The role of clusterin in retinal development and free radical damage

British Journal of Ophthalmology

Volumn 91, Issue 11, 2007, Pages 1541-1546

  Kim, Jeong Hun ^a   Kim, Jin Hyoung ^b   Yu, Young Suk ^a   Min, Bon Hong ^c   Kim, Kyu Won ^b  

^a Seoul National University Hospital   (South Korea)

^b Seoul National University   (South Korea)

^c Korea University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CLUSTERIN; FREE RADICAL; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; HYDROGEN PEROXIDE; OXYGEN; VASCULOTROPIN RECEPTOR 2; VON WILLEBRAND FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; ASTROCYTE; CELL HYPOXIA; CELL VIABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RETINA DEVELOPMENT; VASCULAR DISEASE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; CELL HYPOXIA; CELLS, CULTURED; CLUSTERIN; FREE RADICALS; HYDROGEN PEROXIDE; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; RETINA; RETINAL DISEASES; RETINAL VESSELS;

EID: 35748939116     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.2007.115220     Document Type: Article

References (38)

1. Kissinger C, Skinner MK, Griswold MD. Analysis of Sertoli cell-secreted proteins by two-dimensional gel electrophoresis. Biol Reprod 1982;27:233-40.
2. Blaschuk O, Burdzy K, Fritz IB. Purification and characterization of a cell-aggregating factor (clusterin), the major glycoprotein in ram rete testis fluid. J Biol Chem 1983;258:7714-20.
3. May PC, Finch CE. Sulfated glycoprotein 2: new relationships of this multifunctional protein to neurodegeneration. Trends Neurosci 1992;15:391-6.
4. Wilson MR, Easterbrook-Smith SB. Clusterin Is a secreted mammalian chaperone. Trends Biochem Sci 2000;25:95-8.
5. Rosenberg ME, Silkensen J. Clusterin: physiologic and pathophysiologic considerations. Int J Biochem Cell Biol 1995;27:633-45.
6. Koch-Brandt C, Morgans C. Clusterin: A role in cell survival in the face of apoptosis? Prog Mol Subcell Biol 1996;16:130-49.
7. Jenne DE, Tschopp J. Clusterin: the intriguing guises of a widely expressed glvcoprotein. Trends Biochem Sci 1992;17:154-9.
8. Silkensen JR, Schwochau GB, Rosenberg ME. The role of clusterin in tissue injury. Biochem Cell Biol 1994;72:483-7.
9. Kimura K, Asami K, Yamamoto M. Effect of heat shock treatment on the production of variant testosterone-repressed prostate message-2 (TRPM-2) mRNA in culture cells. Cell Biochem Funct 1997;15:251-7.
10. Clark AM, Griswold MD. Expression of clusterin/sulfated glycoprotein-2 under conditions of heat stress in rat Sertoli cells and a mouse Sertoli cell line. J Androl 1997;18:257-63.
11. McLaughlin L, Zhu G, Mistry M, et al. Apolipoprotein J/clusterin limits the severity of murine autoimmune myocarditis. J Clin Invest 2000;106:1105-12.
12. Wehrli P, Charnay Y, Vallet P, et al. Inhibition of post-ischemic brain injury by clusterin overexpression. Nat Med 2001;7:977-9.
13. Rosenberg ME, Girton R, Finkel D, et al. Apolipoprotein J/clusterin prevents a progressive glomeruiopathy of aging. Mol Cell Biol 2002;22:1893-902.
14. Michel D, Chatelain G, North S, et al. Stress-induced transcription of the clusterin/apoJ gene. Biochem J 1997;328:45- 50.
15. O'Bryan MK, Cheema SS, Bartlett PF, et al. Clusterin levels increase during neuronal development. J Neurobiol 1993;24:421-32.
16. Zhang D, Kaufman PL, Gao G, et al. Intravitreal injection of plasminogen kringle 5, an endogenous angiogenic inhibitor, arrests retinal neovascularization in rats. Diabetologia 2001;44:757-65.
17. Shin YJ, Kang SW, Jeong SY, et al. Clusterin enhances proliferation of primary astrocytes through extracellular signal-regulated kinase activation. Neuroreport 2006;17:1871-5.
