Dynamics of C-reactive protein and white blood cell count in critically ill patients with nosocomial Gram positive vs. Gram negative bacteremia: A historical cohort study

BMC Infectious Diseases

Volumn 7, Issue , 2007, Pages

  Vandijck, Dominique M ^a,b   Hoste, Eric A ^a,b   Blot, Stijn I ^a,b   Depuydt, Pieter O ^a   Peleman, Renaat A ^a   Decruyenaere, Johan M ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b UNIVERSITY COLLEGE GHENT   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BIOLOGICAL MARKER; C REACTIVE PROTEIN;

ADULT; AGED; APACHE; ARTICLE; BACTEREMIA; BACTERIAL INFECTION; CONTROLLED STUDY; CRITICALLY ILL PATIENT; DISEASE MARKER; EARLY INTERVENTION; FEMALE; GRAM NEGATIVE SEPSIS; HOSPITAL INFECTION; HUMAN; INTENSIVE CARE; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; PROGNOSIS; PROTEIN BLOOD LEVEL; QUANTITATIVE ANALYSIS; BLOOD; COHORT ANALYSIS; CRITICAL ILLNESS; CROSS INFECTION; GRAM NEGATIVE INFECTION; INTENSIVE CARE UNIT; METABOLISM; MICROBIOLOGY; MIDDLE AGED;

ADULT; AGED; APACHE; BACTEREMIA; C-REACTIVE PROTEIN; COHORT STUDIES; CRITICAL ILLNESS; CROSS INFECTION; FEMALE; GRAM-NEGATIVE BACTERIAL INFECTIONS; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; INTENSIVE CARE UNITS; LEUKOCYTE COUNT; MALE; MIDDLE AGED;

EID: 35548984365     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-7-106     Document Type: Article

References (27)

