Stereoselective synthesis and cytotoxicity of a cancer chemopreventive naphthoquinone from Tabebuia avellanedae

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 23, 2007, Pages 6417-6420

  Yamashita, Mitsuaki ^a   Kaneko, Masafumi ^a   Iida, Akira ^a   Tokuda, Harukuni ^b   Nishimura, Katsumi ^c  

^a TAKASAKI UNIVERSITY OF HEALTH AND WELFARE   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Antitumor activity; Cancer chemoprevention; Naphtho 2,3 b furan 4,9 dione; Stereoselective synthesis; Tabebuia avellanedae

Indexed keywords

5 HYDROXY 2 (1' HYDROXYETHYL)NAPHTHO[2,3 B]FURAN 4,9 DIONE; BETA LAPACHONE; LAPACHOL; MITOMYCIN; NAPHTHOQUINONE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; STEREOCHEMISTRY; TABEBUIA; TABEBUIA AVELLANEDAE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; HUMANS; MOLECULAR CONFORMATION; NAPHTHOQUINONES; PLANT EXTRACTS; TABEBUIA;

TABEBUIA AVELLANEDAE;

EID: 35648962898     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.10.005     Document Type: Article

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