Patients benefit from the addition of KIR repertoire data to the donor selection procedure for unrelated haematopoietic stem cell transplantation

Molecular Immunology

Volumn 45, Issue 4, 2008, Pages 981-989

  Schellekens, Jennifer ^a   Rozemuller, Erik H ^a   Petersen, Eefke J ^a   van den Tweel, Jan G ^a   Verdonck, Leo F ^a   Tilanus, Marcel G J ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Donor selection; HLA matching; KIR genotype; Unrelated HSCT

Indexed keywords

KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOCYTIC LEUKEMIA; ADULT; ALLOIMMUNITY; ARTICLE; CHRONIC LYMPHATIC LEUKEMIA; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CLINICAL STUDY; CONTROLLED STUDY; DONOR SELECTION; FEMALE; GENOTYPE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HLA SYSTEM; HUMAN; LEUKEMIA CELL; MALE; NATURAL KILLER CELL; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; DONOR SELECTION; FEMALE; HEMATOLOGIC NEOPLASMS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOCOMPATIBILITY TESTING; HLA ANTIGENS; HUMANS; KILLER CELLS, NATURAL; MALE; MIDDLE AGED; RECEPTORS, KIR; RECURRENCE; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS;

EID: 35548968452     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2007.07.040     Document Type: Article

References (33)

