메뉴 건너뛰기




Volumn 28, Issue 11, 2007, Pages 1219-1227

The emerging infectious challenge of Clostridium difficile-associated disease in Massachusetts hospitals: Clinical and economic consequences

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BACTERIAL INFECTION; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE ASSOCIATED DISEASE; COHORT ANALYSIS; DATA ANALYSIS; DISEASE SEVERITY; ECONOMIC ASPECT; FEMALE; HEALTH CARE COST; HOSPITAL COST; HOSPITAL DISCHARGE; HOSPITAL INFECTION; HOSPITAL READMISSION; HOSPITALIZATION; HUMAN; INTERNATIONAL CLASSIFICATION OF DISEASES; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; RETROSPECTIVE STUDY;

EID: 35348962496     PISSN: 0899823X     EISSN: None     Source Type: Journal    
DOI: 10.1086/522676     Document Type: Article
Times cited : (285)

References (40)
  • 1
    • 35348993588 scopus 로고    scopus 로고
    • Centers for Disease Control, information for healthcare providers. August, Available at:, Accessed July 9
    • Centers for Disease Control. Clostridium difficile information for healthcare providers. August 2004. Available at: http://www.cdc.gov/ncidod/ dhqp/id_Cdiff.html. Accessed July 9, 2005.
    • (2004) Clostridium difficile
  • 6
    • 0028913365 scopus 로고    scopus 로고
    • Rubin MS, Bodenstein LE, Kent KC. Severe Clostridium difficile colitis. Dis Colon Rectum 1995; 38:350-354.
    • Rubin MS, Bodenstein LE, Kent KC. Severe Clostridium difficile colitis. Dis Colon Rectum 1995; 38:350-354.
  • 7
    • 0028451494 scopus 로고
    • Ten years of prospective Clostridium difficile-associated disease surveillance and treatment at the Minneapolis VA Medical Center, 1982-1991
    • Olson MM, Shanholtzer CJ, Lee JT Jr, Gerding DN. Ten years of prospective Clostridium difficile-associated disease surveillance and treatment at the Minneapolis VA Medical Center, 1982-1991. Infect Control Hosp Epidemiol 1994; 15:371-381.
    • (1994) Infect Control Hosp Epidemiol , vol.15 , pp. 371-381
    • Olson, M.M.1    Shanholtzer, C.J.2    Lee Jr, J.T.3    Gerding, D.N.4
  • 9
    • 0029902523 scopus 로고    scopus 로고
    • Diarrhea and Clostridium difficile-associated diarrhea on a surgical service
    • McCarter MD, Abularrage C, Velasco FT, Davis JM, Daly JM. Diarrhea and Clostridium difficile-associated diarrhea on a surgical service. Arch Surg 1996; 131:1333-1337.
    • (1996) Arch Surg , vol.131 , pp. 1333-1337
    • McCarter, M.D.1    Abularrage, C.2    Velasco, F.T.3    Davis, J.M.4    Daly, J.M.5
  • 10
    • 28844441314 scopus 로고    scopus 로고
    • A predominantly clonal multiinstitutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality
    • Loo VG, Poirier L, Miller MA, et al. A predominantly clonal multiinstitutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality. N Engl J Med 2005; 353:2442-2449.
    • (2005) N Engl J Med , vol.353 , pp. 2442-2449
    • Loo, V.G.1    Poirier, L.2    Miller, M.A.3
  • 11
    • 33644523410 scopus 로고    scopus 로고
    • Clostridium difficile infection in patients discharged from US short-stay hospitals, 1996-2003
    • McDonald LC, Owens M, Jernigan DB. Clostridium difficile infection in patients discharged from US short-stay hospitals, 1996-2003. Emerg Infect Dis 2006; 12:409-15.
