A randomized, double-blind, four-arm parallel-group, placebo-controlled Phase II/III study to investigate the clinical efficacy of two galenic formulations of Polyphenon® E in the treatment of external genital warts

Journal of the European Academy of Dermatology and Venereology

Volumn 21, Issue 10, 2007, Pages 1404-1412

  Gross, Gerd ^a,c   Meyer, K G ^a   Pres, H ^a   Thielert, C ^b   Tawfik, H ^b   Mescheder, A ^b  

^a Private Practice   (Germany)

^b MediGene AG   (Germany)

^c UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

Antioxidant; Antitumour; Catechins; Genital warts; Green tea; Human comparative study; Topical

Indexed keywords

ANTIVIRUS AGENT; PLACEBO; PODOPHYLLOTOXIN; POLYPHENON E; UNCLASSIFIED DRUG;

ABNORMAL LABORATORY RESULT; ADULT; AGED; ARTICLE; BLOOD PRESSURE; BODY TEMPERATURE; CLINICAL TRIAL; CONDYLOMA; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREAM; CURETTAGE; DESICCATION; DOUBLE BLIND PROCEDURE; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG FATALITY; DRUG HYPERSENSITIVITY; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; ERYTHEMA; FEMALE; GENITAL PRURITUS; GERMANY; HEART RATE; HUMAN; HYPERKERATOSIS; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OINTMENT; PATIENT COMPLIANCE; PHASE 2 CLINICAL TRIAL; PHASE 3 CLINICAL TRIAL; PHYSICAL EXAMINATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RECURRENT VIRUS INFECTION; RESPIRATORY TRACT INFECTION; RUSSIAN FEDERATION; SIDE EFFECT; SKIN ALLERGY; SKIN BURNING SENSATION; SKIN DISCOLORATION; SKIN INFECTION; SKIN NECROSIS; SKIN PAIN; VULVITIS;

ADOLESCENT; ADULT; AGED; CATECHIN; CONDYLOMATA ACUMINATA; DOUBLE-BLIND METHOD; FEMALE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; OINTMENTS; PLACEBOS; PROGNOSIS; STATISTICS, NONPARAMETRIC; TREATMENT OUTCOME;

EID: 35648950509     PISSN: 09269959     EISSN: 14683083     Source Type: Journal    
DOI: 10.1111/j.1468-3083.2007.02441.x     Document Type: Article

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