1,4-Dihydropyridines (DHPs) - A class of very potent drugs: Syntheses of isotopically labeled DHP derivatives during the last four decades

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 50, Issue 9-10, 2007, Pages 818-830

  Pleiss, U ^a  

^a BAYER PHARMA AG   (Germany)

Author keywords

Calcium antagonist; Carbon 11; Carbon 13; Carbon 14; Deuterium; Dihydropyridine; Iodine 125; Tritium

Indexed keywords

CALCIUM; CARBON; DISEASES; IODINE; PYRIDINE; TRITIUM;

CALCIUM ANTAGONIST; CARBON 14; CARBON-11; CARBON-13; DIHYDROPYRIDINES; DRUG SYNTHESIS; IODINE-125; ISOTOPICALLY LABELED; LABELINGS; POTENT DRUGS;

DEUTERIUM;

1,4 DIHYDROPYRIDINE DERIVATIVE; AMLODIPINE; CALCIUM ANTAGONIST; CALCIUM CHANNEL BLOCKING AGENT; CARBON 11; CARBON 13; CARBON 14; DEUTERIUM; DIHYDROPYRIDINE DERIVATIVE; FELODIPINE; IODINE 125; ISRADIPINE; MANIDIPINE; NICARDIPINE; NILVADIPINE; NIMODIPINE; NISOLDIPINE; NITRENDIPINE; RADIOISOTOPE; TRITIUM;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CONJUGATION; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ISOTOPE LABELING; POSITRON EMISSION TOMOGRAPHY; REACTION ANALYSIS; STRUCTURE ANALYSIS;

EID: 35748968448     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1418     Document Type: Article

References (49)

