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Volumn 4, Issue C, 2001, Pages 41-72

DNA base modifications in aging

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EID: 35448967875     PISSN: 15663124     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1566-3124(01)04027-5     Document Type: Article
Times cited : (2)

References (180)
  • 2
    • 0023988217 scopus 로고
    • Oxidative damage to DNA: relation to species metabolic rate and life span
    • Adelman R., Saul R.L., and Ames B.N. Oxidative damage to DNA: relation to species metabolic rate and life span. Proc. Natl. Acad. Sci. USA 85 (1988) 2706-2708
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 2706-2708
    • Adelman, R.1    Saul, R.L.2    Ames, B.N.3
  • 3
    • 0014040945 scopus 로고
    • The role of DNA lesions in processes leading to aging in mice
    • Alexander P. The role of DNA lesions in processes leading to aging in mice. Symp. Soc. Exp. Biol. 21 (1967) 29-50
    • (1967) Symp. Soc. Exp. Biol. , vol.21 , pp. 29-50
    • Alexander, P.1
  • 4
    • 0024460992 scopus 로고
    • Endogenous oxidative damage, aging, and cancer
    • Ames B.N. Endogenous oxidative damage, aging, and cancer. Free Rad. Res. Commun. 7 (1989) 121-128
    • (1989) Free Rad. Res. Commun. , vol.7 , pp. 121-128
    • Ames, B.N.1
  • 5
    • 0025902273 scopus 로고
    • Endogenous mutagens and the causes of aging and cancer
    • Ames B.N., and Gold L.S. Endogenous mutagens and the causes of aging and cancer. Mutat. Res. 250 (1991) 3-16
    • (1991) Mutat. Res. , vol.250 , pp. 3-16
    • Ames, B.N.1    Gold, L.S.2
  • 8
    • 0011223915 scopus 로고
    • Hazards of nitrate, nitrite, and N-nitroso compounds in human nutrition
    • Hathcock J.N. (Ed), Academic Press, New York
    • Aucher M.C. Hazards of nitrate, nitrite, and N-nitroso compounds in human nutrition. In: Hathcock J.N. (Ed). Nutritional Toxicology (1982), Academic Press, New York 328-367
    • (1982) Nutritional Toxicology , pp. 328-367
    • Aucher, M.C.1
  • 9
    • 0019413555 scopus 로고
    • Aberrant methylation of liver DNA in rats during hepatotoxicity
    • Barrows L.R., and Shank R.C. Aberrant methylation of liver DNA in rats during hepatotoxicity. Toxicol. Appl. Pharmacol. 60 (1981) 334-345
    • (1981) Toxicol. Appl. Pharmacol. , vol.60 , pp. 334-345
    • Barrows, L.R.1    Shank, R.C.2
  • 10
    • 0020324376 scopus 로고
    • Nonenzymatic methylation of DNA by S-adenosyl methionine in vitro
    • Barrows L.R., and Magee P.N. Nonenzymatic methylation of DNA by S-adenosyl methionine in vitro. Carcinogenesis 3 (1982) 349-351
    • (1982) Carcinogenesis , vol.3 , pp. 349-351
    • Barrows, L.R.1    Magee, P.N.2
  • 11
    • 2642622799 scopus 로고
    • Genetic effects of thymine glycol: site-specific mutagenesis and molecular modeling studies
    • Basu A.K., Loechler L.E., Leadon S.A., and Essigmann J.M. Genetic effects of thymine glycol: site-specific mutagenesis and molecular modeling studies. Proc. Natl. Acad. Sci. USA 86 (1989) 7677-7681
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 7677-7681
    • Basu, A.K.1    Loechler, L.E.2    Leadon, S.A.3    Essigmann, J.M.4
  • 13
    • 0030839865 scopus 로고    scopus 로고
    • Oxidative decay of DNA
    • Beckman K.B., and Ames B.N. Oxidative decay of DNA. J. Biol. Chem. 272 (1997) 19633-19636
    • (1997) J. Biol. Chem. , vol.272 , pp. 19633-19636
    • Beckman, K.B.1    Ames, B.N.2
  • 14
    • 0031916984 scopus 로고    scopus 로고
    • The free radical theory of aging matures
    • Bechman K.B., and Ames B.N. The free radical theory of aging matures. Physiol. Rev. 78 (1998) 547-581
    • (1998) Physiol. Rev. , vol.78 , pp. 547-581
    • Bechman, K.B.1    Ames, B.N.2
  • 15
    • 0001803613 scopus 로고
    • DNA Damage and Aging
    • Yu B.P. (Ed), CRC Press, Boca Raton, FL
    • Bernstien H., and Gensler H. DNA Damage and Aging. In: Yu B.P. (Ed). Free Radicals in Aging (1993), CRC Press, Boca Raton, FL 89-122
    • (1993) Free Radicals in Aging , pp. 89-122
    • Bernstien, H.1    Gensler, H.2
  • 16
    • 0022540321 scopus 로고
    • CpG-rich islands and the function of DNA methylation
    • Bird A.P. CpG-rich islands and the function of DNA methylation. Nature 321 (1986) 209-211
    • (1986) Nature , vol.321 , pp. 209-211
    • Bird, A.P.1
  • 17
    • 0026653420 scopus 로고
    • The essentials of DNA methylation
    • Bird A. The essentials of DNA methylation. Cell 70 (1992) 5-8
    • (1992) Cell , vol.70 , pp. 5-8
    • Bird, A.1
  • 19
    • 0029165277 scopus 로고
    • DNA damage, mutation and fine structure DNA repair in aging
    • Bohr V.A., and Anson R.M. DNA damage, mutation and fine structure DNA repair in aging. Mutat. Res. 338 (1995) 25-34
    • (1995) Mutat. Res. , vol.338 , pp. 25-34
    • Bohr, V.A.1    Anson, R.M.2
  • 21
    • 0000571086 scopus 로고
    • Modification of DNA by reducing sugars: A possible mechanism of nucleic acid aging and age-related dysfunction in gene expression
    • Bucala R., Model P., and Cerami A. Modification of DNA by reducing sugars: A possible mechanism of nucleic acid aging and age-related dysfunction in gene expression. Proc. Natl. Acad. Sci. USA 81 (1984) 105-109
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 105-109
    • Bucala, R.1    Model, P.2    Cerami, A.3
  • 22
    • 0010412559 scopus 로고
    • Modification of DNA by glucose-6-phosphate induces DNA rearrangements in an E. coli plasmid
    • Bucala R., Model P., Russel M., and Cerami A. Modification of DNA by glucose-6-phosphate induces DNA rearrangements in an E. coli plasmid. Proc. Natl. Acad. Sci. USA 82 (1985) 8439-8442
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 8439-8442
    • Bucala, R.1    Model, P.2    Russel, M.3    Cerami, A.4
  • 23
    • 0027466334 scopus 로고
    • Transposition of an Alu-containing element induced by DNA-advanced glycosylation endproducts
    • Bucala R., Lee A.T., Rourke L., and Cerami A. Transposition of an Alu-containing element induced by DNA-advanced glycosylation endproducts. Proc. Natl. Acad. Sci. USA 90 (1993) 2666-2670
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2666-2670
    • Bucala, R.1    Lee, A.T.2    Rourke, L.3    Cerami, A.4
  • 24
    • 0031428488 scopus 로고    scopus 로고
    • Artifacts associated with the measurement of oxidized bases
    • Cadet J., Douki T., and Ravanat J.-L. Artifacts associated with the measurement of oxidized bases. Environ. Health Perspect. 105 (1997) 1034-1039
    • (1997) Environ. Health Perspect. , vol.105 , pp. 1034-1039
    • Cadet, J.1    Douki, T.2    Ravanat, J.-L.3
  • 25
    • 0029982187 scopus 로고    scopus 로고
    • Age-dependent increase of indigenous DNA adducts in rat brain is associated with a lipid peroxidation product
    • Cai Q., Tian L., and Wei H. Age-dependent increase of indigenous DNA adducts in rat brain is associated with a lipid peroxidation product. Exp. Gerontol. 31 (1996) 387-396
    • (1996) Exp. Gerontol. , vol.31 , pp. 387-396
    • Cai, Q.1    Tian, L.2    Wei, H.3
  • 26
    • 0024281345 scopus 로고
    • DNA methylation and gene activity
    • Cedar H. DNA methylation and gene activity. Cell 53 (1988) 3-4
    • (1988) Cell , vol.53 , pp. 3-4
    • Cedar, H.1
  • 28
    • 0026592966 scopus 로고
    • 8-Hydroxyguanine, an abundant form of oxidative DNA damage, caused G → T and A → C substitutions
    • Cheng K.D., Cahill D.S., Kassai H., Nishimura S., and Loeb L.A. 8-Hydroxyguanine, an abundant form of oxidative DNA damage, caused G → T and A → C substitutions. J. Biol. Chem. 267 (1992) 166-172
    • (1992) J. Biol. Chem. , vol.267 , pp. 166-172
    • Cheng, K.D.1    Cahill, D.S.2    Kassai, H.3    Nishimura, S.4    Loeb, L.A.5
  • 30
    • 0026653104 scopus 로고
    • Phenol sensitization of DNA to subsequent oxidaitve damage in 8-hydroxyguanine assays
    • Claycamp H.G. Phenol sensitization of DNA to subsequent oxidaitve damage in 8-hydroxyguanine assays. Carcinogenesis 13 (1992) 1289-1292
    • (1992) Carcinogenesis , vol.13 , pp. 1289-1292
    • Claycamp, H.G.1
  • 31
    • 77956831871 scopus 로고
    • DNA Methylation and Chromosome Organization in Eukaryotes
    • Strauss P., and Wilson S. (Eds), Telford Press, Caldwell, N.J
    • Cooney C.A., and Bradury E.M. DNA Methylation and Chromosome Organization in Eukaryotes. In: Strauss P., and Wilson S. (Eds). The Eukaryotic Nucleus: Molecular Biochemistry and Macromolecular Assemblies Vol. 2 (1990), Telford Press, Caldwell, N.J 813-826
    • (1990) The Eukaryotic Nucleus: Molecular Biochemistry and Macromolecular Assemblies , vol.2 , pp. 813-826
    • Cooney, C.A.1    Bradury, E.M.2
  • 32
    • 0027458127 scopus 로고
    • Are somatic cells inherently deficient in methylation metabolism?
