Comparative effects of mesenchymal progenitor cells, endothelial progenitor cells, or their combination on myocardial infarct regeneration and cardiac function

Journal of Thoracic and Cardiovascular Surgery

Volumn 134, Issue 5, 2007, Pages 1249-1258

  Suuronen, Erik J ^a   Price, Joel ^a   Veinot, John P ^a   Ascah, Kathryn ^a   Kapila, Varun ^a   Guo, Xue Wei ^a   Wong, Serena ^a   Mesana, Thierry G ^a   Ruel, Marc ^a  

^a UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 43; PHOSPHATE BUFFERED SALINE;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTICLE; CELL REGENERATION; COMPARATIVE STUDY; CONTROLLED STUDY; DETERIORATION; ECHOCARDIOGRAPHY; ENDOTHELIUM CELL; HEART FUNCTION; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE CONTRACTILITY; HEART VENTRICLE FAILURE; IMMUNOHISTOCHEMISTRY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MESENCHYMAL STEM CELL; NONHUMAN; PARACRINE SIGNALING; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RAT; STEM CELL TRANSPLANTATION; TREATMENT OUTCOME;

ANIMALS; CELL CULTURE TECHNIQUES; DISEASE MODELS, ANIMAL; ECHOCARDIOGRAPHY; ENDOTHELIAL CELLS; HEART; INJECTIONS, INTRALESIONAL; MESENCHYMAL STEM CELL TRANSPLANTATION; MYOCARDIAL CONTRACTION; MYOCARDIAL INFARCTION; NEOVASCULARIZATION, PHYSIOLOGIC; RATS; RATS, SPRAGUE-DAWLEY; REGENERATION; STEM CELL TRANSPLANTATION; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT;

EID: 35448930673     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jtcvs.2007.07.028     Document Type: Article

References (29)

