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Volumn 116, Issue 6, 2007, Pages 392-398

The APOE polymorphism and 1-year outcome in ischemic stroke: Genotype-gender interaction

Author keywords

Apolipoprotein E; Gender; Outcome; Polymorphism; Stroke

Indexed keywords

APOLIPOPROTEIN E; APOLIPOPROTEIN E2; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4;

EID: 35748961097     PISSN: 00016314     EISSN: 16000404     Source Type: Journal    
DOI: 10.1111/j.1600-0404.2007.00880.x     Document Type: Article
Times cited : (35)

References (52)
  • 1
    • 4143091289 scopus 로고    scopus 로고
    • Apolipoprotein E: Diversity of cellular origins, structural and biophysical properties, and effects in Alzheimer's disease
    • Huang Y, Weisgraber KH, Mucke L, Mahley RW. Apolipoprotein E: diversity of cellular origins, structural and biophysical properties, and effects in Alzheimer's disease. J Mol Neurosci 2004 23 : 189 204.
    • (2004) J Mol Neurosci , vol.23 , pp. 189-204
    • Huang, Y.1    Weisgraber, K.H.2    Mucke, L.3    Mahley, R.W.4
  • 2
    • 33244482562 scopus 로고    scopus 로고
    • Presence of an APOE4 allele results in significantly earlier onset of Parkinson's disease and a higher risk with dementia
    • Pankratz N, Byder L, Halter C et al. Presence of an APOE4 allele results in significantly earlier onset of Parkinson's disease and a higher risk with dementia. Mov Disord 2006 21 : 45 9.
    • (2006) Mov Disord , vol.21 , pp. 45-9
    • Pankratz, N.1    Byder, L.2    Halter, C.3
  • 3
    • 2942562810 scopus 로고    scopus 로고
    • Apolipoprotein e controls the risk and age at onset of Parkinson disease
    • Li YJ, Hauser MA, Scott WK et al. Apolipoprotein E controls the risk and age at onset of Parkinson disease. Neurology 2004 62 : 2005 9.
    • (2004) Neurology , vol.62 , pp. 2005-9
    • Li, Y.J.1    Hauser, M.A.2    Scott, W.K.3
  • 4
    • 0035845431 scopus 로고    scopus 로고
    • Apolipoprotein e epsilon 4 is associated with rapid progression of multiple sclerosis
    • Fazekas F, Strasser-Fuchs S, Kollegger H et al. Apolipoprotein E epsilon 4 is associated with rapid progression of multiple sclerosis. Neurology 2001 57 : 853 7.
    • (2001) Neurology , vol.57 , pp. 853-7
    • Fazekas, F.1    Strasser-Fuchs, S.2    Kollegger, H.3
  • 5
    • 19944433201 scopus 로고    scopus 로고
    • Apolipoprotein e is associated with age at onset of amyotrophic lateral sclerosis
    • Li YJ, Pericak-Vance MA, Haines JL et al. Apolipoprotein E is associated with age at onset of amyotrophic lateral sclerosis. Neurogenetics 2004 5 : 209 13.
    • (2004) Neurogenetics , vol.5 , pp. 209-13
    • Li, Y.J.1    Pericak-Vance, M.A.2    Haines, J.L.3
  • 6
    • 0037292267 scopus 로고    scopus 로고
    • Effect of apolipoprotein e genotype on in-hospital mortality following intracerebral haemorrhage
    • Mccarron MO, Weir CJ, Muir KW et al. Effect of apolipoprotein E genotype on in-hospital mortality following intracerebral haemorrhage. Acta Neurol Scand 2003 107 : 106 9.
    • (2003) Acta Neurol Scand , vol.107 , pp. 106-9
    • McCarron, M.O.1    Weir, C.J.2    Muir, K.W.3
  • 7
    • 0031595697 scopus 로고    scopus 로고
    • The Apolipoprotein e epsilon 4 allele and outcome in cerebrovascular disease
    • Mccarron MO, Muir KW, Weir CJ et al. The Apolipoprotein E epsilon 4 allele and outcome in cerebrovascular disease. Stroke 1998 29 : 1882 7.
