-
1
-
-
0034175876
-
Apoptotic mechanisms in acute renal failure
-
Ueda N, Kaushal GP, Shah SV. Apoptotic mechanisms in acute renal failure. Am J Med 2000; 108:403-15.
-
(2000)
Am J Med
, vol.108
, pp. 403-415
-
-
Ueda, N.1
Kaushal, G.P.2
Shah, S.V.3
-
2
-
-
0029821680
-
Mechanisms of apoptosis and its potential role in renal tubular epithelial cell injury
-
Lieberthal W, Levine JS. Mechanisms of apoptosis and its potential role in renal tubular epithelial cell injury. Am J Physiol 1996; 271:F477-88.
-
(1996)
Am J Physiol
, vol.271
-
-
Lieberthal, W.1
Levine, J.S.2
-
3
-
-
0034894967
-
A novel model of ischemia in renal tubular cells which closely parallels in vivo injury
-
Meldrum KK, Meldrum DR, Hile KL, Burnett AL, Harken AH. A novel model of ischemia in renal tubular cells which closely parallels in vivo injury. J Surg Res 2001; 99:288-93, 2001.
-
(2001)
J Surg Res 2001
, vol.99
, pp. 288-293
-
-
Meldrum, K.K.1
Meldrum, D.R.2
Hile, K.L.3
Burnett, A.L.4
Harken, A.H.5
-
4
-
-
0036285014
-
Simulated ischemia induces renal tubular cell apoptosis through a nuclear factor-kappaB dependent mechanism
-
Meldrum KK, Hile K, Meldrum DR, Crone JA, Gearhart JP, Burnett AL. Simulated ischemia induces renal tubular cell apoptosis through a nuclear factor-kappaB dependent mechanism. J Urol 2002; 168:248-52.
-
(2002)
J Urol
, vol.168
, pp. 248-252
-
-
Meldrum, K.K.1
Hile, K.2
Meldrum, D.R.3
Crone, J.A.4
Gearhart, J.P.5
Burnett, A.L.6
-
5
-
-
0037458926
-
Liposomal delivery of heat shock protein 72 into renal tubular cells blocks nuclear factor-kappaB activation, tumor necrosis factor-alpha production, and subsequent ischemia-induced apoptosis
-
Meldrum KK, Burnett AL, Meng X, Misseri R, Shaw MB, Gearhart JP, Meldrum DR. Liposomal delivery of heat shock protein 72 into renal tubular cells blocks nuclear factor-kappaB activation, tumor necrosis factor-alpha production, and subsequent ischemia-induced apoptosis. Circ Res 2003; 92:293-9.
-
(2003)
Circ Res
, vol.92
, pp. 293-299
-
-
Meldrum, K.K.1
Burnett, A.L.2
Meng, X.3
Misseri, R.4
Shaw, M.B.5
Gearhart, J.P.6
Meldrum, D.R.7
-
6
-
-
0032411879
-
Stress signals for apoptosis: Ceramide and c-Jun kinase
-
Basu S, Kolesnick R. Stress signals for apoptosis: Ceramide and c-Jun kinase. Oncogene 1998; 17:3277-85.
-
(1998)
Oncogene
, vol.17
, pp. 3277-3285
-
-
Basu, S.1
Kolesnick, R.2
-
7
-
-
0030448021
-
Functions of ceramide in coordinating cellular responses to stress
-
Hannun YA. Functions of ceramide in coordinating cellular responses to stress. Science 1996; 274:1855-9.
-
(1996)
Science
, vol.274
, pp. 1855-1859
-
-
Hannun, Y.A.1
-
8
-
-
0031439924
-
Coordinate regulation of stress- and mitogen-activated protein kinases in the apoptotic actions of ceramide and sphingosine
-
Jarvis WD, Fornari FA, Auer KL, Freemerman AJ, Szabo E, Birrer MJ, Johnson CR, Barbour SE, Dent P, Grant S. Coordinate regulation of stress- and mitogen-activated protein kinases in the apoptotic actions of ceramide and sphingosine. Mol Pharm 1997; 52:935-47.
