Thiosulfinates modulate platelet activation by reaction with surface free sulfhydryls and internal thiol-containing proteins

Platelets

Volumn 18, Issue 7, 2007, Pages 481-490

  Badol, Perrine ^a   David Dufilho, Monique ^a   Auger, Jacques ^b   Whiteheart, Sidney W ^c   Rendu, Francine ^a,d  

^a SORBONNE UNIVERSITÉ   (France)

^b UNIVERSITÉ DE TOURS   (France)

^c UNIVERSITY OF KENTUCKY   (United States)

^d HÔPITAL BROUSSAIS   (France)

Author keywords

Calcium signals; Calpain; Free sulfhydryls; Platelets; Thiosulfinates

Indexed keywords

ALPHA2 INTEGRIN; ANTITHROMBOCYTIC AGENT; CALCIUM; CALPAIN; CYSTEINE; GLUTATHIONE; PROTEIN DISULFIDE ISOMERASE; SYNAPTOSOMAL ASSOCIATED PROTEIN 23; THIOL DERIVATIVE; THIOSULFINATE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG INHIBITION; DRUG MECHANISM; ENZYME ACTIVITY; HUMAN; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; THROMBOCYTE MEMBRANE;

BLOOD PLATELETS; CALCIUM; CALPAIN; FREE RADICAL SCAVENGERS; HUMANS; PLATELET ACTIVATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; SULFHYDRYL COMPOUNDS; THIOSULFONIC ACIDS;

ALLIUM;

EID: 35648957248     PISSN: 09537104     EISSN: 13691635     Source Type: Journal    
DOI: 10.1080/09537100701271828     Document Type: Article

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