3-O-methyldopamine (3-O-methoxytyramine) interferes with the internal standard 3,4-dihydroxybenzylamine in a plasma catecholamine HPLC method [1]

Clinical Chemistry

Volumn 53, Issue 11, 2007, Pages 1976-1977

  Pfäfflin, Albrecht ^a   Schleicher, Erwin ^a   Müssig, Karsten ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

3 O METHYLDOPAMINE; 3,4 DIHYDROXYBENZYLAMINE; CATECHOLAMINE; DOPAMINE;

ACCURACY; ARTIFACT; CATECHOLAMINE BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LETTER; PHEOCHROMOCYTOMA; PLASMA; STANDARD;

CATECHOLAMINES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYEPINEPHRINE; DOPAMINE; FALSE POSITIVE REACTIONS; HUMANS;

EID: 35648936913     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2007.094276     Document Type: Letter

References (5)

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2. Weicker H, Feraudi M, Hagele H, Pluto R. Electrochemical detection of catecholamines in urine and plasma after separation with HPLC. Clin Chim Acta 1984;141:17-25.
3. Axelrod J, Senoh S, Witkop B. O-Methylation of catechol amines in vivo. J Biol Chem 1958;233:697-701.
4. van Laarhoven HW, Willemsen JJ, Ross HA, Beex LV, Lenders JW, Sweep FC. Pitfall in HPLC assay for urinary metanephrines: an unusual type of interference caused by methenamine intake. Clin Chem 2004;50:1097-9.
5. Müssig K, Pfäfflin A, Häring HU, Schleicher E. Dipyrone (metamizole) metabolites interfere with HPLC analysis of plasma catecholamines but not with the determination of urinary catecholamines. Clin Chem 2006;52:1829-31.