Neuroprotective effects of emodin-8-O-β-d-glucoside in vivo and in vitro

European Journal of Pharmacology

Volumn 577, Issue 1-3, 2007, Pages 58-63

  Wang, Chaoyun ^a   Zhang, Dalei ^b   Ma, Hongmei ^c   Liu, Juntian ^a  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^b INSTITUTE OF PROCESS ENGINEERING   (China)

^c CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

Emodin 8 O d glucoside; Ischemia and reperfusion; Lipid peroxidation; Neuroprotection; Polygonum cuspidatum Sieb. et Zucc

Indexed keywords

EMODIN 8 O BETA DEXTRO GLUCOSIDE; GLUCOSIDE; GLUTAMIC ACID; HERBACEOUS AGENT; MALONALDEHYDE; PLANT EXTRACT; POLYGONUM CUSPIDATUM EXTRACT; SUPEROXIDE DISMUTASE; TRIPHENYLTETRAZOLIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION; BRAIN INJURY; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG MECHANISM; DRUG TISSUE LEVEL; FETUS; IN VITRO STUDY; IN VIVO STUDY; ISCHEMIA; MALE; NEUROPROTECTION; NONHUMAN; POLYGONUM CUSPIDATUM; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

ANIMALS; ANTHRAQUINONES; ANTIOXIDANTS; BEHAVIOR, ANIMAL; BRAIN; BRAIN CHEMISTRY; BRAIN ISCHEMIA; CELLS, CULTURED; CEREBRAL CORTEX; CEREBRAL INFARCTION; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSIDES; GLUTAMIC ACID; MALE; MALONDIALDEHYDE; NEURONS; NEUROPROTECTIVE AGENTS; POLYGONUM CUSPIDATUM; RATS; RATS, WISTAR; REPERFUSION INJURY; SUPEROXIDE DISMUTASE;

EID: 35448973373     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.08.033     Document Type: Article

References (20)

1. Bettler B., and Mulle C. Review: neurotransmitter receptors. II. AMPA and kainate receptors. Neuropharmacology 34 (1995) 123-139
2. Buege J.A., and Aust S.D. Microsomal lipid peroxidation. Methods Enzymol. 52 (1978) 302-310
3. Chen L., Yang F.Q., Zhang T.Y., Han Y.S., and Chen S.W. Separation and analysis of resveratrol and piceid in Polygonum cuspidatum Sieb. et Zicc. J. Instrum. Anal. 19 (2000) 60
4. Chu X., Sun A., and Liu R. Preparative isolation and purification of five compounds from the Chinese medicinal herb Polygonum cuspidatum Sieb. et Zucc by high-speed counter-current chromatography. J. Chromatogr., A 1097 (2005) 33-39
5. Gunasekar P.G., Kanthasamy A.G., Borowitz J.L., and Isom G.E. NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: implication for cell death. J. Neurochem. 65 (1995) 2016-2021
6. Kimura M., Sawada K., Miyagawa T., Kuwada M., Katayama K., and Nishizawa Y. Role of glutamate receptors and voltage-dependent calcium and sodium channels in the extracellular glutamate/aspartate accumulation and subsequent neuronal injury induced by oxygen/glucose deprivation in cultured hippocampal neurons. J. Pharmacol. Exp. Ther. 285 (1998) 178-185
7. Levent G., Ali A., Ahmet A., Polat E.C., Aytac C., Ayse E., and Ahmet S. Oxidative stress and antioxidant defense in patients with chronic hepatitis C patients before and after pegylated interferon alfa-2b plus ribavirin therapy. J. Transl. Med. 4 (2006) 25
8. Longa E.Z., Weinstein P.R., Carlson S., and Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20 (1989) 84-91
9. Love S. Oxidative stress in brain ischemia. Brain Pathol. 9 (1999) 119-131
10. Mason R.B., Pluta R.M., Walbridge S., Wink D.A., Oldfield E.H., and Boock R.J. Production of reactive oxygen species after reperfusion in vitro and in vivo. J. Neurosurg. 93 (2000) 99-107
11. Medina J., and Moreno-Otero R. Pathophysiological basis for antioxidant therapy in chronic liver disease. Drugs 65 (2005) 2445-2461
12. Mhairi Macrae I. New models of focal cerebral ischemia. Br. J. Clin. Pharmacol. 34 (1992) 302-308
13. Papadopoulos M.C., Koumenis I.L., Xu L., and Giffard R.G. Potentiation of murine astrocyte antioxidant defence by bcl-2: protection in part reflects elevated glutathione levels. Eur. J. Neurosci. 10 (1998) 1252-1260
14. Pennypacker K.R., Hernandez H., Benkovic S., Morgan D.G., Willing A.E., and Sanberg P.R. Induction of presenilins in the rat brain after middle cerebral arterial occlusion. Brain Res. Bull. 48 (1999) 539-543
15. Purohit V., and Brenner D.A. Mechanisms of alcohol-induced hepatic fibrosis: a summary of the Ron Thurman Symposium. Hepatology 43 (2006) 872-878
16. Schwabe R.F., and Brenner D.A. Mechanisms of liver injury. I. TNF-alpha-induced liver injury: role of IKK, JNK, and ROS pathways. Am. J. Physiol. Gastrointest. Liver Physiol. 290 (2006) G583-G589
17. Truelove D., Shuaib A., Ljaz S., Richardson S., and Kalra J. Superoxide dismutase, catalase, and U78517F attenuate neuronal damage in gerbils with repeated brief ischemic insults. Neurochem. Res. 19 (1994) 665-671
18. White B.C., Sullivan J.M., DeGracia D.J., O'Neil B.J., Neumar R.W., Grossman L.I., Rafols J.A., and Krause G.S. Brain ischemia and reperfusion: molecular mechanisms of neuronal injury. J. Neurol. Sci. 179 (2000) 1-33
19. Yang F., Zhang T., and Ito Y. Large-scale separation of resveratrol, anthraglycoside A and anthraglycoside B from Polygonum cuspidatum Sieb. et Zucc by high-speed counter-current chromatography. J. Chromatogr., A 919 (2001) 443-448
20. Zhu H., Wang Z., Ma C., Tian J., Fu F., Li C., Guo D., Roeder E., and Liu K. Neuroprotective effects of hydroxysafflor yellow A: in vivo and in vitro studies. Planta Med. 69 (2003) 429-433