-
(1997)
Mol Pharm
, vol.52
, pp. 935-947
-
-
Jarvis, W.D.1
Fornari, F.A.2
Auer, K.L.3
Freemerman, A.J.4
Szabo, E.5
Birrer, M.J.6
Johnson, C.R.7
Barbour, S.E.8
Dent, P.9
Grant, S.10
-
9
-
-
0030634437
-
Ceramide: A novel lipid mediator of apoptosis
-
Smyth MJ, Obeid LM, Hannun YA. Ceramide: A novel lipid mediator of apoptosis. Adv Pharm 1997; 41:133-54.
-
(1997)
Adv Pharm
, vol.41
, pp. 133-154
-
-
Smyth, M.J.1
Obeid, L.M.2
Hannun, Y.A.3
-
11
-
-
0037418238
-
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
-
Lei K, Davis RJ. JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc Natl Acad Sci USA 2003; 100:2432-7.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 2432-2437
-
-
Lei, K.1
Davis, R.J.2
-
12
-
-
35848951906
-
Ceramide promotes apoptosis in lung cancer derived A549 cells by a mechanism involving JNK
-
Kurinna SM, Tsao CC, Nica AF, Jiffar T, Ruvolo PP. Ceramide promotes apoptosis in lung cancer derived A549 cells by a mechanism involving JNK. Cancer Research 2004; 64:7582-6.
-
(2004)
Cancer Research
, vol.64
, pp. 7582-7586
-
-
Kurinna, S.M.1
Tsao, C.C.2
Nica, A.F.3
Jiffar, T.4
Ruvolo, P.P.5
-
13
-
-
0030755466
-
Tissue-specific pattern of stress kinase activation in ischemic/reperfused heart and kidney
-
Yin T, Sandhu G, Wolfgang CD, Burrier A, Webb RL, Rigel DF, Hai T, Whelan J. Tissue-specific pattern of stress kinase activation in ischemic/reperfused heart and kidney. J Biol Chem 1997; 272:19943-50.
-
(1997)
J Biol Chem
, vol.272
, pp. 19943-19950
-
-
Yin, T.1
Sandhu, G.2
Wolfgang, C.D.3
Burrier, A.4
Webb, R.L.5
Rigel, D.F.6
Hai, T.7
Whelan, J.8
-
14
-
-
0027143725
-
Protein serine/threonine phosphatases: Structure, regulation, and functions in cell growth
-
Mumby MC, Walter G. Protein serine/threonine phosphatases: Structure, regulation, and functions in cell growth. Physiological Reviews 1993; 73:673-99.
-
(1993)
Physiological Reviews
, vol.73
, pp. 673-699
-
-
Mumby, M.C.1
Walter, G.2
-
15
-
-
0034882639
-
Ceramide regulates cellular homeostasis via diverse stress signaling pathways
-
Ruvolo PP. Ceramide regulates cellular homeostasis via diverse stress signaling pathways. Leukemia 2001; 15:1153-60.
-
(2001)
Leukemia
, vol.15
, pp. 1153-1160
-
-
Ruvolo, P.P.1
-
16
-
-
0037401894
-
Intracellular signal transduction pathways activated by ceramide and its metabolites
-
Ruvolo PP. Intracellular signal transduction pathways activated by ceramide and its metabolites. Pharmacol Res 2003; 47:383-92.
-
(2003)
Pharmacol Res
, vol.47
, pp. 383-392
-
-
Ruvolo, P.P.1
-
17
-
-
0027055504
-
Molecular cloning and developmental expression of the catalytic and 65-kDa regulatory subunits of protein phosphatase 2A in Drosophila
-
Mayer-Jaekel RE, Baumgartner S, Bilbe G, Ohkura H, Glover DM, Hemmings BA. Molecular cloning and developmental expression of the catalytic and 65-kDa regulatory subunits of protein phosphatase 2A in Drosophila. Mol Biol Cell 1992; 3:287-98.
