Development and validation of an HPLC-UV method for the determination of insulin in rat plasma: Application to pharmacokinetic study

Chromatographia

Volumn 66, Issue 9-10, 2007, Pages 805-809

  Ravi, Sheshala ^a   Peh, Kok Khiang ^a   Darwis, Yusrida ^a   Krishna Murthy, Bhavanasi ^a   Raghu Raj Singh, Thakur ^a  

^a SCHOOL OF PHARMACEUTICAL SCIENCES   (Malaysia)

Author keywords

Column liquid chromatography; Insulin; Methyl paraben; Pharmacokinetic study; Rat plasma

Indexed keywords

DICHLOROMETHANE; HEXANE; HUMAN INSULIN; INSULIN; METHYL PARABEN; MICROSPHERE; NEUTRAL INSULIN; STREPTOZOCIN;

ACCURACY; ACIDIC BACK EXTRACTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CALIBRATION; CONTROLLED STUDY; DEVICE; DIABETES MELLITUS; DISEASE MODEL; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG ISOLATION; EXTRACTION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ASSAY; RAT; ROOM TEMPERATURE; SINGLE DRUG DOSE; STREPTOZOCIN DIABETES; ULTRAVIOLET RADIATION; VALIDATION PROCESS;

EID: 35848951891     PISSN: 00095893     EISSN: 16121112     Source Type: Journal    
DOI: 10.1365/s10337-007-0402-8     Document Type: Article

References (12)

1. Crommelin DJA, Sindelar RD (1997) Pharmaceutical biotechnology. Harwood Academic Publishers, Netherlands
2. Lepore M, Pampanelli S, Fanelli C, Porcellati F, Bartocci L, Di Vincenzo A, Cordoni C, Costa E, Brunetti P, Bolli GB (2000) Diabetes 49:2142-2148
3. Martin GJ, Rand JS (2001) J Feline Med Surg 3:23-30
4. Takenaga M, Yamaguchi Y, Kitagawa A, Ogawa Y, Mizushima Y, Igarashi R (2002) J Pharm Pharmacol 54:1189-1194
5. Garcia-Contreras L, Morcol T, Bell SJD, Hickey AJ (2003) AAPS PharmSci 5:1-11
6. Sobey WJ, Beer SF, Carrington CA, Clark PM, Frank BH, Gray IP, Luzio SD, Owens DR, Schneider AE, Siddle K (1989) Biochem J 260:535-541
7. Clark PM, Levy JC, Cox L, Burnett M, Turner RC, Hales CN (1992) Diabetologia 35:469-474
8. Blackard WG, Nelson NC (1970) Diabetes 19:302-306
9. Khaksa G, Nalini K, Bhat M, Udupa N (1998) Anal Biochem 260:92-95
10. Shenoy DB, D'Souza RJ, Tiwari SB, Udupa N (2003) Drug Dev Ind Pharm 29:555-563
11. Reto S, Lan V, Laszlo V, Fabrice C, Alistair KD, Robin OE, Keith R (1997) Diabetes 46:44-50
12. Moslemi P, Najafabadi AR, Tajerzadeh HJ (2003) Pharm Biomed Anal 33:45-51