    • (1998) Stroke , vol.29 , pp. 1882-7
    • McCarron, M.O.1    Muir, K.W.2    Weir, C.J.3
  • 8
    • 27644546646 scopus 로고    scopus 로고
    • The association between APOE e4, age and outcome after head injury: A prospective cohort study
    • Teasdale GM, Murray GD, Nicoli AR. The association between APOE e4, age and outcome after head injury: a prospective cohort study. Brain 2005 128 : 2556 61.
    • (2005) Brain , vol.128 , pp. 2556-61
    • Teasdale, G.M.1    Murray, G.D.2    Nicoli, A.R.3
  • 9
    • 0041328737 scopus 로고    scopus 로고
    • Association between apolipoprotein e genotype and outcome of traumatic brain injury
    • Chiang MF, Chang JG, Hu CJ. Association between apolipoprotein E genotype and outcome of traumatic brain injury. Acta Neurochir (Wien) 2003 145 : 649 53.
    • (2003) Acta Neurochir (Wien) , vol.145 , pp. 649-53
    • Chiang, M.F.1    Chang, J.G.2    Hu, C.J.3
  • 10
    • 0037046213 scopus 로고    scopus 로고
    • APOE genotype influences acquisition and recall following traumatic brain injury
    • Crawford FC, Vanderploeg RD, Freeman MJ et al. APOE genotype influences acquisition and recall following traumatic brain injury. Neurology 2002 58 : 1115 8.
    • (2002) Neurology , vol.58 , pp. 1115-8
    • Crawford, F.C.1    Vanderploeg, R.D.2    Freeman, M.J.3
  • 12
    • 0029765553 scopus 로고    scopus 로고
    • Apolipoprotein e allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides
    • Miyata M, Smith JD. Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides. Nat Genet 1996 14 : 55 61.
    • (1996) Nat Genet , vol.14 , pp. 55-61
    • Miyata, M.1    Smith, J.D.2
  • 13
    • 0035283401 scopus 로고    scopus 로고
    • Apolipoprotein e modulates glial activation and the endogenous central nervous system inflammatory response
    • Lynch JR, Morgan D, Mance J, Matthew WD, Laskowitz DT. Apolipoprotein E modulates glial activation and the endogenous central nervous system inflammatory response. J Neuroimmunol 2001 114 : 107 13.
    • (2001) J Neuroimmunol , vol.114 , pp. 107-13
    • Lynch, J.R.1    Morgan, D.2    Mance, J.3    Matthew, W.D.4    Laskowitz, D.T.5
  • 14
    • 0030610645 scopus 로고    scopus 로고
    • Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein e
    • Barger SW, Harmon AD. Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E. Nature 1997 388 : 878 81.
    • (1997) Nature , vol.388 , pp. 878-81
    • Barger, S.W.1    Harmon, A.D.2
  • 15
    • 4143061183 scopus 로고    scopus 로고
    • A dual role for apolipoprotein e in neuroinflammation: Anti- and pro-inflammatory activity
    • Guo L, Ladu MJ, Van Eldik LJ. A dual role for apolipoprotein e in neuroinflammation: anti- and pro-inflammatory activity. J Mol Neurosci 2004 23 : 205 12.
    • (2004) J Mol Neurosci , vol.23 , pp. 205-12
    • Guo, L.1    Ladu, M.J.2    Van Eldik, L.J.3
  • 16
    • 33645808672 scopus 로고    scopus 로고
    • Apolipoprotein E4: A causative factor and therapeutic target in neuropathology, including Alzheimer's disease
    • Mahley RW, Weisgraber KH, Huang Y. Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease. Proc Natl Acad Sci U S A 2006 103 : 5644 51.
    • (2006) Proc Natl Acad Sci U S a , vol.103 , pp. 5644-51
    • Mahley, R.W.1    Weisgraber, K.H.2    Huang, Y.3
  • 17
    • 33745751979 scopus 로고    scopus 로고
    • Apolipoprotein E-derived peptides reduce CNS inflammation: Implications for therapy of neurological disease
    • Laskowitz DT, Fillit H, Yeung N, Toku K, Vitek MP. Apolipoprotein E-derived peptides reduce CNS inflammation: implications for therapy of neurological disease. Acta Neurol Scand Suppl 2006 185 : 15 20.
