QT dispersion: Comparison between diabetic and non-diabetic individuals and correlation with cardiac autonomic neuropathy

Hellenic Journal of Cardiology

Volumn 47, Issue 5, 2006, Pages 255-262

  Psallas, Michael ^a,c   Tentolouris, Nikolaos ^a   Cokkinos, Alexandros ^a   Papadogiannis, Dimitrios ^a   Cokkinos, Dennis V ^b   Katsilambros, Nikolaos ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b ONASSIS CARDIAC SURGERY CENTER   (Greece)

^c LAIKO GENERAL HOSPITAL   (Greece)

Author keywords

Diabetes mellitus; QT dispersion; QT interval; QTd

Indexed keywords

ADULT; ARTICLE; CARDIAC AUTONOMIC NEUROPATHY; CARDIOVASCULAR DISEASE; COMPUTER PROGRAM; CONTROLLED STUDY; DEMOGRAPHY; DIABETES MELLITUS; ELECTROCARDIOGRAM; FEMALE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; QT DISPERSION; CARDIOMYOPATHY; ELECTROCARDIOGRAPHY; HEART MUSCLE CONDUCTION SYSTEM; MIDDLE AGED; PATHOPHYSIOLOGY; RISK FACTOR;

ADULT; CARDIOMYOPATHIES; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; ELECTROCARDIOGRAPHY; FEMALE; HEART CONDUCTION SYSTEM; HUMANS; MALE; MIDDLE AGED; RISK FACTORS;

EID: 35448968259     PISSN: 10117970     EISSN: 10117970     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Bednar MM, Harrigan EP, Anziano RJ, et al: The QT interval. Prog Cardiovasc Dis 2001; 43 (Suppl. 1): 1-45.
2. Lubinski A, Lewicka-Nowak E, Kempa M, et al: New insights into repolarization abnormalities in patients with congenital long QT syndrome. The increased transmural dispersion of repolarization. Pacing Clin Electrophysiol 1998; 21: 172-175.
3. Wolk R, Stec S, Kulakowski P: Extrasystolic beats affect transmural electrical dispersion during programmed electrical stimulation. Eur J Clin Invest 2001; 4: 293-301.
4. Kautzner J, Yi G, Camm AJ, et al: Short- and long-term reproducibility of QT, QTc and QT dispersion measurement in healthy subjects. Pacing Clin Electrophysiol 1994; 17: 928-937.
5. Day CP, McComb JM, Campbell RW: QT dispersion: an indication of arrhythmia risk in patients with long QT intervals. Br Heart J 1990; 63: 342-344.
6. Han J, Moe GK: Non-uniform recovery of excitability in ventricular muscle. Circ Res 1996; 14: 44-45.
7. Kuo CS, Munakata K, Reddy CP, Surawicz B: Characteristics and possible mechanism of ventricular arrhythmia dependent on the dispersion of action potential durations. Circulation 1983; 67: 1356-1367.
8. Naas AAO, Davidson NC, Thompson C, et al: QT and QTc dispersion are accurate predictors of cardiac death in newly diagnosed non-insulin dependent diabetes: cohort study. BMJ 1998; 316: 745-1745.
9. Sawicki PT, Kiwitt S, Bender R, et al: The value of QT interval dispersion for identification of total mortality risk in non-insulin-dependent diabetes mellitus. J Intern Med 1998; 243: 49-56.
10. Christensen PK, Gall MA, Major-Pedersen A: QTc interval length and QT dispersion as predictors of mortality in patients with non-insulin dependent diabetes. J Clin Lab Invest 2000; 60: 323-332.
11. Ewing DJ, Martyn CN, Young RJ, et al: The value of cardiovascular autonomic function tests: 10 year experience in diabetes. Diabetes Care 1985; 8: 491-498.
12. Consensus Statement. American Diabetes Association. Report and Recommendations of the San Antonio Conference on Diabetic Neuropathy. Diabetes 1988; 37: 1000-1004.
13. Ewing DJ, Campbell IW, Clarke BF: The natural history of diabetic autonomic neuropathy. QJM 1980; 49: 95-108.
14. Gerritsen J, Dekker JM, TenVoorde BJ, et al: Impaired autonomic function is associated with increased mortality, especially in subjects with diabetes, hypertension, or a history of cardiovascular disease: the Hoorn Study. Diabetes Care 2001; 24: 1793-1798.
15. Ewing DJ, Boland O, Nielsen JMM Cho CG, et al: Autonomic neuropathy. QT interval lengthening, and unexpected deaths in male diabetic patients. Diabetologia 1991; 34: 182-185.
16. Bellavere F, Ferri M, Guarini L, et al: Prolonged QT period in diabetic autonomic neuropathy; a possible role in sudden cardiac death. Br Heart J 1987; 59: 379-383.
17. Tentolouris N, Katsilambros N, Papazachos G, et al: Corrected QT interval in relation to the severity of the diabetic autonomic neuropathy. Eur J Clin Invest 1997; 27: 1049-1054.
18. Veglio M, Giunti S, Stevens LK, Fuller JH, Cavallo Perrin P: Prevalence of Q-T interval dispersion in type 1 diabetes and its relation with cardiac ischemia: the EURODIAB IDDM Complications Study Group. Diabetes Care 2002; 25: 702-707.
19. Rana BS, Band MM, Ogston S, et al: Relation of QT interval dispersion to the number of different cardiac abnormalities in diabetes mellitus. Am J Cardiol 2002; 90: 483-487.
20. Shimakaburo M, Chibana T, Yoshida H, et al: Increased QT dispersion and cardiac adrenergic dysinnervation in diabetic patients with autonomic neuropathy. Am J Cardiol 1996; 78: 1057-1059.
21. Takebayashi K, Sugita R, Tayama K, et al: The connection between QT dispersion and autonomic neuropathy in patients with type 2 diabetes. Exp Clin Endocrinol Diabetes 2003; 111: 351-357.
22. The expert committee on the diagnosis, classification of diabetes mellitus: report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 1997; 20: 1183-1197.
23. Howorka K, Pumprla J, Haber P, et al: Effects of physical training on heart rate variability in diabetic patients with various degrees of cardiovascular autonomic neuropathy. Cardiovasc Res 1997; 34: 206-214.
24. Cardone C, Painsco P, Marchetti G, et al: Cough test to assess cardiovascular autonomic neuropathy reflexes in diabetes. Diabetes Care 1990; 13: 719-720.
25. Bazett HC: An analysis of the time relations of the electrocardiogram. Heart 1920; 7: 353-357.
26. Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure: The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (JNC VII). JAMA 2003; 289: 2580-12572.
27. Friedewald WT, Levy RI, Fredrickson DS: Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972; 18: 499-502.
28. Elming H, Holm E, Jun L, et al: The prognostic value of QT interval and QT interval dispersion in all-cause and cardiac mortality in a population of Danish citizens. Eur Heart J 1998; 19: 1391-1400.
29. Arildsen H, May O, Christiansen EH, et al: Increased QT dispersion in patients with insulin depended diabetes mellitus. Int J Cardiol 1999; 71: 235-242.
30. Aytemir K, Aksoyek S, Ozer N, et al: QT dispersion and autonomic nervous system function in patients with type 1 diabetes. Int J Cardiol 1998; 65: 45-50.
31. Wei K, Dorian P, Newman D, Langer A: Association between QT dispersion and autonomic dysfunction in patients with diabetes mellitus. J Am Coll Cardiol 1995; 26: 859-863.
32. Sahu P, Lim PO, Rana BS, et al: QT dispersion in medicine: electrophysiological Holy Grail or fool's gold? QJM 2000; 93: 425-431.