Psychopharmacologic strategies and associated challenges in the long-term treatment of schizophrenia

Journal of the American Psychiatric Nurses Association

Volumn 13, Issue SUPPL. 5, 2007, Pages

  McEnany, Geoffry Phillips ^a  

^a UNIVERSITY OF MASSACHUSETTS LOWELL   (United States)

Author keywords

Adherence; Antipsychotic drugs; Long term treatment; Prevention; Relapse; Schizophrenia

Indexed keywords

EID: 35548951801     PISSN: 10783903     EISSN: 15325725     Source Type: Journal    
DOI: 10.1177/1078390307304078     Document Type: Article

References (32)

1. American Psychiatric Association. (2004). Practice guideline for the treatment of patients with schizophrenia (2nd ed.). Arlington, VA: Author.
2. Andreasen, N.C. (1985). The broken brain. New York: Harper Collins.
3. Bezchlibnyk-Butler, K., & Jeffries, J. (2005). Clinical handbook of psychotropic drugs. Seattle, WA: Hogrefe & Huber.
4. Brook, S., Lucey, J.V., & Gunn, K.P. (2000). Intramuscular ziprasidone compared with intramuscular haloperidol in the treatment of acute psychosis. Ziprasidone I.M. study group. Journal of Clinical Psychiatry, 61, 933-941.
5. Burris, K.D., Molski, T.F., Xu, C., Ryan, E., Tottori, K., Kikuchi, T., et al. (2002). Aripiprazole, a novel antipsychotic, is a high-affinity partial agonist at human dopamine D2 receptors. Journal of Pharmacology and Experimental Therapeutics, 302, 381-389.
6. Csernansky, J.G., Mahmoud, R., & Brenner, R. (2002). A comparison of risperidone and haloperidol for the prevention of relapse in patients with schizophrenia. New England Journal of Medicine, 346, 16-22.
7. Currier, G.W. (2000). Atypical antipsychotic medications in the psychiatric emergency service. Journal of Clinical Psychiatry, 61 (Suppl. 14), 21-26.
8. Daniel, D., Stock, E., Wilber, R., Marcus, R., Carson, W., Manos, G., et al. (2004). Intramuscular aripiprazole in acutely agitated psychotic patients. Presented at APA, New York, 2004.
9. Ghaemi SN, Hsu DJ, Rosenquist KJ et al (2006). Extrapyramidal side effects with atypical neuroleptics in bipolar disorder. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 30(2), 209-13.
10. Glick, I.D., & Berg, P.H. (2002). Time to study discontinuation, relapse, and compliance with atypical or conventional antipsychotics in schizophrenia and related disorders. International Clinical Psychopharmacology, 17, 65-68.
11. Horacek, J., Bubenikova-Valesova, V., Kopecek, M., Palenicek, T., Dockery, C., Mohr, P., et al. (2006). Mechanism of action of atypical antipsychotic drugs and the neurobiology of schizophrenia. CNS Drugs, 20, 389-409.
12. Hudson, T.J., Owen, R.R., Thrush, C.R., Han, X., Pyne, J.M., Thapa, P., et al. (2004). A pilot study of barriers to medication adherence in schizophrenia. Journal of Clinical Psychiatry, 65, 211-216.
13. Jarboe, K. (2007). Considering the impact of overall patient health when choosing antipsychotic therapy. Journal of the American Psychiatric Nurses Association, 13 (Suppl. 1), 23S-28S.
14. Kane, J.M. (2006). Review of treatments that can ameliorate nonadherence in patients with schizophrenia. Journal of Clinical Psychiatry, 67, 9-14.
15. Kapur, S., & Remington, G. (2001). Atypical antipsychotics: New directions and new challenges in the treatment of schizophrenia. Annual Review of Medicine, 52, 503-517.
16. Kasper, S., Lerman, M.N., McQuade, R.D., Saha, A., Carson, W.H., Ali, M., et al. (2003). Efficacy and safety of aripiprazole vs. haloperidol for long-term maintenance treatment following acute relapse of schizophrenia. International Journal of Neuropsychopharmacology, 6, 325-337.
17. Kay, S.R., Fiszbein, A., & Opler, L.A. (1987). The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophrenia Bulletin, 13, 261-276.
18. Lasser, R.A., Bossie, C.A., Gharabawi, G.M., & Kane, J.M. (2005). Remission in schizophrenia: Results from a 1-year study of long-acting risperidone injection. Schizophrenia Research, 77, 215-227.
19. Leucht, S., Barnes, T.R., Kissling, W., Engel, R.R., Correll, C., & Kane, J.M. (2003). Relapse prevention in schizophrenia with new-generation antipsychotics: A systematic review and exploratory meta-analysis of randomized, controlled trials. American Journal of Psychiatry, 160, 1209-1222.
20. Leucht, S., & Heres, S. (2006). Epidemiology, clinical consequences, and psychosocial treatment of nonadherence in schizophrenia. Journal of Clinical Psychiatry, 67, 3-8.
21. Lieberman, J.A., Stroup, T.S., McEvoy, J.P., Swartz, M.S., Rosenheck, R.A., Perkins, D.O., et al. (2005). Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. New England Journal of Medicine, 353, 1209-1223.
22. Marder, S.R. (2003). Overview of partial compliance. Journal of Clinical Psychiatry, 64 (Suppl. 16), 3-9.
23. Osterberg, L., & Blaschke, T. (2005). Adherence to medication. New England Journal of Medicine, 353, 487-497.
24. Perkins, D.O. (2002). Predictors of noncompliance in patients with schizophrenia. Journal of Clinical Psychiatry, 63, 1121-1128.
25. Pigott, T.A., Carson, W.H., Saha, A.R., Torbeyns, A.F., Stock, E.G., & Ingenito, G.G. (2003). Aripiprazole for the prevention of relapse in stabilized patients with chronic schizophrenia: A placebo-controlled 26-week study. Journal of Clinical Psychiatry, 64, 1048-1056.
26. Ray, W.A. (2005). Observational studies of drugs and mortality. New England Journal of Medicine, 353, 2319-2321.
27. Rettenbacher, M.A., Hofer, A., Eder, U., Hummer, M., Kemmler, G., Weiss, E.M., et al. (2004). Compliance in schizophrenia: Psychopathology, side effects, and patients' attitudes toward the illness and medication. Journal of Clinical Psychiatry, 65, 1211-1218.
28. Roth, B.L., Sheffler, D.J., & Potkin, S.G. (2003). Atypical antipsychotic drug actions: Unitary or multiple mechanisms for "atypicality" ? Clinical Neuroscience Research, 3, 108-117.
29. Stahl, S.M. (2003). Essential psychopharmacology. Cambridge, UK: Cambridge University Press.
30. Stuart, G., & Laraia, M. (2006). Principles & practice of psychiatric nursing (8th ed.). St. Louis, MO: Elsevier Mosby.
31. Weiden, P.J., Kozma, C., Grogg, A., & Locklear, J. (2004). Partial compliance and risk of rehospitalization among California Medicaid patients with schizophrenia. Psychiatric Services, 55, 886-891.
32. Wright, P., Birkett, M., David, S.R., Meehan, K., Ferchland, I., Alaka, K.J., et al. (2001). Double-blind, placebo-controlled comparison of intramuscular olanzapine and intramuscular haloperidol in the treatment of acute agitation in schizophrenia. American Journal of Psychiatry, 158, 1149-1151.