Relative bioavailability of new formulation of paracetamol effervescent powder containing sodium bicarbonate versus paracetamol tablets: A comparative pharmacokinetic study in fed subjects

Expert Opinion on Pharmacotherapy

Volumn 8, Issue 15, 2007, Pages 2449-2457

  Di Girolamo, Guillermo ^a,g   Opezzo, Javier A W ^b   Lopez, Marcela I ^b   Schere, Daniel ^c   Keller, Guillermo ^a   Gonzalez, Claudio D ^d   Massa, Javier Martinelli ^e   de los Santos, María Cecilia ^f  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b Biochemistry Analytical Unit   (Argentina)

^c Laboratory of Clinical Tests and Nuclear Medicine Dr M Schere ^*  (Argentina)

^d CEMIC   (Argentina)

^e GSK Consumer HealthCare South America   (United States)

^f GlaxoSmithKline   (Argentina)

^g NONE   (Argentina)

Author keywords

Bioavailability; Effervescent; Paracetamol tablet; Pharmacokinetic; Sodium bicarbonate

Indexed keywords

ALIKAL DOLOR; BICARBONATE; PARACETAMOL; PARAGENIOL; UNCLASSIFIED DRUG;

ABSENCE OF SIDE EFFECTS; ADULT; AREA UNDER THE CURVE; ARTICLE; BIOEQUIVALENCE; CALIBRATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG HALF LIFE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; MALE; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; OPEN STUDY; POWDER; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; TABLET; TIME TO MAXIMUM PLASMA CONCENTRATION; VOLUNTEER;

EID: 35649002068     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.8.15.2449     Document Type: Article

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