Left ventricular functional assessment in mice: Feasibility of high spatial and temporal resolution ECG-gated blood pool SPECT

Radiology

Volumn 245, Issue 2, 2007, Pages 440-448

  Chin, Bennett B ^a   Metzler, Scott D ^b   Lemaire, Anthony ^a   Curcio, Antonio ^a   Vemulapalli, Sreekanth ^a   Greer, Kim L ^a   Petry, Neil A ^a   Turkington, Timothy G ^a   Coleman, R Edward ^a   Rockman, Howard ^a   Jaszczak, Ronald J ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ELECTROCARDIOGRAM; FEASIBILITY STUDY; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE VOLUME; MOUSE; NONHUMAN; PHANTOM; PRIORITY JOURNAL; PROSPECTIVE STUDY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

ANIMALS; ELECTROCARDIOGRAPHY; FEASIBILITY STUDIES; GATED BLOOD-POOL IMAGING; IMAGE ENHANCEMENT; MICE; MICE, INBRED C57BL; MYOCARDIAL INFARCTION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; VENTRICULAR DYSFUNCTION, LEFT;

EID: 35348950611     PISSN: 00338419     EISSN: None     Source Type: Journal    
DOI: 10.1148/radiol.2452061973     Document Type: Article

References (31)

1. Rockman HA, Koch WJ, Lefkowitz RJ. Seven-transmembrane-spanning receptors and heart function. Nature 2002;415:206-212.
2. Naga Prasad SV, Jayatilleke A, Madamanchi A, Rockman HA. Protein kinase activity of phosphoinositide 3-kinase regulates beta-adrenergic receptor endocytosis. Nat Cell Biol 2005;7:785-796.
3. Badea C, Hedlund LW, Johnson GA. Micro-CT with respiratory and cardiac gating. Med Phys 2004;31:3324-3329.
4. Ruff J, Wiesmann F, Hiller KH, et al. Magnetic resonance microimaging for noninvasive quantification of myocardial function and mass in the mouse. Magn Reson Med 1998;40:43-48.
5. Streif JU, Herold V, Szimtenings M, et al. In vivo time-resolved quantitative motion mapping of the murine myocardium with phase contrast MRI. Magn Reson Med 2003;49:315-321.
6. Wiesmann F, Szimtenings M, Frydrychowicz A, et al. High-resolution MRI with cardiac and respiratory gating allows for accurate in vivo atherosclerotic plaque visualization in the murine aortic arch. Magn Reson Med 2003;50:69-74.
7. Wiesmann F, Ruff J, Engelhardt S, et al. Dobutamine-stress magnetic resonance microimaging in mice: acute changes of cardiac geometry and function in normal and failing murine hearts. Circ Res 2001;88:563-569.
8. Wiesmann F, Ruff J, Hiller KH, Rommel K, Haase A, Neubauer S. Developmental changes of cardiac function and mass assessed with MRI in neonatal, juvenile, and adult mice. Am J Physiol Heart Circ Physiol 2000;278:H652-H657.
9. Zhou R, Pickup S, Glickson JD, Scott CH, Ferrari VA. Assessment of global and regional myocardial function in the mouse using cine and tagged MRI. Magn Reson Med 2003;49:760-764.
10. Siri FM, Jelicks LA, Leinwand LA, Gardin JM. Gated magnetic resonance imaging of normal and hypertrophied murine hearts. Am J Physiol 1997;272:H2394-H2402.
11. Dawson D, Lygate CA, Saunders J, et al. Quantitative 3-dimensional echocardiography for accurate and rapid cardiac phenotype characterization in mice. Circulation 2004;110:1632-1637.
12. Beekman FJ, van der HF, Vastenhouw B, et al. U-SPECT-1: a novel system for submillimetor-resolution tomography with radiolabeled molecules in mice. J Nucl Med 2005;46:1194-1200.
13. Beekman FJ, McElroy DP, Berger F, Gambhir SS, Hoffman EJ, Cherry SR. Towards in vivo nuclear microscopy: iodine-125 imaging in mice using micro-pinholes. Eur J Nucl Mod Mol imaging 2002;29:933-938.
