Inhibition of ultraviolet B (UVB)-induced c-fos and c-jun expression in vivo by a tyrosine kinase inhibitor genistein

Carcinogenesis

Volumn 19, Issue 4, 1998, Pages 649-654

  Wang, Yan ^a   E, Yaping ^b   Zhang, Xueshu ^a   Lebwohl, Mark ^a   DeLeo, Vincent ^b   Wei, Huachen ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHILIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GENISTEIN; MESSENGER RNA; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CANCER PREVENTION; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG MECHANISM; ENZYME INHIBITION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; ONCOGENE C FOS; ONCOGENE C JUN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RADIATION CARCINOGENESIS; RNA TRANSCRIPTION; SQUAMOUS CELL CARCINOMA; TOPICAL DRUG ADMINISTRATION;

ANIMALS; ANTICARCINOGENIC AGENTS; DOSE-RESPONSE RELATIONSHIP, RADIATION; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION REGULATION; GENISTEIN; HUMANS; MICE; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; RECEPTOR, EPIDERMAL GROWTH FACTOR; TUMOR CELLS, CULTURED;

EID: 3542992037     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/19.4.649     Document Type: Article

References (45)

1. Herschman,H.R. (1991) Primary response genes induced by growth factors and tumor promoters. Ann. Rev. Biochem., 60, 281-319.
2. Siegfried,Z. and Ziff,E.B. (1989) Transcription activation by serum, PDuF, and TPA through the c-fos DSE: cell type specific requirements for induction. Oncogene, 4, 3-11.
3. Cantley,L.C., Auger,K.R., Carpenter,C., Duckworth,B., Graziani,A., Kapeller,R. and Solotoff,S. (1991) Oncogenes and signal transduction. Cell, 64, 281-302.
4. Lewin,B. (1991) Oncogenic conversion by regulatory changes in transcription factors. Cell, 64, 303-312.
5. Angel,P. and Karin,M. (1991) The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochem. Biophys. Acta, 1072, 129-157.
6. Gutman,A. and Wasylyk,B. (1991) Nuclear targets for transcription regulation by oncogenes. Trends Genet., 7, 49-54.
7. Kovary.K. and Bravo,R. (1991) The Fos and Jun protein families are both required for cell cycle progression in fibroblasts. Mol. Cell. biol., 11, 4466-4472.
8. Lord,K.A., Abdollahi,A., Hoffman-Liebermann,B. and Lieberman,D.A. (1993) Proto-oncogenes of the fos/jun family of transcription factors are positive regulators of myeloid differentiation. Mol. Cell. Biol, 13, 841-851.
9. Hass,S. and Karina,B. (1995) C-fos is involved in the cellular defense against genotoxic effect of UV irradiation. Carcinogenesis, 16, 985-991.
10. Rose-John,S., Fürstenberger,G., Krieg,P., Besemfelder,E., Rincke,G. and Marks, F. (1988) Differential effects of phorbol esters on c-fos and c-myc and ornithine decarboxylase gene expression in mouse skin in vivo. Carcinogenesis, 9, 831-835.
11. Wei,H., Barnes,S. and Wang,Y. (1996) Inhibitory effect of genistein on a tumor promoter-induced c-fos and c-jun expression in mouse skin. Oncol. Rep., 3, 125-128.
12. Crawford,N., Zbinden.I., Amstad,P. and Cerutti,P. (1988) Oxidant stress induces the proto-oncogenes c-fos and c-myc in mouse epidermal cells. Oncogene, 3, 27-32.
