Utilization of a test gradient enhances islet recovery from deceased donor pancreases

Cytotherapy

Volumn 9, Issue 7, 2007, Pages 630-636

  Anderson, J M ^a   Deeds, M C ^a   Armstrong, A S ^a   Gastineau, D A ^a   Kudva, Y C ^a  

^a Mayo Clinic College of Medicine   (United States)

Author keywords

Human islet isolation; Islet purification

Indexed keywords

FICOLL; UNIVERSITY OF WISCONSIN SOLUTION;

ADULT; ARTICLE; CONTROLLED STUDY; DENSITY GRADIENT; DONOR; HUMAN; HUMAN TISSUE; INTERMETHOD COMPARISON; ISOLATION PROCEDURE; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; PURIFICATION; STATISTICAL SIGNIFICANCE;

ADULT; BODY MASS INDEX; CADAVER; CELL SEPARATION; CELL SURVIVAL; CENTRIFUGATION, DENSITY GRADIENT; FICOLL; HUMANS; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MIDDLE AGED; PANCREAS; TISSUE DONORS;

EID: 35349011650     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1080/14653240701392923     Document Type: Article

References (15)

1. Shapiro, AMJ, Lakey, JRT and Ryan, EA (2000) Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med, 343, pp. 230-238.
2. O'Gorman, D., Kin, T. and Murdoch, T. (2005) The standardization of pancreatic donors for islet isolations. Transplantation, 80, pp. 801-806.
3. Gores, PF and Sutherland, DER. (1993) Pancreatic islet transplantation: is purification necessary?. Am J Surg, 166, pp. 538-542.
4. Huang, GC, Zhao, M. and Jones, P. (2004) The development of new density gradient media for purifying human islets and islet-quality assessments. Transplantation, 77, pp. 143-145.
5. London, NJ, James, RF and Bell, PR. (1992) Islet purification. Pancreatic Islet Cell Transplantation: 1892-1992. One Century of Transplantation for Diabetes, pp. 113-123. R. G. Landes, Austin
6. Ichii, H., Pileggi, A. and Molano, RD (2005) Rescue purification maximizes the use of human islet preparations for transplantation. Am J Transplant, 5, pp. 21-30.
7. Ricordi, C., Lacy, PE and Finke, EH (1988) Automated method for isolation of human pancreatic islets. Diabetes, 37, pp. 413-420.
8. Lakey, JRT, Warnock, GL and Shapiro, AMJ (1999) Intraductal collagenase delivery into the human pancreas using syringe loading or controlled perfusion. Cell Transplant, 8, pp. 285-292.
9. Robertson, GSM, Chadwick, D. and Contractor, H. (1992) Storage of human pancreatic digest in University of Wisconsin solution significantly improves subsequent islet purification. Br J Surgery, 79, pp. 899-902.
10. Robertson, GSM, Chadwick, DR and Contractor, H. (1993) The optimization of large-scale density gradient isolation of human islets. Acta Diabetologica, 30, pp. 93-98.
11. Ricordi, C., Gray, DWR and Hering, BJ (1990) Islet isolation assessment in man and large animals. Acta Diabetol Latina, 27, pp. 185-195.
12. Barnett, MJ, McGhee-Wilson, D., Shapiro, AMJ and Lakey, JRT. (2004) Variation in human islet viability based on different membrane integrity stains. Cell Transplant, 13, pp. 481-488.
13. Pileggi, A., Alejandro, R. and Ricordi, C. (2006) Islet transplantation: steady progress and current challenges. Curr Op Org Transplant, 11, pp. 7-13.
14. Wang, W., Upshaw, L. and Strong, DM (2005) Increased oxygen consumption rates in response to high glucose detected by a novel oxygen biosensor system in non-human primate and human islets. J Endocrinol, 185, pp. 445-455.
15. Ichii, H., Inverardi, L. and Pileggi, A. (2005) A novel method for the assessment of cellular composition and beta-cell viability in human islet preparations. Am J Transplant, 5, pp. 1635-1645.