    • A proposed mechanism for DNA methylation loss, senescence and aging
    • Cooney C.A. Are somatic cells inherently deficient in methylation metabolism?. A proposed mechanism for DNA methylation loss, senescence and aging. Growth Dev. Aging 57 (1993) 261-273
    • (1993) Growth Dev. Aging , vol.57 , pp. 261-273
    • Cooney, C.A.1
  • 33
    • 0024342297 scopus 로고
    • Cytosine methylation and the fate of CpG dinucleotides in vertebrate genomes
    • Cooper D.N., and Krawczak M. Cytosine methylation and the fate of CpG dinucleotides in vertebrate genomes. Hum. Genet. 83 (1989) 181-188
    • (1989) Hum. Genet. , vol.83 , pp. 181-188
    • Cooper, D.N.1    Krawczak, M.2
  • 34
    • 0026074885 scopus 로고
    • Hypoxemia is associated with mitochondrial DNA damage and gene induction: implications for cardiac disease
    • Corrai-Debrinski M., Stepien G., Shoffner J.M., Lott M.T., Kanter K., and Wallace D.C. Hypoxemia is associated with mitochondrial DNA damage and gene induction: implications for cardiac disease. J. Am. Med. Assoc. 266 (1991) 1812-1820
    • (1991) J. Am. Med. Assoc. , vol.266 , pp. 1812-1820
    • Corrai-Debrinski, M.1    Stepien, G.2    Shoffner, J.M.3    Lott, M.T.4    Kanter, K.5    Wallace, D.C.6
  • 35
    • 0015176511 scopus 로고
    • Genetic factors in aging
    • Curtis H.J. Genetic factors in aging. Adv. Genet. 16 (1971) 305-324
    • (1971) Adv. Genet. , vol.16 , pp. 305-324
    • Curtis, H.J.1
  • 36
    • 0024201717 scopus 로고
    • Determination of 8-hydroxydeoxyguanosine in human urine: a possible assay for in vivo oxidative DNA damage
    • Cundy K.C., Kohen R., and Ames B.N. Determination of 8-hydroxydeoxyguanosine in human urine: a possible assay for in vivo oxidative DNA damage. Basic Life Sci. 49 (1989) 479-482
    • (1989) Basic Life Sci. , vol.49 , pp. 479-482
    • Cundy, K.C.1    Kohen, R.2    Ames, B.N.3
  • 37
    • 0002092648 scopus 로고
    • Cross-linking Hypothesis of Aging: DNA Adducts in Chromatin as a Primary Aging Process
    • Smith K.C. (Ed), Plenum Press, New York
    • Cutler R.G. Cross-linking Hypothesis of Aging: DNA Adducts in Chromatin as a Primary Aging Process. In: Smith K.C. (Ed). Aging, Carcinogenesis and Radiation Biology: The Role of Nucleic Acid Addition Reactions (1976), Plenum Press, New York 443-492
    • (1976) Aging, Carcinogenesis and Radiation Biology: The Role of Nucleic Acid Addition Reactions , pp. 443-492
    • Cutler, R.G.1
  • 38
    • 0021777459 scopus 로고
    • Antioxidants and longevity of mammalian species
    • Cutler R.G. Antioxidants and longevity of mammalian species. Basic Life Sci. 35 (1985) 15-73
    • (1985) Basic Life Sci. , vol.35 , pp. 15-73
    • Cutler, R.G.1
  • 39
    • 0346733787 scopus 로고
    • Dysdifferentation Hypothesis of Aging: A Review
    • Sohol R.S., Bernbaum L.S., and Cutler R.G. (Eds), Raven Press, New York
    • Cutler R.G. Dysdifferentation Hypothesis of Aging: A Review. In: Sohol R.S., Bernbaum L.S., and Cutler R.G. (Eds). Molecular Biology of Aging: Gene Stability and Gene Expression (1985), Raven Press, New York 307-340
    • (1985) Molecular Biology of Aging: Gene Stability and Gene Expression , pp. 307-340
    • Cutler, R.G.1
  • 40
    • 0025973703 scopus 로고
    • Chemical determination of free radical-induced damage to DNA
    • Dizdaroglu M. Chemical determination of free radical-induced damage to DNA. Free Rad. Biol. Med. 10 (1991) 225-242
    • (1991) Free Rad. Biol. Med. , vol.10 , pp. 225-242
    • Dizdaroglu, M.1
  • 41
    • 0019829568 scopus 로고
    • The causes of cancer
    • Doll R., and Peto R. The causes of cancer. J Natl. Cancer Inst. 66 (1981) 1191-1308
    • (1981) J Natl. Cancer Inst. , vol.66 , pp. 1191-1308
    • Doll, R.1    Peto, R.2
  • 42
    • 0024552485 scopus 로고
    • Human lymphocytes aged in vivo have reduced levels of methylation in transcriptionally active and inactive DNA
    • Drinkwater R.D., Blake T.J., Morley A.A., and Tumer D.R. Human lymphocytes aged in vivo have reduced levels of methylation in transcriptionally active and inactive DNA. Mutat. Res. 219 (1989) 29-37
    • (1989) Mutat. Res. , vol.219 , pp. 29-37
    • Drinkwater, R.D.1    Blake, T.J.2    Morley, A.A.3    Tumer, D.R.4
  • 43
    • 0017666918 scopus 로고
    • Tissue distribution of S-adenosylmethionine in the rat: effects of age, sex, and methionine administration of the metabolism of S-adenosylmethionine, S-adenosylhomocysteine and polyamines
    • Eloranta T.O. Tissue distribution of S-adenosylmethionine in the rat: effects of age, sex, and methionine administration of the metabolism of S-adenosylmethionine, S-adenosylhomocysteine and polyamines. Biochem. J. 166 (1977) 521-529
    • (1977) Biochem. J. , vol.166 , pp. 521-529
    • Eloranta, T.O.1
  • 44
    • 0027396509 scopus 로고
    • Influence of CpG methylation and target spacing on V(D)J recombination in a transgenic substrate
    • Engler P., Weng A., and Storb U. Influence of CpG methylation and target spacing on V(D)J recombination in a transgenic substrate. Mol. Cell. Biol. 13 (1993) 571-577
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 571-577
    • Engler, P.1    Weng, A.2    Storb, U.3
  • 46
    • 0020066839 scopus 로고
    • Is cell aging caused by respiration-dependent injury to the mitochondrial genome?