    • (2006) Acta Neurol Scand Suppl , vol.185 , pp. 15-20
    • Laskowitz, D.T.1    Fillit, H.2    Yeung, N.3    Toku, K.4    Vitek, M.P.5
  • 18
    • 0035949758 scopus 로고    scopus 로고
    • Apolipoprotein e genotype, coagulation, and survival following acute stroke
    • Weir CJ, Mccarron MO, Muir KW et al. Apolipoprotein E genotype, coagulation, and survival following acute stroke. Neurology 2001 57 : 1097 100.
    • (2001) Neurology , vol.57 , pp. 1097-100
    • Weir, C.J.1    McCarron, M.O.2    Muir, K.W.3
  • 19
    • 0033782077 scopus 로고    scopus 로고
    • Prospective study of apolipoprotein e genotype and functional outcome following ischemic stroke
    • Mccarron MO, Muir KW, Nicoll JA et al. Prospective study of apolipoprotein E genotype and functional outcome following ischemic stroke. Arch Neurol 2000 57 : 1480 4.
    • (2000) Arch Neurol , vol.57 , pp. 1480-4
    • McCarron, M.O.1    Muir, K.W.2    Nicoll, J.A.3
  • 20
    • 0034037568 scopus 로고    scopus 로고
    • Apolipoprotein e polymorphism in cerebrovascular disease
    • Catto AJ, Mccormack LJ, Mansfield MW et al. Apolipoprotein E polymorphism in cerebrovascular disease. Acta Neurol Scand 2000 101 : 399 404.
    • (2000) Acta Neurol Scand , vol.101 , pp. 399-404
    • Catto, A.J.1    McCormack, L.J.2    Mansfield, M.W.3
  • 21
    • 0035954324 scopus 로고    scopus 로고
    • Gender and age modify the association between APOE and AD-related neuropathology
    • Ghebremedhin E, Schultz C, Thal DR et al. Gender and age modify the association between APOE and AD-related neuropathology. Neurology 2001 56 : 1696 701.
    • (2001) Neurology , vol.56 , pp. 1696-701
    • Ghebremedhin, E.1    Schultz, C.2    Thal, D.R.3
  • 22
    • 0035838418 scopus 로고    scopus 로고
    • A gender difference in the association between APOE genotype and age-related cognitive decline
    • Mortensen EL, Hogh PA. A gender difference in the association between APOE genotype and age-related cognitive decline. Neurology 2001 57 : 89 95.
    • (2001) Neurology , vol.57 , pp. 89-95
    • Mortensen, E.L.1    Hogh, P.A.2
  • 23
    • 0035187751 scopus 로고    scopus 로고
    • Is the apoE4 allele an independent predictor of coronary events?
    • Scuteri A, Bos AJ, Zonderman AB et al. Is the apoE4 allele an independent predictor of coronary events? Am J Med 2001 110 : 28 32.
    • (2001) Am J Med , vol.110 , pp. 28-32
    • Scuteri, A.1    Bos, A.J.2    Zonderman, A.B.3
  • 25
    • 0023926955 scopus 로고
    • Stroke Data Bank: Design, methods, and baseline characteristic
    • Foulkes M, Wolf P, Price T. Stroke Data Bank: design, methods, and baseline characteristic. Stroke 1988 19 : 547 54.
    • (1988) Stroke , vol.19 , pp. 547-54
    • Foulkes, M.1    Wolf, P.2    Price, T.3
  • 26
    • 0021970991 scopus 로고
    • Multicenter trial of hemodilution in ischemic stroke-background and study protocol
    • Scandinavian Stroke Study Group.
    • Scandinavian Stroke Study Group. Multicenter trial of hemodilution in ischemic stroke-background and study protocol. Stroke 1985 16 : 885 90.
    • (1985) Stroke , vol.16 , pp. 885-90
  • 27
    • 70450195021 scopus 로고
    • Functional evaluation: The Barthel Index
    • Mahoney FI, Barthel D. Functional evaluation: the Barthel Index. Maryland State Med J 1965 14 : 56 61.
