An upstream CRE-E-box element is essential for gastrin-dependent activation of the cyclooxygenase-2 gene in human colon cancer cells

Regulatory Peptides

Volumn 144, Issue 1-3, 2007, Pages 25-33

  Ansorge, Nikolaus ^a   Jüttner, Stefan ^b   Cramer, Thorsten ^b   Schmidt, Wolfgang E ^a   Höcker, Michael ^b   Schmitz, Frank ^a  

^a ST JOSEF HOSPITAL   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Colon carcinoma; COX 2 gene promoter; CRE E box; USF1 2

Indexed keywords

1 (2,3 DIHYDRO 1 METHYL 2 OXO 5 PHENYL 1H 1,4 BENZODIAZEPIN 3 YL) 3 (3 METHYLPHENYL)UREA; ARACHIDONIC ACID; CHOLECYSTOKININ B RECEPTOR; COMPLEMENTARY DNA; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; GASTRIN; GASTRIN RECEPTOR; LUCIFERASE; PROSTAGLANDIN E2; UPSTREAM STIMULATORY FACTOR 1; UPSTREAM STIMULATORY FACTOR 2;

ARACHIDONIC ACID METABOLISM; ARTICLE; CANCER CELL CULTURE; COLORECTAL CARCINOMA; CONTROLLED STUDY; E BOX ELEMENT; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HORMONAL REGULATION; HORMONE ACTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROSTAGLANDIN SYNTHESIS; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE;

BINDING SITES; COLONIC NEOPLASMS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLOOXYGENASE 2; DINOPROSTONE; GASTRINS; HUMANS; PROMOTER REGIONS (GENETICS); RESPONSE ELEMENTS; RNA, MESSENGER; TRANS-ACTIVATION (GENETICS); TRANSFECTION; TUMOR CELLS, CULTURED; UPSTREAM STIMULATORY FACTORS;

CITRUS MACROPHYLLA;

EID: 35649028676     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.regpep.2007.05.005     Document Type: Article

References (33)

