Rapid detection of the DPYD IVS14+1G>A mutation for screening patients to prevent fluorouracil-related toxicity [1]

Molecular Diagnosis and Therapy

Volumn 11, Issue 5, 2007, Pages 341-

  Lazar, Andreas ^a   Gründemann, Dirk ^a   Schömig, Edgar ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Diagnostics; Fluorouracil, adverse reactions; Genetic polymorphism; Genotyping

Indexed keywords

DIHYDROPYRIMIDINE DEHYDROGENASE; FLUOROPYRIMIDINE;

CANCER CHEMOTHERAPY; COST EFFECTIVENESS ANALYSIS; DNA SEQUENCE; ENZYME ACTIVITY; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; LETTER; MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SCREENING;

EID: 35548993299     PISSN: 11771062     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03256255     Document Type: Letter

References (2)

1. Bosch TM, Bakker R, Schellens JH, et al. Rapid detection of the DPYD IV-S14+ 1G>A mutation for screening patients to prevent fluorouracil-related toxicity. Mol Diagn Ther 2007; 11 (2): 105-8
2. Lazar A, Weissenborn JS, Gründemann D, et al. Detection of a novel 1905C>T mutation within the dihydropyrimidine dehydrogenase gene and potential for misclassification with the exon 14-skipping mutation. Clin Chem 2003; 49 (4): 707-8