Inverted and deleted chromosome 16 with deletion of 3′ CBFB identified by fluorescence in situ hybridization

Cancer Genetics and Cytogenetics

Volumn 179, Issue 1, 2007, Pages 82-84

  Spencer, Deborah V ^a   Cavalier, MaryEllen ^a   Kalpatthi, Ram ^a   Quigley, Denise I ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABDOMINAL PAIN; ACUTE GRANULOCYTIC LEUKEMIA; BONE PAIN; CASE REPORT; CHROMOSOME 16; CHROMOSOME ANALYSIS; CHROMOSOME DELETION; CHROMOSOME INVERSION; FACE EDEMA; FATIGUE; FEVER; FLUORESCENCE IN SITU HYBRIDIZATION; FOOT EDEMA; HEPATOSPLENOMEGALY; HUMAN; LETTER; MALE; PRIORITY JOURNAL; SCHOOL CHILD;

CHILD; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 16; CORE BINDING FACTOR BETA SUBUNIT; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INVERSION, CHROMOSOME; LEUKEMIA, MONOCYTIC, ACUTE; MALE; MUTANT CHIMERIC PROTEINS; MYOSIN HEAVY CHAINS;

EID: 35649012002     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2007.08.007     Document Type: Letter

References (10)

1. Kolomietz E., Al-Maghrabi J., Brennan S., Karaskova J., Minkin S., Lipton J., and Squire J.A. Primary chromosomal rearrangements of leukemia are frequently accompanied by extensive submicroscopic deletions and may lead to altered prognosis. Blood 97 (2001) 3581-3588
2. Le Beau M.M., Larson R.A., Bitter M.A., Vardiman J.W., Golomb H.M., and Rowley J.D. Association of an inversion of chromosome 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia: a unique cytogenetic-clinicopathological association. N Engl J Med 309 (1983) 630-636
3. Liu P., Tarlé S.A., Hajra A., Claxton D.F., Marlton P., Freedman M., Siciliano M.J., and Collins F.S. Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia. Science 261 (1993) 1041-1044
4. Bloomfield C.D., Shuma C., Regal L., Philip P.P., Hossfeld D.K., Hagemeijer A.M., Garson O.M., Peterson B.A., Sakurai M., Alimena G., Berger R., Rowley J.D., Ruutu T., Mitelman F., Dewald G.W., and Swansbury J. Long-term survival of patients with acute myeloid leukemia: a third follow-up of the Fourth International Workshop on Chromosomes in Leukemia. Cancer 80 (1997) 2191-2198
5. Delaunay J., Vey N., Leblanc T., Fenaux P., Rigal-Huguet F., Witz F., Lamy T., Auvrignon A., Blaise D., Pigneux A., Mugneret F., Bastard C., Dastugue N., Van den Akker J., Fiere D., Reiffers J., Castaigne S., Leverger G., Harousseau J.L., and Dombret H. French Acute Myeloid Leukemia Intergroup; Groupe Ouest-Est des Leucémies Aigües Myeoblastiques; Leucémies Aigües Myeoblastiques de l'Enfant; Acute Leukemia French Association; Bordeaux-Grenoble-Marseille-Toulouse cooperative groups. Prognosis of inv(16)/t(16;16) acute myeloid leukemia (AML): a survey of 110 cases from the French AML Intergroup. Blood 102 (2003) 462-469
6. Batanian J.R., Huang Y., and Fallon R. Deletion of 3′-CBFB gene in association with an inversion (16)(p13q22) and a loss of the Y chromosome in a 2-year-old child with acute myelogenous leukemia-M4. Cancer Genet Cytogenet 121 (2000) 216-219
7. Egan N., O'Reilly J., Chipper L., Higgins M., Herrmann R., and Cannell P. Deletion of CBFB in a patient with acute myelomonocytic leukemia (AML M4Eo) and inversion 16. Cancer Genet Cytogenet 154 (2004) 60-62
8. Kelly J., Foot N.J., Conneally E., Enright H., Humphreys M., Saunders K., and Neat M.J. 3′ CBFβ deletion associated with inv(16) in acute myeloid leukemia. Cancer Genet Cytogenet 162 (2005) 122-126
9. Hung D., St Heaps L., Benson W., Mirochnik O., Sharma P., and Smith A. Deletion of 3′ CBFβ in an inv(16)(p13.1q22) ascertained by fluorescence in situ hybridization and reverse-transcriptase polymerase chain reaction. Cancer Genet Cytogenet 172 (2007) 92-94
10. Marlton P., Claxton D.F., Liu P., Estey E.H., Beran M., LeBeau M., Testa J.R., Collins F.S., Rowley J.D., and Siciliano M.J. Molecular characterization of 16p deletions associated with inversion 16 defines the critical fusion for leukemogenesis. Blood 85 (1995) 772-779