    • Fleming J.E., Miguel J., Cottrell S.F., Yengoyan L.S., and Economos A.C. Is cell aging caused by respiration-dependent injury to the mitochondrial genome?. Gerontology 28 (1982) 44-53
    • (1982) Gerontology , vol.28 , pp. 44-53
    • Fleming, J.E.1    Miguel, J.2    Cottrell, S.F.3    Yengoyan, L.S.4    Economos, A.C.5
  • 47
    • 0025373259 scopus 로고
    • Oxidative damage to DNA during aging: 8-hydroxy-2′-deoxyguanosine in rat organ DNA and urine
    • Fraga C.G., Shigenaga M.K., Park J.W., Degan P., and Ames B.N. Oxidative damage to DNA during aging: 8-hydroxy-2′-deoxyguanosine in rat organ DNA and urine. Proc. Natl. Acad. Sci. USA 87 (1990) 4533-4537
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 4533-4537
    • Fraga, C.G.1    Shigenaga, M.K.2    Park, J.W.3    Degan, P.4    Ames, B.N.5
  • 48
    • 0024516049 scopus 로고
    • Differences in detection of DNA adducts in the 32P-postlabeling assay after either l-butanol extraction or nuclease P1 treatment
    • Gallagher J.E., Jackson M.A., George M.H., Lewtas J., and Robertson I.G.C. Differences in detection of DNA adducts in the 32P-postlabeling assay after either l-butanol extraction or nuclease P1 treatment. Cancer Lett. 45 (1989) 7-12
    • (1989) Cancer Lett. , vol.45 , pp. 7-12
    • Gallagher, J.E.1    Jackson, M.A.2    George, M.H.3    Lewtas, J.4    Robertson, I.G.C.5
  • 49
    • 0022910556 scopus 로고
    • DNA damage during aging of mouse myocardium
    • Gaubatz J.W. DNA damage during aging of mouse myocardium. J. Mol. Cell. Cardiol. 18 (1986) 1317-1320
    • (1986) J. Mol. Cell. Cardiol. , vol.18 , pp. 1317-1320
    • Gaubatz, J.W.1
  • 50
    • 0024586316 scopus 로고
    • Postlabeling analysis of indigenous aromatic DNA adducts in mouse myocardium during aging
    • Gaubatz J.W. Postlabeling analysis of indigenous aromatic DNA adducts in mouse myocardium during aging. Arch. Gerontol. Geriatr. 8 (1989) 47-54
    • (1989) Arch. Gerontol. Geriatr. , vol.8 , pp. 47-54
    • Gaubatz, J.W.1
  • 51
    • 0027400458 scopus 로고
    • Age-related studies on the removal of 7-methylguanine from DNA of mouse kidney tissue following N-methyl-N-nitorsourea treatment
    • Gaubatz J.W., and Tan B.H. Age-related studies on the removal of 7-methylguanine from DNA of mouse kidney tissue following N-methyl-N-nitorsourea treatment. Mutat. Res. 295 (1993) 81-91
    • (1993) Mutat. Res. , vol.295 , pp. 81-91
    • Gaubatz, J.W.1    Tan, B.H.2
  • 52
    • 85053540700 scopus 로고
    • Genomic Instability During Aging of Postmitotic Mammalian Cells
    • Macieira-Coelhl A. (Ed), CRC Press, Bocca Raton, FL
    • Gaubatz J.W. Genomic Instability During Aging of Postmitotic Mammalian Cells. In: Macieira-Coelhl A. (Ed). Molecular Basis of Aging (1995), CRC Press, Bocca Raton, FL 71-131
    • (1995) Molecular Basis of Aging , pp. 71-131
    • Gaubatz, J.W.1
  • 53
    • 0030982861 scopus 로고    scopus 로고
    • Introduction, distribution, and removal of 7-methylguanine in different liver chromatin fractions of young and old mice
    • Gaubatz J.W., and Tan B.H. Introduction, distribution, and removal of 7-methylguanine in different liver chromatin fractions of young and old mice. Mutat. Res. 375 (1997) 25-35
    • (1997) Mutat. Res. , vol.375 , pp. 25-35
    • Gaubatz, J.W.1    Tan, B.H.2
  • 54
    • 0019617451 scopus 로고
    • DNA damage as the primary cause of aging
    • Gensler H.L., and Bernstein H. DNA damage as the primary cause of aging. Q. Rev. Biol. 56 (1981) 279-303
    • (1981) Q. Rev. Biol. , vol.56 , pp. 279-303
    • Gensler, H.L.1    Bernstein, H.2
  • 56
    • 0023820268 scopus 로고
    • 32P-adduct assay: comparative recoveries of structurally diverse DNA adducts in the various enhancement procedures
    • 32P-adduct assay: comparative recoveries of structurally diverse DNA adducts in the various enhancement procedures. Carcinogenesis 9 (1988) 1687-1693
    • (1988) Carcinogenesis , vol.9 , pp. 1687-1693
    • Gupta, R.C.1    Earley, K.2
  • 57
    • 0025342918 scopus 로고
    • Age-dependent covalent alterations (I-compounds) in rat liver mitochondrial DNA
    • Gupta K.P., van Golen K.L., Randerath E., and Randerath K. Age-dependent covalent alterations (I-compounds) in rat liver mitochondrial DNA. Mutat. Res. 237 (1990) 17-27
    • (1990) Mutat. Res. , vol.237 , pp. 17-27
    • Gupta, K.P.1    van Golen, K.L.2    Randerath, E.3    Randerath, K.4
  • 58
    • 0024988560 scopus 로고
    • Quantitative changes in T cell DNA methylation occur during differentiation and ageing
    • Golbus J., Palella T.D., and Richardson B.C. Quantitative changes in T cell DNA methylation occur during differentiation and ageing. Eur. J. Immunol. 20 (1990) 1869-1872
    • (1990) Eur. J. Immunol. , vol.20 , pp. 1869-1872
    • Golbus, J.1    Palella, T.D.2    Richardson, B.C.3
  • 59
    • 0029063483 scopus 로고
    • Changes in the methylation pattern of the c-myc gene during in vitro aging of IMR90 human embryonic fibroblasts
    • Halle J.P., Schmidt C., and Adam G. Changes in the methylation pattern of the c-myc gene during in vitro aging of IMR90 human embryonic fibroblasts. Mutat. Res. 316 (1995) 157-171
    • (1995) Mutat. Res. , vol.316 , pp. 157-171
    • Halle, J.P.1    Schmidt, C.2    Adam, G.3
  • 60
    • 0026456852 scopus 로고
    • The measurement of oxidaitve damage to DNA by HPLC and GC/MS techniques
    • Halliwell B., and Dizdaroglu M. The measurement of oxidaitve damage to DNA by HPLC and GC/MS techniques. Free Rad. Biol. Med. 16 (1992) 75-87
    • (1992) Free Rad. Biol. Med. , vol.16 , pp. 75-87
    • Halliwell, B.1    Dizdaroglu, M.2
  • 61
    • 0029824431 scopus 로고    scopus 로고
    • Antioxidants in human health and disease
    • Halliwell B. Antioxidants in human health and disease. Annu. Rev. Nutr. 16 (1996) 33-50
    • (1996) Annu. Rev. Nutr. , vol.16 , pp. 33-50
    • Halliwell, B.1
  • 63
    • 0026775958 scopus 로고
    • Free radical theory of aging
    • Harman D. Free radical theory of aging. Mutat. Res. 275 (1992) 257-266
    • (1992) Mutat. Res. , vol.275 , pp. 257-266
    • Harman, D.1
  • 64
    • 0011555560 scopus 로고    scopus 로고
    • Correlation between deoxyribonucleic acid excision-repair and life-span in a number of mammalian species
    • Hart, R. W., & Setlow, R. B. Correlation between deoxyribonucleic acid excision-repair and life-span in a number of mammalian species. Proc. Natl. Acad. Sci. USA 71, 2169-2173.
    • Proc. Natl. Acad. Sci. USA , vol.71 , pp. 2169-2173
    • Hart, R.W.1    Setlow, R.B.2
  • 65
    • 0025948247 scopus 로고
    • Age-associated accumulation of 8-hydroxydeoxyguanosine in mitochondria DNA of human diaphram
    • Hayakawa M., Torii K., Sugiyama S., Tanaka M., and Ozawa T. Age-associated accumulation of 8-hydroxydeoxyguanosine in mitochondria DNA of human diaphram. Biochem. Biophys. Res. Commun. 179 (1991) 1023-1029
    • (1991) Biochem. Biophys. Res. Commun. , vol.179 , pp. 1023-1029
    • Hayakawa, M.1    Torii, K.2    Sugiyama, S.3    Tanaka, M.4    Ozawa, T.5
  • 66
    • 0027055332 scopus 로고
    • Age-associated oxygen damage and mutations in mitochondrial DNA in human hearts
    • Hayakawa M., Hattori K., Sugiyama S., and Ozawa T. Age-associated oxygen damage and mutations in mitochondrial DNA in human hearts. Biochem. Biophys. Res. Commun. 189 (1992) 979-985
    • (1992) Biochem. Biophys. Res. Commun. , vol.189 , pp. 979-985
    • Hayakawa, M.1    Hattori, K.2    Sugiyama, S.3    Ozawa, T.4
  • 68
    • 0024825979 scopus 로고
    • The relevance of nitrosamine to human cancer
    • Hecht S.S., and Hoffman D. The relevance of nitrosamine to human cancer. Cancer Surv. 8 (1989) 273-294
    • (1989) Cancer Surv. , vol.8 , pp. 273-294
    • Hecht, S.S.1    Hoffman, D.2
  • 70
    • 0029789377 scopus 로고    scopus 로고
    • Oxidative damage to DNA constitiuents by iron-mediated Fenton reactions
