Six cases of permanent alopecia after various conditioning regimens commonly used in hematopoietic stem cell transplantation

Bone Marrow Transplantation

Volumn 40, Issue 10, 2007, Pages 979-982

  Machado, M ^a   Moreb, J S ^a   Khan, S A ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BUSULFAN; CYCLOPHOSPHAMIDE; CYTARABINE; DEXAMETHASONE; DOXORUBICIN; ETOPOSIDE; IDARUBICIN; IMATINIB; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; TACROLIMUS; VINCRISTINE;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AFRICAN AMERICAN; AGED; ALOPECIA; ALOPECIA AREATA; ARTICLE; AUTOGRAFT; AUTOLOGOUS STEM CELL TRANSPLANTATION; CAUCASIAN; CHRONIC GRAFT VERSUS HOST DISEASE; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CONTINUOUS INFUSION; CORD BLOOD STEM CELL TRANSPLANTATION; DRUG MEGADOSE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; EMOTIONAL DISORDER; EWING SARCOMA; FEMALE; FOLLOW UP; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; INCIDENCE; INFORMED CONSENT; LOW DRUG DOSE; MALE; MEDICOLEGAL ASPECT; MULTIPLE MYELOMA; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SOCIAL PSYCHOLOGY; WHOLE BODY RADIATION;

ADULT; AGED; ALOPECIA; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; TRANSPLANTATION CONDITIONING;

EID: 35748962297     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/sj.bmt.1705817     Document Type: Article

References (29)

1. Dorr VJ. A practitioner's guide to cancer-related alopecia. Semin Oncol 998; 25: 562-570.
2. Hussein AM. Chemotherapy-induced alopecia: New developments. South Med J 1993; 86: 489-496.
3. Baxley KO, Erdman LK, Henry EB, Roof BJ. Alopecia: Effect on cancer patients' body image. Cancer Nurs 1984; 7: 499-503.
4. Tran D, Sinclair RD, Schwarer AP, Chow CW. Permanent alopecia following chemotherapy and bone marrow transplantation. Australia J Dermatol 2000; 41: 106-108.
5. Baker BW, Wilson CL, Davis AL, Spearing RL, Hart DN, Heaton DC et al. Busulphan/cyclophosphamide conditioning for bone marrow transplantation may lead to failure of hair regrowth. Bone Marrow Transplant 1991; 7: 43-47.
6. Vowels M, Chan LL, Giri N, Russell S, Lam-Po-Tang R. Factors affecting hair regrowth after bone marrow transplantation. Bone Marrow Transplant 1993; 12: 347-350.
7. de Jonge ME, Mathot RA, Dalesio O, Huitema AD, Rodenhuis S, Beijnen JH. Relationship between irreversible alopecia and exposure to cyclophosphamide, thiotepa and carboplatin (CTC) in high-dose chemotherapy. Bone Marrow Transplant 2002; 30: 593-597.
8. Ljungman P, Hassan M, Bekassy AN, Ringden O, Oberg G. Busulfan concentration in relation to permanent alopecia in recipients of bone marrow transplants. Bone Marrow Transplant 1995; 15: 869-871.
9. Tosti A, Piraccini BM, Vincenzi C, Misciali C. Permanent alopecia after busulfan chemotherapy. Br J Dermatol 2005; 152: 1056-1058.
10. World Health Organization. Handbook for Reporting Results of Cancer Treatment. WHO publication no. 48, WHO: Geneva, 1979.
11. Massey CS. A multicenter study to determine the efficacy and patient acceptability of the paxman scalp cooler to prevent hair loss in patients receiving chemotherapy. Eur J Oncol Nurs 2004; 8: 121-130.
12. Munstedt K, Manthey N, Sachsse S, Vahrson H. Changes in self-concept and body image during alopecia induced cancer chemotherapy. Support Care Cancer 1997; 5: 139-143.
13. de Boer-Dennert M, de Wit R, Schmitz PI, Djontono J, v Beurden V, Stoter G et al. Patient perceptions of the side-effects of chemotherapy: the influence of 5HT3 antagonists. Br J Cancer 1997; 76: 1055-1061.
14. McGrarvey EL, Baum LD, Pinkerton RC, Rogers LM. Psychological sequelae and alopecia among women with cancer. Cancer Pract 2001; 9: 283-289.
15. Hassan M, Ljungman P, Bolme P, Ringden O, Syruckova Z, Bekassy A et al. Busulfan bioavailabihty. Blood 1994; 84: 2144-2150.
16. Tauchmanova L, Selleri C, De Rosa G, Esposito M, Di Somma C, Orio F et al. Endocrine disorders during the first year after autologous stem-cell transplant, Am J Med 2005; 118: 664-670.
17. Keilholz U, Max R, Scheibenbogen C, Wuster C, Korbling M, Haas R. Endocrine function and bone metabolism 5 years after autologous bone marrow/blood-derived progenitor cell transplantation. Cancer 1997; 79: 1617-1622.
18. Locatelli F, Giorgiani G, Pession A, Bozzola M. Late effects in children after bone marrow transplantation: A review. Haematologica 1993; 78: 319-328.
19. Wang J, Lu Z, Au JL. Protection against chemotherapy-induced alopecia. Pharm Res 2006; 23: 2505-2514.
20. Simister JM. Alopecia and cytotoxic drugs. Br Med J 1966; 2: 1138.
21. Christodoulou C, Klouvas G, Efstathiou E, Zervakis D, Papazachariou E, Plyta M et al. Effectiveness of the MSC cold cap system in the prevention of chemotherapy-induced alopecia. Oncology 2002; 62 97-102.
22. Bleiker TO, Nicolaou N, Traulsen J, Hutchinson PE. Atrophic telogen effluvium from cytotoxic drugs and a randomized trial to investigate the possible protective effect of pretreatment with a topical vitamin D, analogue in humans. Br J Dermatol 2005; 153: 103-112.
23. Sredni B, Xu RH, Albeck M, Gafter U, Gal R, Shani A et al. The protective role of the immunomodulator AS101 against chemotherapy-induced alopecia studies on human and animal models. Int J Cancer 1996; 65: 97-103.
24. Duvic M, Lemak NA, Valero V, Hymes SR, Farmer KL, Hortobagyi GN et al. A randomized trial of minoxidil in chemotherapy-induced alopecia. J Am Acad Dermatol 1996; 35: 74-78.
25. Granai CO, Frederickson H, Gajewski W, Goodman A, Goldstein A, Baden H. The use of minoxidil to attempt to prevent alopecia during chemotherapy for gynecologic malignancies. Eur J Gynaecol Oncol 1991; 12: 129-132.
26. Rodriguez R, Machiavelli M, Leone B, Romero A, Cuevas MA, Langhi M et al. Minoxidil (Mx) as a prophylaxis of doxorubicin - induced alopecia. Ann Oncol 1994; 5: 769-770.
27. Paus R, Handjiski B, Eichmuller S, Czarnetzki BM. Chemotherapy-induced alopecia in mice. Induction by cyclophosphamide, inhibition by cyclosporine A, and modulation by dexamethasone. Am J Pathol 1994; 144: 719-734.
28. Shirai A, Tsunoda H, Tamaoki T, Kamiya T. Topical application of cyclosporin A induces rapid-remodeling of damaged anagen hair follicles produced in cyclophosphamide, administered mice. J Dermatol Sci 2001; 27: 7-13.
29. Hesketh PJ, Batchelor D, Golant M, Lyman GH, Rhodes N, Yardley. D. Chemotherapy-induced alopecia: Psychosocial impact and therapeutic approaches. Support Care Cancer 2004; 12: 543-549.