    • (2006) Emerg Infect Dis , vol.12 , pp. 409-415
    • McDonald, L.C.1    Owens, M.2    Jernigan, D.B.3
  • 12
    • 0036129083 scopus 로고    scopus 로고
    • the Canadian Nosocomial Infection Surveillance Program. Morbidity, mortality, and healthcare burden of nosocomial Clostridium Difficile-associated diarrhea in Canadian hospitals
    • for the Canadian Hospital Epidemiology Committee
    • Miller MA, Hyland M, Ofner-Agostini M, Gourdeau M, Ishak M for the Canadian Hospital Epidemiology Committee, the Canadian Nosocomial Infection Surveillance Program. Morbidity, mortality, and healthcare burden of nosocomial Clostridium Difficile-associated diarrhea in Canadian hospitals. Infect Control Hosp Epidemiol 2002; 23:137-140.
    • (2002) Infect Control Hosp Epidemiol , vol.23 , pp. 137-140
    • Miller, M.A.1    Hyland, M.2    Ofner-Agostini, M.3    Gourdeau, M.4    Ishak, M.5
  • 13
    • 35348958763 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention, Food and Drug Administration, National Institutes of Health, Atlanta, GA: Department of Health and Human Services;
    • Centers for Disease Control and Prevention, Food and Drug Administration, National Institutes of Health. Report of the Emerging Clostridial Disease Workshop, May 11, 2006: Summary of Proceedings. Atlanta, GA: Department of Health and Human Services; 2006.
    • (2006) Report of the Emerging Clostridial Disease Workshop, May 11, 2006: Summary of Proceedings
  • 14
    • 0028107662 scopus 로고
    • Epidemiology of community-acquired Clostridium difficile-associated diarrhea
    • Hirschhorn LR, Trnka Y, Onderdonk A, Lee MT, Platt R. Epidemiology of community-acquired Clostridium difficile-associated diarrhea. J Infect Dis 1994; 169:127-133.
    • (1994) J Infect Dis , vol.169 , pp. 127-133
    • Hirschhorn, L.R.1    Trnka, Y.2    Onderdonk, A.3    Lee, M.T.4    Platt, R.5
  • 17
    • 0026495166 scopus 로고
    • Clostridium difficile infection: Responses, relapses and re-infections
    • Wilcox MH, Spencer RC. Clostridium difficile infection: responses, relapses and re-infections. J Hosp Infect 1992; 22:85-92.
    • (1992) J Hosp Infect , vol.22 , pp. 85-92
    • Wilcox, M.H.1    Spencer, R.C.2
  • 18
    • 0031958706 scopus 로고    scopus 로고
    • Clostridium difficile infection
    • Kelly CP, LaMont JT. Clostridium difficile infection. Annu Rev Med 1998; 49:375-390.
    • (1998) Annu Rev Med , vol.49 , pp. 375-390
    • Kelly, C.P.1    LaMont, J.T.2
  • 19
    • 0031016896 scopus 로고    scopus 로고
    • Recurrent Clostridium difficile diarrheas: Characteristics of and risk factors for patients enrolled in a prospective, randomized, double-blinded trial
    • Fekety R, McFarland LV, Surawicz CM, Greenberg RN, Elmer GW, Mulligan ME. Recurrent Clostridium difficile diarrheas: characteristics of and risk factors for patients enrolled in a prospective, randomized, double-blinded trial. Clin Infect Dis 1997; 24:324-333.
    • (1997) Clin Infect Dis , vol.24 , pp. 324-333
    • Fekety, R.1    McFarland, L.V.2    Surawicz, C.M.3    Greenberg, R.N.4    Elmer, G.W.5    Mulligan, M.E.6
  • 21
    • 0022348861 scopus 로고
    • Approach to patients with multiple relapses of antibiotic-associated pseudomembranous colitis
    • Tedesco FJ, Gordon D, Fortson WC. Approach to patients with multiple relapses of antibiotic-associated pseudomembranous colitis. Am J Gastroenterol 1985; 80:867-868.
    • (1985) Am J Gastroenterol , vol.80 , pp. 867-868
    • Tedesco, F.J.1    Gordon, D.2    Fortson, W.C.3
  • 22
    • 35348952434 scopus 로고    scopus 로고
    • Massachusetts Fiscal Year 1999-2003 Acute Hospital Case Mix Data Bases, Boston, MA: Massachusetts Division of Health Care Finance and Policy;
    • Massachusetts Fiscal Year 1999-2003 Acute Hospital Case Mix Data Bases, Level III (CD-ROM). Boston, MA: Massachusetts Division of Health Care Finance and Policy; 2001-2005.
