Factors influencing spontaneous mobilization of CD34+ and CD133+ progenitor cells after myocardial infarction

European Journal of Clinical Investigation

Volumn 37, Issue 11, 2007, Pages 842-851

  Turan, R G ^a   Brehm, M ^a   Koestering, M ^a   Tobias, Z ^a   Bartsch, T ^a   Steiner, S ^a   Picard, F ^a   Ebner, P ^a   Schannwell, C M ^a   Strauer, B E ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Age; Cardiovascular risk factors; Inflammatory markers; Left ventricular function; Myocardial infarction; Stem cells

Indexed keywords

ACETYLSALICYLIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; C REACTIVE PROTEIN; CD133 ANTIGEN; CD34 ANTIGEN; CLOPIDOGREL; CREATINE KINASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HEPARIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; TIROFIBAN;

ADULT; AGED; ARTICLE; BIVARIATE ANALYSIS; CARDIOVASCULAR RISK; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FLOW CYTOMETRY; HEART EJECTION FRACTION; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE FUNCTION; HUMAN; HUMAN CELL; LEUKOCYTE; MALE; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; STEM CELL; STEM CELL MOBILIZATION; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD; ANTIGENS, CD34; BONE MARROW CELLS; CASE-CONTROL STUDIES; CELL SEPARATION; FEMALE; FLOW CYTOMETRY; GLYCOPROTEINS; HEART; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PEPTIDES; REGENERATION; RISK FACTORS; STEM CELLS; VENTRICULAR DYSFUNCTION, LEFT;

EID: 35649028880     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1111/j.1365-2362.2007.01876.x     Document Type: Article

References (41)