-
(1992)
Mol Biol Cell
, vol.3
, pp. 287-298
-
-
Mayer-Jaekel, R.E.1
Baumgartner, S.2
Bilbe, G.3
Ohkura, H.4
Glover, D.M.5
Hemmings, B.A.6
-
18
-
-
0030047451
-
High complexity in the expression of the B' subunit of protein phosphatase 2A0: Evidence for the existence of at least seven novel isoforms
-
Csortos C, Zolnierowicz S, Bako E, Durbin SD, DePaoli-Roach AA. High complexity in the expression of the B' subunit of protein phosphatase 2A0: Evidence for the existence of at least seven novel isoforms. J Biol Chem 1996; 271:2578-88.
-
(1996)
J Biol Chem
, vol.271
, pp. 2578-2588
-
-
Csortos, C.1
Zolnierowicz, S.2
Bako, E.3
Durbin, S.D.4
DePaoli-Roach, A.A.5
-
19
-
-
0025881195
-
Structure of the 55-kDa regulatory subunit of protein phosphatase 2A: Evidence for a neuronal-specific isoform
-
Mayer RE, Hendrix P, Cron P, Matthies R, Stone SR, Goris J, Merlevede W, Hofsteenge J, Hemmings BA. Structure of the 55-kDa regulatory subunit of protein phosphatase 2A: Evidence for a neuronal-specific isoform. Biochemistry 1991; 30:3589 -97.
-
(1991)
Biochemistry
, vol.30
, pp. 3589-3597
-
-
Mayer, R.E.1
Hendrix, P.2
Cron, P.3
Matthies, R.4
Stone, S.R.5
Goris, J.6
Merlevede, W.7
Hofsteenge, J.8
Hemmings, B.A.9
-
20
-
-
0028832251
-
Identification of a new family of protein phosphatase 2A regulatory subunits
-
McCright B, Virshup DM. Identification of a new family of protein phosphatase 2A regulatory subunits. J Biol Chem 1995; 270:26123-8.
-
(1995)
J Biol Chem
, vol.270
, pp. 26123-26128
-
-
McCright, B.1
Virshup, D.M.2
-
21
-
-
0025895590
-
Constant expression and activity of protein phosphatase 2A in synchronized cells
-
Ruediger R, Van Wart Hood JE, Mumby M, Walter G. Constant expression and activity of protein phosphatase 2A in synchronized cells. Mol Cell Bio 1991; 11:4282-5.
-
(1991)
Mol Cell Bio
, vol.11
, pp. 4282-4285
-
-
Ruediger, R.1
Van Wart Hood, J.E.2
Mumby, M.3
Walter, G.4
-
22
-
-
0028276611
-
Different oligomeric forms of protein phosphatase 2A activate and inhibit simian virus 40 DNA replication
-
Cegielska A, Shaffer S, Derua R, Goris J, Virshup DM. Different oligomeric forms of protein phosphatase 2A activate and inhibit simian virus 40 DNA replication. Mol Cell Biol 1994; 14:4616-23.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 4616-4623
-
-
Cegielska, A.1
Shaffer, S.2
Derua, R.3
Goris, J.4
Virshup, D.M.5
-
23
-
-
0028924295
-
A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle
-
Sontag E, Nunbhakdi-Craig V, Bloom GS, Mumby MC. A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle. J Cell Biol 1995; 128:1131-44.
-
(1995)
J Cell Biol
, vol.128
, pp. 1131-1144
-
-
Sontag, E.1
Nunbhakdi-Craig, V.2
Bloom, G.S.3
Mumby, M.C.4
-
24
-
-
0029834655
-
The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm
-
McCright B, Rivers AM, Audlin S, Virshup DM. The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm. J Biol Chem 1996; 271:22081-9.
