Usnea barbata extract prevents ultraviolet-B induced prostaglandin E2 synthesis and COX-2 expression in HaCaT keratinocytes

Journal of Photochemistry and Photobiology B: Biology

Volumn 89, Issue 1, 2007, Pages 9-14

  Engel, K ^a   Schmidt, U ^a   Reuter, J ^a   Weckesser, S ^a   Simon Haarhaus, B ^a   Schempp, C M ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Cyclooxygenase 2; HaCaT keratinocytes; Prostaglandin E2; Ultraviolet B; Usnic acid

Indexed keywords

CYCLOOXYGENASE 2; PLANT EXTRACT; PROSTAGLANDIN E2; UNCLASSIFIED DRUG; USNEA BARBATA EXTRACT; USNIC ACID;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; KERATINOCYTE; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; PROTECTION; PROTEIN EXPRESSION; SKIN INFLAMMATION; ULTRAVIOLET B RADIATION; UPREGULATION; USNEA;

CELL EXTRACTS; CELLS, CULTURED; CYCLOOXYGENASE 2; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, ENZYMOLOGIC; KERATINOCYTES; ULTRAVIOLET RAYS; UP-REGULATION; USNEA;

USNEA BARBATA;

EID: 35548980013     PISSN: 10111344     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jphotobiol.2007.08.002     Document Type: Article

References (26)

1. Barnes J. Pharmacognosy in the 21st century. Pharm. J. 264 (2000) 701-703
2. Honegger R. Functional aspects of the lichen symbiosis. Ann. Rev. Plant Physiol. Plant Mol. Biol. 42 (1991) 553-578
3. Kjeldsen C. Mycology - Biology 339 Sonoma State University (1997), Custom Academy Publishing Company (CAPCO), Oklahoma City, OK pp. 23-32
4. Ingolfsdottir K. Usnic acid. Phytochemistry 61 (2002) 729-736
5. Huneck S. The significance of lichens and their metabolites. Naturwissenschaften 86 (1999) 559-570
6. Lauterwein M., Oethinger M., Belsner K., Peters T., and Marre R. In vitro activities of the lichen secondary metabolites vulpinic acid, (+)-usnic acid and (-)-usnic acid against aerobic and anaerobic microorganisms. Antimicrob. Agents Chemother. 39 (1995) 2541-2543
7. Rowe G.J., Gimenez G.M.D., and Rodriguez S.M.T. Some lichen products have antimicrobial activity. Z. Naturforsch. 54 (1999) 605-609
8. Cocchietto M., Skert N., Nimis P.L., and Sava G. A review on usnic acid, an interesting natural compound. Naturwissenschaften 89 (2002) 137-146
9. Weckesser S., Engel K., Simon-Haarhaus B., Wittmer A., Pelz K., and Schempp C.M. Screening of plant extracts for antimicrobial activity against bacteria and yeasts with dermatological relevance. Phytomedicine 14 (2007) 508-516
10. Kumar S., and Müller K. Lichen metabolites. 2. Antiproliferative and cytotoxic activity of gyrophoric, usnic and diffractaic acid in human keratinocyte growth. J. Nat. Prod. 62 (1999) 821-823
11. Cardarelli M., Serino G., Campanella L., Ercole P., De Cicco Nardone F., Alesiani O., and Rossiello F. Antimitotic effects of usnic acid on different biological systems. Cell. Mol. Life Sci. 53 (1997) 667-672
12. Okuyama E., Umeyama K., Yamazaki M., Kinoshita Y., and Yamamoto Y. Usnic acid and diffractaic acid as analgesic and antipyretic components of usnea diffracta. Planta Med. 61 (1995) 113-115
13. Vijayakumar C.S., Viswanathan S., Kannappa-Reddy M., Parvathavarthini S., Kundu A.B., and Sukumar E. Anti-inflammatory activity of (+)-usnic acid. Filoterapia 71 (2000) 564-566
14. Brock T.G., McNish R.W., and Pertes-Golden M. Arachidonic acid is preferentially metabolized by cyclooxygenase-2 to prostacyclin and prostaglandin E2. J. Biol. Chem. 274 (1999) 11660-11666
15. Isoherranen K., Punnonen K., Jansen C., and Uotilas P. Ultraviolet irradiation induces cyclooxygenase-2 expression in keratinocytes. Brit. J. Dermatol. 140 (1999) 1017-1022
16. Müller-Decker K. Cyclooxygenases in the skin. J. Dtsch. Dermatol. Ges. 8 (2004) 668-675
17. Buckmann S.Y., Gresham A., Hale P., Hruza G., Anast J., Masferrer J., and Pentland A.P. COX-2 expression is induced by UVB exposure in human skin: Implications for the development of skin cancer. Carcinogenesis 19 (1998) 723-729
18. Jocher A., Kessler S., Hornstein S., Schulte Mönting J., and Schempp C.M. The UV-erythema test as a model to investigate the anti-inflammatory potency of topical preparations. Re-evaluation and optimization of the method. Skin Pharmacol. Physiol. 18 (2005) 234-240
19. Laszczyk M., Jager S., Simon-Haarhaus B., Scheffler A., and Schempp C.M. Physical, chemical and pharmacological characterization of a new oleogel-forming triterpene extract from the outer bark of birch (betulae cortex). Planta Med. 72 (2006) 1389-1395
20. Francolini I., Norris P., Piozzi A., Donelli G., and Stoodley P. Usnic acid, a natural antimicrobial agent able to inhibit bacterial biofilm formation on polymer surfaces. Antimicrob. Agents Chemother. 48 (2004) 4360-4365
21. Ashida M., Bito T., Budiayanto A., Ichihashi M., and Ueda M. Involvement of EGF receptor activation in the induction of cyclooxygenase-2 in HaCat keratinocytes after UVB. Exp. Dermatol. 12 (2003) 445-452
22. Bezivin C., Tomasi S., Rouaud I., Delcros J.-G., and Boustie J. Cytotoxic activity of compounds from the lichen Cladonia revoluta. Planta Med. 70 (2004) 874-877
23. Hausen B.M., Emde L., and Marks V. An investigation of the allergenic constituents of Cladonia stellaris (Opiz) Pous & Vezda ("silver moss", "reindeer moss" or "reindeer lichen"). Contact Dermatitis 28 (1993) 70-76
24. Rademaker M. Allergy to lichen acids in a fragrance. Australas. J. Dermatol. 41 (2000) 50-51
25. Rancan F., Rosan S., Boehm K., Fernández E., Hidalgo M.E., Quihot W., Rubio C., Boehm F., Piazena H., and Oltmanns U. Protection against UVB irradiation by natural filters extracted from lichens. J. Photochem. Photobiol. B. 68 (2002) 133-139
26. Odabasoglu F., Aslan A., Cakir A., Suleyman H., Karagoz Y., Halici M., and Bayir Y. Comparison of antioxidant activity and phenolic content of three lichen species. Phytother. Res. 18 (2004) 938-941