1. Luttun A, Carmeliet G, Carmeliet P. Vascular progenitors: from biology to treatment. Trends Cardiovasc Med 2002 12 : 88 96.
2. Szmitko PE, Fedak PWM, Weisel RD, Stewart DJ, Kutryk MJB, Verma S. Endothelial progenitor cells, new hope for a broken heart. Circulation 2003 107 : 3093 100.
3. Yin AH, Miraglia S, Zanjani ED, Almeida-Porada G, Ogawa M, Leary AG et al. AC133, a novel marker for human haematopoietic stem and progenitor cells. Blood 1997 90 : 5002 12.
4. + cells identifies a population of functional endothelial precursors. Blood 2000 95 : 952 8.
5. Asahara T, Masuda H, Takahashi T, Kalka C, Pastore C, Silver M et al. Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res 1999 85 : 221 8.
6. Shintani S, Murohara T, Ikeda H, Ueno T, Honma T, Katoh A et al. Mobilisation of endothelial progenitor cells in patients with acute myocardial infarction. Circulation 2001 103 : 2776 9.
7. + enriched cell population into cardiomyocytes, endothelial cells and smooth muscle cells in vivo. Circulation 2003 108 : 2070 23.
8. Orlic D, Kajstura J, Chimenti S, Limana F, Jakoniuk I, Quaini F et al. Mobilised bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci USA 2001 98 : 10344 9.
9. Orlic D, Kajstura J, Chimenti S, Jakoniuk I, Anderson SM, Li B et al. Bone marrow cells regenerate infarcted myocardium. Nature 2001 410 : 701 5.
10. Kawamoto A, Gwon HC, Iwaguro H, Yamaguchi JI, Uchida S, Masuda H et al. Therapeutic potential of ex vivo expanded endothelial progenitor cells for myocardial ischemia. Circulation 2001 103 : 634 7.
11. Kawamoto A, Tkebuchava T, Yamaguchi JI, Nishimura H, Yoon YS, Milliken C et al. Intramyocardial transplantation of autologous endothelial progenitor cells for therapeutic neovascularization of myocardial ischaemia. Circulation 2003 107 : 461 8.
12. Kocher AA, Schuster MD, Szabolcs MJ, Takuma S, Burkhoff D, Wang J et al. Neovascularization of ischaemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat Med 2001 7 : 430 6.
13. Fuchs S, Baffour R, Zhou YF, Shou M, Pierre A, Tio FO et al. Transendocardial delivery of autologous bone marrow enhances collateral perfusion and regional function in pigs with chronic experimental myocardial ischaemia. J Am Coll Cardiol 2001 37 : 1726 32.
14. + cell determination by flow cytometry. J Hematotherapy 1996 5 : 213 26.
15. + cell counts based on the ISHAGE guidelines. Int Soc Hematotherapy Graft Engineering Cytometry 1998 34 : 61 70.
16. Sheehan FH, Bolson EL, Dodge HT, Mathey DG, Schofer J, Woo HW. Advantages and applications of the Centerline method for characterizing regional ventricular function. Circulation 1986 74 : 293 305.
17. Vita JA, Treasure CB, Nabel EG, McLenachen JM, Fisch RD, Yeung AC. Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease. Circulation 1990 81 : 491 7.
18. Hill JM, Zalos G, Halcox JPJ, Schenke WH, Waclawiw MA, Quyyumi AA et al. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med 2003 348 : 593 600.
19. Vasa M, Fichtlscherer S, Aicher A, Adler K, Urbich C, Martin H et al. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 2001 89 : E1 7.
20. Scheubel RJ, Zorn H, Silber RE, Kuss O, Morawietz H, Holtz J et al. Age-dependent depression in circulating endothelial progenitor cells in patients undergoing coronary artery bypass grafting. J Am Coll Cardiol 2003 42 : 2073 80.
21. Muller-Ehmsen J, Scheid C, Grundmann F, Hirsch I, Turan RG, Tossios P et al. The mobilisation of CD34 positive mononuclear cells after myocardial infarction is abolished by revascularization of the culprit vessel. Int J Cardiol 2005 103 : 7 11.
22. Kondo T, Hayashi M, Takeshita K, Numaguchi Y, Kobayashi K, Iino S et al. Smoking cessation rapidly increases circulating progenitor cells in peripheral blood in chronic smokers. Arterioscler Thromb Vasc Biol 2004 24 : 1442 7.
23. Tepper OM, Galiano RD, Capla JM, Kalka C, Gagne PJ, Jacobowitz GR et al. Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures. Circulation 2002 106 : 2781 6.
24. Rauscher FM, Goldschmidt-Clermont PJ, Davis BH, Wang T, Gregg D. Aging, progenitor cell exhaustion, and atherosclerosis. Circulation 2003 108 : 457 63.
25. Dimmeler S, Zeiher AM. Vascular repair by circulating endothelial progenitor cells: the missing link in atherosclerosis. J Moll Med 2004 82 : 671 7.
26. Urbich C, Dimmeler S. Endothelial progenitor cell; characterization and role in vascular biology. Circ Res 2004 95 : 343 53.
27. Strauer BE, Brehm M, Zeus T, Köstering M, Hernandez A, Sorg RV et al. Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans. Circulation 2002 106 : 1913 8.
28. Tse HF, Chan KJY, Lo G, Ho C, Lau C. Angiogenesis in ischaemic myocardium by intramyocardial autologous bone marrow mononuclear transplantation. Lancet 2003 361 : 47 9.
29. Stamm C, Westphal B, Kleine H, Petzsch M, Kittner C, Klinge H et al. Autologous bone-marrow stem-cell transplantation for myocardial regeneration. Lancet 2003 361 : 45 6.
30. Wollert GM, Lotz J, Lichtenberg SR, Lippolt P, Breidenbach C, Fichtner S et al. Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet 2004 364 : 141 8.
31. Strauer BE, Brehm M, Zeus T, Bartsch T, Schannwell CM, Antke C et al. Regeneration of human infarcted heart muscle by intracoronary autologous bone marrow cell transplantation in chronic coronary artery disease (The IACT Study). JACC 2005 46 : 1651 8.
32. Ince H, Petzsch M, Kleine HD, Schmidt H, Rehders T, Körber T et al. Preservation from left ventricular remodeling by front-integrated revascularization and stem cell liberation in evolving acute myocardial infarction using granulocyte colony stimulating factor (FIRSTLINE-AMI). Circulation 2005 112 : 3097 106.
33. Schachinger V, Erbs S, Elsasser A, Haberbosch W, Hambrecht R, Holschermann H et al. Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction. N Engl J Med 2006 355 : 1210 21.
34. Assmus B, Honold J, Schachinger V, Britten MB, Fischer-Rasokat U, Lehmann R et al. Transcoronary transplantation of progenitor cells after myocardial infarction. N Engl J Med 2006 355 : 1222 32.
35. + and endothelial progenitor cells in patients with various degrees of congestive heart failure. Circulation 2004 110 : 1209 12.
36. Heeschen C, Lehmann R, Honold J, Assmus B, Aicher A, Walter DH et al. Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischaemic heart disease. Circulation 2004 109 : 1615 22.
37. Hoffman M, Blum A, Baruch R, Kaplan E, Benjamin M. Leukocytes and coronary heart disease. Atherosclerosis 2004 172 : 1 6.
38. Friedman GD, Klatsky AL, Siegelaub AB. The leukocyte count as a predictor of myocardial infarction. N Engl J Med 1974 290 : 1275 8.
39. Haverkate F, Thompson SG, Pyke SDM, Gallimore J, Group M. Production of C- reactive protein and risk of coronary events in stable and unstable angina. Lancet 1997 349 : 462 6.
40. Verma S, Kuliszewski MA, Li SH, Szmitko PE, Zucco L, Wang CH et al. C-reactive protein attenuates endothelial progenitor cell survival, differentiation, and function. Circulation 2004 109 : 2058 67.
41. Vasan RS, Sullivan LM, Roubenoff R, Dinarello CA, Harris T, Benjamin EJ et al. Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction. Circulation 2003 107 : 1486 91.