-
(1996)
J Biol Chem
, vol.271
, pp. 22081-22089
-
-
McCright, B.1
Rivers, A.M.2
Audlin, S.3
Virshup, D.M.4
-
25
-
-
0033575320
-
Ceramide induces Bcl2 dephosphorylation via a mechanism involving mitochondrial PP2A
-
Ruvolo PP, Deng X, Ito T, Carr BK, May WS. Ceramide induces Bcl2 dephosphorylation via a mechanism involving mitochondrial PP2A. J Biol Chem 1999; 274:20296-300.
-
(1999)
J Biol Chem
, vol.274
, pp. 20296-20300
-
-
Ruvolo, P.P.1
Deng, X.2
Ito, T.3
Carr, B.K.4
May, W.S.5
-
26
-
-
0037151038
-
A functional role for the B56 alpha-subunit of protein phosphatase 2A in ceramide-mediated regulation of Bcl2 phosphorylation status and function
-
Ruvolo PP, Clark W, Mumby M, Gao F, May WS. A functional role for the B56 alpha-subunit of protein phosphatase 2A in ceramide-mediated regulation of Bcl2 phosphorylation status and function. J Biol Chem 2002; 277:22847-52.
-
(2002)
J Biol Chem
, vol.277
, pp. 22847-22852
-
-
Ruvolo, P.P.1
Clark, W.2
Mumby, M.3
Gao, F.4
May, W.S.5
-
27
-
-
0031281529
-
Comparison of in vitro preconditioning responses of isolated pig and rabbit cardiomyocytes: Effects of a protein phosphatase inhibitor, fostriecin
-
Armstrong SC, Kao R, Gao W, Shivell LC, Downey JM, Honkanen RE, Ganote CE. Comparison of in vitro preconditioning responses of isolated pig and rabbit cardiomyocytes: Effects of a protein phosphatase inhibitor, fostriecin. J Mol Cell Cardiol 1997; 29:3009-24.
-
(1997)
J Mol Cell Cardiol
, vol.29
, pp. 3009-3024
-
-
Armstrong, S.C.1
Kao, R.2
Gao, W.3
Shivell, L.C.4
Downey, J.M.5
Honkanen, R.E.6
Ganote, C.E.7
-
28
-
-
0031893644
-
Protein phosphatase inhibitors calyculin A and fostriecin protect rabbit cardiomyocytes in late ischemia
-
Armstrong SC, Gao W, Lane JR, Ganote CE. Protein phosphatase inhibitors calyculin A and fostriecin protect rabbit cardiomyocytes in late ischemia. J Mol Cell Cardiol 1998; 30:61-73.
-
(1998)
J Mol Cell Cardiol
, vol.30
, pp. 61-73
-
-
Armstrong, S.C.1
Gao, W.2
Lane, J.R.3
Ganote, C.E.4
-
29
-
-
0037009005
-
Protein phosphatase 2A associates with and regulates atypical PKC and the epithelial tight junction complex
-
Nunbhakdi-Craig V, Machleidt T, Ogris E, Bellotto D, White CL, Sontag E. Protein phosphatase 2A associates with and regulates atypical PKC and the epithelial tight junction complex. J Cell Biol 2002; 158:967-78.
-
(2002)
J Cell Biol
, vol.158
, pp. 967-978
-
-
Nunbhakdi-Craig, V.1
Machleidt, T.2
Ogris, E.3
Bellotto, D.4
White, C.L.5
Sontag, E.6
-
30
-
-
0030848745
-
Expression of bcl-2 and bax in regenerating rat renal tubules following ischemic injury
-
Basile DP, Liapis H, Hammerman MR. Expression of bcl-2 and bax in regenerating rat renal tubules following ischemic injury. Am J Physiol 1997; 272:F640-7.