1. Biassoni R., Cantoni C., Falco M., Verdiani S., Bottino C., Vitale M., Conte R., Poggi A., Moretta A., and Moretta L. The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions. J. Exp. Med. 183 (1996) 645-650
2. Biron C.A., and Brossay L. NK cells and NKT cells in innate defense against viral infections. Curr. Opin. Immunol. 13 (2001) 458-464
3. Bishara A., De Santis D., Witt C.C., Brautbar C., Christiansen F.T., Or R., Nagler A., and Slavin S. The beneficial role of inhibitory KIR genes of HLA class I NK epitopes in haploidentically mismatched stem cell allografts may be masked by residual donor-alloreactive T cells causing GVHD. Tissue Antigens 63 (2004) 204-211
4. Colonna M., and Samaridis J. Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells. Science 268 (1995) 405-408
5. Colonna M., Borsellino G., Falco M., Ferrara G.B., and Strominger J.L. HLA-C is the inhibitory ligand that determines dominant resistance to lysis by NK1- and NK2-specific natural killer cells. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 12000-12004
6. De Santis D., Bishara A., Witt C.S., Nagler A., Brautbar C., Slavin S., and Christiansen F.T. Natural killer cell HLA-C epitopes and killer cell immunoglobulin-like receptors both influence outcome of mismatched unrelated donor bone marrow transplants. Tissue Antigens 65 (2005) 519-528
7. Dohring C., Scheidegger D., Samaridis J., Cella M., and Colonna M. A human killer inhibitory receptor specific for HLA-A1,2. J. Immunol. 156 (1996) 3098-3101
8. Du Z., Gjertson D.W., Reed E.F., and Rajalingam R. Receptor-ligand analyses define minimal killer cell Ig-like receptor (KIR) in humans. Immunogenetics 59 (2007) 1-15
9. Gomez-Lozano N., and Vilches C. Genotyping of human killer-cell immunoglobulin-like receptor genes by polymerase chain reaction with sequence-specific primers: an update. Tissue Antigens 59 (2002) 184-193
10. Gumperz J.E., Litwin V., Phillips J.H., Lanier L.L., and Parham P. The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor. J. Exp. Med. 181 (1995) 1133-1144
11. Heemskerk M.B., Roelen D.L., Dankers M.K., van Rood J.J., Claas F.H., Doxiadis I.I., and Oudshoorn M. Allogeneic MHC class I molecules with numerous sequence differences do not elicit a CTL response. Hum. Immunol. 66 (2005) 969-976
12. Horowitz M.M., Gale R.P., Sondel P.M., Goldman J.M., Kersey J., Kolb H.J., Rimm A.A., Ringden O., Rozman C., Speck B., et al. Graft-versus-leukemia reactions after bone marrow transplantation. Blood 75 (1990) 555-562
13. Hsu K.C., Liu X.R., Selvakumar A., Mickelson E., O'Reilly R.J., and Dupont B. Killer Ig-like receptor haplotype analysis by gene content: evidence for genomic diversity with a minimum of six basic framework haplotypes, each with multiple subsets. J. Immunol. 169 (2002) 5118-5129
14. Leung W., Iyengar R., Turner V., Lang P., Bader P., Conn P., Niethammer D., and Handgretinger R. Determinants of antileukemia effects of allogeneic NK cells. J. Immunol. 172 (2004) 644-650
15. Ljunggren H.G., and Karre K. In search of the 'missing self': MHC molecules and NK cell recognition. Immunol. Today 11 (1990) 237-244
16. Macdonald W.A., Purcell A.W., Mifsud N.A., Ely L.K., Williams D.S., Chang L., Gorman J.J., Clements C.S., Kjer-Nielsen L., Koelle D.M., Burrows S.R., Tait B.D., Holdsworth R., Brooks A.G., Lovrecz G.O., Lu L., Rossjohn J., and McCluskey J. A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition. J. Exp. Med. 198 (2003) 679-691
17. Miller S.A., Dykes D.D., and Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 16 (1988) 1215
18. Moretta A., Vitale M., Bottino C., Orengo A.M., Morelli L., Augugliaro R., Barbaresi M., Ciccone E., and Moretta L. P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities. J. Exp. Med. 178 (1993) 597-604
19. Petersdorf E.W. HLA matching in allogeneic stem cell transplantation. Curr. Opin. Hematol. 11 (2004) 386-391
20. Roelen D.L., Stobbe I., Young N.T., van Bree S.P., Doxiadis I.I., Oudshoorn M., Morris P.J., Wood K.J., and Claas F.H. Permissible and immunogenic HLA-A mismatches: cytotoxic T-cell precursor frequencies reflect graft survival data. Hum. Immunol. 62 (2001) 661-667
21. Ruggeri L., Capanni M., Urbani E., Perruccio K., Shlomchik W.D., Tosti A., Posati S., Rogaia D., Frassoni F., Aversa F., Martelli M.F., and Velardi A. Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science 295 (2002) 2097-2100
22. Schellekens J., Rozemuller E.H., Borst H.P., Otten H.G., van den Tweel J.G., and Tilanus M.G. NK-KIR ligand identification: a quick Q-PCR approach for HLA-C epitope typing. Tissue Antigens 69 (2007) 334-337
23. Thomas E.D., and Blume K.G. Historical markers in the development of allogeneic hematopoietic cell transplantation. Biol. Blood Marrow Transplant 5 (1999) 341-346
24. Torkar M., Norgate Z., Colonna M., Trowsdale J., and Wilson M.J. Isotypic variation of novel immunoglobulin-like transcript/killer cell inhibitory receptor loci in the leukocyte receptor complex. Eur. J. Immunol. 28 (1998) 3959-3967
25. Trinchieri G., and Santoli D. Anti-viral activity induced by culturing lymphocytes with tumor-derived or virus-transformed cells. Enhancement of human natural killer cell activity by interferon and antagonistic inhibition of susceptibility of target cells to lysis. J. Exp. Med. 147 (1978) 1314-1333
26. Trompeter H.I., Gomez-Lozano N., Santourlidis S., Eisermann B., Wernet P., Vilches C., and Uhrberg M. Three structurally and functionally divergent kinds of promoters regulate expression of clonally distributed killer cell Ig-like receptors (KIR), of KIR2DL4, and of KIR3DL3. J. Immunol. 174 (2005) 4135-4143
27. Uhrberg M., Valiante N.M., Shum B.P., Shilling H.G., Lienert-Weidenbach K., Corliss B., Tyan D., Lanier L.L., and Parham P. Human diversity in killer cell inhibitory receptor genes. Immunity 7 (1997) 753-763
28. Uhrberg M., Parham P., and Wernet P. Definition of gene content for nine common group B haplotypes of the Caucasoid population: KIR haplotypes contain between seven and eleven KIR genes. Immunogenetics 54 (2002) 221-229
29. van Dijk A., Melchers R., Hilkes Y., Rozemuller E., and Tilanus M. HLA-DRB sequencing-based typing: an improved protocol which shows complete DRB exon 2 sequences and includes exon 3 of HLA-DRB4/5. Tissue Antigens 69 (2007) 61-63
30. van Dijk A., Melchers R., Tilanus M., and Rozemuller E. HLA-DQB1 sequencing-based typing updated. Tissue Antigens 69 (2007) 64-65
31. Wagtmann N., Rajagopalan S., Winter C.C., Peruzzi M., and Long E.O. Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer. Immunity 3 (1995) 801-809
32. Winter C.C., and Long E.O. A single amino acid in the p58 killer cell inhibitory receptor controls the ability of natural killer cells to discriminate between the two groups of HLA-C allotypes. J. Immunol. 158 (1997) 4026-4028
33. Witt C.S., and Christiansen F.T. The relevance of natural killer cell human leucocyte antigen epitopes and killer cell immunoglobulin-like receptors in bone marrow transplantation. Vox Sang. 90 (2006) 10-20