1. Xaymardan M., Tang L., Zagreda L., Pallante B., Zheng J., Chazen J.L., et al. Platelet-derived growth factor-AB promotes the generation of adult bone marrow-derived cardiac myocytes. Circ Res 94 (2004) e39-e45
2. Gojo S., Gojo N., Takeda Y., Mori T., Abe H., Kyo S., et al. In vivo cardiovasculogenesis by direct injection of isolated adult mesenchymal stem cells. Exp Cell Res 288 (2003) 51-59
3. Dai W., Hale S.L., Martin B.J., Kuang J.Q., Dow J.S., Wold L.E., et al. Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: short- and long-term effects. Circulation 112 (2005) 214-223
4. Janssens S., Dubois C., Bogaert J., Theunissen K., Deroose C., Desmet W., et al. Autologous bone marrow-derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trial. Lancet 367 (2006) 113-121
5. Schachinger V., Assmus B., Britten M.B., Honold J., Lehmann R., Teupe C., et al. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction: final one-year results of the TOPCARE-AMI Trial. J Am Coll Cardiol 44 (2004) 1690-1699
6. Zhang M., Methot D., Poppa V., Fujio Y., Walsh K., and Murry C.E. Cardiomyocyte grafting for cardiac repair: graft cell death and anti-death strategies. J Mol Cell Cardiol 33 (2001) 907-921
7. Davani S., Marandin A., Mersin N., Royer B., Kantelip B., Herve P., et al. Mesenchymal progenitor cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a rat cellular cardiomyoplasty model. Circulation 108 suppl 1 (2003) II253-II258
8. Agbulut O., Vandervelde S., Al Attar N., Larghero J., Ghostine S., Leobon B., et al. Comparison of human skeletal myoblasts and bone marrow-derived CD133+ progenitors for the repair of infarcted myocardium. J Am Coll Cardiol 44 (2004) 458-463
9. Dimmeler S., and Zeiher A.M. Wanted! The best cell for cardiac regeneration. J Am Coll Cardiol 44 (2004) 464-466
10. Suuronen E.J., Wong S., Kapila V., Waghray G., Whitman S.C., Mesana T.G., et al. Generation of CD133(+) cells from CD133(-) peripheral blood mononuclear cells and their properties. Cardiovasc Res 70 (2006) 126-135
11. Urbich C., and Dimmeler S. Endothelial progenitor cells: characterization and role in vascular biology. Circ Res 95 (2004) 343-353
12. He T., Peterson T.E., and Katusic Z.S. Paracrine mitogenic effect of human endothelial progenitor cells: role of interleukin-8. Am J Physiol Heart Circ Physiol 289 (2005) H968-H972
13. Asahara T., and Kawamoto A. Endothelial progenitor cells for postnatal vasculogenesis. Am J Physiol Cell Physiol 287 (2004) C572-C579
14. Hristov M., Erl W., and Weber P.C. Endothelial progenitor cells: mobilization, differentiation, and homing. Arterioscler Thromb Vasc Biol 23 (2003) 1185-1189
15. Dobert N., Britten M., Assmus B., Berner U., Menzel C., Lehmann R., et al. Transplantation of progenitor cells after reperfused acute myocardial infarction: evaluation of perfusion and myocardial viability with FDG-PET and thallium SPECT. Eur J Nucl Med Mol Imaging 31 (2004) 1146-1151
16. Hendrikx M., Hensen K., Clijsters C., Jongen H., Koninckx R., Bijnens E., et al. Recovery of regional but not global contractile function by the direct intramyocardial autologous bone marrow transplantation: results from a randomized controlled clinical trial. Circulation 114 (2006) I101-I107
17. Ruel M., Suuronen E.J., Song J., Kapila V., Gunning D., Waghray G., et al. Effects of off-pump versus on-pump coronary artery bypass grafting on function and viability of circulating endothelial progenitor cells. J Thorac Cardiovasc Surg 130 (2005) 633-639
18. Moadsiri A., Polchert D., Genrich K., Napoles P., Reina E., Turian J., et al. Mesenchymal stem cells enhance xenochimerism in NK-depleted hosts. Surgery 140 (2006) 315-321
19. Nakamura Y., Yasuda T., Weisel R.D., and Li R.K. Enhanced cell transplantation: preventing apoptosis increases cell survival and ventricular function. Am J Physiol Heart Circ Physiol 291 (2006) H939-H947
20. Baklanov D., and Simons M. Arteriogenesis: lessons learned from clinical trials. Endothelium 10 (2003) 217-223
21. Beanlands R.S., Hendry P.J., Masters R.G., deKemp R.A., Woodend K., and Ruddy T.D. Delay in revascularization is associated with increased mortality rate in patients with severe left ventricular dysfunction and viable myocardium on fluorine 18-fluorodeoxyglucose positron emission tomography imaging. Circulation 98 suppl (1998) II51-II56
22. Haas F., Augustin N., Holper K., Wottke M., Haehnel C., Nekolla S., et al. Time course and extent of improvement of dysfunctioning myocardium in patients with coronary artery disease and severely depressed left ventricular function after revascularization: correlation with positron emission tomographic findings. J Am Coll Cardiol 36 (2000) 1927-1934
23. See F., Thomas W., Way K., Tzanidis A., Kompa A., Lewis D., et al. p38 mitogen-activated protein kinase inhibition improves cardiac function and attenuates left ventricular remodeling following myocardial infarction in the rat. J Am Coll Cardiol 44 (2004) 1679-1689
24. He X.Q., Li S.H., Weisel R.D., Chen M.S., Zhong Y., Lu W.Y., et al. Bone marrow mesenchymal stem cells acquire a cardiogenic phenotype via transdifferentiation and cell fusion with cardiomyocytes. Circulation 114 suppl (2006) II412
25. Retuerto M.A., Schalch P., Patejunas G., Carbray J., Liu N., Esser K., et al. Angiogenic pretreatment improves the efficacy of cellular cardiomyoplasty performed with fetal cardiomyocyte implantation. J Thorac Cardiovasc Surg 127 (2004) 1041-1049
26. Fazel S., Tang G.H., Angoulvant D., Cimini M., Weisel R.D., Li R.K., et al. Current status of cellular therapy for ischemic heart disease. Ann Thorac Surg 79 suppl (2005) S2238-S2247
27. Deten A., Volz H.C., Clamors S., Leiblein S., Briest W., Marx G., et al. Hematopoietic stem cells do not repair the infarcted mouse heart. Cardiovasc Res 65 (2005) 52-63
28. Murry C.E., Reinecke H., and Pabon L.M. Regeneration gaps: observations on stem cells and cardiac repair. J Am Coll Cardiol 47 (2006) 1777-1785
29. Kuhlmann M.T., Kirchhof P., Klocke R., Hasib L., Stypmann J., Fabritz L., et al. G-CSF/SCF reduces inducible arrhythmias in the infarcted heart potentially via increased connexin43 expression and arteriogenesis. J Exp Med 203 (2006) 87-97