    • (1965) Maryland State Med J , vol.14 , pp. 56-61
    • Mahoney, F.I.1    Barthel, D.2
  • 28
    • 0023889706 scopus 로고
    • Intraobserver agreement for the assessment of handicap in stroke patients
    • Van Swieten JC, Koudstaal PJ, Visser MC. Intraobserver agreement for the assessment of handicap in stroke patients. Stroke 1988 19 : 604 7.
    • (1988) Stroke , vol.19 , pp. 604-7
    • Van Swieten, J.C.1    Koudstaal, P.J.2    Visser, M.C.3
  • 29
    • 0025257612 scopus 로고
    • Restriction isotyping of human apolipoprotein e by gene amplification and cleavage with HhaI
    • Hixson JE, Vernier DT. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res 1990 31 : 545 8.
    • (1990) J Lipid Res , vol.31 , pp. 545-8
    • Hixson, J.E.1    Vernier, D.T.2
  • 30
    • 0031971819 scopus 로고    scopus 로고
    • Assessment of clinical outcomes in acute stroke trials
    • Roberts L, Counsell C. Assessment of clinical outcomes in acute stroke trials. Stroke 1998 29 : 986 91.
    • (1998) Stroke , vol.29 , pp. 986-91
    • Roberts, L.1    Counsell, C.2
  • 31
    • 7944231232 scopus 로고    scopus 로고
    • Lower serum triglyceride level is associated with increased stroke severity
    • Dziedzic T, Słowik A, Gryz EA. Lower serum triglyceride level is associated with increased stroke severity. Stroke 2004 35 : e151 2.
    • (2004) Stroke , vol.35
    • Dziedzic, T.1    Słowik, A.2    Gryz, E.A.3
  • 32
    • 0033577169 scopus 로고    scopus 로고
    • Increased neuronal damage in apolipoprotein E-deficient mice following global ischaemia
    • Horsburgh K, Kelly S, Mcculloch J et al. Increased neuronal damage in apolipoprotein E-deficient mice following global ischaemia. Neuroreport 1999 10 : 837 41.
    • (1999) Neuroreport , vol.10 , pp. 837-41
    • Horsburgh, K.1    Kelly, S.2    McCulloch, J.3
  • 33
    • 0032901189 scopus 로고    scopus 로고
    • Apolipoprotein e deficiency worsens outcome from global cerebral ischemia in the mouse
    • Sheng H, Laskowitz DT, Mackensen GB et al. Apolipoprotein E deficiency worsens outcome from global cerebral ischemia in the mouse. Stroke 1999 30 : 1118 24.
    • (1999) Stroke , vol.30 , pp. 1118-24
    • Sheng, H.1    Laskowitz, D.T.2    MacKensen, G.B.3
  • 34
    • 33847224449 scopus 로고    scopus 로고
    • APOE varepsilon3 gene transfer attenuates brain damage after experimental stroke
    • Epub ahead of print).
    • Coll BW, Mcgregor AL, Wong A et al. APOE varepsilon3 gene transfer attenuates brain damage after experimental stroke. J Cereb Blood Flow Metab 2007 27 : 477 87 (Epub ahead of print).
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 477-87
    • Coll, B.W.1    McGregor, A.L.2    Wong, A.3
  • 35
    • 0034603415 scopus 로고    scopus 로고
    • The role of apolipoprotein e in Alzheimer's disease, acute brain injury and cerebrovascular disease: Evidence of common mechanisms and utility of animal models
    • Horsburgh K, Mccarron MO, White F, Nicoll JA. The role of apolipoprotein E in Alzheimer's disease, acute brain injury and cerebrovascular disease: evidence of common mechanisms and utility of animal models. Neurobiol Aging 2000 21 : 245 55.