1. Vincent JL Microbial resistance: Lessons from the EPIC study. European Prevalence of Infection Intensive Care Med 2000, 26 Suppl 1:S3-8. 10.1007/s001340051111 10786951
2. Calandra T Cohen J The international sepsis forum consensus conference on definitions of infection in the intensive care unit Crit Care Med 2005, 33(7):1538-1548. 10.1097/01.CCM.0000168253.91200.83 16003060
3. Levy MM Fink MP Marshall JC Abraham E Angus D Cook D Cohen J Opal SM Vincent JL Ramsay G 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference Crit Care Med 2003, 31(4):1250-1256. 10.1097/ 01.CCM.0000050454.01978.3B 12682500
4. Vincent JL Sakr Y Sprung CL Ranieri VM Reinhart K Gerlach H Moreno R Carlet J Le Gall JR Payen D Sepsis in European intensive care units: results of the SOAP study Crit Care Med 2006, 34(2):344-353. 10.1097/ 01.CCM.0000194725.48928.3A 16424713
5. Vandijck D Decruyenaere JM Blot SI The value of sepsis definitions in daily ICU-practice Acta Clin Belg 2006, 61(5):220-226. 17240735
6. Povoa P Coelho L Almeida E Fernandes A Mealha R Moreira P Sabino H C-reactive protein as a marker of infection in critically ill patients Clin Microbiol Infect 2005, 11(2):101-108. 10.1111/ j.1469-0691.2004.01044.x 15679483
7. Sprung CL Sakr Y Vincent JL Le Gall JR Reinhart K Ranieri VM Gerlach H Fielden J Groba CB Payen D An evaluation of systemic inflammatory response syndrome signs in the Sepsis Occurrence in Acutely ill Patients (SOAP) study Intensive Care Med 2006, 32(3):421-427. 10.1007/ s00134-005-0039-8 16479382
8. Spapen HD Hachimi-Idrissi S Corne L Huyghens LP Diagnostic markers of sepsis in the emergency department Acta Clin Belg 2006, 61(3):138-142. 16881563
9. Kollef M Appropriate empirical antibacterial therapy for nosocomial infections: Getting it right the first time Drugs 2003, 63(20):2157-2168. 10.2165/00003495-200363200-00001 14498753
10. Martin MA Pfaller MA Wenzel RP Coagulase-negative staphylococcal bacteremia. Mortality and hospital stay Ann Intern Med 1989, 110(1):9-16. 2908834
11. Hoste EA Vandijck DM Van Holder RC De Waele JJ Lameire NH Claus S De Schuijmer J Dhondt AW Decruyenaere JM Verschraegen G Blot SI Health Implications of Antimicrobial-Resistance in Bloodstream Infection Patients with Acute Kidney Injury Infect Control Hosp Epidemiol 2007, 28(9):1107-1110. 10.1086/520100
12. Blot S Vandewoude K De Bacquer D Colardyn F Nosocomial bacteremia caused by antibiotic-resistant gram-negative bacteria in critically ill patients: Clinical outcome and length of hospitalization Clin Infect Dis 2002, 34(12):1600-1606. 10.1086/340616 12032895
13. Hoste EA Blot SI Lameire NH Vanholder RC De Bacquer D Colardyn FA Effect of nosocomial bloodstream infection on the outcome of critically ill patients with acute renal failure treated with renal replacement therapy J Am Soc Nephrol 2004, 15(2):454-462. 10.1097/01.ASN.0000110182.14608.0C 14747393
14. Myny D Depuydt P Colardyn F Blot S Ventilator-associated pneumonia in a tertiary care ICU: Analysis of risk factors for acquisition and mortality Acta Clin Belg 2005, 60(3):114-121. 16156370
15. Iregui M Ward S Sherman G Fraser VJ Kollef MH Clinical importance of delays in the initiation of appropriate antibiotic treatment for ventilator-associated pneumonia Chest 2002, 122(1):262-268. 10.1378/ chest.122.1.262 12114368
16. Kollef MH Sherman G Ward S Fraser VJ Inadequate antimicrobial treatment of infections: A risk factor for hospital mortality among critically ill patients Chest 1999, 115(2):462-474. 10.1378/chest.115.2.462 10027448
17. Kollef MH Ward S Sherman G Prentice D Schaiff R Huey W Fraser VJ Inadequate treatment of nosocomial infections is associated with certain empiric antibiotic choices Crit Care Med 2000, 28(10):3456-3464. 10.1097/ 00003246-200010000-00014 11057801
18. Leibovici L Shraga I Drucker M Konigsberger H Samra Z Pitlik SD The benefit of appropriate empirical antibiotic treatment in patients with bloodstream infection J Intern Med 1998, 244(5):379-386. 10.1046/ j.1365-2796.1998.00379.x 9845853
19. Colardyn F Appropriate and timely empirical antimicrobial treatment of icu infections - a role for carbapenems Acta Clin Belg 2005, 60(2):51-62. 16082989
20. Blot S Vandewoude K Early detection of systemic infections Acta Clin Belg 2004, 59(1):20-23. 15065692
21. Luzzani A Polati E Dorizzi R Rungatscher A Pavan R Merlini A Comparison of procalcitonin and C-reactive protein as markers of sepsis Crit Care Med 2003, 31(6):1737-1741. 10.1097/01.CCM.0000063440.19188.ED 12794413
22. Reny JL Vuagnat A Ract C Benoit MO Safar M Fagon JY Diagnosis and follow-up of infections in intensive care patients: Value of C-reactive protein compared with other clinical and biological variables Crit Care Med 2002, 30(3):529-535. 10.1097/00003246-200203000-00006 11990910
23. McCabe RE Remington JS C-reactive protein in patients with bacteremia J Clin Microbiol 1984, 20(3):317-319. 271320 6490822
24. Bone RC Balk RA Cerra FB Dellinger RP Fein AM Knaus WA Schein RM Sibbald WJ Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine Chest 1992, 101(6):1644-1655. 1303622
25. Povoa P Coelho L Almeida E Fernandes A Mealha R Moreira P Sabino H Pilot study evaluating C-reactive protein levels in the assessment of response to treatment of severe bloodstream infection Clin Infect Dis 2005, 40(12):1855-1857. 10.1086/430382 15909277
26. Byl B Deviere J Saint-Hubert F Zech F Gulbis B Thys JP Evaluation of tumor necrosis factor-alpha, interleukin-6 and C-reactive protein plasma levels as predictors of bacteremia in patients presenting signs of sepsis without shock Clin Microbiol Infect 1997, 3(3):306-316. 11864125
27. Kollef MH Inadequate antimicrobial treatment: An important determinant of outcome for hospitalized patients Clin Infect Dis 2000, 31 Suppl 4:S131-8. 10.1086/314079 11017862