3-Substituted 7-phenyl-pyrroloquinolinones show potent cytotoxic activity in human cancer cell lines

Journal of Medicinal Chemistry

Volumn 50, Issue 22, 2007, Pages 5509-5513

  Gasparotto, Venusia ^a   Castagliuolo, Ignazio ^a   Ferlin, Maria Grazia ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 PHENYLPYRROLO[2,3 H]QUINOLIN 4 ONE; 2 PHENYLQUINOLINONE DERIVATIVE; 7 PHENYLPYRROLO[3,2 F]QUINOLIN 9 ONE; COLCHICINE; FLAVONE DERIVATIVE; PACLITAXEL; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; VINCRISTINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER RESISTANCE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; FLUORESCENCE ACTIVATED CELL SORTING; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MICROTUBULE ASSEMBLY; REACTION OPTIMIZATION; SUBSTITUTION REACTION;

ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL LINE, TUMOR; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; FLOW CYTOMETRY; HUMANS; PACLITAXEL; PYRROLES; QUINOLONES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 35848958398     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm070534b     Document Type: Article

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