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Volumn 144, Issue 1-3, 2007, Pages 34-42

The CCK-2/gastrin splice variant receptor retaining intron 4 transactivates the COX-2 promoter in vitro

Author keywords

CCK 2i4svR; Cholecystokinin; Gastrin 17; Mitogen activated protein kinase

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ARACHIDONIC ACID; CHOLECYSTOKININ B RECEPTOR; COMPLEMENTARY DNA; CYCLOOXYGENASE 2; GASTRIN; GASTRIN RECEPTOR; LUCIFERASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROSTAGLANDIN E2;

EID: 35649019168     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.regpep.2007.05.007     Document Type: Article
Times cited : (4)

References (36)
  • 3
    • 0037073757 scopus 로고    scopus 로고
    • Gastrin stimulate scyclooxygenase-2 expression in intestinal epithelial cells through multiple signaling pathways. Evidence for involvement of ERK5 kinase and transactivation of the epidermal growth factor receptor
    • Guo Y.S., Cheng J.Z., Jin G.F., Gutkind J.S., Hellmich M.R., and Townsend Jr. C.M. Gastrin stimulate scyclooxygenase-2 expression in intestinal epithelial cells through multiple signaling pathways. Evidence for involvement of ERK5 kinase and transactivation of the epidermal growth factor receptor. J Biol Chem 277 (2002) 48755-48763
    • (2002) J Biol Chem , vol.277 , pp. 48755-48763
    • Guo, Y.S.1    Cheng, J.Z.2    Jin, G.F.3    Gutkind, J.S.4    Hellmich, M.R.5    Townsend Jr., C.M.6
  • 4
    • 0028982966 scopus 로고
    • Expression, processing, and secretion of gastrin in patients with colorectal carcinoma
    • Ciccotosto G.D., McLeish A., Hardy K.J., and Shulkes A. Expression, processing, and secretion of gastrin in patients with colorectal carcinoma. Gastroenterology 109 (1995) 1142-1153
    • (1995) Gastroenterology , vol.109 , pp. 1142-1153
    • Ciccotosto, G.D.1    McLeish, A.2    Hardy, K.J.3    Shulkes, A.4
  • 5
    • 0032788272 scopus 로고    scopus 로고
    • Antibodies raised by gastrimmune inhibit the spontaneous metastasis of a human colorectal tumour AP5LV
    • Watson S.A., Michaeli D., Morris T.M., Clarke P., Varro A., Griffin N., Smith A., and Justin T. Antibodies raised by gastrimmune inhibit the spontaneous metastasis of a human colorectal tumour AP5LV. Eur J Cancer 35 (1999) 1286-1291
    • (1999) Eur J Cancer , vol.35 , pp. 1286-1291
    • Watson, S.A.1    Michaeli, D.2    Morris, T.M.3    Clarke, P.4    Varro, A.5    Griffin, N.6    Smith, A.7    Justin, T.8
  • 6
    • 0034667445 scopus 로고    scopus 로고
    • Antiserum raised against an epitope of the cholecystokinin B/gastrin receptor inhibits hepatic invasion of a human colon tumor
    • Watson S.A., Clarke P.A., Morris T.M., and Caplin M.E. Antiserum raised against an epitope of the cholecystokinin B/gastrin receptor inhibits hepatic invasion of a human colon tumor. Cancer Res 60 (2000) 5902-5907
    • (2000) Cancer Res , vol.60 , pp. 5902-5907
    • Watson, S.A.1    Clarke, P.A.2    Morris, T.M.3    Caplin, M.E.4
  • 7
    • 0025857560 scopus 로고
    • Prostaglandin endoperoxide synthase: regulation of enzyme expression
    • DeWitt D.L. Prostaglandin endoperoxide synthase: regulation of enzyme expression. Biochim Biophys Acta 1083 (1991) 121-134
    • (1991) Biochim Biophys Acta , vol.1083 , pp. 121-134
    • DeWitt, D.L.1
  • 8
    • 0028555837 scopus 로고
    • Regulation of prostaglandin synthase-1 and prostaglandin synthase-2
    • Herschman H.R. Regulation of prostaglandin synthase-1 and prostaglandin synthase-2. Cancer Metastasis Rev 13 (1994) 241-256
    • (1994) Cancer Metastasis Rev , vol.13 , pp. 241-256
    • Herschman, H.R.1
  • 9
    • 0028959950 scopus 로고
    • Regulation of prostaglandin endoperoxide synthase (cyclooxygenase) isozyme expression
    • Goppelt-Struebe M. Regulation of prostaglandin endoperoxide synthase (cyclooxygenase) isozyme expression. Prostaglandins Leukot Essent Fat Acids 52 (1995) 213-222
    • (1995) Prostaglandins Leukot Essent Fat Acids , vol.52 , pp. 213-222
    • Goppelt-Struebe, M.1
  • 11
    • 0030952695 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential
    • Tsujii M., Kawano S., and DuBois R.N. Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential. Proc Natl Acad Sci U S A 94 (1997) 3336-3340
