Diagnostic value of histology and immunohistochemistry in myelodysplastic syndromes

Leukemia Research

Volumn 31, Issue 12, 2007, Pages 1609-1616

  Horny, Hans Peter ^a   Sotlar, Karl ^b   Valent, Peter ^c  

^a Institute of Pathology   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Blast cells; Bone marrow histology; Immunohistochemistry; Mast cells; Mastocytosis; Myelodysplastic syndromes

Indexed keywords

TRYPTASE;

ANGIOGENESIS; BLOOD SMEAR; BONE MARROW; CD34 SELECTION; CELLULAR DISTRIBUTION; CYTOLOGY; DIAGNOSTIC VALUE; FIBROSIS; HISTOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; MEGAKARYOCYTE; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL; REVIEW; STEM CELL;

BIOLOGICAL MARKERS; BONE MARROW EXAMINATION; HISTOLOGICAL TECHNIQUES; HUMANS; IMMUNOHISTOCHEMISTRY; MYELODYSPLASTIC SYNDROMES;

EID: 35748933230     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2007.05.010     Document Type: Review

References (18)

1. Bennett J.M., Catovsky D., Daniel M.T., Flandrin G., Galton D.A., Gralnick H.R., et al. Proposals for the classification of the myelodysplastic syndromes. Br J Haematol 51 (1982) 189-199
2. Brunning R.D., Bennett J.M., Flandrin G., Matutes E., Head D., Vardiman J.W., et al. Myelodysplastic syndromes. In: Jaffe E.S., Harris N.L., Stein H., and Vardiman J.W. (Eds). World Health Organization classification of tumours. Pathology & genetics. Tumours of haematopoietic and lymphoid tissues vol 1 (2001), IARC Press Lyon 62-73
3. Bennett J.M. A comparative review of classification systems in myelodysplastic syndromes (MDS). Semin Oncol 32 (2005) S3-S10
4. Greenberg P., Cox C., LeBeau M.M., Fenaux P., Morel P., Sanz G., et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood 89 (1997) 2079-2088
5. Lambertenghi-Deliliers G., Annaloro C., Oriani A., and Soligo D. Myelodysplastic syndrome associated with bone marrow fibrosis. Leuk Lymphoma 8 (1992) 51-55
6. Horny H.-P., Wehrmann M., Schlicker H.U., Eichstaedt A., Clemens M.R., and Kaiserling E. QBEND10 for the diagnosis of myelodysplastic syndromes in routinely processed bone marrow biopsy specimens. J Clin Pathol 48 (1995) 291-294
7. Baur A.S., Meuge-Moraw C., Schmidt P.M., Parlier V., Jotterand M., and Delacretaz F. CD34/QBEND10 immunostaining in bone marrow biopsies: an additional parameter for the diagnosis and classification of myelodysplastic syndromes. Eur J Haematol 64 (2000) 71-79
8. Horny H.-P., Greschniok A., Jordan J.H., Menke D.M., and Valent P. Chymase expressing bone marrow mast cells in mastocytosis and myelodysplastic syndromes: an immunohistochemical and morphometric study. J Clin Pathol 56 (2003) 103-106
9. Horny H.-P., Sotlar K., Sperr W.R., and Valent P. Systemic mastocytosis with associated clonal haematological non-mast cell lineage diseases: a histopathological challenge. J Clin Pathol 57 (2004) 604-608
10. Valent P., Horny H.-P., Bennett J.M., Fonatsch C., Germing U., Greenberg P., et al. Definitions and standards in the diagnosis and treatment of the myelodysplastic syndromes: consensus statements and report from a working conference. Leuk Res 31 (2007) 727-736
11. Tricot G., De Wolf-Peeters C., Vlietinck R., and Verwilghen R.L. Bone marrow histology in myelodysplastic syndromes. II. Prognostic value of abnormal localization of immature precursors in MDS. Br J Haematol 58 (1984) 217-225
12. Oriani A., Annaloro C., Soligo D., Pozzoli E., Cortelezzi A., and Lambertenghi Deliliers G. Bone marrow histology and CD34 immunostaining in the prognostic evaluation of primary myelodysplastic syndromes. Br J Haematol 92 (1996) 360-364
13. Horny H.-P., Sotlar K., Stellmacher F., Krokowski M., Agis H., Schwartz L.B., et al. The tryptase-positive compact round cell infiltrate of the bone marrow (TROCI-bm): a novel histopathological finding requiring the application of lineage-specific markers. J Clin Pathol 59 (2006) 298-302
14. Thiele J., Quitmann H., Wagner S., and Fischer R. Dysmegakaryopoiesis in myelodysplastic syndromes (MDS): an immunomorphometric study of bone marrow trephine biopsy specimens. J Clin Pathol 44 (1991) 300-305
15. Agis H., Krauth M.T., Böhm A., Mosberger I., Müllauer L., Simonitsch-Klupp I., et al. Identification of basogranulin (BB1) as a novel immunohistochemical marker of basophils in normal bone marrow and patients with myeloprolferative disorders. Am J Clin Pathol 125 (2006) 1-9
16. Agis H., Krauth M.T., Mosberger I., Müllauer L., Simonitsch-Klupp I., Schwartz L.B., et al. Enumeration and immunohistochemical characterisation of bone marrow basophils in myeloproliferative disorders using the basophil specific antibody 2D7. J Clin Pathol 59 (2006) 396-402
17. Orazi A., O'Malley D.P., Jiang J., Vance G.H., Thomas J., Czader M., et al. Acute panmyelosis with myelofibrosis: an entity distinct from acute megakaryoblastic leukemia. Mod Pathol 18 (2005) 603-614
18. Imbert M., Nguyen D., and Sultan C. Myelodysplastic syndromes (MDS) and acute myeloid leukemias (AML) with myelofibrosis. Leuk Res 16 (1992) 51-54