메뉴 건너뛰기




Volumn 11, Issue SUPPL. 1, 2006, Pages 13-19

The role of bisphosphonates in early breast cancer

Author keywords

Adjuvant; Bisphosphonates; Bonemetastases; Ibandronate; Skeletal related event

Indexed keywords

4 HYDROXYTAMOXIFEN; BISPHOSPHONIC ACID DERIVATIVE; CLODRONIC ACID; FULVESTRANT; IBANDRONIC ACID; PACLITAXEL; PAMIDRONIC ACID; PLACEBO; ZOLEDRONIC ACID; BONE DENSITY CONSERVATION AGENT;

EID: 35648968643     PISSN: 10837159     EISSN: 1549490X     Source Type: Journal    
DOI: 10.1634/theoncologist.11-90001-13     Document Type: Conference Paper
Times cited : (22)

References (42)
  • 1
    • 0036312256 scopus 로고    scopus 로고
    • Novel approaches to the management of bone metastases in patients with breast cancer
    • Hortobagyi GN. Novel approaches to the management of bone metastases in patients with breast cancer. Semin Oncol 2002;29(suppl 11):134-144.
    • (2002) Semin Oncol , vol.29 , Issue.SUPPL. 11 , pp. 134-144
    • Hortobagyi, G.N.1
  • 2
    • 0029916052 scopus 로고    scopus 로고
    • Bisphosphonates inhibit the adhesion of breast cancer cells to bone matrices in vitro
    • van der Pluijm G, Vloedgraven H, van Beek E et al. Bisphosphonates inhibit the adhesion of breast cancer cells to bone matrices in vitro. J Clin Invest 1996;98:698-705.
    • (1996) J Clin Invest , vol.98 , pp. 698-705
    • van der Pluijm, G.1    Vloedgraven, H.2    van Beek, E.3
  • 3
    • 0142059049 scopus 로고    scopus 로고
    • Site-specific human breast cancer (MDA-MB-231) metastases in nude rats: Model characterisation and in vivo effects of ibandronate on tumour growth
    • Neudert M, Fischer C, Krempien B et al. Site-specific human breast cancer (MDA-MB-231) metastases in nude rats: model characterisation and in vivo effects of ibandronate on tumour growth. Int J Cancer 2003;107:468-477.
    • (2003) Int J Cancer , vol.107 , pp. 468-477
    • Neudert, M.1    Fischer, C.2    Krempien, B.3
  • 4
    • 0036721078 scopus 로고    scopus 로고
    • Novel antiangiogenic effects of the bisphosphonate compound zoledronic acid
    • Wood J, Bonjean K, Ruetz S et al. Novel antiangiogenic effects of the bisphosphonate compound zoledronic acid. J Pharmacol Exp Ther 2002;302:1055-1061.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 1055-1061
    • Wood, J.1    Bonjean, K.2    Ruetz, S.3
  • 5
    • 4644261592 scopus 로고    scopus 로고
    • Mechanisms of bone metastasis
    • Roodman GD. Mechanisms of bone metastasis. N Engl J Med 2004;350:1655-1664.
    • (2004) N Engl J Med , vol.350 , pp. 1655-1664
    • Roodman, G.D.1
  • 6
    • 0030879065 scopus 로고    scopus 로고
    • Mechanisms of bone metastasis
    • Mundy GR. Mechanisms of bone metastasis. Cancer 1997;80(8 suppl):1546-1556.
    • (1997) Cancer , vol.80 , Issue.8 SUPPL. , pp. 1546-1556
    • Mundy, G.R.1
  • 7
    • 0027531814 scopus 로고
    • Double-blind controlled trial of oral clodronate in patients with bone metastases from breast cancer
    • Paterson AH, Powles TJ, Kanis JA et al. Double-blind controlled trial of oral clodronate in patients with bone metastases from breast cancer. J Clin Oncol 1993;11:59-65.
    • (1993) J Clin Oncol , vol.11 , pp. 59-65
    • Paterson, A.H.1    Powles, T.J.2    Kanis, J.A.3
  • 8
    • 10544228130 scopus 로고    scopus 로고
    • Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases. Protocol 19 Aredia Breast Cancer Study Group
    • Hortobagyi GN, Theriault RL, Porter L et al. Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases. Protocol 19 Aredia Breast Cancer Study Group. N Engl J Med 1996;335:1785-1791.
