Genetic structure adds power to detect shizophrenia susceptibility at SLIT3 in the Chinese Han population

Genome Research

Volumn 14, Issue 7, 2004, Pages 1345-1349

  Shi, YongYong ^a,b   Zhao, XinZhi ^a,b   Yu, Lan ^a,b   Tao, Ran ^a,b   Tang, JunXia ^a,b   La, YuJuan ^a,b   Duan, Yun ^a,b   Gao, Bo ^a,b   Gu, NiuFan ^c   Xu, YiFeng ^c   Feng, GuoYin ^c   Zhu, ShaoMin ^d   Liu, HulJun ^d   Salter, Hugh ^e   He, Lin ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^c SHANGHAI MENTAL HEALTH CENTER   (China)

^d Jilin Institute of Mental Health   (China)

^e ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

SLIT PROTEIN;

ARTICLE; CHINESE; CHROMOSOME 5Q; CONTROLLED STUDY; FEMALE; GENE STRUCTURE; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; GEOGRAPHIC DISTRIBUTION; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE MARKER; MINORITY GROUP; POPULATION GENETICS; POPULATION STRUCTURE; PRIORITY JOURNAL; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; CHROMOSOMES, HUMAN, PAIR 5; CLUSTER ANALYSIS; COMPUTER SIMULATION; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; GENETICS, POPULATION; HUMANS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; SCHIZOPHRENIA; VARIATION (GENETICS);

EID: 3543089284     PISSN: 10889051     EISSN: None     Source Type: Journal    
DOI: 10.1101/gr.1758204     Document Type: Article

References (20)

1. Chu, J.Y., Huang, W., Kuang, S.Q., Wang, J.M., Xu, J.J., Chu, Z.T., Yang, Z.Q., Lin, K.Q., Li, P., Wu, M., et al. 1998. Genetic relationship of populations in China. Proc. Natl. Acad. Sci. 95: 11763-11768.
2. Devlin, B., Bacanu, S.A., Roeder, K., Reimherr, F., Wender, P., Galke, B., Novasad, D., Chu, A., Cuenco, K.T., Tiobek, S., et al. 2002. Genome-wide multipoint linkage analyses of multiplex schizophrenia pedigrees from the oceanic nation of Palau. Mol. Psychiatry 7: 689-694.
3. Ding, Y.C., Wooding, S., Harpending, H.C., Chi, H.C., Li, H.P., Fu, Y.X., Pang, J.F., Yao, Y.G., Yu, J.G., Moyzis, R., et al. 2000. Population structure and history in East Asia. Proc. Natl. Acad. Sci. 97: 14003-14006.
4. Hoggart, C.J., Parra, E.J., Shriver, M.D., Bonilla, C., Kittles, R.A., Clayton, D.G., and McKeigue, P.M. 2003. Control of confounding of genetic associations in stratified populations. Am. J. Hum. Genet. 72: 1492-1504.
5. Jin, L. and Su, B. 2000. Natives or immigrants: Modern human origin in East Asia. Nat. Rev. Genet. 1: 126-133.
6. Nguyen-Ba-Charvet, K.T. and Chedotal, A. 2002. Role of Slit proteins in the vertebrate brain. J. Physiol. Paris 96: 91-98.
7. Oota, H., Kitano, T., Jin, F., Yuasa, I., Wang, L., Ueda, S., Saitou, N., and Stoneking, M. 2002. Extreme mtDNA homogeneity in continental Asian populations. Am. J. Phys. Anthropol. 118: 146-153.
8. Pritchard, J.K., Stephens, M., and Donnelly, P. 2000a. Inference of population structure using multilocus genotype data. Genetics 155: 945-959.
9. Pritchard, J.K., Stephens, M., Rosenberg, N.A., and Donnelly, P. 2000b. Association mapping in structured populations. Am. J. Hum. Genet. 67: 170-181.
10. Sham, P.C. and Curtis, D. 1995. An extended transmission/disequilibrium test (TDT) for multi-allele marker loci. Annu. Hum. Genet. 59: 97-105.
11. Stephens, M., Smith, N., and Donnelly, P. 2001. A new statistical method for haplotype reconstruction from population data. Am. J. Hum. Genet. 68: 978-989.
12. Su, B., Xiao, J., Underhill, P., Deka, R., Zhang, W., Akey, J., Huang, W., Shen, D., Lu, D., Luo, J., et al. 1999. Y-Chromosome evidence for a northward migration of modern humans into Eastern Asia during the last Ice Age. Am. J. Hum. Genet. 65: 1718-1724.
13. Terwilliger, J. and Ott, J. 1994. Handbook of human genetic linkage. Johns Hopkins University Press, Baltimore.
14. van den Oord, E.J.C.G. 2002. Association studies in psychiatric genetics: What are we doing? Mol. Psychiatry 7: 827-828.
15. Vargesson, N., Luria, V., Messina, I., Erskine, L., and Laufer, E. 2001. Expression patterns of Slit and Robo family members during vertebrate limb development. Mech. Dev. 106: 175-180.
16. Xie, X. and Ott, J. 1993. Testing linkage disequilibrium between a disease gene and marker loci. Am. J. Hum. Genet. 53: 1107.
17. YiDa, Y. and Cheng, Z. 2002. Chinese surnames: Colony genetics and population distribution. East China Normal University Press, Shanghai.
18. Yuan, W., Rao, Y., Babiuk, R.P., Greer, J.J., Wu, J.Y., and Ornitz, D.M. 2003. A genetic model for a central (septum transversum) congenital diaphragmatic hernia in mice lacking Slit3. Proc. Natl. Acad. Sci. 100: 5217-5222.
19. Zapata, C., Carollo, C., and Rodriguez, S. 2001. Sampling variance and distribution of the D′ measure of overall gametic disequilibrium between multiallelic loci. Ann. Hum. Genet. 65: 395-406.
20. Zhao, T., Zhang, G., Zhu, Y., Zheng, S., Liu, D., Chen, Q., and Zhang, X. 1986. The distribution of immunoglobulin Gm allotypes in forty Chinese populations (in Chinese). Acta. Anthropology Sin. 6: 1-8.