A surface 75-kDa protein with acid phosphatase activity recognized by monoclonal antibodies that inhibit Paracoccidioides brasiliensis growth

Microbes and Infection

Volumn 9, Issue 12-13, 2007, Pages 1484-1492

  Xander, Patrícia ^a   Vigna, Ana Flávia ^a   Feitosa, Luciano dos Santos ^a   Pugliese, Lívia ^a   Bailão, Alexandre Melo ^b   Soares, Célia Maria de Almeida ^b   Mortara, Renato Arruda ^a   Mariano, Mario ^a   Lopes, José Daniel ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF GOIÁS   (Brazil)

Author keywords

Acid phosphatase; Monoclonal antibodies; P. brasiliensis

Indexed keywords

ACID PHOSPHATASE; FUNGAL PROTEIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN RECOGNITION; ARTICLE; COLONY FORMING UNIT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; FUNGUS GROWTH; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; LUNG GRANULOMA; MALE; MOUSE; NONHUMAN; PARACOCCIDIOIDES BRASILIENSIS; PASSIVE IMMUNIZATION; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; SOUTH AMERICAN BLASTOMYCOSIS;

ACID PHOSPHATASE; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, FUNGAL; FUNGAL PROTEINS; IMMUNIZATION, PASSIVE; MACROPHAGES, PERITONEAL; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PARACOCCIDIOIDES; PARACOCCIDIOIDOMYCOSIS; PHAGOCYTOSIS;

FUNGI; MURINAE; MUS; PARACOCCIDIOIDES BRASILIENSIS;

EID: 35648985135     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2007.08.001     Document Type: Article

References (30)