    • (1996) N Engl J Med , vol.335 , pp. 1785-1791
    • Hortobagyi, G.N.1    Theriault, R.L.2    Porter, L.3
  • 9
    • 0033050818 scopus 로고    scopus 로고
    • Pamidronate reduces skeletal morbidity in women with advanced breast cancer and lytic bone lesions: A randomized, placebo-controlled trial. Protocol 18 Aredia Breast Cancer Study Group
    • Theriault RL, Lipton A, Hortobagyi GN et al. Pamidronate reduces skeletal morbidity in women with advanced breast cancer and lytic bone lesions: a randomized, placebo-controlled trial. Protocol 18 Aredia Breast Cancer Study Group. J Clin Oncol 1999; 17:846-854.
    • (1999) J Clin Oncol , vol.17 , pp. 846-854
    • Theriault, R.L.1    Lipton, A.2    Hortobagyi, G.N.3
  • 10
    • 10744233021 scopus 로고    scopus 로고
    • Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: A randomized, double-blind, multicenter, comparative trial
    • Rosen LS, Gordon D, Kaminski M et al. Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: a randomized, double-blind, multicenter, comparative trial. Cancer 2003;98:1735-1744.
    • (2003) Cancer , vol.98 , pp. 1735-1744
    • Rosen, L.S.1    Gordon, D.2    Kaminski, M.3
  • 11
    • 17144447171 scopus 로고    scopus 로고
    • Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases
    • Body JJ, Diel IJ, Lichinitser MR et al. Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases. Ann Oncol 2003;14:1399-1405.
    • (2003) Ann Oncol , vol.14 , pp. 1399-1405
    • Body, J.J.1    Diel, I.J.2    Lichinitser, M.R.3
  • 12
    • 1942501727 scopus 로고    scopus 로고
    • Oral ibandronate reduces the risk of skeletal complications in breast cancer patients with metastatic bone disease: Results from two randomised, placebo-controlled phase III studies
    • Body JJ, Diel IJ, Lichinitzer M et al. Oral ibandronate reduces the risk of skeletal complications in breast cancer patients with metastatic bone disease: results from two randomised, placebo-controlled phase III studies. Br J Cancer 2004;90:1133-1137.
    • (2004) Br J Cancer , vol.90 , pp. 1133-1137
    • Body, J.J.1    Diel, I.J.2    Lichinitzer, M.3
  • 13
    • 13844297617 scopus 로고    scopus 로고
    • Ibandronate in metastatic bone disease: A review of pre-clinical data
    • Bauss F. Body JJ. Ibandronate in metastatic bone disease: a review of pre-clinical data. Anticancer Drugs 2005;16:107-118.
    • (2005) Anticancer Drugs , vol.16 , pp. 107-118
    • Bauss, F.1    Body, J.J.2
  • 14
    • 0030826872 scopus 로고    scopus 로고
    • Bisphosphonates inhibit prostate and breast carcinoma cell adhesion to unmineralized and mineralized bone extracellular matrices
    • Boissier S, Magnetto S, Frappart L et al. Bisphosphonates inhibit prostate and breast carcinoma cell adhesion to unmineralized and mineralized bone extracellular matrices. Cancer Res 1997;57:3890-3894.
    • (1997) Cancer Res , vol.57 , pp. 3890-3894
    • Boissier, S.1    Magnetto, S.2    Frappart, L.3
  • 15
    • 0034214362 scopus 로고    scopus 로고
    • Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases
    • Boissier S, Ferreras M, Peyruchaud O et al. Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases. Cancer Res 2000;60:2949-2954.
    • (2000) Cancer Res , vol.60 , pp. 2949-2954
    • Boissier, S.1    Ferreras, M.2    Peyruchaud, O.3
  • 16
    • 0037112368 scopus 로고    scopus 로고
    • Bisphosphonates inhibit angiogenesis in vitro and testosterone-stimulated vascular regrowth in the ventral prostate in castrated rats
    • Fournier P, Boissier S, Filleur S et al. Bisphosphonates inhibit angiogenesis in vitro and testosterone-stimulated vascular regrowth in the ventral prostate in castrated rats. Cancer Res 2002;62:6538-6544.
    • (2002) Cancer Res , vol.62 , pp. 6538-6544
    • Fournier, P.1    Boissier, S.2    Filleur, S.3
  • 17
    • 0041843917 scopus 로고    scopus 로고
    • Bisphosphonates antagonise bone growth factors' effects on human breast cancer cells survival
    • Fromigue O, Kheddoumi N, Body JJ. Bisphosphonates antagonise bone growth factors' effects on human breast cancer cells survival. Br J Cancer 2003;89:178-184.
