The mistletoe lectin I-Phloretamide structure reveals a new function of plant lectins

Biochemical and Biophysical Research Communications

Volumn 364, Issue 2, 2007, Pages 195-200

  Meyer, A ^a   Rypniewski, W ^b   Celewicz, L ^c   Erdmann, V A ^d   Voelter, W ^e   Singh, T P ^f   Genov, N ^g   Barciszewski, J ^b   Betzel, Ch ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

^b INSTITUTE OF BIOORGANIC CHEMISTRY   (Poland)

^c ADAM MICKIEWICZ UNIVERSITY   (Poland)

^d FREIE UNIVERSITÄT BERLIN   (Germany)

^e UNIVERSITY OF TÜBINGEN   (Germany)

^f ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^g INSTITUTE OF ORGANIC CHEMISTRY   (Bulgaria)

Author keywords

Plant growth hormone; Viscum album; X ray analysis

Indexed keywords

3 (4 HYDROXYPHENYL) PROPIONIC ACID AMIDE; ARGININE; GROWTH HORMONE; LEUCINE; PROLINE; UNCLASSIFIED DRUG; VALINE; VISCUM ALBUM LECTIN; VISCUM ALBUM LECTIN 1;

AMINO ACID SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; DEFENSE MECHANISM; HORMONE BINDING; PRIORITY JOURNAL; PROTEIN FUNCTION; RIBOSOME; STRUCTURE ANALYSIS; X RAY; XYLEM SAP;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; PLANT PREPARATIONS; PLANT PROTEINS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SUBUNITS; RIBOSOME INACTIVATING PROTEINS, TYPE 2; TOXINS, BIOLOGICAL; VISCUM ALBUM;

VISCUM ALBUM;

EID: 35448934907     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.09.113     Document Type: Article

References (30)