    • (2000) Neurobiol Aging , vol.21 , pp. 245-55
    • Horsburgh, K.1    McCarron, M.O.2    White, F.3    Nicoll, J.A.4
  • 36
    • 0033041272 scopus 로고    scopus 로고
    • Influence of apolipoprotein e genotype on neuronal damage and apoE immunoreactivity in human hippocampus following global ischemia
    • Horsburgh K, Graham DI, Stewart J, Nicoll JA. Influence of apolipoprotein E genotype on neuronal damage and apoE immunoreactivity in human hippocampus following global ischemia. J Neuropathol Exp Neurol 1999 58 : 227 34.
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 227-34
    • Horsburgh, K.1    Graham, D.I.2    Stewart, J.3    Nicoll, J.A.4
  • 37
    • 20844434785 scopus 로고    scopus 로고
    • Alzheimer's Disease Cooperative Study. Sex, apolipoprotein e epsilon 4 status, and hippocampal volume in mild cognitive impairment
    • Fleisher A, Grundman M, Jack cr JR et al. Alzheimer's Disease Cooperative Study. Sex, apolipoprotein E epsilon 4 status, and hippocampal volume in mild cognitive impairment. Arch Neurol 2005 62 : 953 7.
    • (2005) Arch Neurol , vol.62 , pp. 953-7
    • Fleisher, A.1    Grundman, M.2    Jack Cr, J.R.3
  • 38
    • 0037046184 scopus 로고    scopus 로고
    • APOE genotype and survival in men and women with Alzheimer's disease
    • Dal Forno G, Carson KA, Brookmeyer R et al. APOE genotype and survival in men and women with Alzheimer's disease. Neurology 2002 58 : 1045 50.
    • (2002) Neurology , vol.58 , pp. 1045-50
    • Dal Forno, G.1    Carson, K.A.2    Brookmeyer, R.3
  • 39
    • 0035061508 scopus 로고    scopus 로고
    • Schizophrenic women with the APOE epsilon 4 allele have a worse prognosis than those without it
    • Martorell L, Virgos C, Valero J et al. Schizophrenic women with the APOE epsilon 4 allele have a worse prognosis than those without it. Mol Psychiatry 2001 6 : 307 10.
    • (2001) Mol Psychiatry , vol.6 , pp. 307-10
    • Martorell, L.1    Virgos, C.2    Valero, J.3
  • 41
    • 0038017246 scopus 로고    scopus 로고
    • Apolipoprotein e gene polymorphism and colorectal cancer: Gender-specific modulation of risk and prognosis
    • Watson MA, Gay L, Stebbings WS et al. Apolipoprotein E gene polymorphism and colorectal cancer: gender-specific modulation of risk and prognosis. Clin Sci (Lond) 2003 104 : 537 45.
    • (2003) Clin Sci (Lond) , vol.104 , pp. 537-45
    • Watson, M.A.1    Gay, L.2    Stebbings, W.S.3
  • 42
    • 0034127395 scopus 로고    scopus 로고
    • Apolipoprotein e genotype: Epsilon32 women are protected while epsilon43 and epsilon44 men are susceptible to ischemic heart disease: The Copenhagen City Heart Study
    • Frikke-Schmidt R, Tybjaerg-Hansen A, Steffensen R, Jensen G, Nordestgaard BG. Apolipoprotein E genotype: epsilon32 women are protected while epsilon43 and epsilon44 men are susceptible to ischemic heart disease: the Copenhagen City Heart Study. J Am Coll Cardiol 2000 35 : 1192 9.
    • (2000) J Am Coll Cardiol , vol.35 , pp. 1192-9
    • Frikke-Schmidt, R.1    Tybjaerg-Hansen, A.2    Steffensen, R.3    Jensen, G.4    Nordestgaard, B.G.5
  • 43
    • 0028174820 scopus 로고
    • Effects of gender and menopausal status on the association of apolipoprotein e phenotype with plasma lipoprotein levels. Results from the Framingham Offspring Study
    • Schaefer EJ, Lamon-Fava S, Johnson S et al. Effects of gender and menopausal status on the association of apolipoprotein E phenotype with plasma lipoprotein levels. Results from the Framingham Offspring Study. Arterioscler Thromb 1994 14 : 1105 13.