    • (2003) Br J Cancer , vol.89 , pp. 178-184
    • Fromigue, O.1    Kheddoumi, N.2    Body, J.J.3
  • 18
    • 0034107048 scopus 로고    scopus 로고
    • Bisphosphonates induce apoptosis in human breast cancer cell lines
    • Senaratne SG, Pirianov G, Mansi JL et al. Bisphosphonates induce apoptosis in human breast cancer cell lines. Br J Cancer 2000;82:1459-1468.
    • (2000) Br J Cancer , vol.82 , pp. 1459-1468
    • Senaratne, S.G.1    Pirianov, G.2    Mansi, J.L.3
  • 19
    • 0035360867 scopus 로고    scopus 로고
    • The bisphosphonate ibandronate promotes apoptosis in MDA-MB-231 human breast cancer cells in bone metastases
    • Hiraga T, Williams PJ, Mundy GR et al. The bisphosphonate ibandronate promotes apoptosis in MDA-MB-231 human breast cancer cells in bone metastases. Cancer Res 2001;61:4418-4424.
    • (2001) Cancer Res , vol.61 , pp. 4418-4424
    • Hiraga, T.1    Williams, P.J.2    Mundy, G.R.3
  • 20
    • 0035917560 scopus 로고    scopus 로고
    • The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: Evidence for synergy with paclitaxel
    • Jagdev SP, Coleman RE, Shipman CM et al. The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: evidence for synergy with paclitaxel. Br J Cancer 2001;84:1126-1134.
    • (2001) Br J Cancer , vol.84 , pp. 1126-1134
    • Jagdev, S.P.1    Coleman, R.E.2    Shipman, C.M.3
  • 21
    • 33646107396 scopus 로고    scopus 로고
    • Mechanisms of the synergistic interaction between the bisphosphonate zoledronic acid and the chemotherapy agent paclitaxel in breast cancer cells in vitro
    • Neville-Webbe HL, Evans CA, Coleman RE et al. Mechanisms of the synergistic interaction between the bisphosphonate zoledronic acid and the chemotherapy agent paclitaxel in breast cancer cells in vitro. Tumour Biol 2006;27:92-103.
    • (2006) Tumour Biol , vol.27 , pp. 92-103
    • Neville-Webbe, H.L.1    Evans, C.A.2    Coleman, R.E.3
  • 22
    • 0032881209 scopus 로고    scopus 로고
    • Additive antitumor activities of taxoids in combination with the bisphosphonate ibandronate against invasion and adhesion of human breast carcinoma cells to bone
    • Magnetto S, Boissier S, Delmas PD et al. Additive antitumor activities of taxoids in combination with the bisphosphonate ibandronate against invasion and adhesion of human breast carcinoma cells to bone. Int I Cancer 1999;83:263-269.
    • (1999) Int I Cancer , vol.83 , pp. 263-269
    • Magnetto, S.1    Boissier, S.2    Delmas, P.D.3
  • 23
    • 33646368015 scopus 로고    scopus 로고
    • JourneF, Chaboteaux C, Magne N et al. Additive growth inhibitory effects of ibandronate and antiestrogens in estrogen receptor-positive breast can cer cell lines. Breast Cancer Res 2005;8:R2.Epub 2005 Dec 12.
    • JourneF, Chaboteaux C, Magne N et al. Additive growth inhibitory effects of ibandronate and antiestrogens in estrogen receptor-positive breast can cer cell lines. Breast Cancer Res 2005;8:R2.Epub 2005 Dec 12.
  • 24
    • 0032491037 scopus 로고    scopus 로고
    • Reduction in new metastases in breast cancer with adjuvant clodronate treatment
    • Diel IJ, Solomayer EF, Costa SD et al. Reduction in new metastases in breast cancer with adjuvant clodronate treatment. N Engl J Med 1998;339:357-363.
    • (1998) N Engl J Med , vol.339 , pp. 357-363
    • Diel, I.J.1    Solomayer, E.F.2    Costa, S.D.3
  • 25
    • 5444270251 scopus 로고    scopus 로고
    • Adjuvant clodronate treatment improves the overall survival of primary breast cancer patients with micrometastases to bone marrow - a longtime follow-up
    • Jaschke A, Bastert G, Solomayer EF et al. Adjuvant clodronate treatment improves the overall survival of primary breast cancer patients with micrometastases to bone marrow - a longtime follow-up. Proc Am Soc Clin Oncol 2004;23:9.