1. Borges-Walmsley M.I., Chen D., Shu X., and Walmsley A.R. The pathobiology of Paracoccidioides brasiliensis. Trends Microbiol. 10 (2002) 80-87
2. Vicentini A.P., Gesztesi J.L., Franco M.F., de Souza W., de Moraes J.Z., Travassos L.R., and Lopes J.D. Binding of Paracoccidioides brasiliensis to laminin through surface glycoprotein gp43 leads to enhancement of fungal pathogenesis. Infect. Immun. 62 (1994) 1465-1469
3. Mendes-Giannini M.J., Andreotti P.F., Vincenzi L.R., da Silva J.L., Lenzi H.L., Benard G., Zancope-Oliveira R., de Matos Guedes H.L., and Soares C.P. Binding of extracellular matrix proteins to Paracoccidioides brasiliensis. Microbes Infect. 8 (2006) 1550-1559
4. Taborda C.P., Juliano M.A., Puccia R., Franco M., and Travassos L.R. Mapping of the T-cell epitope in the major 43-kilodalton glycoprotein of Paracoccidioides brasiliensis which induces a Th-1 response protective against fungal infection in BALB/c mice. Infect. Immun. 66 (1998) 786-793
5. Grosso D.M., de Almeida S.R., Mariano M., and Lopes J.D. Characterization of gp70 and anti-gp70 monoclonal antibodies in Paracoccidioides brasiliensis pathogenesis. Infect. Immun. 71 (2003) 6534-6542
6. Barbosa M.S., Bao S.N., Andreotti P.F., de Faria F.P., Felipe M.S., Feitosa L.S., Mendes-Giannini M.J., and Soares C.M. Glyceraldehyde-3-phosphate dehydrogenase of Paracoccidioides brasiliensis is a cell surface protein involved in fungal adhesion to extracellular matrix proteins and interaction with cells. Infect. Immun. 74 (2006) 382-389
7. Klis F.M. Cell-wall assembly in yeast. Yeast 10 (1994) 851-869
8. Bernard M., Mouyna I., Dubreucq G., Debeaupuis J.P., Fontaine T., Vorgias C., Fuglsang C., and Latge J.P. Characterization of a cell-wall acid phosphatase (PhoAp) in Aspergillus fumigatus. Microbiology 148 (2002) 2819-2829
9. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
10. Camargo Z.P., Unterkircher C., and Travassos L.R. Identification of antigenic polypeptides of Paracoccidioides brasiliensis by immunoblotting. J. Med. Vet. Mycol. 27 (1989) 407-412
11. Travassos L.R. In: Franco M., Lacaz C.S., Restrepo A.M., and Del Negro G. (Eds). Paracoccidioidomycosis (1994), CRC Press, Boca Raton, FL 67-86
12. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
13. Lopes J.D., and Alves M.J.M. In: Morel C.M. (Ed). Genes and Parasites. A Laboratory Manual (1983), OMS, Rio de Janeiro 386-398
14. Bouvet J.P., Pires R., and Pillot J. A modified gel-filtration technique producing an unusual exclusion volume of IgM - a simple way of preparing monoclonal IgM. J. Immunol. Methods 66 (1984) 299-305
15. In: Harlow E., and Lane D. (Eds). Antibodies: A Laboratory Manual (1988), Cold Spring Harbor Laboratory, New York
16. Batista W.L., Matsuo A.L., Ganiko L., Barros T.F., Veiga T.R., Freymuller E., and Puccia R. The PbMDJ1 gene belongs to a conserved MDJ1/LON locus in thermodimorphic pathogenic fungi and encodes a heat shock protein that localizes to both the mitochondria and cell wall of Paracoccidioides brasiliensis. Eukaryotic Cell 5 (2006) 379-390
17. Soares R.M.A., Silva F.C., Rozental S., Angluster J., de Souza W., Alviano C.S., and Travassos L.R. Anionogenic groups and surface sialoglycoconjugate structures of yeast forms of the human pathogen Paracoccidioides brasiliensis. Microbiology 144 (1998) 309-314
18. Popi A.F., Lopes J.D., and Mariano M. Gp43 from Paracoccidioides brasiliensis inhibits macrophage functions. An evasion mechanism of the fungus. Cell. Immunol. 218 (2002) 87-94
19. Pick E., and Mizel D. Rapid microassay for the measurement of superoxide and hydrogen peroxide production by macrophage in culture using an automatic enzyme immunoassay reader. J. Immunol. Methods 46 (1981) 211-226
20. Singervermes L.M., Ciavaglia M.C., Kashino S.S., Burger E., and Calich V.L.G. The source of the growth-promoting factor(s) affects the plating efficiency of Paracoccidioides brasiliensis. J. Med. Vet. Mycol. 30 (1992) 261-264
21. O'Farrell P.H. High resolution two-dimensional electrophoresis of proteins. J. Biol. Chem. 250 (1975) 4007-4021
22. Kneipp L.F., Rodrigues M.L., Holandino C., Esteves F.F., Souto-Padron T., Alviano C.S., Travassos L.R., and Meyer-Fernandes J.R. Ectophosphatase activity in conidial forms of Fonsecaea pedrosoi is modulated by exogenous phosphate and influences fungal adhesion to mammalian cells. Microbiology 150 (2004) 3355-3362
23. da Fonseca C.A., Jesuino R.S.A., Felipe M.S.S., Cunha D.A., Brito W.A., and Soares C.M.A. Two-dimensional electrophoresis and characterization of antigens from Paracoccidioides brasiliensis. Microbes Infect. 3 (2001) 535-542
24. Moragues M.D., Omaetxebarria M.J., Elguezabal N., Sevilla M.J., Conti S., Polonelli L., and Ponton J. A monoclonal antibody directed against a Candida albicans cell wall mannoprotein exerts three anti-C-albicans activities. Infect. Immun. 71 (2003) 5273-5279
25. Rodrigues M.L., Travassos L.R., Miranda K.R., Franzen A.J., Rozental S., de Souza W., Alviano C.S., and Barreto-Bergter E. Human antibodies against a purified glucosylceramide from Cryptococcus neoformans inhibit cell budding and fungal growth. Infect. Immun. 68 (2000) 7049-7060
26. Dickman M.B., and Yarden O. Serine/threonine protein kinases and phosphatases in filamentious fungi. Fungal Genet. Biol. 26 (1999) 99-117
27. Reilly T.J., Baron G.S., Nano F.E., and Kuhlenschmidt M.S. Characterization and sequencing of a respiratory burst-inhibiting acid phosphatase from Francisella tularensis. J. Biol. Chem. 271 (1996) 10973-10983
28. Nosanchuck J.D., Steenberger J.N., Shi L., Deepe Jr. G.S., and Casadevall A. Antibodies to a cell surface histone-like protein protect against Histoplasma capsulatum. J. Clin. Invest. 112 (2003) 1164-1175
29. Casadevall A., Dadachova E., and Pirofski L. Passive antibody therapy for infectious diseases. Nat. Rev. Microbiol. 2 (2004) 695-703
30. Taborda C.P., and Casadevall A. CR3 (CD11b/CD18) and CR4 (CD11c/CD18) are involved in complement-independent antibody-mediated phagocytosis of Cryptococcus neoformans. Immunity 18 (2002) 791-802