Warfarin: Balancing the benefits and harms

Australian Prescriber

Volumn 27, Issue 4, 2004, Pages

  Borosak, Marija ^a   Choo, Shin ^a   Street, Alison ^a  

^a ALFRED HOSPITAL   (Australia)

Author keywords

Anticoagulation; Haemorrhage; Thromboembolism

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; LOW MOLECULAR WEIGHT HEPARIN; THROMBIN INHIBITOR; WARFARIN;

ANTICOAGULATION; ARTERY THROMBOSIS; BLEEDING; COMORBIDITY; DRUG CHOICE; DRUG CONTRAINDICATION; DRUG DOSE REDUCTION; DRUG INDICATION; DRUG USE; FALLING; GASTROINTESTINAL HEMORRHAGE; HEART ATRIUM FIBRILLATION; HUMAN; MONEY; MORBIDITY; MORTALITY; PRESCRIPTION; PRIMARY PREVENTION; REVIEW; RISK ASSESSMENT; RISK BENEFIT ANALYSIS; RISK FACTOR; SECONDARY PREVENTION; STROKE; THROMBOEMBOLISM; THROMBOSIS; TREATMENT CONTRAINDICATION; TREATMENT INDICATION; VEIN THROMBOSIS;

EID: 3543041296     PISSN: 03128008     EISSN: None     Source Type: Journal    
DOI: 10.18773/austprescr.2004.074     Document Type: Review

References (21)

1. Hirsh J, Dalen JE, Anderson DR, Poller L, Bussey H, Ansell J, et al. Oral anticoagulants: mechanism of action, clinical effectiveness and optimal therapeutic range. Chest 1998;114(5 Suppl):445S-69S.
2. Haemostasis and thrombosis task force for the British committee for standards in haematology. Guidelines on oral anticoagulation: third edition. Br J Haematol 1998;101:374-87.
3. Wolf PA, Dawber TR, Thomas HE Jr, Kannel WB. Epidemiologic assessment of chronic atrial fibrillation and risk of stroke: the Framingham study. Neurology 1978;28: 973-7.
4. Sherman DG, Hart RG, Easton JD. The secondary prevention of stroke in patients with atrial fibrillation. Arch Neurol 1986;43:68-70.
5. Levine MN, Raskob G, Landefeld S, Kearon C. Hemorrhagic complications of anticoagulant treatment. Chest 2001;119 (1 Suppl):108S-21S.
6. Ridker PM, Goldhaber SZ, Danielson E, Rosenberg Y, Eby CS, Deitcher SR, et al. Long-term, low-intensity warfarin therapy for the prevention of recurrent venous thromboembolism. N Engl J Med 2003;348:1425-34.
7. Landefeld CS, Goldman L. Major bleeding in outpatients treated with warfarin: incidence and prediction by factors known at the start of outpatient therapy. Am J Med 1989;87:144-52.
8. Campbell P, Roberts G, Eaton V, Coghlan D, Gallus A. Managing warfarin therapy in the community. Aust Prescr 2001;24:86-9.
9. van der Meer FJ, Rosendaal FR, Vandenbroucke JP, Briet E. Assessment of a bleeding risk index in two cohorts of patients treated with oral anticoagulants. Thromb Haemost 1996;76:12-6.
10. Palareti G, Hirsh J, Legnani C, Manotti C, D'Angelo A, Pengo V, et al. Oral anticoagulation treatment in the elderly: a nested, prospective, case-control study. Arch Intern Med 2000;160:470-8.
11. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham study. Stroke 1991;22:983-8.
12. Laupacis A, Albers G, Dalen J, Dunn MI, Jacobson AK, Singer DE. Antithrombotic therapy in atrial fibrillation. Chest 1998;114(5 Suppl):579S-89S.
13. Stroke prevention in atrial fibrillation study. Final results. Circulation 1991;84:527-39.
14. Froom P, Miron E, Barak M. Oral anticoagulants in the elderly. Br J Haematol 2003;120:526-8.
15. Myers SP. Interactions between complementary medicines and warfarin. Aust Prescr 2002;25:54-6.
16. Man-Son-Hing M, Nichol G, Lau A, Laupacis A. Choosing antithrombotic therapy for elderly patients with atrial fibrillation who are at risk for falls. Arch Intern Med 1999;159:677-85.
17. Man-Son-Hing M, Laupacis A. Balancing the risks of stroke and upper gastrointestinal tract bleeding in older patients with atrial fibrillation. Arch Intern Med 2002;162:541-50.
18. Hylek EM, Skates SJ, Sheehan MA, Singer DE. An analysis of the lowest effective intensity of prophylactic anticoagulation for patients with nonrheumatic atrial fibrillation. N Engl J Med 1996;335:540-6.
19. Secondary prevention in non-rheumatic atrial fibrillation after transient ischaemic attack or minor stroke. EAFT (European Atrial Fibrillation Trial) Study Group. Lancet 1993;342:1255-62.
20. Kearon C, Ginsberg JS, Kovacs MJ, Anderson DR, Wells P, Julian JA, et al. Comparison of low-intensity warfarin therapy with conventional-intensity therapy for long-term prevention of recurrent venous thromboembolism. N Engl J Med 2003;349:631-9.
21. Hylek EM, Go AS, Chang Y, Jensvold NG, Henault LE, Selby JV, et al. Effect of intensity of oral anticoagulation on stroke severity and mortality in atrial fibrillation. N Engl J Med 2003;349:1019-26.