-
(1997)
Am J Physiol
, vol.272
-
-
Basile, D.P.1
Liapis, H.2
Hammerman, M.R.3
-
31
-
-
0038702246
-
Phosphatases in apoptosis: To be or not to be, PP2A is in the heart of the question
-
Van Hoof C, Goris J. Phosphatases in apoptosis: To be or not to be, PP2A is in the heart of the question. Biochim Biophys Acta 2003; 1640:97-104.
-
(2003)
Biochim Biophys Acta
, vol.1640
, pp. 97-104
-
-
Van Hoof, C.1
Goris, J.2
-
32
-
-
0028593362
-
Characterization of a renal epithelial cell model of apoptosis using okadaic acid and the NRK-52E cell line
-
Davis MA, Smith MW, Chang SH, Trump BF. Characterization of a renal epithelial cell model of apoptosis using okadaic acid and the NRK-52E cell line. Toxicol Pathol 1994; 22:595-605.
-
(1994)
Toxicol Pathol
, vol.22
, pp. 595-605
-
-
Davis, M.A.1
Smith, M.W.2
Chang, S.H.3
Trump, B.F.4
-
33
-
-
0030297475
-
Differential sensitivity of normal and H-ras oncogene-transformed rat kidney epithelial cells to okadaic acid-induced apoptosis
-
Davis MA, Chang SH, Trump BF. Differential sensitivity of normal and H-ras oncogene-transformed rat kidney epithelial cells to okadaic acid-induced apoptosis. Toxicol Appl Pharmacol 1996; 141:93-101.
-
(1996)
Toxicol Appl Pharmacol
, vol.141
, pp. 93-101
-
-
Davis, M.A.1
Chang, S.H.2
Trump, B.F.3
-
34
-
-
0037007096
-
Actions of PP2A on the MAP kinase pathway and apoptosis are mediated by distinct regulatory subunits
-
Silverstein AM, Barrow CA, Davis AJ, Mumby MC. Actions of PP2A on the MAP kinase pathway and apoptosis are mediated by distinct regulatory subunits. Proc Natl Acad Sci USA 2002; 99:4221-6.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 4221-4226
-
-
Silverstein, A.M.1
Barrow, C.A.2
Davis, A.J.3
Mumby, M.C.4
-
35
-
-
9144223779
-
Critical role for protein phosphatase 2A heterotrimers in mammalian cell survival
-
Strack S, Cribbs JT, Gomez L. Critical role for protein phosphatase 2A heterotrimers in mammalian cell survival. J Biol Chem 2004; 279:47732-9.
-
(2004)
J Biol Chem
, vol.279
, pp. 47732-47739
-
-
Strack, S.1
Cribbs, J.T.2
Gomez, L.3
-
36
-
-
0036096778
-
B56-associated protein phosphatase 2A is required for survival and protects from apoptosis in Drosophila melanogaster
-
Li X, Scuderi A, Letsou A, Virshup DM. B56-associated protein phosphatase 2A is required for survival and protects from apoptosis in Drosophila melanogaster. Mol Cell Biol 2002; 22:3674-84.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3674-3684
-
-
Li, X.1
Scuderi, A.2
Letsou, A.3
Virshup, D.M.4
-
37
-
-
1542503811
-
PKC α mediates chemoresistance in acute lymphoblastic leukemia through effects on Bcl2 phosphorylation
-
Jiffar T, Kurinna S, Suck G, Carison-Brener D, Ricciardi MR, Konopleva M, Andreeff M, Ruvolo PP. PKC α mediates chemoresistance in acute lymphoblastic leukemia through effects on Bcl2 phosphorylation. Leukemia 2004; 18:505-12.
-
(2004)
Leukemia
, vol.18
, pp. 505-512
-
-
Jiffar, T.1
Kurinna, S.2
Suck, G.3
Carison-Brener, D.4
Ricciardi, M.R.5
Konopleva, M.6
Andreeff, M.7
Ruvolo, P.P.8
-
38
-
-
0030842898
-
Altered ceramide and sphingosine expression during the induction phase of ischemic acute renal failure
-
Zager RA, Iwata M, Conrad DS, Burkhart KM, Igarashi Y. Altered ceramide and sphingosine expression during the induction phase of ischemic acute renal failure. Kidney Int 1997; 52:60-70.