    • Henle E.S., Luo Y., Glassmann W., and Linn S. Oxidative damage to DNA constitiuents by iron-mediated Fenton reactions. J. Biol. Chem. 271 (1996) 21177-21186
    • (1996) J. Biol. Chem. , vol.271 , pp. 21177-21186
    • Henle, E.S.1    Luo, Y.2    Glassmann, W.3    Linn, S.4
  • 71
    • 0020354447 scopus 로고
    • Sites and structures of (γ-irradiation-induced DNA strand breaks
    • Henner W.D., Grunberg S.M., and Haseltine W.A. Sites and structures of (γ-irradiation-induced DNA strand breaks. J. Biol. Chem. 257 (1982) 11750-11754
    • (1982) J. Biol. Chem. , vol.257 , pp. 11750-11754
    • Henner, W.D.1    Grunberg, S.M.2    Haseltine, W.A.3
  • 72
    • 0028827265 scopus 로고
    • Age-associated change of 8-hydroxyguanine repair activity in cultured human fibroblasts
    • Hirano T., Yamaguchi Y., Hirano H., and Kasai H. Age-associated change of 8-hydroxyguanine repair activity in cultured human fibroblasts. Biochem. Biophys. Res. Commun. 214 (1995) 1157-1162
    • (1995) Biochem. Biophys. Res. Commun. , vol.214 , pp. 1157-1162
    • Hirano, T.1    Yamaguchi, Y.2    Hirano, H.3    Kasai, H.4
  • 73
    • 0029787813 scopus 로고    scopus 로고
    • 8-Hydroxyguanine levels in nuclear DNA and its repair activity in rat organs associated with age
    • Hirano T., Yamaguchi R., Asami S., Iwamoto N., and Kasai H. 8-Hydroxyguanine levels in nuclear DNA and its repair activity in rat organs associated with age. J. Gerontol. 51A (1996) B303-B307
    • (1996) J. Gerontol. , vol.51 A
    • Hirano, T.1    Yamaguchi, R.2    Asami, S.3    Iwamoto, N.4    Kasai, H.5
  • 74
    • 0021777383 scopus 로고
    • The Significance of DNA Methylation in Cellular aging
    • Woodhead A.D., Blackett A.D., and Hollaender A. (Eds), Plenum Press, New York
    • Holliday R. The Significance of DNA Methylation in Cellular aging. In: Woodhead A.D., Blackett A.D., and Hollaender A. (Eds). The Molecular Biology of Aging: Basic Life Sciences Vol. 35 (1984), Plenum Press, New York 269-284
    • (1984) The Molecular Biology of Aging: Basic Life Sciences , vol.35 , pp. 269-284
    • Holliday, R.1
  • 75
    • 0023279926 scopus 로고
    • The inheritance of epigenetic defects
    • Holliday R. The inheritance of epigenetic defects. Science 238 (1987) 163-170
    • (1987) Science , vol.238 , pp. 163-170
    • Holliday, R.1
  • 76
    • 0026698068 scopus 로고
    • Oxidative and other DNA damages as the basis of aging: a review
    • Holmes G.E., Bernstein C., and Bernstein H. Oxidative and other DNA damages as the basis of aging: a review. Mutat. Res. 275 (1993) 305-315
    • (1993) Mutat. Res. , vol.275 , pp. 305-315
    • Holmes, G.E.1    Bernstein, C.2    Bernstein, H.3
  • 77
    • 0028074224 scopus 로고
    • Evidence for the accumulation of oxidative stress during cellular aging of human diploid fibroblasts
    • Homma Y., Tsunoda M., and Kasai H. Evidence for the accumulation of oxidative stress during cellular aging of human diploid fibroblasts. Biochem. Biophys. Res. Commun. 203 (1994) 1063-1068
    • (1994) Biochem. Biophys. Res. Commun. , vol.203 , pp. 1063-1068
    • Homma, Y.1    Tsunoda, M.2    Kasai, H.3
  • 78
    • 0024596012 scopus 로고
    • Age-related demethylation of mouse satellite DNA is easily detectable by HPLC but not by restriction endonucleases
    • Howlett D., Dalrymple S., and Mays-Hoopes L.L. Age-related demethylation of mouse satellite DNA is easily detectable by HPLC but not by restriction endonucleases. Mutat. Res. 219 (1989) 101-106
    • (1989) Mutat. Res. , vol.219 , pp. 101-106
    • Howlett, D.1    Dalrymple, S.2    Mays-Hoopes, L.L.3
  • 79
    • 0022310512 scopus 로고
    • Chemical changes induced in DNA by ionizing radiation
    • Hutchinson F. Chemical changes induced in DNA by ionizing radiation. Prog. Nucl. Acid Res. 32 (1985) 115-155
    • (1985) Prog. Nucl. Acid Res. , vol.32 , pp. 115-155
    • Hutchinson, F.1
  • 80
    • 0029888579 scopus 로고    scopus 로고
    • Non-linear accumulation of 8-hydroxy-2′-deoxyguanosine, a marker of oxidized DNA-damage, during aging
    • Kaneko T., Tahara S., and Matsuo M. Non-linear accumulation of 8-hydroxy-2′-deoxyguanosine, a marker of oxidized DNA-damage, during aging. Mutat. Res. 316 (1996) 277-285
    • (1996) Mutat. Res. , vol.316 , pp. 277-285
    • Kaneko, T.1    Tahara, S.2    Matsuo, M.3
  • 81
    • 0030962349 scopus 로고    scopus 로고
    • Retarding effect of dietary restriciton of the accumulation of 8- hydroxy-2′-dexoyguanosine in organs of Fischer 344 rats during aging
    • Kaneko T., Tahara S., and Matsuo M. Retarding effect of dietary restriciton of the accumulation of 8- hydroxy-2′-dexoyguanosine in organs of Fischer 344 rats during aging. Free Rad. Biol. Med. 23 (1997) 76-81
    • (1997) Free Rad. Biol. Med. , vol.23 , pp. 76-81
    • Kaneko, T.1    Tahara, S.2    Matsuo, M.3
  • 82
    • 0019331557 scopus 로고
    • Hypoxanthine in deoxyribonucleic acid: generation by heat-induced hydrolysis of adenine residues and release in free form by a deoxyribonucleic acid glycosylase from calf thymus
    • Karran P., and Lindahl T. Hypoxanthine in deoxyribonucleic acid: generation by heat-induced hydrolysis of adenine residues and release in free form by a deoxyribonucleic acid glycosylase from calf thymus. Biochemistry 19 (1980) 6005-6011
    • (1980) Biochemistry , vol.19 , pp. 6005-6011
    • Karran, P.1    Lindahl, T.2
  • 83
    • 0022595663 scopus 로고
    • Absence of deoxyuridine and 5-hyroxymethyldeoxyuridine in the DNA from three tissues of mice of various ages
    • Kirsh M.E., Cutler R.G., and Hartman P.E. Absence of deoxyuridine and 5-hyroxymethyldeoxyuridine in the DNA from three tissues of mice of various ages. Mech. Ageing Dev. 35 (1986) 71-77
    • (1986) Mech. Ageing Dev. , vol.35 , pp. 71-77
    • Kirsh, M.E.1    Cutler, R.G.2    Hartman, P.E.3
  • 84
    • 0027365312 scopus 로고
    • Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species
    • Ku H.-H., Brunk U.T., and Sohal R.S. Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species. Free Rad. Biol. Med. 15 (1993) 621-627
    • (1993) Free Rad. Biol. Med. , vol.15 , pp. 621-627
    • Ku, H.-H.1    Brunk, U.T.2    Sohal, R.S.3
  • 85
    • 0023388315 scopus 로고
    • The formation of reactive intermediates of glucose-6-phosphate and lysine capable of rapidly reacting with DNA
    • Lee A.T., and Cerami A. The formation of reactive intermediates of glucose-6-phosphate and lysine capable of rapidly reacting with DNA. Mutat. Res. 179 (1987) 151-158
    • (1987) Mutat. Res. , vol.179 , pp. 151-158
    • Lee, A.T.1    Cerami, A.2
  • 86
    • 0023476062 scopus 로고
    • Elevated glucose-6-phophate levels are associated with plasmid mutations in vivo
    • Lee A.T., and Cerami A. Elevated glucose-6-phophate levels are associated with plasmid mutations in vivo. Proc. Natl. Acad. Sci. USA 84 (1987) 8311-8314
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 8311-8314
    • Lee, A.T.1    Cerami, A.2
  • 87
    • 0025355314 scopus 로고
    • In vitro and in vivo reactions of nucleic acids with reducing sugars
    • Lee A.T., and Cerami A. In vitro and in vivo reactions of nucleic acids with reducing sugars. Mutat. Res. 238 (1990) 185-191
    • (1990) Mutat. Res. , vol.238 , pp. 185-191
    • Lee, A.T.1    Cerami, A.2
  • 88
    • 0025875531 scopus 로고
    • Induction of transposition in response to elevated glucose-6-phosphate levels
    • Lee A.T., and Ceramin A. Induction of transposition in response to elevated glucose-6-phosphate levels. Mutat. Res. 249 (1991) 125-133
    • (1991) Mutat. Res. , vol.249 , pp. 125-133
    • Lee, A.T.1    Ceramin, A.2
  • 89
    • 0025139363 scopus 로고
    • Strain differences of 1-compounds in relation to organ sites of spontaneous tumorigenesis and non-neoplastic renal disease in mice
