Genetic predisposition to chronic obstructive pulmonary disease: Advances in α1-antitrypsin deficiency and the serpinopathies

Clinical Medicine, Journal of the Royal College of Physicians of London

Volumn 7, Issue 5, 2007, Pages 446-447

  Lomas, David A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE INHIBITOR;

ALPHA 1 ANTITRYPSIN DEFICIENCY; CHRONIC OBSTRUCTIVE LUNG DISEASE; ENDOPLASMIC RETICULUM; GENETIC PREDISPOSITION; HEREDITY; HUMAN; SHORT SURVEY;

EID: 35748972348     PISSN: 14702118     EISSN: None     Source Type: Journal    
DOI: 10.7861/clinmedicine.7-5-446     Document Type: Short Survey

References (10)

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4. 1-antitrypsin Z in the endoplasmic reticulum activates caspases-4 and -12, NFkappaB, and BAP31 but not the unfolded protein response. J Biol Chem 2005;280:39002-15.
5. 1- antitrypsin deficient children. Acta Paed Scand 1988;77:847-51.
6. 1- antitrypsin related emphysema. Am J Respir Cell Mol Biol 1998;18:670-4.
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9. 1-antitrypsin co-localise with neutrophils in emphysematous alveoli and are chemotactic in vivo. Am J Pathol 2005;166:377-86.
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