    • (2001) Level III (CD-ROM)
  • 24
    • 33847701773 scopus 로고    scopus 로고
    • Clostridium difficile Surveillance Working Group. Recommendations for surveillance of Clostridium difficile-associated disease
    • McDonald LC, Colgnard B, Dubberke E, Song X, Horan T, Kutty PK; Ad Hoc Clostridium difficile Surveillance Working Group. Recommendations for surveillance of Clostridium difficile-associated disease. Infect Control Hosp Epidemiol 2007 ; 28:140-145.
    • (2007) Infect Control Hosp Epidemiol , vol.28 , pp. 140-145
    • McDonald, L.C.1    Colgnard, B.2    Dubberke, E.3    Song, X.4    Horan, T.5    Kutty, P.K.6    Hoc, A.7
  • 25
    • 23844558284 scopus 로고    scopus 로고
    • Risk factors for acquisition of Clostridium difficile-associated diarrhea among outpatients at a cancer hospital
    • Palmore TN, Sohn S, Malak SF, Eagen J, Sepkowitz KA. Risk factors for acquisition of Clostridium difficile-associated diarrhea among outpatients at a cancer hospital. Infect Control Hosp Epidemiol 2005; 26:680-684.
    • (2005) Infect Control Hosp Epidemiol , vol.26 , pp. 680-684
    • Palmore, T.N.1    Sohn, S.2    Malak, S.F.3    Eagen, J.4    Sepkowitz, K.A.5
  • 26
    • 0038449314 scopus 로고    scopus 로고
    • US Department of Labor, Bureau of Labor Statistics, Available at:, Accessed July 14
    • US Department of Labor, Bureau of Labor Statistics. Consumer price indexes. Available at: http://www.bls.gov/cpi/home.htm. Accessed July 14, 2005.
    • (2005) Consumer price indexes
  • 27
    • 85016298913 scopus 로고    scopus 로고
    • Centers for Medicare and Medicaid Services
    • Office of Research, Development, and Information;, Baltimore, MD: US Department of Health and Human Services;
    • Office of Research, Development, and Information; Centers for Medicare and Medicaid Services. Medicare and Medicaid Statistical Supplement, 2002. Baltimore, MD: US Department of Health and Human Services; 2004.
    • (2004) Medicare and Medicaid Statistical Supplement, 2002
  • 28
    • 0036467063 scopus 로고    scopus 로고
    • Health care costs and mortality associated with nosocomial diarrhea due to Clostridium difficile
    • Kyne L, Hamel MB, Polavaram R, et al. Health care costs and mortality associated with nosocomial diarrhea due to Clostridium difficile. Clin Infect Dis 2002; 34:346-353.
    • (2002) Clin Infect Dis , vol.34 , pp. 346-353
    • Kyne, L.1    Hamel, M.B.2    Polavaram, R.3
  • 29
    • 28844494086 scopus 로고    scopus 로고
    • An epidemic, toxin gene-variant strain of Clostridium difficile
    • McDonald LC, Killgore GE, Thompson A, et al. An epidemic, toxin gene-variant strain of Clostridium difficile. N Engl J Med 2005; 353:2433-2441.
    • (2005) N Engl J Med , vol.353 , pp. 2433-2441
    • McDonald, L.C.1    Killgore, G.E.2    Thompson, A.3
  • 30
    • 23844450737 scopus 로고    scopus 로고
    • Clostridium difficile: Responding to a new threat from an old enemy
    • McDonald LC. Clostridium difficile: responding to a new threat from an old enemy. Infect Control Hosp Epidemiol 2005; 26:672-675.