1. Sung J.J., Leung W.K., Go M.Y., To K.F., Cheng A.S., Ng E.K., and Chan F.K. Cyclooxygenase-2 expression in Helicobacter pylori-associated premalignant and malignant gastric lesions. Am J Pathol 157 3 (2000) 729-735
2. Lim H.Y., Joo H.J., Choi J.H., Yi J.W., Yang M.S., Cho D.Y., Kim H.S., Nam D.K., Lee K.B., and Kim H.C. Increased expression of cyclooxygenase-2 protein in human gastric carcinoma. Clin Cancer Res 6 2 (2000) 519-525
3. Ristimaki A., Honkanen N., Jankala H., Sipponen P., and Harkonen M. Expression of cyclooxygenase-2 in human gastric carcinoma. Cancer Res 57 7 (1997) 1276-1280
4. Williams C., Shattuck-Brandt R.L., and DuBois R.N. The role of COX-2 in intestinal cancer. Ann N Y Acad Sci 889 (1999) 72-83
5. Ohno R., Yoshinaga K., Fujita T., Hasegawa K., Iseki H., Tsunozaki H., Ichikawa W., Nihei Z., and Sugihara K. Depth of invasion parallels increased cyclooxygenase-2 levels in patients with gastric carcinoma. Cancer 91 10 (2001) 1876-1881
6. Sawaoka H., Kawano S., Tsuji S., Tsujii M., Gunawan E.S., Takei Y., Nagano K., and Hori M. Cyclooxygenase-2 inhibitors suppress the growth of gastric cancer xenografts via induction of apoptosis in nude mice. Am J Physiol 274 6 Pt 1 (1998) G1061-G1067
7. Sawaoka H., Kawano S., Tsuji S., Tsujii M., Murata H., and Hori M. Effects of NSAIDs on proliferation of gastric cancer cells in vitro: possible implication of cyclooxygenase-2 in cancer development. J Clin Gastroenterol 27 Suppl 1 (1998) S47-S52
8. Farrow D.C., Vaughan T.L., Hansten P.D., Stanford J.L., Risch H.A., Gammon M.D., Chow W.H., Dubrow R., Ahsan H., Mayne S.T., Schoenberg J.B., West A.B., Rotterdam H., Fraumeni Jr. J.F., and Blot W.J. Use of aspirin and other nonsteroidal anti-inflammatory drugs and risk of esophageal and gastric cancer. Cancer Epidemiol Biomarkers Prev 7 2 (1998) 97-102
9. Kawai N., Tsujii M., and Tsuji S. Cyclooxygenases and colon cancer. Prostaglandins Other Lipid Mediat 68-69 (2002) 187-196
10. Inoue H., Nanayama T., Hara S., Yokoyama C., and Tanabe T. The cyclic AMP response element plays an essential role in the expression of the human prostaglandin-endoperoxide synthase 2 gene in differentiated U937 monocytic cells. FEBS Lett 350 1 (1994) 51-54
11. Guo Y.S., Cheng J.Z., Jin G.F., Gutkind J.S., Hellmich M.R., and Townsend Jr. C.M. Gastrin stimulates cyclooxygenase-2 expression in intestinal epithelial cells through multiple signaling pathways. Evidence for involvement of ERK5 kinase and transactivation of the epidermal growth factor receptor. J Biol Chem 277 50 (2002) 48755-48763
12. Rozengurt E., and Walsh J.H. Gastrin, CCK, signaling, and cancer. Annu Rev Physiol 63 (2001) 49-76
13. Upp Jr. J.R., Singh P., Townsend Jr. C.M., and Thompson J.C. Clinical significance of gastrin receptors in human colon cancers. Cancer Res 49 2 (1989) 488-492
14. Schmitz F., Otte J.M., Stechele H.U., Reimann B., Banasiewicz T., Folsch U.R., Schmidt W.E., and Herzig K.H. CCK-B/gastrin receptors in human colorectal cancer. Eur J Clin Invest 31 9 (2001) 812-820
15. Ciccotosto G.D., McLeish A., Hardy K.J., and Shulkes A. Expression, processing, and secretion of gastrin in patients with colorectal carcinoma. Gastroenterology 109 4 (1995) 1142-1153
16. Watson S.A., Clarke P.A., Morris T.M., and Caplin M.E. Antiserum raised against an epitope of the cholecystokinin B/gastrin receptor inhibits hepatic invasion of a human colon tumor. Cancer Res 60 20 (2000) 5902-5907
17. Konturek P.C., Bielanski W., Konturek S.J., Hartwich A., Pierzchalski P., Gonciarz M., arlicz K., Starzynska T., Zuchowicz M., Darasz Z., Gotze J.P., Rehfeld J.F., and Hahn E.G. Progastrin and cyclooxygenase-2 in colorectal cancer. Dig Dis Sci 47 9 (2002) 1984-1991
18. Juttner S., Cramer T., Wessler S., Walduck A., Gao F., Schmitz F., Wunder C., Weber M., Fischer S.M., Schmidt W.E., Wiedenmann B., Meyer T.F., Naumann M., and Hocker M. Helicobacter pylori stimulates host cyclooxygenase-2 gene transcription: critical importance of MEK/ERK-dependent activation of USF1/-2 and CREB transcription factors. Cell Microbiol 5 11 (2003) 821-834
19. Wessler S., Hocker M., Fischer W., Wang T.C., Rosewicz S., Haas R., Wiedenmann B., Meyer T.F., and Naumann M. Helicobacter pylori activates the histidine decarboxylase promoter through a mitogen-activated protein kinase pathway independent of pathogenicity island-encoded virulence factors. J Biol Chem 275 5 (2000) 3629-3636
20. Kim Y., and Fischer S.M. Transcriptional regulation of cyclooxygenase-2 in mouse skin carcinoma cells. Regulatory role of CCAAT/enhancer-binding proteins in the differential expression of cyclooxygenase-2 in normal and neoplastic tissues. J Biol Chem 273 42 (1998) 27686-27694
21. Qyang Y., Luo X., Lu T., Ismail P.M., Krylov D., Vinson C., and Sawadogo M. Cell-type-dependent activity of the ubiquitous transcription factor USF in cellular proliferation and transcriptional activation. Mol Cell Biol 19 2 (1999) 1508-1517
22. Hocker M., Raychowdhury R., Plath T., Wu H., O'Connor D.T., Wiedenmann B., Rosewicz S., and Wang T.C. Sp1 and CREB mediate gastrin-dependent regulation of chromogranin A promoter activity in gastric carcinoma cells. J Biol Chem 273 51 (1998) 34000-34007
23. Hocker M., Henihan R.J., Rosewicz S., Riecken E.O., Zhang Z., Koh T.J., and Wang T.C. Gastrin and phorbol 12-myristate 13-acetate regulate the human histidine decarboxylase promoter through Raf-dependent activation of extracellular signal-regulated kinase-related signaling pathways in gastric cancer cells. J Biol Chem 272 43 (1997) 27015-27024
24. Nordeen S.K. Luciferase reporter gene vectors for analysis of promoters and enhancers. Biotechniques 6 5 (1988) 454-458
25. Smith W.L., DeWitt D.L., and Garavito R.M. Cyclooxygenases: structural, cellular, and molecular biology. Annu Rev Biochem 69 (2000) 145-182
26. Sawadogo M., and Roeder R.G. Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region. Cell 43 1 (1985) 165-175
27. Sirito M., Lin Q., Maity T., and Sawadogo M. Ubiquitous expression of the 43- and 44-kDa forms of transcription factor USF in mammalian cells. Nucleic Acids Res 22 3 (1994) 427-433
28. Fleming R.E., and Sly W.S. Hepcidin: a putative iron-regulatory hormone relevant to hereditary hemochromatosis and the anemia of chronic disease. Proc Natl Acad Sci U S A 98 15 (2001) 8160-8162
29. Vallet V.S., Casado M., Henrion A.A., Bucchini D., Raymondjean M., Kahn A., and Vaulont S. Differential roles of upstream stimulatory factors 1 and 2 in the transcriptional response of liver genes to glucose. J Biol Chem 273 32 (1998) 20175-20179
30. Jaiswal A.S., and Narayan S. Upstream stimulating factor-1 (USF1) and USF2 bind to and activate the promoter of the adenomatous polyposis coli (APC) tumor suppressor gene. J Cell Biochem 81 2 (2001) 262-277
31. Caplin M., Khan K., Grimes S., Michaeli D., Savage K., Pounder R., and Dhillon A. Effect of gastrin and anti-gastrin antibodies on proliferation of hepatocyte cell lines. Dig Dis Sci 46 7 (2001) 1356-1366
32. Smith A.M., Justin T., Michaeli D., and Watson S.A. Phase I/II study of G17-DT, an anti-gastrin immunogen, in advanced colorectal cancer. Clin Cancer Res 6 12 (2000) 4719-4724
33. Gilliam A.D., Watson S.A., Henwood M., McKenzie A.J., Humphreys J.E., Elder J., Iftikhar S.Y., Welch N., Fielding J., Broome P., and Michaeli D. A phase II study of G17DT in gastric carcinoma. Eur J Surg Oncol 30 5 (2004) 536-543