18. Michaelson IC. The mode of development of the vascular system of the retina, with some observations on its significance for certain retinal diseases. Trans Ophthalmol Soc UK 1948;68:137-81.
19. Chan-Ling T, Halasz P, Stone J. Development of retinal vasculature in the cat: processes and mechanisms. Curr Eye Res 1990;9:459-78.
20. Shabby F, Rossant J, Yamaguchi TP, et al. Failure of blood-island formation and vasculogenesis in FIk-1-deficient mice. Nature 1995;376:62-6.
21. Hawkes EL, Krueger-Naug AM, Nickerson PE, et al. Expression of Hsp27 in retinal ganglion cells of the rat during postnatal development. J Comp Neurol 2004;478:143-8.
22. Patz A. Oxygen studies in retrolental fibroplasia. IV: clinical and experimental observations. Am J Ophthalmol 1954;38:291-307.
23. Ashton N, Ward B, Serpell G. Effect of oxygen on developing retinal vessels with particular reference to the problem of retrolental fibroplasias. Br J Ophthalmol 1954;38:397-428.
24. Engerman RL, Meyer RK. Development of retinal vasculature in rats. Am J Ophthalmol 1965;60:628-41.
25. Connolly SE, Hores TA, Smith LE, et al. Characterization of vascular development in the mouse retina. Microvasc Res 1988;36:275-90.
26. Stone J, Itin A, Alon T, et al. Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia. J Neurosci 1995;15:4738-47.
27. Ohtsuka K, Suzuki T. Roles of molecular chaperones in the nervous system. Brain Res Bull 2000;53:141-0.
28. Kabakov AE, Budagova KR, Bryantsev AL, et al. Heat shock protein 70 or heat shock protein 27 overexpressed in human endothelial cells during posthypoxic reoxygenation can protect from delayed apoptosis. Cell Stress Chaperones 2003;8:335-47.
29. Whitlock NA, Agarwal N, Ma JX, et al. Hsp27 upregulation by hvpoxia-inducible factor (HIF)-1 signaling offers protection against retinal ischemia in rats. Invest Ophthalmol Vis Sci 2005;46:1092-8.
30. Sensibar JA, Sutkowski DM, Raffo A, et al. Prevention of cell death induced by tumor necrosis factor alpha in LNCaP cells by overexpression of sulfated glycoprotein-2 (clusterin). Cancer Res 1995;55:2431-7.
31. Humphreys D, Hochgrebe TT, Easterbrook-Smith SB, et al. Effects of clusterin overexpression on TNFalpha- and TGFbeta-mediated death of L929 cells. Biochemistry 1997;36:15233-43.
32. Viard I, Wehrli P, Jornot L, et al. Clusterin gene expression mediates resistance to apoptotic cell death induced by heat shock and oxidative stress. J Invest Dermatol 1999;112:290-6.
33. Sintich SM, Steinberg J, Kozlowski JM, et al. Cytotoxic sensitivity to tumor necrosis factor-alpha in PC3 and LNCaP prostatic cancer cells is regulated by extracellular levels of SGP-2 (clusterin). Prostate 1999;39:87-93.
34. Schwochau GB, Nath KA, Rosenberg ME. Clusterin protects against oxidative stress in vitro through aggregative and nonaggregative properties. Kidney Int 1998;53:1647-53.
35. Carver JA, Rekas A, Thorn DC, et al. Small heat-shock proteins and clusterin: intra- and extracellular molecular chaperones with a common mechanism of action and function? IUBMB Life 2003;55:661-8.
36. Poon S, Easterbrook-Smith SB, Rybchyn MS, et al. Clusterin is an ATP-independent chaperone with very broad substrate specificity that stabilizes stressed proteins in a folding-competent state. Biochemistry 2000;39:15953-60.
37. Sivamurrhy N, Stone DH, Logerfo FW, et al. Apolipoprotein J inhibits the migration, adhesion, and proliferation of vascular smooth muscle cells. J Vasc Surg 2001;34:716-23.
38. Sivamurthy N, Stone DH, LoGerfo FW, et al. Apolipoprotein J inhibits the migration and adhesion of endothelial cells. Surgery 2001;130:204-9.