hiroshi ^a,b   Townsend, Kelly A ^a   Gabriele, Michelle L ^a,b   Srinivasan, Vivek J ^c   Fujimoto, James G ^c   Schuman, Joel S ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b University of Pittsburgh   (United States)

^c USA   (United States)

^d NICOLAUS COPERNICUS UNIVERSITY   (Poland)

Author keywords

Metabolism; Optical coherence tomography; Oximetry; Oxygen; Retina; Spectroscopy

Indexed keywords

BLOOD; DENSITY (OPTICAL); MEDICAL IMAGING; METABOLISM; OPHTHALMOLOGY; OXIMETERS; SCANNING; TISSUE;

OPTICAL DENSITY RATIO; OXIMETRY; RETINA;

OPTICAL TOMOGRAPHY;

ALGORITHM; ARTICLE; BLOOD FLOW VELOCITY; COMPUTER ASSISTED DIAGNOSIS; HISTOLOGY; HUMAN; IMAGE ENHANCEMENT; METHODOLOGY; OPTICAL COHERENCE TOMOGRAPHY; OXIMETRY; PHYSIOLOGY; REPRODUCIBILITY; RETINA BLOOD VESSEL; RETINOSCOPY; SENSITIVITY AND SPECIFICITY;

ALGORITHMS; BLOOD FLOW VELOCITY; HUMANS; IMAGE ENHANCEMENT; IMAGE INTERPRETATION, COMPUTER-ASSISTED; OXIMETRY; REPRODUCIBILITY OF RESULTS; RETINAL VESSELS; RETINOSCOPY; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 35948939354     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.2772655     Document Type: Article

References (34)