    • Li D., and Randerath K. Strain differences of 1-compounds in relation to organ sites of spontaneous tumorigenesis and non-neoplastic renal disease in mice. Carcinogenesis 11 (1990) 251-255
    • (1990) Carcinogenesis , vol.11 , pp. 251-255
    • Li, D.1    Randerath, K.2
  • 90
    • 0025326795 scopus 로고
    • Association between diet and age-related DNA modifications (I-compounds) in rat liver and kidney
    • Li D., and Randerath K. Association between diet and age-related DNA modifications (I-compounds) in rat liver and kidney. Cancer Res. 50 (1990) 3991-3996
    • (1990) Cancer Res. , vol.50 , pp. 3991-3996
    • Li, D.1    Randerath, K.2
  • 91
    • 0025634165 scopus 로고
    • Species and tissue specificities of 1 compounds as contrasted with carcinogen adducts in liver, kidney and skin of Sprague-Dawley rats, ICR mice and Syrian hamsters
    • Li D., Xu D., and Randerath K. Species and tissue specificities of 1 compounds as contrasted with carcinogen adducts in liver, kidney and skin of Sprague-Dawley rats, ICR mice and Syrian hamsters. Carcinogenesis 11 (1990) 2227-2232
    • (1990) Carcinogenesis , vol.11 , pp. 2227-2232
    • Li, D.1    Xu, D.2    Randerath, K.3
  • 92
    • 0025603018 scopus 로고
    • Persistent reduction of indigenous DNA modification (I-compound) levels in liver DNA from male Fischer rats fed choline-devoid diet and in DNA of resulting neoplasms
    • Li D., Xu D., Chandar N., Lombardi B., and Randerath K. Persistent reduction of indigenous DNA modification (I-compound) levels in liver DNA from male Fischer rats fed choline-devoid diet and in DNA of resulting neoplasms. Cancer Res. 50 (1990) 7577-7580
    • (1990) Cancer Res. , vol.50 , pp. 7577-7580
    • Li, D.1    Xu, D.2    Chandar, N.3    Lombardi, B.4    Randerath, K.5
  • 93
    • 0026723433 scopus 로고
    • Natural dietary ingredients (oats and alfalfa) induce covalent DNA modification (l-compounds) in rat liver and kidney
    • Li D., Chen S., and Randerath K. Natural dietary ingredients (oats and alfalfa) induce covalent DNA modification (l-compounds) in rat liver and kidney. Nutr. Cancer 17 (1992) 205-216
    • (1992) Nutr. Cancer , vol.17 , pp. 205-216
    • Li, D.1    Chen, S.2    Randerath, K.3
  • 94
    • 0026520149 scopus 로고
    • Modulation of DNA modification (l-compound) levels in rat liver and kidney by dietary carbohydrate, protein, fat, vitamin, and mineral content
    • Li D., and Randerath K. Modulation of DNA modification (l-compound) levels in rat liver and kidney by dietary carbohydrate, protein, fat, vitamin, and mineral content. Mutat. Res. 275 (1992) 47-56
    • (1992) Mutat. Res. , vol.275 , pp. 47-56
    • Li, D.1    Randerath, K.2
  • 95
    • 0016257644 scopus 로고
    • Heat-induced deamination of cytosine residues in deoxyribonucleic acid
    • Lindahl T., and Nyberg B. Heat-induced deamination of cytosine residues in deoxyribonucleic acid. Biochemistry 13 (1974) 3405-3410
    • (1974) Biochemistry , vol.13 , pp. 3405-3410
    • Lindahl, T.1    Nyberg, B.2
  • 96
    • 0022037404 scopus 로고
    • Apurinic sites as mutagenic intermediates
    • Loeb L.A. Apurinic sites as mutagenic intermediates. Cell 40 (1985) 483-484
    • (1985) Cell , vol.40 , pp. 483-484
    • Loeb, L.A.1
  • 97
    • 0023015325 scopus 로고
    • Mutagenesis by apurinic/apyrimidinic sites
    • Loeb L.A., and Preston B.D. Mutagenesis by apurinic/apyrimidinic sites. Ann. Rev. Genet. 20 (1986) 201-230
    • (1986) Ann. Rev. Genet. , vol.20 , pp. 201-230
    • Loeb, L.A.1    Preston, B.D.2
  • 98
    • 0026703158 scopus 로고
    • Immunochemical detection of advanced glycosylation end products in vivo
    • Makita Z., Vlassara H., Cerami A., and Bucala R. Immunochemical detection of advanced glycosylation end products in vivo. J. Biol. Chem. 267 (1992) 5133-5138
    • (1992) J. Biol. Chem. , vol.267 , pp. 5133-5138
    • Makita, Z.1    Vlassara, H.2    Cerami, A.3    Bucala, R.4
  • 99
    • 0022671048 scopus 로고
    • Changes of fluorescence spectra of 2′-deoxyguanosine in aqueous solution by radiation
    • Mandal P.C., and Yamamoto O. Changes of fluorescence spectra of 2′-deoxyguanosine in aqueous solution by radiation. Biochem. Int. 12 (1986) 235-242
    • (1986) Biochem. Int. , vol.12 , pp. 235-242
    • Mandal, P.C.1    Yamamoto, O.2
  • 100
    • 0003082567 scopus 로고
    • Nucleic Acid Modification by N-Nitroso Compounds
    • Grover L.P. (Ed), CRC Press, Boca Raton, FL
    • Margison G.P., and O'Connor P.J. Nucleic Acid Modification by N-Nitroso Compounds. In: Grover L.P. (Ed). Chemical Carcinogens and DNA Vol. 1 (1979), CRC Press, Boca Raton, FL 111-159
    • (1979) Chemical Carcinogens and DNA , vol.1 , pp. 111-159
    • Margison, G.P.1    O'Connor, P.J.2
  • 101
    • 0020803419 scopus 로고
    • Methylation and rearrangement of mouse intracisternal A particle genes in development, aging and myeloma
    • Mays-Hoopes L.L., Brown A., and Huang C.C. Methylation and rearrangement of mouse intracisternal A particle genes in development, aging and myeloma. Mol. Cell. Bio. 3 (1983) 1371-1380
    • (1983) Mol. Cell. Bio. , vol.3 , pp. 1371-1380
    • Mays-Hoopes, L.L.1    Brown, A.2    Huang, C.C.3
  • 102
    • 0022922305 scopus 로고
    • Decreased methylation of the major long interspersed repeated DNA during aging and in myeloma cells
    • Mays-Hoopes L.L., Chao W., Butcher H.C., and Huang C.C. Decreased methylation of the major long interspersed repeated DNA during aging and in myeloma cells. Dev. Genet. 7 (1986) 65-73
    • (1986) Dev. Genet. , vol.7 , pp. 65-73
    • Mays-Hoopes, L.L.1    Chao, W.2    Butcher, H.C.3    Huang, C.C.4
  • 103
    • 0024589528 scopus 로고
    • Age-related changes in DNA methylation: Do they represent continued developmental changes?
    • Mays-Hoopes L.L. Age-related changes in DNA methylation: Do they represent continued developmental changes?. Intl. Rev. Cytol. 114 (1989) 181-220
    • (1989) Intl. Rev. Cytol. , vol.114 , pp. 181-220
    • Mays-Hoopes, L.L.1
  • 105
    • 0019519171 scopus 로고
    • Searches for ulitmate chemical carcinogens and their reactions with cellular macromolecules
    • Miller E.C., and Miller J.A. Searches for ulitmate chemical carcinogens and their reactions with cellular macromolecules. Cancer 47 (1981) 2327-2345
    • (1981) Cancer , vol.47 , pp. 2327-2345
    • Miller, E.C.1    Miller, J.A.2
  • 106
    • 0021329156 scopus 로고
    • A two-step hypothesis on the mechanism of in vitro cell aging: cell differentiation followed by intrinsic mitochondrial muatgenesis
    • Miquel J.G., and Fleming J.E. A two-step hypothesis on the mechanism of in vitro cell aging: cell differentiation followed by intrinsic mitochondrial muatgenesis. Exp. Gerontol. 19 (1984) 31-36
    • (1984) Exp. Gerontol. , vol.19 , pp. 31-36
    • Miquel, J.G.1    Fleming, J.E.2
  • 107
    • 0016611279 scopus 로고
    • Formation of N-nitrosos compounds: chemistry, kinetics, and in vivo occurence
    • Mirvish S.S. Formation of N-nitrosos compounds: chemistry, kinetics, and in vivo occurence. Toxicol. Appl. Pharmacol. 31 (1973) 325-351
    • (1973) Toxicol. Appl. Pharmacol. , vol.31 , pp. 325-351
    • Mirvish, S.S.1
  • 108
    • 0027351670 scopus 로고
    • Regulation of repair of alkylation damage in mammalian genomes
    • Mitra S., and Kaina B. Regulation of repair of alkylation damage in mammalian genomes. Prog. Nucl. Acids Res. Mol. Biol. 44 (1993) 109-143
    • (1993) Prog. Nucl. Acids Res. Mol. Biol. , vol.44 , pp. 109-143
    • Mitra, S.1    Kaina, B.2
  • 109
    • 0031283012 scopus 로고    scopus 로고
    • 32P]ATP mediates formation of 8-hydroxy-2′-deoxyguanosine from 2′- deoxyguanosine, a possible problem in the postlabeling assay
    • 32P]ATP mediates formation of 8-hydroxy-2′-deoxyguanosine from 2′- deoxyguanosine, a possible problem in the postlabeling assay. Carcinogenesis 18 (1997) 2415-2419
    • (1997) Carcinogenesis , vol.18 , pp. 2415-2419
