Mechanism of internalization of an ICAM-1-derived peptide by human leukemic cell line HL-60: Influence of physicochemical properties on targeted drug delivery

Molecular Pharmaceutics

Volumn 4, Issue 5, 2007, Pages 749-758

  Majumdar, Sumit ^a   Kobayashi, Naoki ^a   Krise, Jeffrey P ^a   Siahaan, Teruna J ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

Doxorubicin; Drug conjugate; Endocytosis; HL 60 cells; HUVEC; ICAM 1 peptide; LFA 1

Indexed keywords

CYCLO(1,12)PENPROLYLARGINYLGLYCYLGLYCYLSERYLVALYLLEUCYLVALYLTHREONYLGLYCYLCYSTEINE; DEOXYGLUCOSE; DOXORUBICIN; FLUORESCEIN ISOTHIOCYANATE; INTERCELLULAR ADHESION MOLECULE 1; NOCODAZOLE; PEPTIDE; SODIUM AZIDE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG TARGETING; ENDOCYTOSIS; HUMAN; HUMAN CELL; HYDROPHOBICITY; INTERNALIZATION; LEUKEMIA CELL LINE; LIPOPHILICITY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; TEMPERATURE DEPENDENCE;

CHEMISTRY, PHYSICAL; DOXORUBICIN; DRUG DELIVERY SYSTEMS; EPITHELIAL CELLS; FLUORESCEIN-5-ISOTHIOCYANATE; HL-60 CELLS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; LEUKEMIA; MOLECULAR STRUCTURE; PEPTIDE FRAGMENTS;

EID: 35548969731     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp0700458     Document Type: Article

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