Thermotherapy of Prostate Cancer Using Magnetic Nanoparticles: Feasibility, Imaging, and Three-Dimensional Temperature Distribution

European Urology

Volumn 52, Issue 6, 2007, Pages 1653-1662

  Johannsen, Manfred ^a   Gneveckow, Uwe ^b   Thiesen, Burghard ^a   Taymoorian, Kasra ^a   Cho, Chie Hee ^a   Waldöfner, Norbert ^b   Scholz, Regina ^b   Jordan, Andreas ^b   Loening, Stefan A ^a   Wust, Peter ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b MagForce Nanotechnologies AG   (Germany)

Author keywords

Magnetic; Nanoparticles; Prostate cancer; Thermotherapy

Indexed keywords

IRON OXIDE; NANOPARTICLE;

ARTICLE; BIOCOMPATIBILITY; CANCER RECURRENCE; CLINICAL ARTICLE; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; DOSIMETRY; HUMAN; HYPERTHERMIC THERAPY; MAGNETIC FIELD; MALE; NON INVASIVE MEASUREMENT; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; PROSTATE CANCER; RECTUM TEMPERATURE;

HUMANS; HYPERTHERMIA, INDUCED; IMAGING, THREE-DIMENSIONAL; MAGNETICS; MALE; NANOPARTICLES; PROSPECTIVE STUDIES; PROSTATIC NEOPLASMS; TEMPERATURE; TOMOGRAPHY, X-RAY COMPUTED;

EID: 35748979689     PISSN: 03022838     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eururo.2006.11.023     Document Type: Article

References (30)