    • Moller, L.1    Hofer, T.2
  • 111
    • 0027759243 scopus 로고
    • Human aging is associated with various point mutations in tRNA genes of mitochondrial DNA
    • Munscher C., Muller-Hocker J., and Kadenbach B. Human aging is associated with various point mutations in tRNA genes of mitochondrial DNA. Biol. Chem. Hoppe Seyler 374 (1993) 1099-1104
    • (1993) Biol. Chem. Hoppe Seyler , vol.374 , pp. 1099-1104
    • Munscher, C.1    Muller-Hocker, J.2    Kadenbach, B.3
  • 112
    • 0026465074 scopus 로고
    • 7-Methylguanine levels in DNA of smokers' and non-smokers' total white blood cells, grandulocytes, and lymphocytes
    • Mustonen R., and Hemminki K. 7-Methylguanine levels in DNA of smokers' and non-smokers' total white blood cells, grandulocytes, and lymphocytes. Carcinogenesis 13 (1992) 1951-1955
    • (1992) Carcinogenesis , vol.13 , pp. 1951-1955
    • Mustonen, R.1    Hemminki, K.2
  • 114
    • 0024342545 scopus 로고
    • Endogenous virus genomes become hypomethylated tissue-specifically during aging process in C57BL mice
    • Ono T., Shinya K., Uehara Y., and Okada S. Endogenous virus genomes become hypomethylated tissue-specifically during aging process in C57BL mice. Mech. Ageing Dev. 50 (1989) 27-36
    • (1989) Mech. Ageing Dev. , vol.50 , pp. 27-36
    • Ono, T.1    Shinya, K.2    Uehara, Y.3    Okada, S.4
  • 115
    • 0028220114 scopus 로고
    • Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster
    • Orr W.C., and Sohal R.S. Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 263 (1994) 1128-1130
    • (1994) Science , vol.263 , pp. 1128-1130
    • Orr, W.C.1    Sohal, R.S.2
  • 116
    • 0025321765 scopus 로고
    • Stability of DNA methylation of X-chromosome genes during aging
    • Pagani F., Toniolo D., and Vergani C. Stability of DNA methylation of X-chromosome genes during aging. Somatic Cell Mol. Genet. 16 (1990) 79-84
    • (1990) Somatic Cell Mol. Genet. , vol.16 , pp. 79-84
    • Pagani, F.1    Toniolo, D.2    Vergani, C.3
  • 117
    • 0000628634 scopus 로고
    • 7-methylguanine adducts in DNA are normally present at high levels and increase on aging: analysis by HPLC with electrochemical detection
    • Park J.W., and Ames B.N. 7-methylguanine adducts in DNA are normally present at high levels and increase on aging: analysis by HPLC with electrochemical detection. Proc. Natl. Acad. Sci. USA 85 (1988) 7467-7470
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 7467-7470
    • Park, J.W.1    Ames, B.N.2
  • 119
    • 0024523950 scopus 로고
    • Detection of DNA adducts by high-performance chromatography with electrochemical detection
    • Park J., Cundy K.C., and Ames B.N. Detection of DNA adducts by high-performance chromatography with electrochemical detection. Carcinogenesis 10 (1989) 827-832
    • (1989) Carcinogenesis , vol.10 , pp. 827-832
    • Park, J.1    Cundy, K.C.2    Ames, B.N.3
  • 120
    • 0028988415 scopus 로고
    • Identification of N2-(1-carboxyethyl)guanine (CEG) as a guanine advanced glycosylation end product
    • Papoulis A., Al-Abed Y., and Bucala R. Identification of N2-(1-carboxyethyl)guanine (CEG) as a guanine advanced glycosylation end product. Biochemistry 34 (1995) 648-655
    • (1995) Biochemistry , vol.34 , pp. 648-655
    • Papoulis, A.1    Al-Abed, Y.2    Bucala, R.3
  • 121
    • 0003042780 scopus 로고
    • Alkylation and subsequent repair of DNA after exposure to dimethylnitrosamine and related carcinogens
    • Pegg A.E. Alkylation and subsequent repair of DNA after exposure to dimethylnitrosamine and related carcinogens. Rev. Biochem. Toxicol. 5 (1983) 83-133
    • (1983) Rev. Biochem. Toxicol. , vol.5 , pp. 83-133
    • Pegg, A.E.1
  • 122
    • 0027142423 scopus 로고
    • Imprinting the genome: Imprinted genes, imprinting genes, and a hypothesis for their interaction
    • Peterson K., and Sapienza C. Imprinting the genome: Imprinted genes, imprinting genes, and a hypothesis for their interaction. Ann. Rev. Genet. 27 (1993) 7-31
    • (1993) Ann. Rev. Genet. , vol.27 , pp. 7-31
    • Peterson, K.1    Sapienza, C.2
  • 123
    • 0031428480 scopus 로고    scopus 로고
    • Presence and consequence of uracil in preneoplastic DNA from folate/methyl-deficient rats
    • Pogribny L.P., Muskhelishvili L., Miller B.J., and James S.J. Presence and consequence of uracil in preneoplastic DNA from folate/methyl-deficient rats. Carcinogenesis 18 (1997) 2071-2076
    • (1997) Carcinogenesis , vol.18 , pp. 2071-2076
    • Pogribny, L.P.1    Muskhelishvili, L.2    Miller, B.J.3    James, S.J.4
  • 124
    • 0022775652 scopus 로고
    • 32P-postlabeling assay and possible significance for spontaneous tumor induction and aging
    • 32P-postlabeling assay and possible significance for spontaneous tumor induction and aging. Carcinogenesis 7 (1986) 1615-1617
    • (1986) Carcinogenesis , vol.7 , pp. 1615-1617
    • Randerath, K.1    Reddy, M.V.2    Disher, R.M.3
  • 125
    • 0024264520 scopus 로고
    • Organ-specific effects of long term feeding of 2,3,7,8-tetrachlorodibenzo-p- dioxin and 1,2,3,7,8-pentachlorodibenzo-p-dioxin on l-compounds in hepatic and renal DNA of female Sprague-Dawley rats
    • Randerath K., Putman K.L., Randerath E., Mason G., Kelley M., and Safe S. Organ-specific effects of long term feeding of 2,3,7,8-tetrachlorodibenzo-p- dioxin and 1,2,3,7,8-pentachlorodibenzo-p-dioxin on l-compounds in hepatic and renal DNA of female Sprague-Dawley rats. Carcinogenesis 9 (1988) 2285-2289
    • (1988) Carcinogenesis , vol.9 , pp. 2285-2289
    • Randerath, K.1    Putman, K.L.2    Randerath, E.3    Mason, G.4    Kelley, M.5    Safe, S.6
  • 126
    • 0024596014 scopus 로고
    • Age-dependent covalent DNA alterations (l-compounds) in rodent tissues: species, tissue, and sex specificities
    • Randerath K., Liehr J.G., Gladek A., and Randerath E. Age-dependent covalent DNA alterations (l-compounds) in rodent tissues: species, tissue, and sex specificities. Mutat. Res. 219 (1989) 121-133
    • (1989) Mutat. Res. , vol.219 , pp. 121-133
    • Randerath, K.1    Liehr, J.G.2    Gladek, A.3    Randerath, E.4
  • 127
    • 0025363613 scopus 로고
    • Age-related DNA modifications (l-compounds): Modulation by physiological and pathological processes
    • Randerath K., Li D., and Randerath E. Age-related DNA modifications (l-compounds): Modulation by physiological and pathological processes. Mutat. Res. 238 (1990) 245-253
    • (1990) Mutat. Res. , vol.238 , pp. 245-253
    • Randerath, K.1    Li, D.2    Randerath, E.3
  • 130
    • 0027264363 scopus 로고
    • Enhancement of age-related increases in DNA l-compound levels by calorie restriction: comparison of male B-N and F-344 rats
    • Randerath K., Hart R.W., Zhou G.D., Reddy R., Danna T.F., and Randerath E. Enhancement of age-related increases in DNA l-compound levels by calorie restriction: comparison of male B-N and F-344 rats. Mutat. Res. 295 (1993) 31-46
    • (1993) Mutat. Res. , vol.295 , pp. 31-46
    • Randerath, K.1    Hart, R.W.2    Zhou, G.D.3    Reddy, R.4    Danna, T.F.5    Randerath, E.6
  • 131
    • 0027745793 scopus 로고
    • Biomarkers of aging: correlation of DNA l-compound levels with median lifespan of calorically restricted and ad libitum fed rats and mice
    • Randerath K., Zhou G., Hart R.W., Tuturro A., and Randerath K. Biomarkers of aging: correlation of DNA l-compound levels with median lifespan of calorically restricted and ad libitum fed rats and mice. Mutat. Res. 295 (1993) 247-263
    • (1993) Mutat. Res. , vol.295 , pp. 247-263
    • Randerath, K.1    Zhou, G.2    Hart, R.W.3    Tuturro, A.4    Randerath, K.5
  • 132
    • 0027220519 scopus 로고
    • Altered fidelity of a nucleic acid modifying enzyme, T4 polynucleotide kinase, by safrole-induced DNA damage