    • (2004) Proc Am Soc Clin Oncol , vol.23 , pp. 9
    • Jaschke, A.1    Bastert, G.2    Solomayer, E.F.3
  • 26
    • 0035148170 scopus 로고    scopus 로고
    • Adjuvant clodronate treatment does not reduce the frequency of skeletal metastases in node-positive breast cancer patients: 5-year results of a randomized controlled trial
    • Saarto T, Blomqvist C, Virkkunen P et al. Adjuvant clodronate treatment does not reduce the frequency of skeletal metastases in node-positive breast cancer patients: 5-year results of a randomized controlled trial. J Clin Oncol 2001;19:10-17.
    • (2001) J Clin Oncol , vol.19 , pp. 10-17
    • Saarto, T.1    Blomqvist, C.2    Virkkunen, P.3
  • 27
    • 0036682211 scopus 로고    scopus 로고
    • Randomized, placebo-controlled trial of clodronate in patients with primary operable breast cancer
    • Powles T, Paterson S. Kanis JA et al. Randomized, placebo-controlled trial of clodronate in patients with primary operable breast cancer. J Clin Oncol 2002;20:3219-3224.
    • (2002) J Clin Oncol , vol.20 , pp. 3219-3224
    • Powles, T.1    Paterson, S.2    Kanis, J.A.3
  • 28
    • 5444261570 scopus 로고    scopus 로고
    • Oral clodronate for adjuvant treatment of operable breast cancer: Results of a randomized, double-blind, placebo-controlled multicenter trial
    • Powles T, Paterson A, McCloskey E et al. Oral clodronate for adjuvant treatment of operable breast cancer: results of a randomized, double-blind, placebo-controlled multicenter trial. Proc Am Soc Clin Oncol 2004;23:9.
    • (2004) Proc Am Soc Clin Oncol , vol.23 , pp. 9
    • Powles, T.1    Paterson, A.2    McCloskey, E.3
  • 29
    • 13844282536 scopus 로고    scopus 로고
    • Adjuvant pamidronate (PMT) therapy for the prevention of bone metastasis in breast cancer (BC) patients (pts) with four or more positive nodes
    • Kokufu I, Kohno N, Takao S etal. Adjuvant pamidronate (PMT) therapy for the prevention of bone metastasis in breast cancer (BC) patients (pts) with four or more positive nodes. Proc Am Soc Clin Oncol 2004;23:9.
    • (2004) Proc Am Soc Clin Oncol , vol.23 , pp. 9
    • Kokufu, I.1    Kohno, N.2    Takao, S.3
  • 30
    • 22344455489 scopus 로고    scopus 로고
    • Randomized, open label, prospective study on the effect of zoledronic acid on the prevention of bone metastases in patients with recurrent solid tumors that did not present with bone metastases at baseline
    • Mystakidou K, Katsouda E, Parpa E et al. Randomized, open label, prospective study on the effect of zoledronic acid on the prevention of bone metastases in patients with recurrent solid tumors that did not present with bone metastases at baseline. Med Oncol 2005;22:195-201.
    • (2005) Med Oncol , vol.22 , pp. 195-201
    • Mystakidou, K.1    Katsouda, E.2    Parpa, E.3
  • 31
    • 9444254706 scopus 로고    scopus 로고
    • Ten-year follow-up of a randomized controlled trial of adjuvant clodronate treatment in node-positive breast cancer patients
    • Saarto T, Vehmanen L, Virkkunen P et al. Ten-year follow-up of a randomized controlled trial of adjuvant clodronate treatment in node-positive breast cancer patients. Acta Oncol 2004;43:650-656.
    • (2004) Acta Oncol , vol.43 , pp. 650-656
    • Saarto, T.1    Vehmanen, L.2    Virkkunen, P.3
  • 32
    • 0001591893 scopus 로고    scopus 로고
    • Bisphosphonates in the reduction of metastases in breast cancer-results of the extended follow-up of the first study population
    • Diel IJ, Solomayer E, Gollan C et al. Bisphosphonates in the reduction of metastases in breast cancer-results of the extended follow-up of the first study population. Proc Am Soc Clin Oncol 2000;19:82a.
    • (2000) Proc Am Soc Clin Oncol , vol.19
    • Diel, I.J.1    Solomayer, E.2    Gollan, C.3
  • 33
    • 43449084277 scopus 로고    scopus 로고
    • S0307: A phase III trial of bisphosphonates as adjuvant therapy for primary breast cancer
    • Gralow J, Paterson A. S0307: a phase III trial of bisphosphonates as adjuvant therapy for primary breast cancer. Bone 2006;38(suppl 1):S74.
