Differential stripping: Introduction of a method to show the penetration of topically applied antifungal substances into the hair follicles

Mycoses

Volumn 50, Issue 6, 2007, Pages 457-462

  Ossadnik, M ^b   Czaika, V ^b   Teichmann, A ^a   Sterry, W ^a   Tietz, H J ^c   Lademann, J ^a   Koch, S ^b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b HELIOS Klinikum Bad Saarow   (Germany)

^c Institut für Pilzerkrankungen Berlin   (Germany)

Author keywords

Brilliant green; Candida albicans; Differential stripping; Follicular penetration; Hair follicle

Indexed keywords

ANTIFUNGAL AGENT; BRILLIANT GREEN;

ADULT; ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; DIFFERENTIAL STRIPPING; DRUG DETERMINATION; DRUG PENETRATION; FUNGUS GROWTH; HAIR FOLLICLE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; INOCULATION; METHODOLOGY; PRIORITY JOURNAL; TOPICAL TREATMENT;

ADMINISTRATION, TOPICAL; ADULT; ANTIFUNGAL AGENTS; BIOPSY; CANDIDA ALBICANS; COLORING AGENTS; CULTURE MEDIA; CYANOACRYLATES; HAIR FOLLICLE; HUMANS; MIDDLE AGED; QUATERNARY AMMONIUM COMPOUNDS; SKIN ABSORPTION;

CANDIDA ALBICANS;

EID: 35348949499     PISSN: 09337407     EISSN: 14390507     Source Type: Journal    
DOI: 10.1111/j.1439-0507.2007.01415.x     Document Type: Article

References (19)

1. Mellström GA, Boman A. Comparative evaluation of permeation testing of protective gloves to solvents: in vitro permeation cells versus in vivo in guinea pigs. Contact Dermatitis 1992 26 : 120 7
2. Sun Q, Tran M, Smith B, Winefordner JD. In situ evaluation of barrier cream performance on human skin using laser-induced breakdown spectroscopy. Contact Dermatitis 2000 43 : 259 63
3. Bouwstra J, Pilgram G, Gooris G, Koerten H, Ponec M. New aspects of skin barrier organization. Skin Pharmacol Appl Skin Physiol 2001 14 : 52 62.
4. Hadgraft J. Modulation of the barrier function of the skin. Skin Pharmacol Appl Skin Physiol 2001 14 : 72 81.
5. Lademann J, Otberg N, Richter H et al. Investigation of follicular penetration of topically applied substances. Skin Pharmacol Appl Skin Physiol 2001 14 : 17 22.
6. Genina EA, Bashkatov AN, Sinichkin YP et al. In vitro and in vivo study of dye diffusion into human skin and hair follicles. J Biomed Opt 2002 7 : 471 7.
7. Ogiso T, Shiraki T, Okajima K, Tanino T, Iwaki M, Wada T. Transfollicular drug delivery: penetration of drugs through human scalp skin and comparison of penetration between scalp and abdominal skins in vitro. J Drug Target 2002 10 : 369 78.
8. Teichmann A, Jacobi U, Weigmann H-J, Sterry W, Lademann J. Reservoir function of the stratum corneum: development of an in vivo method to quantitatively determine the stratum corneum reservoir for topically applied substances. Skin Pharm Skin Phys 2005 18 : 75 80.
9. Otberg N, Richter H, Schaefer H et al. Variations of hair follicle size and distribution in different body sites. J Invest Dermatol 2004 122 : 14 9.
10. Lademann J, Richter H, Schaefer UF, Blume-Peytavi U, Teichmann A, Otberg N, Sterry W. Hair follicles - a long term reservoir for drug delivery. Skin Pharmcol Physiol Skin Pharmacol Physiol 2006 19 : 232 6.
11. Kearney JN, Harnby D, Gowland G, Holland KT. The follicular distribution and abundance of resident bacteria on human skin. J Gen Microbiol 1984 130 : 797 801.
12. Ruppert D. Untersuchung zur Verteilung von Bakterien in der menschlichen Haut. PhD Thesis. Berlin, Germany : Charité-Universitätsmedizin Berlin, 2006.
13. Roth RR, James WD. Microbial ecology of the skin: Ann Rev Microbiol 1988 42 : 441 64.
14. Kyle AA, Dahl MV. Topical treatment for fungal infections. Am J Clin Dermatol 2004 5 : 443 51.
15. Brilliande TW, Hollick GE, Larrsh HW. The efficacies of common dyes in primary isolation media for recovery of pathogenic fungi. Am J Clin Pathol 1979 72 : 868 70.
16. Teichmann A, Jacobi U, Ossadnik M et al. Differential stripping: determination of the amount of topically applied substances penetrated into the hair follicles. J Invest Dermatol 2005 125 : 264 9.
17. Weigmann HJ, Lademann J, Meffert H, Schaefer H, Sterry W. Determination of the horny layer profile by tape stripping in combination with optical spectroscopy in the visible range as a prerequisite to quantify percutaneous absorption. Skin Pharmacol Appl Skin Physiol 1999 12 : 34 45.
18. Lademann J, Weigmann HJ, Schanzer S et al. Optical investigations to avoid the disturbing influences of furrows and wrinkles quantifying penetration of drugs and cosmetics into the skin by tape stripping. J Biomed Opt 2005 10 : 054015.
19. Teichmann A, Ossadnik M, Richter H, Sterry W, Lademann J. Semiquantitative determination of the penetration of a fluorescent hydrogel formulation into the hair follicle with and without follicular closure by microparticles by means of differential stripping. Skin Pharmacol Physiol 2006 19 : 101 5.