    • Randerath K., Gupta K.P., and van Golen K.L. Altered fidelity of a nucleic acid modifying enzyme, T4 polynucleotide kinase, by safrole-induced DNA damage. Carciongenesis 14 (1993) 1523-1529
    • (1993) Carciongenesis , vol.14 , pp. 1523-1529
    • Randerath, K.1    Gupta, K.P.2    van Golen, K.L.3
  • 133
    • 0028250528 scopus 로고
    • 32P-postlabeling methods for DNA adduct detection: overview and critical evaluation
    • 32P-postlabeling methods for DNA adduct detection: overview and critical evaluation. Drug Metabol. Rev. 261 (1994) 67-85
    • (1994) Drug Metabol. Rev. , vol.261 , pp. 67-85
    • Randerath, K.1    Randerath, E.A.2
  • 134
    • 0030069695 scopus 로고    scopus 로고
    • Structural origins of bulky oxidative DNA adducts (type II l-compounds) as deduced by oxidation of oligonucleotides of known sequence
    • Randerath K., Randerath E., Smith C.V., and Chang J. Structural origins of bulky oxidative DNA adducts (type II l-compounds) as deduced by oxidation of oligonucleotides of known sequence. Chem. Res. Toxicol. 9 (1996) 247-254
    • (1996) Chem. Res. Toxicol. , vol.9 , pp. 247-254
    • Randerath, K.1    Randerath, E.2    Smith, C.V.3    Chang, J.4
  • 135
    • 0028889564 scopus 로고
    • Determination of 8-oxoguanine in DNA by gas chromatography-mass spectrometry and HPLC-electrochemical detection: overestimation of the background level of the oxidized base by the gas chromatography-mass spectrometry assay
    • Ravanat J.L., Turesky R.J., Gremaud E., Trudel I.J., and Stadler R. Determination of 8-oxoguanine in DNA by gas chromatography-mass spectrometry and HPLC-electrochemical detection: overestimation of the background level of the oxidized base by the gas chromatography-mass spectrometry assay. Chem Res. Toxicol. 8 (1995) 1039-1045
    • (1995) Chem Res. Toxicol. , vol.8 , pp. 1039-1045
    • Ravanat, J.L.1    Turesky, R.J.2    Gremaud, E.3    Trudel, I.J.4    Stadler, R.5
  • 137
    • 0022774562 scopus 로고
    • 32P-postlabeling test for structurally diverse DNA adducts
    • 32P-postlabeling test for structurally diverse DNA adducts. Carcinogenesis 7 (1986) 1543-1551
    • (1986) Carcinogenesis , vol.7 , pp. 1543-1551
    • Reddy, M.V.1    Randerath, K.2
  • 138
    • 0031950474 scopus 로고    scopus 로고
    • Asymmetrical directional mutation pressue in the mitochondrial genome of mammals
    • Reyes A., Gissi C., Pesole G., and Saccone C. Asymmetrical directional mutation pressue in the mitochondrial genome of mammals. Mol. Biol. Evol. 15 (1998) 957-966
    • (1998) Mol. Biol. Evol. , vol.15 , pp. 957-966
    • Reyes, A.1    Gissi, C.2    Pesole, G.3    Saccone, C.4
  • 139
    • 0142034401 scopus 로고
    • Chemistry of nonenzymatic browning
    • Reynolds T.M. Chemistry of nonenzymatic browning. Adv. Food Res. 14 (1965) 165-283
    • (1965) Adv. Food Res. , vol.14 , pp. 165-283
    • Reynolds, T.M.1
  • 140
    • 0023811053 scopus 로고
    • Normal oxidative damage to mitochondrial and nuclear DNA is extensive
    • Richter C., Park J.W., and Ames B.N. Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc. Natl. Acad. Sci. USA 85 (1988) 6465-6467
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 6465-6467
    • Richter, C.1    Park, J.W.2    Ames, B.N.3
  • 141
    • 0025145277 scopus 로고
    • 5-Methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes
    • Rideout III W.M., Coetzee G.A., Olumi A.F., and Jones P.A. 5-Methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes. Science 249 (1990) 1288-1290
    • (1990) Science , vol.249 , pp. 1288-1290
    • Rideout III, W.M.1    Coetzee, G.A.2    Olumi, A.F.3    Jones, P.A.4
  • 142
    • 0020341190 scopus 로고
    • Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction
    • Ryberg B., and Lindahl T. Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction. EMBO J. 1 (1982) 211-216
    • (1982) EMBO J. , vol.1 , pp. 211-216
    • Ryberg, B.1    Lindahl, T.2
  • 145
    • 0031981810 scopus 로고    scopus 로고
    • Involvement of DNA methylation in human carcinogenesis
    • Schmutte C., and Jones P.A. Involvement of DNA methylation in human carcinogenesis. Biol. Chem. 374 (1998) 377-388
    • (1998) Biol. Chem. , vol.374 , pp. 377-388
    • Schmutte, C.1    Jones, P.A.2
  • 147
    • 0019336089 scopus 로고
    • Base modification in adult animal liver DNA and similarity to radiation-induced base modification
    • Sharma R.C., and Yamamoto O. Base modification in adult animal liver DNA and similarity to radiation-induced base modification. Biochem. Biophys. Res. Commun. 96 (1980) 627-662
    • (1980) Biochem. Biophys. Res. Commun. , vol.96 , pp. 627-662
    • Sharma, R.C.1    Yamamoto, O.2
  • 148
    • 0025981359 scopus 로고
    • Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
    • Shibutani S., Takeshita M., and Grollman A.P. Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG. Nature 349 (1991) 431-434
    • (1991) Nature , vol.349 , pp. 431-434
    • Shibutani, S.1    Takeshita, M.2    Grollman, A.P.3
  • 149
    • 0020318869 scopus 로고
    • Variability of DNA methylation patterns during serial passage of human diploid fibroblasts
    • Shmookler Reis R.J., and Goldstein S. Variability of DNA methylation patterns during serial passage of human diploid fibroblasts. Proc. Natl. Acad. Sci. U.S.A. 79 (1982) 3949-3953
    • (1982) Proc. Natl. Acad. Sci. U.S.A. , vol.79 , pp. 3949-3953
    • Shmookler Reis, R.J.1    Goldstein, S.2
  • 150
    • 0025271476 scopus 로고
    • Clonal variation in gene methylation: c-H-ras and (-hCG regions vary independently in human fibroblast linkages
    • Shmookler Reis R.J., Finn G.K., Smith K., and Goldstein S. Clonal variation in gene methylation: c-H-ras and (-hCG regions vary independently in human fibroblast linkages. Mutat. Res. 237 (1990) 45-57
    • (1990) Mutat. Res. , vol.237 , pp. 45-57
    • Shmookler Reis, R.J.1    Finn, G.K.2    Smith, K.3    Goldstein, S.4
  • 151
    • 0031016727 scopus 로고    scopus 로고
    • Effects of nitrous acid treatment of the survival and mutagenesis of Escherichia coli cells lacking base excision repair (hypoxanthine-DNA glycosylase-ALK A protein) and/or nucleotide excision repair
    • Sidorkina O., Saparbaev M., and Laval J. Effects of nitrous acid treatment of the survival and mutagenesis of Escherichia coli cells lacking base excision repair (hypoxanthine-DNA glycosylase-ALK A protein) and/or nucleotide excision repair. Mutagenesis 12 (1997) 23-28
    • (1997) Mutagenesis , vol.12 , pp. 23-28
    • Sidorkina, O.1    Saparbaev, M.2    Laval, J.3
  • 154
    • 0024370267 scopus 로고
    • Genetic instability and aging: theories, facts, and future perspectives
    • Slagboom P.E., and Vijg J. Genetic instability and aging: theories, facts, and future perspectives. Genome 31 (1989) 373-385
    • (1989) Genome , vol.31 , pp. 373-385
    • Slagboom, P.E.1    Vijg, J.2
  • 155
    • 0025305837 scopus 로고
    • Messenger RNA levels and methylation patterns of GAPDH and (-actin genes in rat liver, spleen and brain in relation to aging
    • Slagboom P.E., de Leeuw W.J.F., and Vijg J. Messenger RNA levels and methylation patterns of GAPDH and (-actin genes in rat liver, spleen and brain in relation to aging. Mech. Ageing Dev. 53 (1990) 243-257
    • (1990) Mech. Ageing Dev. , vol.53 , pp. 243-257
    • Slagboom, P.E.1    de Leeuw, W.J.F.2    Vijg, J.3
  • 156
    • 0028268734 scopus 로고
    • Mitochondrial oxidative damage, hydrogen peroxide release, and aging
    • Sohal R.S., and Dubey A. Mitochondrial oxidative damage, hydrogen peroxide release, and aging. Free Rad. Biol. Med. 16 (1994) 621-626
    • (1994) Free Rad. Biol. Med. , vol.16 , pp. 621-626
    • Sohal, R.S.1    Dubey, A.2
  • 157
    • 0028342438 scopus 로고
    • Oxidative damage, mitochondrial oxidant generation and antioxidant defences during aging and in response to food restriction in the mouse