    • (1994) Arterioscler Thromb , vol.14 , pp. 1105-13
    • Schaefer, E.J.1    Lamon-Fava, S.2    Johnson, S.3
  • 45
    • 12144287738 scopus 로고    scopus 로고
    • Low cholesterol levels are associated with short-term mortality in older patients with ischemic stroke
    • Zuliani G, Cherubini A, Atti AR et al. Low cholesterol levels are associated with short-term mortality in older patients with ischemic stroke. J Gerontol A Biol Sci Med Sci 2004 59 : 293 7.
    • (2004) J Gerontol a Biol Sci Med Sci , vol.59 , pp. 293-7
    • Zuliani, G.1    Cherubini, A.2    Atti, A.R.3
  • 46
    • 0021063857 scopus 로고
    • Sex-related differences in the concentrations of apolipoprotein e in human blood plasma and plasma lipoproteins
    • Phillips NR, Havel RJ, Kane JP. Sex-related differences in the concentrations of apolipoprotein E in human blood plasma and plasma lipoproteins. J Lipid Res 1983 24 : 1525 31.
    • (1983) J Lipid Res , vol.24 , pp. 1525-31
    • Phillips, N.R.1    Havel, R.J.2    Kane, J.P.3
  • 47
    • 0037096337 scopus 로고    scopus 로고
    • Androgens protect against apolipoprotein E4-induced cognitive deficits
    • Raber J, Bongers G, Lefevour A, Buttini M, Mucke L. Androgens protect against apolipoprotein E4-induced cognitive deficits. J Neurosci 2002 22 : 5204 9.
    • (2002) J Neurosci , vol.22 , pp. 5204-9
    • Raber, J.1    Bongers, G.2    Lefevour, A.3    Buttini, M.4    Mucke, L.5
  • 48
    • 0036772287 scopus 로고    scopus 로고
    • Apolipoprotein e gene determines serum testosterone and dehydroepiandrosterone levels in postmenopausal women
    • Zofkova I, Zajickova K, Hill M, Horinek A. Apolipoprotein E gene determines serum testosterone and dehydroepiandrosterone levels in postmenopausal women. Eur J Endocrinol 2002 147 : 503 6.
    • (2002) Eur J Endocrinol , vol.147 , pp. 503-6
    • Zofkova, I.1    Zajickova, K.2    Hill, M.3    Horinek, A.4
  • 49
    • 0033013378 scopus 로고    scopus 로고
    • Local estrogen biosynthesis in males and females
    • Simpson E, Rubin G, Clyne C et al. Local estrogen biosynthesis in males and females. Endocr Relat Cancer 1999 6 : 131 7.
    • (1999) Endocr Relat Cancer , vol.6 , pp. 131-7
    • Simpson, E.1    Rubin, G.2    Clyne, C.3
  • 50
    • 11444251209 scopus 로고    scopus 로고
    • Sex steroids, APOE genotype and the innate immune system
    • Colton CA, Brown CM, Vitek MP. Sex steroids, APOE genotype and the innate immune system. Neurobiol Aging 2005 263 : 363 72.
    • (2005) Neurobiol Aging , vol.263 , pp. 363-72
    • Colton, C.A.1    Brown, C.M.2    Vitek, M.P.3
  • 51
    • 33748967907 scopus 로고    scopus 로고
    • Inflammatory markers and in- hospital mortality in acute ischaemic stroke
    • Rallidis LS, Vikelis M, Panagiotakos DB. Inflammatory markers and in- hospital mortality in acute ischaemic stroke. Atherosclerosis 2006 189 : 193 7.
    • (2006) Atherosclerosis , vol.189 , pp. 193-7
    • Rallidis, L.S.1    Vikelis, M.2    Panagiotakos, D.B.3
  • 52
    • 33744779094 scopus 로고    scopus 로고
    • Inflammatory biomarkers in blood of patients with acute brain ischemia
    • Sotgiu S, Zanda B, Marchetti B et al. Inflammatory biomarkers in blood of patients with acute brain ischemia. Eur J Neurol 2006 13 : 505 13.
    • (2006) Eur J Neurol , vol.13 , pp. 505-13
    • Sotgiu, S.1    Zanda, B.2    Marchetti, B.3


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