-
(1997)
Kidney Int
, vol.52
, pp. 60-70
-
-
Zager, R.A.1
Iwata, M.2
Conrad, D.S.3
Burkhart, K.M.4
Igarashi, Y.5
-
39
-
-
0141726861
-
Induction of apoptosis in cultured human proximal tubule cells by fumonisins and fumonisin metabolites
-
Seefelder W, Humpf HU, Schwerdt G, Freudinger R, Gekle M. Induction of apoptosis in cultured human proximal tubule cells by fumonisins and fumonisin metabolites. Toxicol Appl Pharmacol 2003; 192:146-53.
-
(2003)
Toxicol Appl Pharmacol
, vol.192
, pp. 146-153
-
-
Seefelder, W.1
Humpf, H.U.2
Schwerdt, G.3
Freudinger, R.4
Gekle, M.5
-
40
-
-
0029056908
-
Sphingosine: A mediator of acute renal tubular injury and subsequent cytoresistance
-
Iwata M, Herrington J, Zager RA. Sphingosine: A mediator of acute renal tubular injury and subsequent cytoresistance. Proc Natl Acad Sci USA 1995; 92:8970-4.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8970-8974
-
-
Iwata, M.1
Herrington, J.2
Zager, R.A.3
-
41
-
-
0037066756
-
Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide in the A549 human lung adenocarcinoma cell line: Role for endogenous ceramide in mediating the action of exogenous ceramide
-
Ogretmen B, Pettus BJ, Rossi MJ, Wood R, Usta J, Szulc Z, Bielawska A, Obeid LM, Hannun YA. Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide in the A549 human lung adenocarcinoma cell line: Role for endogenous ceramide in mediating the action of exogenous ceramide. J Biol Chem 2002; 277:12960-9.
-
(2002)
J Biol Chem
, vol.277
, pp. 12960-12969
-
-
Ogretmen, B.1
Pettus, B.J.2
Rossi, M.J.3
Wood, R.4
Usta, J.5
Szulc, Z.6
Bielawska, A.7
Obeid, L.M.8
Hannun, Y.A.9
-
42
-
-
0032739599
-
Renal cortical ceramide patterns during ischemic and toxic injury: Assessments by HPLC-mass spectrometry
-
Kalhorn T, Zager RA. Renal cortical ceramide patterns during ischemic and toxic injury: Assessments by HPLC-mass spectrometry. Am J Physiol 1999; 277:F723-33.
-
(1999)
Am J Physiol
, vol.277
-
-
Kalhorn, T.1
Zager, R.A.2
-
43
-
-
0032696035
-
Mass spectrometric identification of increased C16 ceramide levels during apoptosis
-
Thomas RL, Matsko CM, Lotze MT, Amoscato AA. Mass spectrometric identification of increased C16 ceramide levels during apoptosis. J Biol Chem 1999; 274:30580-8.
-
(1999)
J Biol Chem
, vol.274
, pp. 30580-30588
-
-
Thomas, R.L.1
Matsko, C.M.2
Lotze, M.T.3
Amoscato, A.A.4
-
44
-
-
7444233154
-
The PP2A-associated protein alpha4 is an essential inhibitor of apoptosis
-
Kong M, Fox CJ, Mu J, Solt L, Xu A, Cinalli RM, Birnbaum MJ, Lindsten T, Thompson CB. The PP2A-associated protein alpha4 is an essential inhibitor of apoptosis. Science 2004; 306:695-8.
-
(2004)
Science
, vol.306
, pp. 695-698
-
-
Kong, M.1
Fox, C.J.2
Mu, J.3
Solt, L.4
Xu, A.5
Cinalli, R.M.6
Birnbaum, M.J.7
Lindsten, T.8
Thompson, C.B.9
|