1. R. Y. Foos, "Regional ischemic infarcts of the retina," Albrecht von Graefes Arch. Klin. Exp. Ophthalmol. 200, 183-194 (1976).
2. M. Shimo-Oku and S. Miyazaki, "Acute anterior and posterior ischemic optic neuropathy," Jpn. J. Ophthalmol. 28, 159-170 (1984). (Pubitemid 14122845)
3. S. S. Hayreh and P. Podhajsky, "Ocular neovascularization with retinal vascular occlusion. II. Occurrence in central and branch retinal artery occlusion," Arch. Ophthalmol. (Chicago) 100, 1585-1596 (1982). (Pubitemid 12032524)
4. R. A. Ashman, F. Reinholz, and R. H. Eikelboom, "Oximetry with a multiple wavelength SLO," Int. Ophthalmol. 23, 343-346 (2001). (Pubitemid 34256600)
5. J. P. de Kock, L. Tarassenko, C. J. Glynn, and A. R. Hill, "Reflectance pulse oximetry measurements from the retinal fundus," IEEE Trans. Biomed. Eng. 40, 817-823 (1993). (Pubitemid 24060731)
6. S. H. Hardarson, A. Harris, R. A. Karlsson, et al., "Automatic retinal oximetry," Invest. Ophthalmol. Visual Sci. 47, 5011-5016 (2006). (Pubitemid 46586407)
7. J. B. Hickam and J. C. Ross, "An improved method for photographic measurement of retinal venous blood oxygen," Tech. Doc. Rep. SAMTDR USAF Sch. Aerosp. Med. 62-64, 5p.:5p (1962).
8. J. B. Hickam, R. Frayser, and J. C. Ross, "A. study of retinal venous blood oxygen saturation in human subjects by photographic means," Circulation 27, 375-385 (1963).
9. J. Sebag, F. C. Delori, G. T. Feke, and J. J. Weiter, "Effects of optic atrophy on retinal blood flow and oxygen saturation in humans," Arch. Ophthalmol. (Chicago) 107, 222-226 (1989). (Pubitemid 19055341)
10. J. S. Tiedeman, S. E. Kirk, S. Srinivas, and J. M. Beach, "Retinal oxygen consumption during hyperglycemia in patients with diabetes without retinopathy," Ophthalmology 105, 31-36 (1998). (Pubitemid 28070599)
11. D. J. Faber, E. G. Mik, M. C. Aalders, and T. G. van Leeuwen, "Light absorption of -oxy-hemoglobin assessed by spectroscopic optical coherence tomography," Opt. Lett. 28, 1436-1438 (2003).
12. D. J. Faber, M. C. Aalders, E. G. Mik, B. A. Hooper, M. J. van Gemert, and T. G. van Leeuwen, "Oxygen saturation-dependent absorption and scattering of blood," Phys. Rev. Lett. 93, 028102 (2004).
13. D. J. Faber, E. G. Mik, M. C. Aalders, and T. G. van Leeuwen, "Toward assessment of blood oxygen saturation by spectroscopic optical coherence tomography," Opt. Lett. 30, 1015-1017 (2005). (Pubitemid 40749267)
14. M. M. Frojmovic and R. Panjwani, "Blood cell structure-function studies: light transmission and attenuation coefficients of suspensions of blood cells and model particles at rest and with stirring," J. Lab. Clin. Med. 86, 326-343 (1975).
15. C. Pitris, M. E. Brezinski, B. E. Bouma, G. J. Tearney, J. F. Southern, and J. G. Fujimoto, "High resolution imaging of the upper respiratory tract with optical coherence tomography: a feasibility study," Am. J. Respir. Crit. Care Med. 157, 1640-1644 (1998).
16. X. D. Li, S. A. Boppart, D. J. Van, et al., "Optical coherence tomography: advanced technology for the endoscopic imaging of Barrett's esophagus," Endoscopy 32, 921-930 (2000).
17. W. Drexler, H. Sattmann, B. Hermann, et al., "Enhanced visualization of macular pathology with the use of ultrahigh-resolution optical coherence tomography," Arch. Ophthalmol. (Chicago) 121, 695-706 (2003). (Pubitemid 36554473)
18. M. Gloesmann, B. Hermann, C. Schubert, H. Sattmann, P. K. Ahnelt, and W. Drexler, "Histologic correlation of pig retina radial stratification with ultrahigh-resolution optical coherence tomography," Invest. Ophthalmol. Visual Sci. 44, 1696-1703 (2003). (Pubitemid 36378600)
19. A. Unterhuber, B. Povazay, B. Hermann, et al., "Compact, low-cost Ti:Al2O3 laser for in vivo ultrahigh-resolution optical coherence tomography," Opt. Lett. 28, 905-907 (2003).
20. E. M. Anger, A. Unterhuber, B. Hermann, et al., "Ultrahigh resolution optical coherence tomography of the monkey fovea. Identification of retinal sublayers by correlation with semithin histology sections," Exp. Eye Res. 78, 1117-1125 (2004). (Pubitemid 38510349)
21. W. Drexler, "Ultrahigh-resolution optical coherence tomography," J. Biomed. Opt. 9, 47-74 (2004).
22. W. Drexler, "Methodological advancements. Ultrahigh-resolution OCT," Ophthalmologe 101, 804-812 (2004).
23. M. Wojtkowski, R. Leitgeb, A. Kowalczyk, T. Bajraszewski, and A. F. Fercher, "In vivo human retinal imaging by Fourier domain optical coherence tomography," J. Biomed. Opt. 7, 457-463 (2002).
24. M. Wojtkowski, V. Srinivasan, J. G. Fujimoto, et al., "Threedimensional retinal imaging with high-speed ultrahigh-resolution optical coherence tomography," Ophthalmology 112, 1734-1746 (2005). (Pubitemid 41400010)
25. D. C. Adler, T. H. Ko, and J. G. Fujimoto, "Speckle reduction in optical coherence tomography images by use of a spatially adaptive wavelet filter," Opt. Lett. 29, 2878-2880 (2004). (Pubitemid 40011254)
26. R. Huber, D. C. Adler, and J. G. Fujimoto, "Buffered Fourier domain mode locking: unidirectional swept laser sources for optical coherence tomography imaging at 370,000 lines/s," Opt. Lett. 31, 2975-2977 (2006). (Pubitemid 44664580)
27. V. J. Srinivasan, M. Wojtkowski, A. J. Witkin, et al., "High-definition and 3-dimensional imaging of macular pathologies with high-speed ultrahigh-resolution optical coherence tomography," Ophthalmology 113, 2054.e1-14 (2006).
28. M. Wojtkowski, T. Bajraszewski, P. Targowski, and A. Kowalczyk, "Real-time in vivo imaging by high-speed spectral optical coherence tomography," Opt. Lett. 28, 1745-1747 (2003).
29. M. Wojtkowski, T. Bajraszewski, I. Gorczynska, et al., "Ophthalmic imaging by spectral optical coherence tomography," Am. J. Ophthalmol. 138, 412-419 (2004). (Pubitemid 39208568)
30. J. M. Beach, K. J. Schwenzer, S. Srinivas, D. Kim, and J. S. Tiedeman, "Oximetry of retinal vessels by dual-wavelength imaging: calibration and influence of pigmentation," J. Appl. Physiol. 86, 748-758 (1999). (Pubitemid 29075834)
31. M. Crittin, H. Schmidt, and C. E. Riva, "Hemoglobin oxygen saturation -So2) in the human ocular fundus measured by reflectance oximetry: preliminary data in retinal veins," Klin. Monatsbl. Augenheilkd. 219, 289-291 (2002). (Pubitemid 34625238)
32. S. Wray, M. Cope, D. T. Delpy, J. S. Wyatt, and E. O. Reynolds, "Characterization of the near infrared absorption spectra of cytochrome aa3 and haemoglobin for the non-invasive monitoring of cerebral oxygenation," Biochim. Biophys. Acta 933, 184-192 (1988). (Pubitemid 18086628)
33. H. Narasimha-Iyer, J. M. Beach, B. Khoobehi, J. Ning, H. Kawano, and B. Roysam, "Algorithms for automated oximetry along the retinal vascular tree from dual-wavelength fundus images," J. Biomed. Opt. 10, 54013 (2005).
34. F. C. Delori, "Noninvasive technique for oximetry of blood in retinal vessels," Appl. Opt. 27, 1113-1125 (1988). (Pubitemid 18093264)