13. Amstad,P.A., Kruptiza,G. and Cerutti,P.A. (1992) Mechanism of c-fos induction by active oxygen. Cancer Res., 52, 3952-3960.
14. Hollander,M.C. and Fornace,A.J. (1989) Induction of fos RNA by DNA-damaging agents. Cancer Res., 49, 1687-1692.
15. Akiyama,T., Ishida,J., Nakagawa,S., Ogawara,H., Watanabe,S., Itoh,N. Shibuya,M. and Fukami,Y. (1987) Genistein, a specific inhibitor of tyrosine-specific protein kinases. J. Biol. Chem., 262, 5592-5595.
16. Barnes,S. (1995) Effect of genistein on in vitro and in vivo models of cancer. J. Nutr., 125 (suppl), 777s-783s.
17. Okura,A., Arakawa,H., Oka,H., Yoshinari,T. and Monden,Y. (1988) Effect of genistein on topoisomerase activity and on the growth of [VAL 12] Ha-ras-transformed NIH 3T3 cells. Biochem. Biophys. Res. Commun., 157, 183-189.
18. Zwiller,J., Sassone-Corsi,P, Kakazu,K. and Boyton,A.L. (1991) Inhibition of PDGF-induced c-jun and c-fos expression by a tyrosine protein kinase inhibitor. Oncogene, 6, 219-221.
19. Constantinou,A., Kiguchi,K. and Huberman,E. (1990) Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by genistein. Cancer Res., 50, 2618-2624.
20. Yamashita,Y., Kawada,S. and Nakano,H. (1990) Induction of mammalian topoisomerase II dependent DNA cleavage by non-intercalative flavonoids, genistein and orobol. Biochem. Pharmacol., 39, 737-744.
21. Linassier,C., Pierre,M., Le Peco,J.-B. and Pierre,J. (1990) Mechanisms of action in NIH-3T3 cells of genistein, an inhibitor of EGF receptor tyrosine kinase activity. Biochem. Pharmacol., 39, 187-193.
22. Peterson,G. and Barnes,S. (1991) Genistein inhibition of the growth of human breast cancer cells: independence from estrogen receptors and the multi-drug resistance gene. Biochem. Biophys. Res. Commun., 179, 661-667.
23. Yanagihara,K., Ito,A., Toge,T. and Numoto,M. (1993) Antiproliferative effect of isoflavones on human cancer cell lines established from the gastrointestinal tract. Cancer Res., 53, 5815-5821.
24. Katagiri,K., Katagiri,T., Kajiyama,K., Uehara,Y., Yamaoto,T. and Yoshida,T. (1992) Modulation of monocytic differentiation HL-60 cells by inhibitor of protein tyrosine kinase. Cellular Immunol., 140, 282-294.
25. Fotsis,T., Pepper,M., Adlercerutz,H., Fleischmann,G., Fleischmann,G., Hase,T., Montesano,R., and Schweigerer,L. (1993) Genistein, a dietary-derived inhibitor of in vitro angiogenesis. Proc. Narl Acad. Sci. USA, 90, 2690-2694.
26. Uckun,F.M., Evans,W.E., Forsyth,C.J., Waddick,K.G., Ahlgren,L.T., Chelstrom,L.M., Burkhardt,A., Bolen,J. and Myers,D.E. (1995) Biotherapy of B-cell precursor leukemia by targeting genistein to CD 19-associated tyrosine kinases. Science, 267, 886-891.
27. Wei,H., Wei,L., Frenkel,K., Bowen,R. and Barnes,S. (1993) Inhibition of tumor promoter-induced hydrogen peroxide formation in vitro and in vivo by genistein. Nutr. Cancer, 20, 1-12.
28. Wei,H., Bowen,R., Barnes,S., Cai,Q. and Wang,Y. (1995) Antioxidant and anticarcinotienic properties of the soybean isoflavones genistein. Proc. Soc. Exp. Biol., Med., 208, 124-130.
29. Wei,H., Cai,Q. and Rahn,R.O. (1996) Inhibition of UV light-and Fenton reaction-induced oxidative DNA damage by the isoflavone genistein. Carcinogenesis, 17, 73-77.