    • (2005) Infect Control Hosp Epidemiol , vol.26 , pp. 672-675
    • McDonald, L.C.1
  • 31
    • 35349026538 scopus 로고    scopus 로고
    • Ohio Department of Health. Final report of rates of Clostridium difficile for Ohio hospitals January 1-December 31, 2006. July 28, 2006. Ohio Department of Health. Available at: http://www.odh.ohio.gov/ASSETS/ 5EA5D246A2AB47868F8C8D6CCAAFEBC/C%20diff%20Final%20Report03012007.pdf. Accessed October 2, 2007.
    • Ohio Department of Health. Final report of rates of Clostridium difficile for Ohio hospitals January 1-December 31, 2006. July 28, 2006. Ohio Department of Health. Available at: http://www.odh.ohio.gov/ASSETS/ 5EA5D246A2AB47868F8C8D6CCAAFEBC/C%20diff%20Final%20Report03012007.pdf. Accessed October 2, 2007.
  • 32
    • 35349006764 scopus 로고    scopus 로고
    • Reportable disease and laboratory findings, 2006
    • Connecticut Department of Public Health
    • Connecticut Department of Public Health. Reportable disease and laboratory findings, 2006. Connecticut Epidemiologist 2006; 26:1-4.
    • (2006) Connecticut Epidemiologist , vol.26 , pp. 1-4
  • 34
    • 32544446901 scopus 로고    scopus 로고
    • Severe Clostridium difficile-associated disease in populations previously at low risk - four states, 2005
    • Centers for Disease Control and Prevention
    • Centers for Disease Control and Prevention. Severe Clostridium difficile-associated disease in populations previously at low risk - four states, 2005. MMWR Morb Mortal Wkly Rep 2005; 54:1201-1205.
    • (2005) MMWR Morb Mortal Wkly Rep , vol.54 , pp. 1201-1205
  • 35
    • 19344364596 scopus 로고    scopus 로고
    • Relatively poor outcome after treatment of Clostridium difficile colitis with metronidazole
    • Musher DM, Aslam S, Logan N, et al. Relatively poor outcome after treatment of Clostridium difficile colitis with metronidazole. Clin Infect Dis 2005; 40:1586-1590.
    • (2005) Clin Infect Dis , vol.40 , pp. 1586-1590
    • Musher, D.M.1    Aslam, S.2    Logan, N.3
  • 36
    • 33747599197 scopus 로고    scopus 로고
    • Improving the treatment ofClostridium difficile-associated disease: Where should we start?
    • Pepin J. Improving the treatment ofClostridium difficile-associated disease: where should we start? Clin Infect Dis 2006; 43:553-555.
    • (2006) Clin Infect Dis , vol.43 , pp. 553-555
    • Pepin, J.1
  • 37
    • 0036147349 scopus 로고    scopus 로고
    • Epidemiology of Clostridium difficile infection in a large population of hospitalized US military veterans
    • Buchner AM, Sonnenberg A. Epidemiology of Clostridium difficile infection in a large population of hospitalized US military veterans. Dig Dis Sci 2002; 47:201-207.
    • (2002) Dig Dis Sci , vol.47 , pp. 201-207
    • Buchner, A.M.1    Sonnenberg, A.2
  • 38
    • 33644837200 scopus 로고    scopus 로고
    • Management and outcomes of a first recurrence of Clostridium difficile-associated disease in Quebec, Canada
    • Pepin J, Routhier S, Gagnon S, Brazeau I. Management and outcomes of a first recurrence of Clostridium difficile-associated disease in Quebec, Canada. Clin Infect Dis 2006; 42:758-764.
    • (2006) Clin Infect Dis , vol.42 , pp. 758-764
    • Pepin, J.1    Routhier, S.2    Gagnon, S.3    Brazeau, I.4
  • 40
    • 35348972824 scopus 로고    scopus 로고
    • HCUPnet, Healthcare Cost and Utilization Project. 2004 nationwide inpatient sample. Rockville, MD: Agency for Healthcare Research and Quality. Available at: http://hcupnet.ahrq.gov/.
    • HCUPnet, Healthcare Cost and Utilization Project. 2004 nationwide inpatient sample. Rockville, MD: Agency for Healthcare Research and Quality. Available at: http://hcupnet.ahrq.gov/.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.