Leukapheresis and cranial irradiation in patients with hyperleukocytic acute myeloid leukemia: No impact on early mortality and intracranial hemorrhage

American Journal of Hematology

Volumn 82, Issue 11, 2007, Pages 976-980

  Chang, Ming Chih ^a   Chen, Tsai Yun ^b   Tang, Jih Luh ^c   Lan, Yii Jenq ^d   Chao, Tsu Yi ^e   Chiu, Chang Fang ^f   Ho, Hsin Tsung ^a  

^a MACKAY MEMORIAL HOSPITAL   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^d CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^e TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^f CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; ARTICLE; BRAIN HEMORRHAGE; CANCER PATIENT; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; INCIDENCE; LEUKAPHERESIS; LEUKOCYTE COUNT; LEUKOSTASIS; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MORTALITY; PRIORITY JOURNAL; RESPIRATORY DISTRESS; RETROSPECTIVE STUDY; RISK FACTOR; SKULL IRRADIATION; SURVIVAL; SYMPTOMATOLOGY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; FEMALE; HUMANS; INTRACRANIAL HEMORRHAGES; KAPLAN-MEIERS ESTIMATE; LEUKAPHERESIS; LEUKEMIA, MYELOID, ACUTE; LEUKOCYTE COUNT; LEUKOSTASIS; MALE; MIDDLE AGED; RESPIRATORY INSUFFICIENCY; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 35548957852     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.20939     Document Type: Article

References (30)

1. Majhail NS, Cichtin AE. Acute leukemia with a very high leukocyte count: Confronting a medical emergency. Cleve Clin J Med 2004;8:633-637.
2. Baer MR. Management of unusual presentations of acute leukemia. Hematol Oncol Clin North Am 1993;7:275-292.
3. Lester T, Johnson JW, Cuttner J. Pulmonary leukostasis as the single worst prognostic factor in patients with acute myelocytic leukemia and hyperleukocytosis. Am J Med 1985;579:43-48.
4. Lokich J, Moloney WC. Fatal pulmonary leukostasis following treatment in acute myelogenous leukemia. Arch Intern Med 1972;130:759-762.
5. Nowacki P, Fryze C, Zdziarska B, et al. Central nervous system leukostasis in patients with leukemias and lymphomas. Folia Neuropathol 1995;33:59-65.
6. Porcu P, Cripe LD, Ng EW, et al. Hyperleukocytic leukemias and leukostasis: A review of pathophysiology, clinical presentation, and management. Leuk lymphoma 2000;39:1-18.
7. Dutcher JP, Schiffer CA, Wiemik PH. Hyperleukocytosis in adult acute non-lymphocytic leukemia: Impact on remission rate and duration, and survival. J Clin Oncol 1987;5:1364-1372.
8. Wald BR, Heisel M, Ortega JA. Frequency of early death in children with acute leukemia presenting with hyperleukostasis. Cancer 1982;50:150-153.
9. Bunin NJ, Pui CH. Differing complications of hyperleukocytosis in children with acute lymphoblastic or acute nonlymphoblastic leukemia. J Clin Oncol 1985;3:1590-1595.
10. Porcu P, Farag S, Marcucci G, et al. Leukocytoreduction for acute leukemia. Ther Apher 2002;6:15-23.
11. von Buchem MA, te Velde J, Willemze R, et al. Leukostasis, an underestimated cause of death in leukemia. Blut 1988;56:39-44.
12. Soares FA, Landen Magnani GA, de Miranda Cardoso MC. Pulmonary leukostasis without hyperleukocytosis. Am J Hematol 1992;40:28-32.
13. Porcu P, Danielson CF, Orazi A, et al. Therapeutic leukapheresis in hyperleukocytic leukemias: Lack of correlation between degree of cytoreduction and early mortality rate. Br J Haematol 1997;98:433-436.
14. Stucki A, Rivier AS, Gikic M, et al. Endothelial cell activation by myeloblasts : Molecular mechanisms of leukostasis and leukemic cell dissemination. Blood 2001;97:2121-2129.
15. Novothy JR, Nuckel H, Duhrsen U. Correlation expression of CD56/NCAM and severe leukostasis in hyperleukocytic acute myelomonocytic leukemia. Eur J Haematol 2006;76:299-308.
16. Cavenagh JD, Gordon-Smith EC, Gibson FM, et al. Acute myeloid leukemia blast cells bind to human endothelium in vitro utilizing E-selectin and vascular cell adhesion molecule-1 (VCAM-1). Br J Haematol 1993;85:285-291.
17. Bennett JM, Catovsky D, Daniel MT, et al. Proposed revised criteria for the classification of acute myeloid leukemia. Ann Intern Med 1985;103:460-462.
18. Myers TJ, Cole SR, Klatsky AU, et al. Respiratory failure due to pulmonary leukostasis following chemotherapy of acute nonlymphocytic leukemia. Cancer 1983;51:1808-1813.
19. Tryka AF, Godleski JJ, Fanta CH. Leukemic cell lysis pneumonopathy: A complication of treated myeloblasts leukemia. Cancer 1982;50:2763-2770.
20. Wurthner JU, Kohler G, Behringer D, et al. Leukostasis followed by hemorrhage complicating the initiation of chemotherapy in patients with acute myeloid leukemia and hyperleukocytosis: A clinicopathologic report of four cases. Cancer 1999;85:368-374.
21. Nelson SC, Brugger Cs, Kurtzberg J, et al. Management of leukemic hyperleukocytosis with hydration, urinary alkalization, and allopurinol: Are cranial irradiation and invasive cytoreduction necessary? Am J Pediatr Hematol Oncol 1993;15:351-355.
22. Giles FJ, Shen Y, Kantarjian HM, et al. Leukapheresis reduces early mortality in patients with acute myeloid leukemia with high white cell counts but does not improve long-term survival. Leuk Lymphoma 2001;42:67-73.
23. Thiébaut A, Thomas X, Belhabri A, et al. Impact of pre-induction therapy leukapheresis on treatment outcome in adult acute myelogenous leukemia presenting with hyperleukocytosis. Ann Hematol 2000;79:501-506.
24. Lowe EJ, Pui CH, Hancock MI, et al. Early complications in children with acute lymphoblastic leukemia presenting with hyperleukocytosis. Pediatr Blood Cancer 2005;5:10-15.
25. Flasshave M, Schuette J, Sauerwein W, et al. Pulmonary and cerebral irradiation for hyperleukocytosis in acute myelomonocytic leukemia. Leukemia 1999;8:1972 (letter).
26. Gilchrist GS, Fountain KS, Dearth JC, et al. Cranial irradiation in the management of extreme leukemic leukocytosis complicating childhood acute lymphocytic leukemia. J Pediatr 1981;98:257-259.
27. Butler RW, Hill JM, Steinherz PG. et al. Neuropsychologic effects of cranial irradiation, intrathecal methotrexate, and systemic methotrexate in childhood cancer. J Clin Oncol 1994;12:2621-2629.
28. Wiernik PH, Serpick AA. Factors effecting remission and survival in adult acute nonlymphocytic leukemia. Medicine 1970;49:505-513.
29. Vidal C, Baer MR, Bloomfield CD. Uncommon pattern of presentation of leukemia. Hematol Oncol 1999;17:11-29.
30. van Buchem MA, Hogendoorn PC, Bruijn JA, et al. Endothelial activation antigens in pulmonary leukocytosis in leukemia. Acta Haematol 1993;90:29-33.