Synthesis and cytotoxic activity of various 5-[alkoxy-(4-nitro-phenyl)-methyl]-uracils in their racemic form

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 23, 2007, Pages 6647-6650

  Spáčilová, Lucie ^a   Džubák, Petr ^a   Hajdúch, Marián ^a   Křupková, Soňa ^a   Hradil, Pavel ^a   Hlaváč, Jan ^a  

^a PALACKÝ UNIVERSITY   (Czech Republic)

Author keywords

Anticancer activity; Apoptosis; Cytotoxic; DNA; RNA; Uracil

Indexed keywords

5 [ALKOXY (4 NITRO PHENYL) METHYL] URACIL DERIVATIVE; ALCOHOL DERIVATIVE; ETHER DERIVATIVE; UNCLASSIFIED DRUG; URACIL DERIVATIVE;

ARTICLE; BIOLOGICAL ACTIVITY; CANCER CELL CULTURE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DNA SYNTHESIS INHIBITION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG RESISTANCE; MULTIDRUG RESISTANCE; PROTEIN EXPRESSION; RACEMIZATION; RNA SYNTHESIS; SUBSTITUTION REACTION;

ALCOHOLS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CYTOTOXINS; HUMANS; K562 CELLS; STEREOISOMERISM; URACIL;

EID: 35649007378     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.09.022     Document Type: Article

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