1. Hantzsch A. Justus Liebigs Ann Chem 1882; 215: 1-82.
2. Phillipps AP, Randall LD. US 2 359 329. Wellcome, 1943.
3. Bossert F, Vater W. Med Res Rev 1989; 9: 291-324.
4. Bossert F, Vater W. DE 1 493677. Bayer AG, 1964.
5. Bossert F, Vater W. Naturwissenschaften 1971; 58: 578.
6. Love B, Tedeschi RE. US 3 511 847. Smith, Kline and French, 1970.
7. Fleckenstein A, Grün G. Arzneim Forsch 1972; 22: 334-344.
8. Kazda R, Towart R. Br J Pharmacol 1981; 72: 582-583.
9. Kazda S, Garthoff B, Meyer H, Schlossmann K, Stoepel K, Towart R, Vater W, Wehinger E. Arzneim Forsch 1980; 30: 2144-2162.
10. Stoepel K, Heise A, Kazda S. Arzneim Forsch 1981; 31: 2056-2064.
11. Arrowsmith JE, Campbell SF, Cross PE, Stubbs JK. Pharmacologist 1985; 27: 290.
12. Nyborg NCB, Mulvany MJ. J Cardiovasc Pharmacol 1984; 6: 499-505.
13. Hof RP, Scholtysik G, Loutzenhiser R, Vuorela HJ, Neumann P. J Cardiovasc Pharmacol 1984; 6: 399-406.
14. Meguro K, Aizawa M, Sohda T, Kawamatsu Y, Nagaoka A. Chem Pharm Bull 1985; 33: 3787-3797.
15. Takenaka T, Usuda S, Nomura T, Maeno H, Sado T. Arzneim Forsch 1976; 26: 2172-2178.
16. Furuta T, Shibata S, Kodama I, Yamada K. J Cardiovasc Pharmacol 1983; 5: 836-841.
17. Janis RA, Maurer SC, Sarmiento JG, Bolger GT, Triggle DJ. Eur J Pharmacol 1982; 82: 191-194.
18. Holck M, Thorens S, Haeusler G. Eur J Pharmacol 1982; 85: 305-315.
19. Ehlert FJ, Itoga E, Roeske ER, Yamamura HI. Biochem Biophys Res Commun 1982; 104: 937-943.
20. Soldatov NM. Bioorg Chem 1989; 17: 141-158.
21. Shevchenko VP, Myasoedov NF, Soldatov NM, Duburs GJ, Kastron W, Skrastins IP. J Label Compd Radiopharm 1989; 27: 721-730.
22. Parnes H, Huang GT. J Label Compd Radiopharm 1991; 29: 87-93.
23. Pleiss U, Schmitt P. J Label Compd Radiopharm 1991; 29: 1091-1094.
24. Taki M, Kuniyasu A, Nakayama H, Kanaoka Y. Chem Pharm Bull 1991; 39: 1860-1862.
25. Wu D, Wang W. J Label Compd Radiopharm 1996; 39: 105-107.
26. Pleiss U, Rosentreter U, Stoltefuss J, Behner O. In Synthesis and Application of Isotopically Labelled Compounds 1997, Heys JR, Melillo DG (eds). Wiley: New York, 1998; 207-211. ISBN 0-471-97863-9.
27. Duhm B, Maul W, Medenwald H, Patzschke K, Wegner LA. Arzneim Forsch 1972; 22: 42-43.
28. Walkenstein SS, Intoccia AP, Flanagan TL, Hwang B, Flint D, Weinstock J, Villani AJ, Blackburn D, Green H. J Pharm Sci 1973; 62: 580-584.
29. Iwanami, M, Shibanuma T, Fujimoto M, Kawai R, Tamazawa K, Takenaka T, Takahashi K, Murakami M. Chem Pharm Bull. 1979; 27: 1426-1440.
30. Meyer H, Wehinger E, Bessert F, Scherling D. Arzneim Forsch 1983; 33: 106-111.
31. Arima H, Tamazawa K, Takeuchi M. J Label Compd Radiopharm 1987; 25: 161-170.
32. Parnes H, Huang GT, Shelton EJ. J Label Compd Radiopharm 1987; 25: 621-626.
33. Wilkinson DJ. Appl Radiat Isot 1988; 39: 554.
34. Scherling D, Pleiss U. J Label Compd Radiopharm 1988; 25: 1393-1400.
35. Maul W, Scherling D. J Label Compd Radiopharm 1988; 26: 457-463.
36. Scherling D. J Label Compd Radiopharm 1989, 27: 599-603.
37. Demmer A, Andreae S, Thole H, Tümmler B. Eur J Biochem 1999; 264: 800-805.
38. Wilson AA, Dannals RF, Ravert HT, Burns HD, Lever SZ, Wagner HN. J Label Compd Radiopharm 1987; 27: 589-598.
39. Stone-Elander S, Roland P, Halldin C, Schwenner E, Boeshagen H, Widen L. J Label Compd Radiopharm 1989; 26: 238-239.
40. Crouzel C, Syrota A. Appl Radiat Isot 1990; 41: 241-242.
41. Holschbach M, Roden W, Hamkens W. J Label Compd Radiopharm 1991; 29: 432-442.
42. Coenen HH, Schueller M, Stoecklin G, Schwenner E. J Label Compd Radiopharm 1991; 30: 245-247.
43. Stone-Elander S, Roland P, Schwenner E, Halldin C, Widen L. Appl Radiat Isot 1991; 42: 871-875.
44. Holschbach M, Coenen HH, Schueller M, Goldmann S, Stoecklin G. J Label Compd Radiopharm 1993; 32: 189-190.
45. Rampe D, Hake PW, Borretzen B, Holm KH, Skattebol L. Eur J Med Chem 1993; 28: 259-263.
46. Satoh Y, Okumura K, Shiokawa Y. Chem Pharm Bull 1994; 42: 950-952.
47. Ohtaka K, Kajiwara M. J Label Compd Radiopharm 2003; 46: 1177-1179.
48. Murphy KMM, Snyder SH. Eur J Pharmacol 1982; 77: 201-202.
49. Goldmann S, Stoltefuss J. Angew Chem Int Ed Engl 1991; 30: 1559-1578.