1. Voelter W., Wacker R., Stoeva S., Tsitsilonis R., and Betzel C. Mistletoe lectins, structure and function. Front. Nat. Prod. Chem. 1 (2005) 149-162
2. Endo Y., Chan Y., Lin A., Tsurugi K., and Wool I.G. The cytotoxins alpha-sarcin and ricin retain their specificity when tested on a synthetic oligoribonucleotide (35-mer) that mimics a region of 28 S ribosomal ribonucleic acid. J. Biol. Chem. 263 (1988) 7917-7920
3. Nielsen K., and Boston R.S. Ribosome-inactivating proteins: a plant perspective. Annu. Rev. Plant Physiol. Plant Mol. Biol. 52 (2001) 785-816
4. Eck J., Langer M., Möckel B., Baur A., Rothe M., Zinke H., and Lentzen H. Cloning of the mistletoe lectin gene and characterization of the recombinant A-chain. Eur. J. Biochem. 264 (1999) 775-784
5. J.T. Fisher, Water relations of mistletoes and their hosts, in: M. Calder, P. Bernhardt (Eds.), The Biology of Mistletoes, Acad. Press, Sydney, 1983, pp. 161-184.
6. Ullmann I., Lange L.O., Ziegler H., Ehleringer J., Schulze E.D., and Cowan I.R. Diurnal courses of leaf conductance and transpiration of mistletoes and their hosts in Central Australia. Oecologia 67 (1985) 577-587
7. Barberaki M., and Kintzios S. Accumulation of selected macronutients in mistletoe tissue cultures: effect of medium composition and explant source. Sci. Hortic. 95 (2002) 133-150
8. C.F.v. Tubeuf, Monographie der Mistel, Druck und Verlag von R. Oldenburg, München und Berling, 1923.
9. Rybicka H. Phloretamide in fruitlets of apple tree (Malus domestica). Acta Physiol. Plant. 18 (1996) 359-363
10. Krauspenhaar R., Rypniewski W., Kalkura N., Moore K., DeLucas L., Stoeva S., Mikhailov A., Voelter W., and Betzel C. Crystallisation under microgravity of mistletoe lectin I from Viscum album with adenosine monophosphate and the crystal structure at 1.9 Å resolution. Acta Cryst. D 58 (2002) 1704-1707
11. Mikeska R., Wacker R., Arni R., Singh T.P., Mikhailov A., Gabdoulkhakov A., Voelter W., and Betzel C. Mistletoe lectin I in complex with galactose and lactose reveals distinct sugar-binding properties. Acta Cryst. F 61 (2005) 17-25
12. Crider-Pirkle S., Billingsley P., Faust C., Hardy D.M., Lee V., and Weitlauf H. Cubilin, a binding partner for galectin-3 in the murine utero-placental complex. J. Biol. Chem. 277 (2002) 15904-15912
13. Li Y., Pfuller U., Larsson E.L., Jungvid H., Galaev I.Y., and Mattiasson B. Separation of mistletoe lectins based on the degree of glycosylation using boronate affinity chromatography. J. Chromatogr. 925 (2001) 115-121
14. Z. Otwinowski, W. Minor, Processing of X-ray diffraction data collected in oscillation mode, in: C.W. Carter Jr., R.M. Sweet (Eds.), Methods in Enzymology, Volume 276: Macromolecular Crystallography Part A, Academic Press, New York, 1997, pp. 307-326.
15. Matthews B.W. Solvent content of protein crystals. J. Mol. Biol. 33 2 (1968) 491-497
16. Murshudov G.N., Vagin A.A., and Dodson E.J. Refinement of macromolecular structures by the maximum-likelihood method. Acta Cryst. D 53 (1997) 240-255
17. Vagin A.A., Steiner R.A., Lebedev A.A., Potterton L., McNicholas S., Long F., and Murshudov G.N. Refmac5 dictionary: organization of prior chemical knowledge and guidelines for its use. Acta Crystallogr. D Biol. Crystallogr. 60 (2004) 2184-2195
18. Lyashenko A.V., Zhukhlistova N.E., Gabdoulkhakov A.G., Zhukova Y.N., Voelter W., Zaitsev V.N., Bento I., Stepanova E.V., Kachalova G.S., Koroleva O.V., Cherkashyn E.A., Tishkov V.I., Lamzin V.S., Schirwitz K., Morqunova E.Y., Betzel C., Lindley P.F., and Mikhailov A.M. Purification, crystallization and preliminary X-ray study of the fungal laccase from Cerrena maxima. Acta Cryst. F 62 (2006) 954-957
19. Emsley P., and Cowtan K. Coot: model-building tools for molecular graphics. Acta Crystallogr. D Biol. Crystallogr. 60 (2004) 2126-2132
20. Laskowski R.A., MacArthur M.W., Moss D.S., and Thornton J.M. Procheck: a program to check the stereochemical quality of protein structures. J. Appl. Cryst. 26 (1993) 283-291
21. SYBYL, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, 2005.
22. Chenna R., Sugawara H., Koike T., Lopez R., Gibson T.J., Higgins D.G., and Thompson J.D. Multiple sequence alignment with the Clustal series of programs. Nucleic Acids Res. 31 (2003) 3497-3500
23. ACD/ChemSketch Freeware, Version 10.00, Advanced Chemistry Development Inc., Toronto, ON, Canada, 2006. Available from: .
24. CorelDraw/CorelPaint, Graphics Suite 12, Corel Corporation, Edisonstraße 6 85716, Unterschleißheim, Germany.
25. Villafranca J.E., and Robertus J.D. Ricin B chain is a product of gene duplication. J. Biol. Chem. 256 (1981) 554-556
26. Pascal J.M., Day J.P., Monzingo A.F., Ernst S.R., Robertus J.D., Iglesias R., Pérez Y., Férreras J.M., Citores L., and Gibés T. 2.8-Å crystal structure of a non-toxic type-II ribosome-inactivating protein, ebulin I. Proteins Struct. Funct. Genet. 43 3 (2001) 319-326
27. Rutenber E., Katzin B.J., Ernst S., Collins E.J., Mlsna D., Ready M.P., and Robertus J.D. Crystallographic Refinement of ricin to 2.5 Å. Proteins Struct. Funct. Genet. 10 3 (1991) 240-250
28. Tahirov T.H., Lu T.H., Liaw Y.C., Chen Y.L., and Lin J.Y. Crystal structure of abrin-a at 2.14 Å. J. Mol. Biol. 250 3 (1995) 354-367
29. Burley S.K., and Petsko G.A. Aromatic-aromatic interaction: a mechanism of protein structure stabilization. Science 229 4708 (1985) 23-28
30. Niwa H., Tonevitsky A.G., Agapov I.I., Saward S., Pfüller U., and Palmer R.A. Crystal structure at 3 Å of mistletoe lectin I, a dimeric type-II ribosome-inactivating protein, complexed with galactose. Eur. J. Biochem. 270 (2003) 2739-2749