The effect of discontinuation of methylphenidate on neuropsychological performance of children with attention deficit hyperactivity disorder

Psychiatry Investigation

Volumn 4, Issue 2, 2007, Pages 76-83

  Hoare, Peter ^a,b   Sevar, Katherine ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b ROYAL HOSPITAL FOR SICK CHILDREN   (United Kingdom)

Author keywords

Attention deficit hyperactivity disorder; Discontinuation; Methylphenidate; Performance

Indexed keywords

METHYLPHENIDATE;

ADOLESCENT; ARTICLE; ATTENTION DEFICIT DISORDER; CAMBRIDGE NEUROPSYCHOLOGICAL TEST AUTOMATED BATTERY TEST; CHILD; CLINICAL ARTICLE; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DRUG WITHDRAWAL; HUMAN; MALE; NEUROPSYCHOLOGICAL TEST; NEUROPSYCHOLOGY; PSYCHOLOGIC ASSESSMENT; SPATIAL MEMORY; TASK PERFORMANCE; THERAPY EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE; TREATMENT WITHDRAWAL; VISUAL DISCRIMINATION; VISUAL MEMORY; WORKING MEMORY;

EID: 35349008568     PISSN: 17383684     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. DSM IV. Diagnostic and Statistical Manual of Mental Disorders (4th Edition). Washington DC: American Psychiatric Association; 1994.
2. Szatmari P, Offord DR, Boyle MH. Correlates, associated impairments and patterns of service utilization of children with attention deficit disorder: findings from the Ontario Child Health Study. J Child Psychol Psychiatry 1989;30:205-217.
3. Cantwell DP, Baker L. Issues in the classification of child and adolescent psychopathology. J Am Acad Child Adolesc Psychiatry 1988;27:521-533.
4. Weiss G, Hechtman L. Hyperactive Children Growing up: empirical findings and theoretical considerations (2nd ed). New York: Guildford; 1993.
5. Seeman P, Madras BK. Anti-hyperactivity medication: methylphenidate and amphetamine. Mol Psychiatry 1998;3:386-396.
6. Barkley RA. Attention-deficit/hyperactivity disorder, self-regulation, and time: toward a more comprehensive theory. J Dev Behav Pediatr 1997;18:271-279.
7. Alexander GE, DeLong MR, Strick PL. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci 1986;9:357-381.
8. Baddeley AD. Working memory. Science 1992;255:556-559.
9. Mehta MA, Owen AM, Sahakian BJ, Mavaddat N, Pickard JD, Robbins TW. Methylphenidate enhances working memory by modulating discrete frontal and parietal lobe regions in the brain. J Neurosci 2000;20:RC65, 1-6.
10. Beck LH, Bransome ED Jr, Mirsky AF, Rosvold HE, Sarason I. A continuous performance test of brain damage. J Consult Psychol 1956;20:343-350.
11. Klorman R. Cognitive event-related potentials in attention-deficit disorder. J Learn Disabil 1991;24:130-140.
12. Robbins TW. Dissociating executive functions of the prefrontal cortex. In: Roberts AC, Robbins TW, Weiskrantz L, editors. The prefrontal cortex-Executive and cognitive Functions. New York: Oxford University Press; 1998.
13. Luciana M, Nelson CA. Neurodevelopmental assessment of cognitive function using the Cambridge Neuropsychological Testing Automated Battery (CANTAB): validation and future goals. In: Ernst M, Rumsey J, editors. The foundation and future of functional imaging in child psychiatry. Camgridge: Cambridge University Press: 2000.
14. Luciana M, Nelson CA. Assessment of neuropsychological function through use of the Cambridge Neuropsychological Testing Automated Battery: performance in 4- to 12-year-old children. Dev Neuropsychol 2002;22:595-624.
15. Kempton S, Vance A, Maruff P, Luk H, Costin J, Pantelis C. Executive function and attention deficit hyperactivity disorder: stimulant medication and better executive function performance in children. Psychol Med 1999;29:527-538.
16. Swanson J. School-based Assessments and Interventions for ADD Students. Irvine, Calif: KC Publications; 1992.
17. British Picture Vocabulary Scale (BPVS). NFER-Nelson, Windsor, 1982.
18. Johnston C, Pelham WE, Hoza J, Sturges J. Psychostimulant rebound in attention deficit disordered boys. J Am Acad Child Adolesc Psychiatry 1988;27:806-810.
19. Gualtieri CT, Wargin W, Kanoy R, Patrick K, Shen CD, Youngblood W, et al. Clinical studies of methylphenidate serum levels in children and adults. J Am Acad Child Psychiatry 1982;21:19-26.
20. Luciana M, Nelson CA. The functional emergence of prefrontally-guided working memory systems in four-to eight-year-old children. Neuropsychologia 1998;36:273-293.
21. Lowe C, Rabbitt P. Test/re-test reliability of the CANTAB and ISPOCD neuropsychological batteries: theoretical and practical issues. Cambridge Neuropsychological Test Automated Battery. International Study of Post-Operative Cognitive Dysfunction. Neuropsychologia 1998;36:915-923.
22. SPSS Inc. Statistical Package for the Social Sciences (Version 11.5). SPSS Inc., Chicago, 2002.
23. Boucugnani LL, Jones RW. Behaviours analogous to frontal lobe dysfunction in children with attention deficit hyperactivity disorder. Archives of Clinical Neuropsychology 1989;4:161-173.
24. Elliott R, Sahakian BJ, Matthews K, Bannerjea A, Rimmer J, Robbins TW. Effects of methylphenidate on spatial working memory and planning in healthy young adults. Psychopharmacology 1997;131:196-206.
25. Owen AM, Roberts AC, Polkey CE, Sahakian BJ, Robbins TW. Extra-dimensional versus intra-dimensional set-shifting performance following frontal lobe excisions, temporal lobe excisions or amygdalohippocampectomy in man. Neuropsychologia 1991;29:993-1006.
26. Servan-Schreiber D, Printz H, Cohen JD. A network model of catecholamine effects: gain, signal-to-noise ratio, and behavior. Science 1990;249:892-895.
27. Mehta MA, Goodyer IM, Sahakian BJ. Methylphenidate improves working memory and set-shifting in AD/HD: relationships to baseline memory capacity. J Child Psychol Psychiatry 2004; 45:293-305.