30. Roddey,RK., Garmyn,M., Park,H.Y., Bhawan,J. and Gilchrest,B.A. (1994) Ultraviolet irradiation induces c-fos but not c-Ha-ras proto-oncogene expression in human epidermis. J. Invest. Dermatol., 102, 296-299.
31. Gillardon,F., Moll,I. and Uhlmann,E. (1995) Inhibition of c-Fos in the UV-irradiated epidermis by topical application of antisense oligodeoxynucleotides suppresses activation of proliferating cell nuclear antigen. Carcinogenesis, 16, 1853-1856.
32. Adler,V., Fuchs,S.Y., Kim,J., Kraft,A., King,M.P., Pelling,J. and Ronai,Z. (1995) Jun-NH2-terminal kinase activation mediated by UV-induced DNA lesions in melanoma and fibroblast cells. Cell Growth Differ., 6, 1437-1446.
33. Dhanwada,K.R., Dicken,M., Neades,R., Davis,R. and Pelling,J.C. (1995) Differential effects of UV-B and UV-C components of solar radiation on MAP kinase signal transduction pathways in epidermal keratinocytes. Oncogene, 11, 1947-1953.
34. Hattori-Nakakuki,Y., Nishigori,C., Okamoto,K., Imamura,S., Hiai,H. and Toyokuni,S. (1994) Formation of 8-hydroxy-2′-deoxyguanosine in epidermis of hairless mice exposed to near-UV. Biochem. Biophys. Res. Commun., 201, 1132-1139.
35. Hattori,N., Nishigori,C., Tanaka,T., Uchida,K., Nikaido,O., Osawa,T., Hiai,H., Imamura,S. and Toyokuni,S. (1996) 8-hydroxy-2′-deoxyguanosine is increased in epidermal cells of hairless mice after chronic ultraviolet B exposure. J. Invest. Dermatol., 107, 733-737.
36. Danielson,PE., Forss-Petter,S., Brow,A.A., Calavetta,L., Douglass,J., Milner,R.J. and Suteliffe,J. (1988) G. p1B15: a cDNA clone of the rat mRNA encoding cyclophilin. DNA, 7, 261-267.
37. Devary,Y., Gottlieb,R.A., Smeal,T. and Karin,M. (1992) The mammalian ultraviolet response is triggered by activation of Src tyrosine kinases. Cell, 71, 1081-1091.
38. Miller,C.C., Hale,P. and Pentland,A.P. (1994) Ultraviolet B injury increases prostaglandin synthesis through a tyrosine kinase-dependent pathway. J. Biol. Chem., 269, 3529-3533.
39. Warmuth,I., Harth,Y., Matsui,M.S., Wang,N. and DeLeo,V.A. (1994) Ultraviolet radiation induces phosphorylation of the epidermal growth factor receptor. Cancer Res., 54, 374-376.
40. Puri,P.L., Avantaggiati,M.L., Burgio,V.L., Chirillo,P., Collepardo,D., Atoli,G., Balsano,C. and Leverero,M. (1995) Reactive oxygen intermediates (ROIs) are involved in the intracellular transduction of angiotensin II signal in c2c12 cells. Ann. NY Acad. Sci., 27, 394-105.
41. 2 and A-acetyl-L-cysteine regulate expression of c-jun and c-fos in lens system. Exp. Eye Res., 59, 179-190.
42. Crews,C.M., Alessandrini,A. and Erikson,R.L. (1992) The primary structure of MEK, a protein kinase that phosphorylates the ERK gene products. Science, 258, 478-480.
43. 2 stimulate mitogen-activated protein kinase activity in NIH-3T3 cells through the formation of reactive oxygen intermediates. Cancer Rex., 54, 12-15.
44. Yaping,E., Morraro,R., Levit,E., Zhu,H. and DeLeo,V.A. (1996) Ultraviolet radiation induces phosphorylation of the EGF receptor by a novel mechanism. J. Invest. Dernmatol, 106, 821.
45. Gelfand,M.J., Zhang,X., Lebwohl,M. and Wei,H. (1997) Photoprotective effect of the isoflavone genistein in a two stage photo-chemical carcinogenesis model. J. Invest. Dernmatol., 108, 668.