Recent advances in understanding the unfolded protein response

Antioxidants and Redox Signaling

Volumn 9, Issue 12, 2007, Pages 2241-2244

  Schröder, Martin ^a   Kohno, Kenji ^b  

^a DURHAM UNIVERSITY   (United Kingdom)

^b NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EDITORIAL; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN FOLDING; SIGNAL TRANSDUCTION;

ANIMALS; CELL NUCLEUS; ENDOPLASMIC RETICULUM; HUMANS; PROTEIN DENATURATION; PROTEINS; SIGNAL TRANSDUCTION;

EID: 35848946806     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2007.1877     Document Type: Editorial

References (37)

1. Back SH, Lee K, Vink E, and Kaufman RJ. Cytoplasmic IRE1α-mediated XBP1 mRNA splicing in the absence of nuclear processing and ER stress. J Biol Chem 281: 18691-18706, 2006.
2. Bailey D and O'Hare P. Transmembrane bZIP transcription factors in ER stress signaling and the unfolded protein response. Antioxid Redox Signal 9: 2305-2321, 2007.
3. 1-42 induces mild endoplasmic reticulum stress in an aggregation state-dependent manner. Antioxid Redox Signal 9: 2245-2254, 2007.
4. Clark MW and Abelson J. The subnuclear localization of tRNA ligase in yeast. J Cell Biol 105: 1515-1526, 1987.
5. Fonseca SG, Lipson KL, and Urano F. Endoplasmic reticulum stress signaling in pancreatic β-cells. Antioxid Redox Signal 9: 2335-2344, 2007.
6. Gonzalez TN, Sidrauski C, Dörfler S, and Walter P. Mechanism of non-spliceosomal mRNA splicing in the unfolded protein response pathway. EMBO J 18: 3119-3132, 1999.
7. Harding HP, Zeng H, Zhang Y, Jungries R, Chung P, Plesken H, Sabatini DD, and Ron D. Diabetes mellitus and exocrine pancreatic dysfunction in Perk-/- mice reveals a role for translational control in secretory cell survival. Mol Cell 7: 1153-1163, 2001.
8. Harding HP, Zhang Y, and Ron D. Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 397: 271-274, 1999.
9. Haynes CM, Titus EA, and Cooper AA. Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death. Mol Cell 15: 767-776, 2004.
10. He CH, Gong P, Hu B, Stewart D, Choi ME, Choi AM, and Alam J. Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation. J Biol Chem 276: 20858-20865, 2001.
11. Hetz CA. ER stress signaling and the BCL-2 family of proteins: from adaptation to irreversible cellular damage. Antioxid Redox Signal, 9: 2345-2355, 2007.
12. Hollien J and Weissman JS. Decay of endoplasmic reticulum-localized mRNAS during the unfolded protein response. Science 313: 104-107, 2006.
13. Hoozemans JJM, Veerhuis R, Van Haastert ES, Rozemuller JM, Baas F, Eikelenboom P, and Scheper W. The unfolded protein response is activated in Alzheimer's disease. Acta Neuropathol (Berl) 110: 165-172, 2005.
14. Huh WK, Falvo JV, Gerke LC, Carroll AS, Howson RW, Weissman JS, and O'Shea EK. Global analysis of protein localization in budding yeast. Nature 425: 686-691, 2003.
15. Kim-Han JS and O'Malley KL. Cell stress induced by the parkinsonian mimetic, 6-hydroxydopamine, is concurrent with oxidation of the chaperone, ERp57, and aggresome formation. Antioxid Redox Signal 9: 2255-2264, 2007.
16. Kincaid MM and Cooper AA. ERADicate ER stress or die trying. Antioxid Redox Signal 9: 2373-2387, 2007.
17. Kohno K. How transmembrane proteins sense endoplasmic reticulum stress. Antioxid Redox Signal 9: 2295-2303, 2007.
18. Laski FA, Fire AZ, Rajbhandary UL, and Sharp PA. Characterization of tRNA precursor splicing in mammalian extracts. J Biol Chem 258: 11974-11980, 1983.
19. Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, Okada T, Yoshida H, Mori K, and Kaufman RJ. IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev 16: 452-466, 2002.
20. Malhotra JD and Kaufman RJ. Endoplasmic reticulum stress and oxidative stress: A vicious cycle or a double-edged sword? Antioxid Redox Signal, 9: 2277-2293, 2007.
21. Meredith SC. Protein denaturation and aggregation: Cellular responses to denatured and aggregated proteins. Ann N Y Acad Sci 1066: 181-221, 2005.
22. Oyadomari S, Yun C, Fisher EA, Kreglinger N, Kreibich G, Oyadomari M, Harding HP, Goodman AG, Harant H, Garrison JL, Taunton J, Katze MG, and Ron D. Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload. Cell 126: 727-739, 2006.
23. Özcan U, Cao Q, Yilmaz E, Lee A-H, Iwakoshi NN, Ozdelen E, Tuncman G, Görgün C, Glimcher LH, and Hotamisligil GS. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306: 457-461, 2004.
24. Roberts GG, Di Loreto MJ, Marshall M, Wang J, and Degracia DJ. Hippocampal cellular stress responses after global brain ischemia and reperfusion. Antioxid Redox Signal 9: 2265-2275, 2007.
25. Rüegsegger U, Leber JH, and Walter P. Block Of HAC1 mRNA translation by long-range base pairing is released by cytoplasmic splicing upon induction of the unfolded protein response. Cell 107: 103-114, 2001.
26. Scheuner D, Song B, Mcewen E, Liu C, Laybutt R, Gillespie P, Saunders T, Bonner-Weir S, and Kaufman RJ. Translational control is required for the unfolded protein response and in vivo glucose homeostasis. Mol Cell 7: 1165-1176, 2001.
27. Schröder M, Chang JS, and Kaufman RJ. The unfolded protein response represses nitrogen-starvation induced developmental differentiation in yeast. Genes Dev 14: 2962-2975, 2000.
28. Schröder M, Clark R, Liu CY, and Kaufman RJ. The unfolded protein response represses differentiation through the RPD3-SIN3 histone deacetylase. EMBO J 23: 2281-2292, 2004.
29. Tu BP and Weissman JS. Oxidative protein folding in eukaryotes: Mechanisms and consequences. J Cell Biol 164: 341-346, 2004.
30. Unterberger U, Hoftberger R, Gelpi E, Flicker H, Budka H, and Voigtlander T. Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo. J Neuropathol Exp Neurol 65: 348-357, 2006.
31. Wek RC and Cavener DR. Translational control and the unfolded protein response. Antioxid Redox Signal 9: 2357-2371, 2007.
32. Xu C, Bailly-Maitre B, and Reed JC. Endoplasmic reticulum stress: Cell life and death decisions. J Clin Invest 115: 2656-2664, 2005.
33. Ye J, Rawson RB, Komuro R, Chen X, Dave UP, Prywes R, Brown MS, and Goldstein JL. ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol Cell 6: 1355-1364, 2000.
34. Yoshida H. Unconventional splicing of XBP-1 mRNA in the unfolded protein response. Antioxid Redox Signal 9: 2323-2333, 2007.
35. Yoshida H, Matsui T, Hosokawa N, Kaufman RJ, Nagata K, and Mori K. A Time-dependent phase shift in the mammalian unfolded protein response. Dev Cell 4: 265-271, 2003.
36. Yoshihisa T, Yunoki-Esaki K, Ohshima C, Tanaka N, and Endo T. Possibility of cytoplasmic pre-tRNA splicing: the yeast tRNA splicing endonuclease mainly localizes on the mitochondria. Mol Biol Cell 14: 3266-3279, 2003.
37. Zillmann M, Gorovsky MA, and Phizicky EM. Conserved mechanism of tRNA splicing in eukaryotes. Mol Cell Biol 11: 5410-5416, 1991.