14. Constantinescol A, Choquet P, Monassier L, Israel-Jost V, Mertz L, Elfertak L. Left ventricular perfusion and function in normal mice using pinhole gated single photon emission computed tomography [abstr]. Mol Imaging Biol 2005;7(P):214.
15. Metzler SD, Jaszczak RJ, Patil NH, Vemulapalli S, Akabani G, Chin BB. Molecular imaging of small animals with a triple-head SPECT system using pinhole collimation. IEEE Trans Med Imaging 2005;24:833-862.
16. Chin BB, Lemaire A, Metzler SD, et al. ECG gated ultrahigh resolution pinhole single photon emission computed tomography for in vivo murine myocardial assessment [abstr]. Mol Imaging Biol 2005;7(P):176.
17. Vemulapalli S, Metzler SD, Petry N, et al. In vivo murine 99mTc red blood cell labeling methods for cardiac function and vascular blood pool localization [abstr]. Mol Imaging Biol 2005;7(P):301.
18. Metzler SD, Greer KL, Jaszczak RJ. Determination of mechanical and electronic shifts for pinhole SPECT using a single point source. IEEE Trans Med Imaging 2005;24:361-370.
19. Metzler SD, Bowsher JE, Greer KL, Jaszczak RJ. Analytic determination of the pinhole collimator's point-spread function and RMS resolution with penetration. IEEE Trans Med Imaging 2002;21:878-887.
20. Metzler SD, Bowsher JE, Smith MF, Jaszczak RJ. Analytic determination of pinhole collimator sensitivity with penetration. IEEE Trans Med Imaging 2001;20:730-741.
21. Chin BB, Bloomgarden DC, Xia W, et al. Right and left ventricular volume and ejection fraction by tomographic gated blood-pool scintigraphy. J Nucl Med 1997;38:942-948.
22. Esposito G, Santana LF, Dilly K, et al. Cellular and functional defects in a mouse model of heart failure. Am J Physiol Heart Circ Physiol 2000;279:H3101-H3112.
23. Tanaka N, Dalton N, Mao L, et al. Transthoracic echocardiography in models of cardiac disease in the mouse. Circulation 1996;94:1109-1117.
24. Wu MC, Tang HR, Gao DW, et al. ECG-gated pinhole SPECT in mice with millimeter spatial resolution. IEEE Trans Nucl Sci 2000;47:1218-1221.
25. Liang CS, Frantz RP, Suematsu M, et al. Chronic beta-adrenoceptor blockade prevents the development of beta-adrenergic subsensitivity in experimental right-sided congestive heart failure in dogs. Circulation 1991;84:254-266.
26. Liang CS, Fan TH, Sullebarger JT, Sakamoto S. Decreased adrenergic neuronal uptake activity in experimental right heart failure: a chamber-specific contributor to beta-adrenoceptor downregulation. J Clin Invest 1989;84:1267-1275.
27. Daou D, Van Kriekinge SD, Coaguila C, et al. Automatic quantification of right ventricular function with gated blood pool SPECT. J Nucl Cardiol 2004;11:293-304.
28. Vanhove C, Lahoutte T, Defrise M, Bossuyt A, Franken PR. Reproducibility of left ventricular volume and ejection fraction measurements in rat using pinhole gated SPECT. Eur J Nucl Med Mol Imaging 2005;32:211-220.
29. Tai YC, Ruangma A, Rowland D, et al. Performance evaluation of the microPET focus: a third-generation microPET scanner dedicated to animal imaging. J Nucl Med 2005;46:455-463.
30. Germano G, Kiat H, Kavanagh PB, et al. Automatic quantification of ejection fraction from gated myocardial perfusion SPECT. J Nucl Med 1995;36:2138-2147.
31. Kim SJ, Kim IJ, Kim YS, Kim YK, Shin YB, Kim DS. Automatic quantification of right ventricular volumes and right ventricular ejection fraction with gated blood pool SPECT: comparison of 8- and 16-frame gated blood pool SPECT with first-pass radionuclide angiography. J Nucl Cardiol 2005;12:553-559.