    • Sohal R.S., Ku H.-H., Agarwal S., Forster M.J., and Lal H. Oxidative damage, mitochondrial oxidant generation and antioxidant defences during aging and in response to food restriction in the mouse. Mech. Ageing Dev. 74 (1994) 121-133
    • (1994) Mech. Ageing Dev. , vol.74 , pp. 121-133
    • Sohal, R.S.1    Ku, H.-H.2    Agarwal, S.3    Forster, M.J.4    Lal, H.5
  • 158
    • 0028116159 scopus 로고
    • Effect of age and caloric restriction on DNA oxidative damage in different tissues of C57BL/6 mice
    • Sohal R.S., Agarwal S., Candas M., Forster M.J., and Lai H. Effect of age and caloric restriction on DNA oxidative damage in different tissues of C57BL/6 mice. Mech. Ageing Dev. 76 (1994) 215-224
    • (1994) Mech. Ageing Dev. , vol.76 , pp. 215-224
    • Sohal, R.S.1    Agarwal, S.2    Candas, M.3    Forster, M.J.4    Lai, H.5
  • 160
    • 0025651008 scopus 로고
    • Steady-state levels of 7-methylguanine increase in nuclear DNA of postmitotic mouse tissues during aging
    • Tan B.H., Bancsath A., and Gaubatz J.W. Steady-state levels of 7-methylguanine increase in nuclear DNA of postmitotic mouse tissues during aging. Mutat. Res. 237 (1990) 229-238
    • (1990) Mutat. Res. , vol.237 , pp. 229-238
    • Tan, B.H.1    Bancsath, A.2    Gaubatz, J.W.3
  • 161
    • 0023498493 scopus 로고
    • Endogenous formation of N-nitroso compounds: a current perspective
    • Tannenbaum S.R. Endogenous formation of N-nitroso compounds: a current perspective. IARC Sci. Publ. (1987) 292-296
    • (1987) IARC Sci. Publ. , pp. 292-296
    • Tannenbaum, S.R.1
  • 162
    • 0027535235 scopus 로고
    • Effects of DNA methylation on DNA-binding proteins and gene expression
    • 1993
    • Tate P.H., and Bird A.P. Effects of DNA methylation on DNA-binding proteins and gene expression. Curr. Opin. Genet. Dev. 3 (1993) 226-231 1993
    • (1993) Curr. Opin. Genet. Dev. , vol.3 , pp. 226-231
    • Tate, P.H.1    Bird, A.P.2
  • 163
    • 0025185415 scopus 로고
    • Changes on DNA methylation level during pre- and postnatal periods in mice
    • Tawa R., Ono T., Kurishita A., Okada S., and Hirose S. Changes on DNA methylation level during pre- and postnatal periods in mice. Differentiation 45 (1990) 44-48
    • (1990) Differentiation , vol.45 , pp. 44-48
    • Tawa, R.1    Ono, T.2    Kurishita, A.3    Okada, S.4    Hirose, S.5
  • 165
    • 0002613038 scopus 로고
    • DNA Repair and Replication in Aging Organisms and Cells
    • Finch C.E., and Schneider E.L. (Eds), Van Nostrand Reinhold, New York
    • Tice R.R., and Setlow R.B. DNA Repair and Replication in Aging Organisms and Cells. In: Finch C.E., and Schneider E.L. (Eds). Handbook of the Biology of Aging (1985), Van Nostrand Reinhold, New York 173-193
    • (1985) Handbook of the Biology of Aging , pp. 173-193
    • Tice, R.R.1    Setlow, R.B.2
  • 166
    • 0028272883 scopus 로고
    • Pathogenic effects of advanced glycosylation: Biochemical, biologic, and clinical implications for diabetes and aging
    • Vlassara H., Bucala R., and Striker L. Pathogenic effects of advanced glycosylation: Biochemical, biologic, and clinical implications for diabetes and aging. Lab. Invest. 70 (1994) 138-151
    • (1994) Lab. Invest. , vol.70 , pp. 138-151
    • Vlassara, H.1    Bucala, R.2    Striker, L.3
  • 167
    • 0028893437 scopus 로고
    • Oxidative modification of DNA bases in rat liver and lung during chemical carcinogenesis and aging
    • Wang Y.-J., Ho Y.-S., Lo M.-J., and Lin J.-K. Oxidative modification of DNA bases in rat liver and lung during chemical carcinogenesis and aging. Chem. Biol. Interact. 94 (1995) 135-145
    • (1995) Chem. Biol. Interact. , vol.94 , pp. 135-145
    • Wang, Y.-J.1    Ho, Y.-S.2    Lo, M.-J.3    Lin, J.-K.4
  • 168
    • 0032565577 scopus 로고    scopus 로고
    • Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesions
    • Wang D., Kreutzetr D.A., and Essigmann J.M. Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesions. Mutat. Res. 400 (1998) 99-115
    • (1998) Mutat. Res. , vol.400 , pp. 99-115
    • Wang, D.1    Kreutzetr, D.A.2    Essigmann, J.M.3
  • 169
    • 0002212462 scopus 로고
    • Future Directions in Free Radical Research in Aging
    • Yu B.P. (Ed), CRC Press, Bocca Raton, FL
    • Weindruch R., Warner H.R., and Starke-Reed P.E. Future Directions in Free Radical Research in Aging. In: Yu B.P. (Ed). Free Radicals in Aging (1993), CRC Press, Bocca Raton, FL 269-295
    • (1993) Free Radicals in Aging , pp. 269-295
    • Weindruch, R.1    Warner, H.R.2    Starke-Reed, P.E.3
  • 170
    • 0030572637 scopus 로고    scopus 로고
    • DNA demethylation in vitro: involvement of RNA
    • Weiss A., Keshet J., Razin A., and Cedar H. DNA demethylation in vitro: involvement of RNA. Cell 86 (1996) 709-718
    • (1996) Cell , vol.86 , pp. 709-718
    • Weiss, A.1    Keshet, J.2    Razin, A.3    Cedar, H.4
  • 172
    • 0020638422 scopus 로고
    • DNA methylation decreases in aging but not immortal cells
    • Wilson V.L., and Jones P.A. DNA methylation decreases in aging but not immortal cells. Science 220 (1983) 1055-1057
    • (1983) Science , vol.220 , pp. 1055-1057
    • Wilson, V.L.1    Jones, P.A.2
  • 173
    • 0023664725 scopus 로고
    • Genomic 5-methyldeoxycytidine decreases with age
    • Wilson V.L., Smith R.A., Ma S., and Cutler R.G. Genomic 5-methyldeoxycytidine decreases with age. J. Biol. Chem. 262 (1987) 9948-9951
    • (1987) J. Biol. Chem. , vol.262 , pp. 9948-9951
    • Wilson, V.L.1    Smith, R.A.2    Ma, S.3    Cutler, R.G.4
  • 174
    • 0027477075 scopus 로고
    • In vivo evidence for endogenous DNA alkylation damage as a source of spontaneous mutations in eukaryotic cells
    • Xiao W., and Samson L. In vivo evidence for endogenous DNA alkylation damage as a source of spontaneous mutations in eukaryotic cells. Proc. Natl. Acad. Sci. USA 90 (1993) 2117-2120
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2117-2120
    • Xiao, W.1    Samson, L.2
  • 175
    • 0030446287 scopus 로고    scopus 로고
    • The repair of DNA methylation damage in Saccharomyces cerevisiae
    • Xiao W., Chow B.L., and Rathgeber L. The repair of DNA methylation damage in Saccharomyces cerevisiae. Curr. Genet. 30 (1996) 461-468
    • (1996) Curr. Genet. , vol.30 , pp. 461-468
    • Xiao, W.1    Chow, B.L.2    Rathgeber, L.3
  • 176
    • 0031032817 scopus 로고    scopus 로고
    • Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress
    • Yakes F.M., and VanHouten B. Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc. Natl. Acad. Sci. USA 94 (1997) 514-519
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 514-519
    • Yakes, F.M.1    VanHouten, B.2
  • 178
    • 0000232865 scopus 로고
    • Food restriction research: past and present status
    • Yu B.P. Food restriction research: past and present status. Rev. Biol. Res. Aging 4 (1990) 349-371
    • (1990) Rev. Biol. Res. Aging , vol.4 , pp. 349-371
    • Yu, B.P.1
  • 179
    • 0023335830 scopus 로고
    • Methylation of DNA and its interaction with rat liver gluco-corticoid-receptor complexes
    • Zhavoronkova E.N., and Vanyushin B.F. Methylation of DNA and its interaction with rat liver gluco-corticoid-receptor complexes. Biochemistry 52 (1987) 870-877
    • (1987) Biochemistry , vol.52 , pp. 870-877
    • Zhavoronkova, E.N.1    Vanyushin, B.F.2
  • 180
    • 0031006067 scopus 로고    scopus 로고
    • Mouse DNA methyltransferase (MTase) deletion mutants that retain the catalytic domain display neither de novo nor maintenance methylation activity in vivo
    • Zimmerman C., Guhl E., and Graessmann A. Mouse DNA methyltransferase (MTase) deletion mutants that retain the catalytic domain display neither de novo nor maintenance methylation activity in vivo. Biol. Chem. 378 (1997) 393-405
    • (1997) Biol. Chem. , vol.378 , pp. 393-405
    • Zimmerman, C.1    Guhl, E.2    Graessmann, A.3


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