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1-(β-D-Dioxolane) Thymine Is Effective against HIV-1-containing TAM and M184V
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Lennerstrand J, Bluemling G, Ruckstuhl M, Bennett M, Chu C, Schinazi R. 1-(β-D-Dioxolane) Thymine Is Effective against HIV-1-containing TAM and M184V. 13th Conf Retrovir Opportun Infect abstract 46. 2007.
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Hernandez-Santiago BI, Chen H, Asif G, Beltran T, Mao S, Hurwitz SJ, Grier J, McClure HM, Chu CK, Liotta DC, Schinazi RF. Pharmacology and pharmacokinetics of the antiviral agent beta-D-2′,3′-dideoxy-3′-oxa-5-fluorocytidine in cells and rhesus monkeys. Antimicrob Agents Chemother 2005 Jul;49(7):2589-97.
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39
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33847027993
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Highly selective action of triphosphate metabolite of 4′-ethynyl D4T: A novel anti-HIV compound against HIV-1 RT
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Yang G, Dutschman GE, Wang CJ, Tanaka H, Baba M, Anderson KS, Cheng YC. Highly selective action of triphosphate metabolite of 4′-ethynyl D4T: a novel anti-HIV compound against HIV-1 RT. Antiviral Res 2007 Mar;73(3):185-91.
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Tanaka H, Haraguchi K, Kumamoto H, Baba M, Cheng YC. 4′-Ethynylstavudine (4′-Ed4T) has potent anti-HIV-1 activity with reduced toxicity and shows a unique activity profile against drug-resistant mutants. Antivir Chem Chemother 2005;16(4):217-21.
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Nitanda T, Wang X, Kurnamoto H, Haraguchi K, Tanaka H, Cheng YC, Baba M. Anti-human immunodeficiency virus type 1 activity and resistance profile of 2′,3′-didehydro-3′-deoxy-4′-ethynylthymidine in vitro. Antimicrob Agents Chemother 2005 Aug;49(8):3355-60.
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Intracellular Metabolism of 2-Deoxy-4′-C-Ethynyl-2-Fluoroadenosine, a Novel 4′-C-Ethynyl Nucleoside Analog Potent against Multidrug-resistant HIV-1 Variants
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Nakata H, Koh Y, Kodama E, Yang G, Kohgo S, Hayakawa H, et al. Intracellular Metabolism of 2-Deoxy-4′-C-Ethynyl-2-Fluoroadenosine, a Novel 4′-C-Ethynyl Nucleoside Analog Potent against Multidrug-resistant HIV-1 Variants. 13th Conf Retrovir Opportun Infect abstract 499. 2006.
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43049114748
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DUET-2: 24 week results of a phase III randomised double-blind trial to evaluate the efficacy and safety of TMC125 versus placebo in 591 treatment-experienced HIV-1 infected patients
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Eiznhamet DA, Creagh T, Ruckle JL, Tolbert DT, Giltnet J, Dutta B, Flavin MT, Jenta T, Xu ZQ. Safety and pharmacokinetic profile of multiple escalating doses of (+)-calanolide A, a naturally occurring nonnucleoside reverse transcriptase inhibitor, in healthy HIV-negative volunteers. HIV Clin Trials 2002 Nov;3(6):435-50.
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50
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0035037065
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Buckheit RW, Jr., Watson K, Fliakas-Boltz V, Russell J, Loftus TL, Osterling MC, Turpin JA, Pallansch LA, White FL, Lee JW, Lee SH, Oh JW, Kwon HS, Chung SG, Cho EH. SJ-3366, a unique and highly potent nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 (HIV-1) that also inhibits HIV-2. Antimicrob Agents Chemother 2001 Feb;45(2):393-400.
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