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 3336-3340
    • Tsujii, M.1    Kawano, S.2    DuBois, R.N.3
  • 12
    • 0033590207 scopus 로고    scopus 로고
    • The role of cyclooxygenases in inflammation, cancer, and development
    • Williams C.S., Mann M., and DuBois R.N. The role of cyclooxygenases in inflammation, cancer, and development. Oncogene 18 (1999) 7908-7916
    • (1999) Oncogene , vol.18 , pp. 7908-7916
    • Williams, C.S.1    Mann, M.2    DuBois, R.N.3
  • 13
    • 0028824312 scopus 로고
    • Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and camp response element
    • Inoue H., Yokoyama C., Hara S., Tone Y., and Tanabe T. Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and camp response element. J Biol Chem 270 (1995) 24965-24971
    • (1995) J Biol Chem , vol.270 , pp. 24965-24971
    • Inoue, H.1    Yokoyama, C.2    Hara, S.3    Tone, Y.4    Tanabe, T.5
  • 14
    • 0032538428 scopus 로고    scopus 로고
    • Transcriptional regulation of cyclooxygenase-2 in mouse skin carcinoma cells regulatory role of CCAAT/enhancer-binding proteins in the differential expression of cyclooxygenase-2 in normal and neoplastic tissues
    • Kim Y., and Fischer S.M. Transcriptional regulation of cyclooxygenase-2 in mouse skin carcinoma cells regulatory role of CCAAT/enhancer-binding proteins in the differential expression of cyclooxygenase-2 in normal and neoplastic tissues. J Biol Chem 273 (1998) 27686-27694
    • (1998) J Biol Chem , vol.273 , pp. 27686-27694
    • Kim, Y.1    Fischer, S.M.2
  • 15
    • 0028300692 scopus 로고
    • Biological actions of cholecystokinin
    • Crawley J.N., and Corwin R.L. Biological actions of cholecystokinin. Peptides 15 (1994) 731-755
    • (1994) Peptides , vol.15 , pp. 731-755
    • Crawley, J.N.1    Corwin, R.L.2
  • 16
    • 0028845124 scopus 로고
    • Cholecystokinin receptors
    • Wank S.A. Cholecystokinin receptors. Am J Physiol 269 (1995) G628-G646
    • (1995) Am J Physiol , vol.269
    • Wank, S.A.1
  • 17
    • 0031968525 scopus 로고    scopus 로고
    • G protein-coupled receptors in gastrointestinal physiology I CCK receptors: an exemplary family
    • Wank S.A. G protein-coupled receptors in gastrointestinal physiology I CCK receptors: an exemplary family. Am J Physiol 274 (1998) G607-G613
    • (1998) Am J Physiol , vol.274
    • Wank, S.A.1
  • 19
    • 0030943262 scopus 로고    scopus 로고
    • Basic amino acids at the C-terminus of the third intracellular loop are required for the activation of phospholipase C by cholecystokinin-B receptors
    • Wang H.L. Basic amino acids at the C-terminus of the third intracellular loop are required for the activation of phospholipase C by cholecystokinin-B receptors. J Neurochem 68 (1997) 1728-1735
    • (1997) J Neurochem , vol.68 , pp. 1728-1735
    • Wang, H.L.1
  • 20
    • 0032101983 scopus 로고    scopus 로고
    • G-protein-coupled receptors: turn-ons and turn-offs
    • Carman C.V., and Benovic J.L. G-protein-coupled receptors: turn-ons and turn-offs. Curr Opin Neurobiol 8 (1998) 335-344
    • (1998) Curr Opin Neurobiol , vol.8 , pp. 335-344
    • Carman, C.V.1    Benovic, J.L.2
  • 21
    • 0029719789 scopus 로고    scopus 로고
    • Desensitization of G protein-coupled receptors
    • Freedman N.J., and Lefkowitz R.J. Desensitization of G protein-coupled receptors. Recent Prog Horm Res 51 (1996) 319-351
    • (1996) Recent Prog Horm Res , vol.51 , pp. 319-351
    • Freedman, N.J.1    Lefkowitz, R.J.2
  • 22
    • 0034644655 scopus 로고    scopus 로고
    • Human colorectal cancers express a constitutively active cholecystokinin-B/gastrin receptor that stimulates cell growth
    • Hellmich M.R., Rui X.L., Hellmich H.L., Fleming R.Y., Evers B.M., and Townsend Jr. C.M. Human colorectal cancers express a constitutively active cholecystokinin-B/gastrin receptor that stimulates cell growth. J Biol Chem 275 (2000) 32122-32128
    • (2000) J Biol Chem , vol.275 , pp. 32122-32128
    • Hellmich, M.R.1    Rui, X.L.2    Hellmich, H.L.3    Fleming, R.Y.4    Evers, B.M.5    Townsend Jr., C.M.6
  • 23
    • 0035885395 scopus 로고    scopus 로고
    • Identification of CCK-2/gastrin receptor splice variants in human peripheral blood mononuclear cells