1. Hildebrandt B., Wust P., Ahlers O., et al. The cellular and molecular basis of hyperthermia. Crit Rev Oncol Hematol 43 (2002) 33-56
2. Jordan A., Maier-Hauff K., Wust P., and Johannsen M. Nanoparticles for thermotherapy. In: Kumar C.S.S.R. (Ed). Nanomaterials for cancer therapy (2006), Wiley-VCH, Weinheim 242-258
3. Jordan A., Wust P., Fähling H., John W., Hinz A., and Felix R. Inductive heating of ferrimagnetic particles and magnetic fluids: physical evaluation of their potential for hyperthermia. Int J Hyperthermia 9 (1993) 51-68
4. Jordan A., Wust P., Scholz R., et al. Effects of magnetic fluid hyperthermia (MFH) on C3H mammary carcinoma in vivo. Int J Hyperthermia 13 (1997) 587-605
5. Jordan A., Scholz R., Maier-Hauff K., et al. The effect of thermotherapy using magnetic nanoparticles on rat malignant glioma. J Neurooncol 78 (2006) 7-14
6. Johannsen M., Jordan A., Scholz R., et al. Evaluation of magnetic fluid hyperthermia in a standard rat model of prostate cancer. J Endourol 18 (2004) 495-500
7. Johannsen M., Thiesen B., Jordan A., et al. Magnetic fluid hyperthermia (MFH) reduces prostate cancer growth in the orthotopic Dunning R3327 rat model. Prostate 64 (2005) 283-292
8. Johannsen M., Thiesen B., Gneveckow U., et al. Thermotherapy using magnetic nanoparticles combined with external radiation in an orthotopic rat model of prostate cancer. Prostate 66 (2006) 97-104
9. Aus G., Abbou C.C., Bolla M., et al. EAU guidelines on prostate cancer. Eur Urol 48 (2005) 546-551
10. Touma N.J., Izawa J.I., and Chin J.L. Current status of local salvage therapies following radiation failure for prostate cancer. J Urol 173 (2005) 373-379
11. Gneveckow U., Jordan A., Scholz R., et al. Description and characterization of the novel hyperthermia- and thermoablation-system MFH 300F for clinical magnetic fluid hyperthermia. Med Phys 31 (2004) 1444-1451
12. Johannsen M., Gneveckow U., Eckelt L., et al. Clinical hyperthermia of prostate cancer using magnetic nanoparticles: presentation of a new interstitial technique. Int J Hyperthermia 21 (2005) 637-647
13. Sapareto S.A., and Dewey W.C. Thermal dose determination in cancer therapy. Int J Radiat Oncol Biol Phys 10 (1984) 787-800
14. Jones E.L., Oleson J.R., Prosnitz L.R., et al. Randomized trial of hyperthermia and radiation for superficial tumors. J Clin Oncol 23 (2005) 3079-3085
15. Thrall D.E., LaRue S.M., Yu D., et al. Thermal dose is related to duration of local control in canine sarcomas treated with thermoradiotherapy. Clin Cancer Res 11 (2005) 5206-5214
16. Jones E., Thrall D., Dewhirst M.W., and Vujaskovic Z. Prospective thermal dosimetry: the key to hyperthermia's future. Int J Hyperthermia 22 (2006) 247-253
17. Van der Zee J., Peer-Valstar J.N., Rietveld P.J., de Graaf-Strukowska I., and van Rhoon C. Practical limitations of interstitial thermometry during deep hyperthermia. Int J Radiat Oncol Biol Phys 40 (1998) 1205-1212
18. Wust P., Cho C.H., Hildebrandt B., and Gellermann J. Thermal monitoring: invasive, minimal-invasive and non-invasive approaches. Int J Hyperthermia 22 (2006) 255-262
19. Van Vulpen M., Raaymakers B.W., Lagendijk J.J., et al. Three-dimensional controlled interstitial hyperthermia combined with radiotherapy for locally advanced prostate carcinoma-a feasibility study. Int J Radiat Oncol Biol Phys 53 (2002) 116-126
20. Van Vulpen M., De Leeuw A.A.C., Van de Kamer J.B., et al. Comparison of intra-luminal versus intratumoral temperature measurements in patients with locally advanced prostate cancer treated with the coaxial TEM system: report of a feasibility study. Int J Hyperthermia 19 (2003) 481-497
21. Tilly W., Wust P., Rau B., et al. Temperature data and specific absorption rates in pelvic tumours: predictive factors and correlations. Int J Hyperthermia 17 (2001) 172-188
22. Raaymakers B.W., Van Vulpen M., Lagendijk J.J., De Leeuw A.A.C., Crezee J., and Battermann J.J. Determination and validation of the actual 3D temperature distribution during interstitial hyperthermia of prostate carcinoma. Phys Med Biol 46 (2001) 3115-3131
23. Tilly W., Gellermann J., Graf R., et al. Regional hyperthermia in conjunction with definitive radiotherapy against recurrent or locally advanced prostate cancer T3 pN0 M0. Strahlenther Onkol 181 (2005) 35-41
24. Wust P., Gneveckow U., Johannsen M., et al. Magnetic nanoparticles for interstitial thermotherapy-feasibility, tolerance and achieved temperatures. Int J Hyperthermia 22 (2006) 673-685
25. Dewhirst M.W., Sim D.A., Sapareto S., and Connor W.G. Importance of minimum tumor temperature in determining early and long term response of spontaneous canine and feline tumors to heat and radiation. Cancer Res 44 (1984) 43-50
26. Thrall D.E., Rosner G.L., Azuma C., et al. Using units of CEM 43 °C T90, local hyperthermia thermal dose can be delivered as prescribed. Int J Hyperthermia 16 (2000) 415-428
27. Van Vulpen M., De Leeuw A.A., Raaymakers B.W., et al. Radiotherapy and hyperthermia in the treatment of patients with locally advanced prostate cancer: preliminary results. BJU Int 93 (2004) 36-41
28. Anscher M.S., Samulski T.V., Dodge R., Prosnitz L.R., and Dewhirst M.W. Combined external beam irradiation and external regional hyperthermia for locally advanced adenocarcinoma of the prostate. Int J Radiat Oncol Biol Phys 37 (1997) 1059-1065
29. Hurwitz M.D., Kaplan I.D., Hansen J.L., et al. Hyperthermia combined with radiation in treatment of locally advanced prostate cancer is associated with a favourable toxicity profile. Int J Hyperthermia 21 (2005) 649-656
30. Oleson J.R., Samulski T.V., Leopold K.A., et al. Sensitivity of hyperthermia trial outcomes to temperature and time: Implications for thermal goals of treatment. Int J Radiat Oncol Biol Phys 25 (1993) 289-297