Pathobiology of small invasive breast cancers without metastases (T1a/b, N0, M0): National Surgical Adjuvant Breast and Bowel Project (NSABP) protocol B-21

Cancer

Volumn 110, Issue 9, 2007, Pages 1929-1936

  Fisher, Edwin R ^a,b   Costantino, Joseph P ^a,c   Leon, Marino E ^b   Bandos, Hanna ^a,c   Palekar, Alka S ^d   Fisher, Bernard ^a,d   Wolmark, Norman ^a,b  

^a NSABP Foundation Inc   (United States)

^b ALLEGHENY GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

National Surgical Adjuvant Breast and Bowel Project (NSABP); Pathobiology; Pathology; Protocol B 21; Small breast cancers; Treatment

Indexed keywords

ESTROGEN RECEPTOR; PLACEBO; TAMOXIFEN;

ARTICLE; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FEMALE; FOLLOW UP; HIGH RISK PATIENT; HUMAN; INTRADUCTAL CARCINOMA; MAJOR CLINICAL STUDY; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME; UNIVARIATE ANALYSIS;

BREAST DISEASES; BREAST NEOPLASMS; CHEMOTHERAPY, ADJUVANT; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; MASTECTOMY, SEGMENTAL; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; RADIOTHERAPY; SELECTIVE ESTROGEN RECEPTOR MODULATORS; TAMOXIFEN; TREATMENT OUTCOME;

EID: 35648984064     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.23011     Document Type: Article

References (26)

1. Rosen PP, Groshen S, Kinne DW, Norton L. Factors influencing prognosis in node-negative breast carcinoma: analysis of 767 T1N0M0/t2N0M0 patients with long-term follow-up. J Clin Oncol. 1993;11:2090-2100.
2. Rosner D, Lane WW. Predicting recurrence in axillary-node negative breast cancer patients. Breast Cancer Res Treat. 1993;25:127-139.
3. Leitner SP, Swern AS, Weinberger D, Duncan LJ, Hutter RVP. Predictors of recurrence for patients with small (1 centimeter or less) localized breast cancer (T1a, b N0 M0). Cancer. 1995;76:2266-2274.
4. Fentiman IS, Hyland D, Chaudary MA, Gregory WM. Prognosis of patients with breast cancers up to 1 cm in diameter. Eur J Cancer. 1996;32:417-420.
5. Giuliano AE, Barth AM, Spivack B, Beitsch PD, Evans SW. Incidence and predictors of axillary metastasis in T1 carcinoma of the breast. J Am Coll Surg. 1996;183:185-189.
6. Lee AK, Loda M, Mackarem G, et al. Lymph node negative invasive breast carcinoma 1 centimeter or less in size (T1a, b N0M0). Cancer. 1997;79:761-771.
7. Meyer JS, Fahmer M, Daniel FC. Pathology and behavior of small breast carcinomas. Semin Diagn Pathol. 1999;16:257-268.
8. Mann GB, Port ER, Rizza C, Tan LK, Borgen PI, Van Zee KJ. Six year follow-up of patients with microinvasive T1a, and T1b breast carcinoma. Ann Surg Oncol. 1999;6:591-608.
9. Saiz E, Toonkel R, Poppiti RJ, Robinson MJ. Infiltrating breast carcinoma smaller than 0.5 centimeters. Is lymph node dissection necessary? Cancer. 1999;85:2206-2211.
10. Kollias J, Murphy CA, Elston CW, Ellis IO, Robertson JFR, Blamey RW. The prognosis of small primary breast cancers. Eur J Cancer. 1999;35:908-912.
11. Yiangou C, Shousa S, Sinnett HD. Primary tumor characteristics and axillary lymph node status in breast cancer. Br J Cancer. 1999;80:1974-1978.
12. Fisher ER, Gregorio RM, Fisher B, Redmond C, Vellios F, Sommers SC. The pathology of invasive breast cancer. A syllabus derived from findings of the National Surgical Adjuvant Breast Project (Protocol No. 4). Cancer. 1975;36:1-85.
13. Fisher B, Dignam J, Tan-Chiu E, et al. Prognosis and treatment of patients with breast tumors of 1 centimeter or less and negative axillary lymph nodes. J Natl Cancer Inst. 2001;93:112-120.
14. Fisher B, Bryant J, Dignam J, et al. Tamoxifen, radiation therapy or both for prevention of ipsilateral breast tumor recurrence after lumpectomy in women with invasive breast cancers of 1 centimeter or less. J Clin Oncol. 2002;20:4141-4149.
15. Fisher B, Fisher ER, Redmond C, Brown A. Tumor nuclear grade, estrogen receptor and progesterone receptor: their value alone or in combination as indicators of outcome following adjuvant therapy for breast cancer. Breast Cancer Res Treat. 1986;7:147-160.
16. Fisher ER, Sass R, Fisher B, Gregorio R, Brown R, Wickerham DL. Pathologic findings from the National Surgical Adjuvant Breast Project (Protocol 6). II. Relation of local breast recurrence to multicentricity. Cancer. 1986;57:1717-1724.
17. Fisher ER, Anderson S, Tan-Chiu E, Fisher B, Eaton L, Wolmark N. Fifteen-year prognostic discriminants for invasive breast carcinoma. National Surgical Adjuvant Breast and Bowel Project. Protocol 06. Cancer. 2001;91:1679-1687.
18. Fisher ER, Palekar AS, Kotwal N, Lipana N. A nonencapsulated sclerosing lesion of the breast. Am J Clin Pathol. 1979;71:240-246.
19. Fisher ER, Palekar AS, Sass R, Fisher B. Scar cancers: pathologic findings from the National Surgical Adjuvant Breast Project (Protocol No. 4)-IX. Breast Cancer Res Treat. 1983;3:39-59.
20. Anderson JA, Carter D, Linell F. A symposium on sclerosing duct lesion of the breast. Pathol Ann. 1986;21:145-179.
21. Tavassoli FA. Pathology of the Breast. 2nd ed. Stamford, CT: Appleton & Lange; 1999:149-156.
22. Linell F, Ljungberg O, Anderson I. Breast carcinoma: aspects of early stages, progression and related problems. Acta Pathol Microbiol Scand. 1980;88(suppl):1-233.
23. Sloane JP, Mayers MM. Carcinoma and atypical hyperplasia in radial scars and complex sclerosing lesions: importance of lesion size and patient age. Histopathology. 1993;23:225-231.
24. VanBogaert LJ. Histologic typing of breast cancer. Acta Pathol Microbiol Scand. 1980;88:415-416.
25. Tubiana M, Koscielny S. Natural history of human breast cancer: recent data and clinical implication. Breast Cancer Res Treat. 1991;18:125-140.
26. Fisher ER, Redmond C, Fisher B. A perspective concerning the relation of duration of symptoms to treatment failure in patients with breast cancer. Cancer. 1977;40:3160-3167.