    • Schmitz F., Schrader H., Otte J., Schmitz H., Stuber E., Herzig K., and Schmidt W.E. Identification of CCK-2/gastrin receptor splice variants in human peripheral blood mononuclear cells. Regul Pept 101 (2001) 25-33
    • (2001) Regul Pept , vol.101 , pp. 25-33
    • Schmitz, F.1    Schrader, H.2    Otte, J.3    Schmitz, H.4    Stuber, E.5    Herzig, K.6    Schmidt, W.E.7
  • 24
    • 0028935974 scopus 로고
    • Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms
    • Derijard B., Raingeaud J., Barrett T., Wu I.H., Han J., Ulevitch R.J., and Davis R.J. Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms. Science Feb 3 267 5198 (1995) 682-685
    • (1995) Science Feb 3 , vol.267 , Issue.5198 , pp. 682-685
    • Derijard, B.1    Raingeaud, J.2    Barrett, T.3    Wu, I.H.4    Han, J.5    Ulevitch, R.J.6    Davis, R.J.7
  • 25
    • 0034715057 scopus 로고    scopus 로고
    • Helicobacter pylori infection and gastrin and cyclooxygenase expression in gastric and colorectal malignancies
    • Konturek S.J., Konturek P.C., Hartwich A., and Hahn E.G. Helicobacter pylori infection and gastrin and cyclooxygenase expression in gastric and colorectal malignancies. Regul Pept 93 (2000) 13-19
    • (2000) Regul Pept , vol.93 , pp. 13-19
    • Konturek, S.J.1    Konturek, P.C.2    Hartwich, A.3    Hahn, E.G.4
  • 29
    • 0034721853 scopus 로고    scopus 로고
    • Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells
    • Shao J., Sheng H., Inoue H., Morrow J.D., and DuBois R.N. Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells. J Biol Chem 275 (2000) 33951-33956
    • (2000) J Biol Chem , vol.275 , pp. 33951-33956
    • Shao, J.1    Sheng, H.2    Inoue, H.3    Morrow, J.D.4    DuBois, R.N.5
  • 31
    • 0033788750 scopus 로고    scopus 로고
    • Review article: gastrin and colorectal cancer
    • Smith A.M., and Watson S.A. Review article: gastrin and colorectal cancer. Aliment Pharmacol Ther 14 (2000) 1231-1247
    • (2000) Aliment Pharmacol Ther , vol.14 , pp. 1231-1247
    • Smith, A.M.1    Watson, S.A.2
  • 32
    • 0035043972 scopus 로고    scopus 로고
    • The gastrins: their production and biological activities
    • Dockray G.J., Varro A., Dimaline R., and Wang T. The gastrins: their production and biological activities. Annu Rev Physiol 63 (2001) 119-139
    • (2001) Annu Rev Physiol , vol.63 , pp. 119-139
    • Dockray, G.J.1    Varro, A.2    Dimaline, R.3    Wang, T.4
  • 34
    • 0026751438 scopus 로고
    • Inhibition of gastrin-stimulated growth of gastrointestinal tumour cells by octreotide and the gastrin/cholecystokinin receptor antagonists proglumide and lorglumide
    • Watson S.A., Morris D.L., Durrant L.G., Robertson J.F., and Hardcastle J.D. Inhibition of gastrin-stimulated growth of gastrointestinal tumour cells by octreotide and the gastrin/cholecystokinin receptor antagonists proglumide and lorglumide. Eur J Cancer 28A (1992) 1462-1467
    • (1992) Eur J Cancer , vol.28 A , pp. 1462-1467
    • Watson, S.A.1    Morris, D.L.2    Durrant, L.G.3    Robertson, J.F.4    Hardcastle, J.D.5
  • 35
    • 0037183676 scopus 로고    scopus 로고
    • COX-2 selective inhibition reverses the trophic properties of gastrin in colorectal cancer
    • Yao M., Song D.H., Rana B., and Wolfe M.M. COX-2 selective inhibition reverses the trophic properties of gastrin in colorectal cancer. Br J Cancer 87 (2002) 574-579
    • (2002) Br J Cancer , vol.87 , pp. 574-579
    • Yao, M.1    Song, D.H.2    Rana, B.3    Wolfe, M.M.4
  • 36
    • 0029739068 scopus 로고    scopus 로고
    • Identification of cholecystokinin-B/gastrin receptor domains that confer high gastrin affinity: utilization of a novel Xenopus laevis cholecystokinin receptor
    • Schmitz F., Pratt D.S., Wu M.J., Kolakowski Jr. L.F., Beinborn M., and Kopin A.S. Identification of cholecystokinin-B/gastrin receptor domains that confer high gastrin affinity: utilization of a novel Xenopus laevis cholecystokinin receptor. Mol Pharmacol 50 (1996) 436-441
    • (1996) Mol Pharmacol , vol.50 , pp. 436-441
    • Schmitz, F.1    Pratt, D.S.2    Wu, M.J.3    Kolakowski Jr., L.F.4    Beinborn, M.5    Kopin, A.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.