    • (2006) Bone , vol.38 , Issue.SUPPL. 1
    • Gralow, J.1    Paterson, A.2
  • 34
    • 0025740255 scopus 로고
    • Tolerability and safety of clodronate therapy in bone diseases
    • Mian M. Beghe F, Caprio A et al. Tolerability and safety of clodronate therapy in bone diseases. Int J Clin Pharmacol Res 1991;11:107-114.
    • (1991) Int J Clin Pharmacol Res , vol.11 , pp. 107-114
    • Mian, M.1    Beghe, F.2    Caprio, A.3
  • 35
    • 0029166436 scopus 로고    scopus 로고
    • Robertson AG, Reed NS, Ralston SH. Effect of oral clodronate on metastatic bone pain: a double-blind, placebo-controlled study. I Clin Oncol 1995;13:2427-2430.
    • Robertson AG, Reed NS, Ralston SH. Effect of oral clodronate on metastatic bone pain: a double-blind, placebo-controlled study. I Clin Oncol 1995;13:2427-2430.
  • 36
    • 0346021648 scopus 로고    scopus 로고
    • Risk reductions in metastatic breast cancer: Multivariate Poisson regression analyses of oral and i.v. ibandronate
    • Body JJ, Kanis J, Diel I et al. Risk reductions in metastatic breast cancer: multivariate Poisson regression analyses of oral and i.v. ibandronate. Proc Am Soc Clin Oncol 2003;22:46.
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 46
    • Body, J.J.1    Kanis, J.2    Diel, I.3
  • 37
    • 2642554905 scopus 로고    scopus 로고
    • Assessing the efficacy of ibandronate for the prevention of skeletal-related events (SREs) in metastatic bone disease: A methodological comparison
    • Tripathy D, Budde M. Assessing the efficacy of ibandronate for the prevention of skeletal-related events (SREs) in metastatic bone disease: a methodological comparison. Bone 2004;34(suppl 1):S91.
    • (2004) Bone , vol.34 , Issue.SUPPL. 1
    • Tripathy, D.1    Budde, M.2
  • 38
    • 0142025453 scopus 로고    scopus 로고
    • Renal failure with the use of zoledronic acid
    • Chang JT, Green L, Beitz J. Renal failure with the use of zoledronic acid. N Engl J Med 2003;349:1676-1679.
    • (2003) N Engl J Med , vol.349 , pp. 1676-1679
    • Chang, J.T.1    Green, L.2    Beitz, J.3
  • 39
    • 2442632246 scopus 로고    scopus 로고
    • Significant deterioration in renal function with the new bisphosphonate. zoledronic acid
    • Johnson KB, Gable P, Kaime EM et al. Significant deterioration in renal function with the new bisphosphonate. zoledronic acid. Proc Am Soc Clin Oncol 2003;22:46.
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 46
    • Johnson, K.B.1    Gable, P.2    Kaime, E.M.3
  • 40
    • 20544464439 scopus 로고    scopus 로고
    • Bisphosphonate-associated osteonecrosis of mandibular and maxillary bone. An emerging oral complication of supportive cancer therapy
    • Migliorati CA, Schubert MM, Peterson DE et al. Bisphosphonate-associated osteonecrosis of mandibular and maxillary bone. An emerging oral complication of supportive cancer therapy. Cancer 2005;104:83-93.
    • (2005) Cancer , vol.104 , pp. 83-93
    • Migliorati, C.A.1    Schubert, M.M.2    Peterson, D.E.3
  • 41
    • 33644841755 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: Incidence and risk factors
    • Bamias A, Kastritis E, Bamia C et al. Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: incidence and risk factors. J Clin Oncol 2005;23:8580-8587.
    • (2005) J Clin Oncol , vol.23 , pp. 8580-8587
    • Bamias, A.1    Kastritis, E.2    Bamia, C.3
  • 42
    • 5644255147 scopus 로고    scopus 로고
    • Zoledronic acid is being investigated for the prevention of bone metastases in patients with early stage breast cancer
    • Coleman R, Gralow J, Bell R et al. Zoledronic acid is being investigated for the prevention of bone metastases in patients with early stage breast cancer. Bone 2004;34(suppl 1):S85.
    • (2004) Bone , vol.34 , Issue.SUPPL. 1
    • Coleman, R.1    Gralow, J.2    Bell, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.